ZA903453B - Method for the synthesis of ribonucleic acid(rna) - Google Patents
Method for the synthesis of ribonucleic acid(rna)Info
- Publication number
- ZA903453B ZA903453B ZA903453A ZA903453A ZA903453B ZA 903453 B ZA903453 B ZA 903453B ZA 903453 A ZA903453 A ZA 903453A ZA 903453 A ZA903453 A ZA 903453A ZA 903453 B ZA903453 B ZA 903453B
- Authority
- ZA
- South Africa
- Prior art keywords
- synthesis
- ribonucleic acid
- rna
- target sequence
- sequence
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8901172 | 1989-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA903453B true ZA903453B (en) | 1991-02-27 |
Family
ID=19854626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA903453A ZA903453B (en) | 1989-05-10 | 1990-05-07 | Method for the synthesis of ribonucleic acid(rna) |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5466586A (de) |
| EP (1) | EP0397269B1 (de) |
| JP (1) | JP2839639B2 (de) |
| KR (1) | KR0185376B1 (de) |
| AT (1) | ATE118549T1 (de) |
| AU (1) | AU641159B2 (de) |
| CA (1) | CA2016358C (de) |
| DE (1) | DE69016826T2 (de) |
| DK (1) | DK0397269T3 (de) |
| ES (1) | ES2070995T3 (de) |
| FI (1) | FI102387B1 (de) |
| IE (1) | IE66597B1 (de) |
| ZA (1) | ZA903453B (de) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622820A (en) * | 1988-03-10 | 1997-04-22 | City Of Hope | Method for amplification and detection of RNA and DNA sequences |
| GB8808892D0 (en) * | 1988-04-15 | 1988-05-18 | British Bio Technology | Gene synthesis |
| US5130238A (en) * | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5169766A (en) * | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
| EP0675965A4 (de) * | 1992-01-29 | 1999-01-20 | Hitachi Chemical Co Ltd | Träger zur immobilisierung von polynukleotiden. |
| JP4137996B2 (ja) * | 1992-05-06 | 2008-08-20 | ジェン−プローブ・インコーポレイテッド | 核酸配列増幅方法,組成物及びキット |
| JPH07509361A (ja) * | 1992-07-28 | 1995-10-19 | 日立化成工業株式会社 | 遺伝子検出システム |
| US5712127A (en) * | 1996-04-29 | 1998-01-27 | Genescape Inc. | Subtractive amplification |
| DE19633427C2 (de) * | 1996-08-20 | 2001-10-04 | Hubert S Bernauer | Verfahren zur Synthese von Nukleinsäuremolekülen mit zumindest teilweise vorbestimmter Nukleotidsequenz |
| DE19812103A1 (de) * | 1998-03-19 | 1999-09-23 | Bernauer Annette | Verfahren zur Synthese von Nucleinsäuremolekülen |
| CA2439795A1 (en) * | 2001-03-07 | 2002-09-12 | Biomerieux B.V. | Method for the amplification and detection of dna using a transcription based amplification |
| US20060051740A1 (en) * | 2001-03-07 | 2006-03-09 | Deiman Birgit Alberta L M | Method for the amplification and detection of hbv dna using a transcription based amplification |
| US8137911B2 (en) * | 2001-05-22 | 2012-03-20 | Cellscript, Inc. | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences |
| AU2003303395A1 (en) * | 2001-05-22 | 2004-07-22 | Dahl, Gary, A. | Target-dependent transcription using deletion mutants of n4 rna polymerase |
| US7504215B2 (en) | 2002-07-12 | 2009-03-17 | Affymetrix, Inc. | Nucleic acid labeling methods |
| US20050003369A1 (en) * | 2002-10-10 | 2005-01-06 | Affymetrix, Inc. | Method for depleting specific nucleic acids from a mixture |
| CN1738914A (zh) * | 2002-11-21 | 2006-02-22 | 震源技术公司 | 使用编码双链启动子一条链的引物的方法 |
| US7266295B2 (en) * | 2003-04-17 | 2007-09-04 | Intel Corporation | Modular reconfigurable multi-server system and method for high-speed networking within photonic burst-switched network |
| US7713697B2 (en) * | 2004-08-27 | 2010-05-11 | Gen-Probe Incorporated | Methods and kits for amplifying DNA |
| CA2898814C (en) * | 2004-08-27 | 2015-12-29 | Gen-Probe Incorporated | Single-primer nucleic acid amplification methods |
| ATE545701T1 (de) | 2005-05-17 | 2012-03-15 | Ozgene Pty Ltd | Sequentielles klonierungssystem |
| US8293684B2 (en) * | 2006-11-29 | 2012-10-23 | Exiqon | Locked nucleic acid reagents for labelling nucleic acids |
| US8183359B2 (en) * | 2007-03-01 | 2012-05-22 | Gen-Probe Incorporated | Kits for amplifying DNA |
| US8039214B2 (en) * | 2007-06-29 | 2011-10-18 | Cellscript, Inc. | Synthesis of tagged nucleic acids |
| WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
| WO2010148085A1 (en) | 2009-06-16 | 2010-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rna nanoparticles and methods of use |
| TWI518325B (zh) | 2010-02-04 | 2016-01-21 | 自治醫科大學 | 對alk抑制劑具有先抗性或後抗性癌症的識別、判斷和治療 |
| WO2012019168A2 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
| EP2691101A2 (de) | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Freisetzung und formulierung von manipulierten nukleinsäuren |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
| FR2984357B1 (fr) | 2011-12-16 | 2016-11-18 | Biomerieux Sa | Procede d'amplification transcriptionnelle d'acides nucleiques reunissant des etapes de temperatures differentes |
| CN104114572A (zh) | 2011-12-16 | 2014-10-22 | 现代治疗公司 | 经修饰的核苷、核苷酸和核酸组合物 |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| WO2014081507A1 (en) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Terminally modified rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| WO2015006344A1 (en) * | 2013-07-08 | 2015-01-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for synthesizing selectively labeled rna |
| ES2711168T3 (es) | 2013-08-28 | 2019-04-30 | Becton Dickinson Co | Análisis masivo en paralelo de células individuales |
| EP3047026B1 (de) | 2013-09-17 | 2021-08-18 | The United States of America, as represented by The Secretary, Department of Health & Human Services | Multifunktionelle rna-nanopartikel und verfahren zur verwendung |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
| CA2937432A1 (en) | 2013-11-13 | 2015-05-21 | Universite de Bordeaux | Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof |
| WO2015171827A1 (en) | 2014-05-06 | 2015-11-12 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Triggering rna interference with rna-dna and dna-rna nanoparticles |
| WO2018187373A1 (en) | 2017-04-03 | 2018-10-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Functionally-interdependent shape switching nucleic acid nanoparticles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4766072A (en) * | 1985-07-17 | 1988-08-23 | Promega Corporation | Vectors for in vitro production of RNA copies of either strand of a cloned DNA sequence |
| IL86724A (en) * | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| WO1989006700A1 (en) * | 1988-01-21 | 1989-07-27 | Genentech, Inc. | Amplification and detection of nucleic acid sequences |
| CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
-
1990
- 1990-05-03 IE IE162490A patent/IE66597B1/en not_active IP Right Cessation
- 1990-05-07 ZA ZA903453A patent/ZA903453B/xx unknown
- 1990-05-08 AT AT90201162T patent/ATE118549T1/de not_active IP Right Cessation
- 1990-05-08 DK DK90201162.6T patent/DK0397269T3/da active
- 1990-05-08 ES ES90201162T patent/ES2070995T3/es not_active Expired - Lifetime
- 1990-05-08 DE DE69016826T patent/DE69016826T2/de not_active Expired - Lifetime
- 1990-05-08 EP EP90201162A patent/EP0397269B1/de not_active Expired - Lifetime
- 1990-05-09 AU AU54877/90A patent/AU641159B2/en not_active Expired
- 1990-05-09 FI FI902318A patent/FI102387B1/fi active IP Right Grant
- 1990-05-09 CA CA002016358A patent/CA2016358C/en not_active Expired - Lifetime
- 1990-05-09 KR KR1019900006503A patent/KR0185376B1/ko not_active Expired - Lifetime
- 1990-05-10 JP JP2121066A patent/JP2839639B2/ja not_active Expired - Lifetime
-
1994
- 1994-02-07 US US08/192,756 patent/US5466586A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE901624L (en) | 1990-11-10 |
| JP2839639B2 (ja) | 1998-12-16 |
| EP0397269A1 (de) | 1990-11-14 |
| FI102387B (fi) | 1998-11-30 |
| CA2016358C (en) | 2000-11-28 |
| EP0397269B1 (de) | 1995-02-15 |
| JPH03180184A (ja) | 1991-08-06 |
| US5466586A (en) | 1995-11-14 |
| IE66597B1 (en) | 1996-01-24 |
| DE69016826T2 (de) | 1995-06-08 |
| KR900018376A (ko) | 1990-12-21 |
| AU641159B2 (en) | 1993-09-16 |
| ES2070995T3 (es) | 1995-06-16 |
| DE69016826D1 (de) | 1995-03-23 |
| CA2016358A1 (en) | 1990-11-10 |
| AU5487790A (en) | 1990-11-15 |
| FI902318A0 (fi) | 1990-05-09 |
| KR0185376B1 (ko) | 1999-04-01 |
| ATE118549T1 (de) | 1995-03-15 |
| FI102387B1 (fi) | 1998-11-30 |
| DK0397269T3 (da) | 1995-05-29 |
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