ZA90645B - Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties - Google Patents

Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties

Info

Publication number
ZA90645B
ZA90645B ZA90645A ZA90645A ZA90645B ZA 90645 B ZA90645 B ZA 90645B ZA 90645 A ZA90645 A ZA 90645A ZA 90645 A ZA90645 A ZA 90645A ZA 90645 B ZA90645 B ZA 90645B
Authority
ZA
South Africa
Prior art keywords
pyroglutamyl
thiazolidine
carboxylic acid
derivatives
pharmacological properties
Prior art date
Application number
ZA90645A
Other languages
English (en)
Inventor
Stefano Poli
Poli Stefano
Germano Coppi
Coppi Germano
Lucio Del Corona
Del Corona Lucio
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of ZA90645B publication Critical patent/ZA90645B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
ZA90645A 1989-02-10 1990-01-29 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties ZA90645B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919401A IT1230706B (it) 1989-02-10 1989-02-10 Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.

Publications (1)

Publication Number Publication Date
ZA90645B true ZA90645B (en) 1990-10-31

Family

ID=11157390

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90645A ZA90645B (en) 1989-02-10 1990-01-29 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties

Country Status (18)

Country Link
US (1) US5066644A (fr)
EP (1) EP0382180B1 (fr)
JP (1) JPH02250896A (fr)
KR (1) KR910015574A (fr)
AT (1) ATE106407T1 (fr)
AU (1) AU630661B2 (fr)
CA (1) CA2009709A1 (fr)
DE (2) DE382180T1 (fr)
ES (1) ES2017900T3 (fr)
FI (1) FI900665A7 (fr)
GR (1) GR900300167T1 (fr)
HU (1) HU209602B (fr)
IE (1) IE900261L (fr)
IL (1) IL93197A (fr)
IT (1) IT1230706B (fr)
NO (1) NO900644L (fr)
NZ (1) NZ232437A (fr)
ZA (1) ZA90645B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
US5710288A (en) * 1993-04-21 1998-01-20 Allergan 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents
US5369127A (en) * 1993-04-21 1994-11-29 Allergan, Inc. 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents
WO2015036009A1 (fr) * 2013-09-10 2015-03-19 Polichem S.A. Pidotimod à utiliser dans le traitement de maladies associées à une inflammation
CN111233854A (zh) * 2019-12-30 2020-06-05 常州寅盛药业有限公司 一种匹多莫德杂质的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1492640A (en) * 1975-07-08 1977-11-23 Ucb Sa L-pyroglutamyl-l-prolinamide
IT1196485B (it) * 1986-07-14 1988-11-16 Zambon Spa Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
CA2004028C (fr) * 1988-12-08 1998-09-22 Motoki Torizuka Derives condenses de benzene
IT1239029B (it) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
DE382180T1 (de) 1991-02-07
DE69009211T2 (de) 1994-10-27
NO900644L (no) 1990-08-13
CA2009709A1 (fr) 1990-08-10
NZ232437A (en) 1991-06-25
ES2017900A4 (es) 1991-03-16
IT1230706B (it) 1991-10-29
HUT58089A (en) 1992-01-28
GR900300167T1 (en) 1991-09-27
ES2017900T3 (es) 1994-08-01
EP0382180B1 (fr) 1994-06-01
DE69009211D1 (de) 1994-07-07
IT8919401A0 (it) 1989-02-10
KR910015574A (ko) 1991-09-30
HU209602B (en) 1994-09-28
AU630661B2 (en) 1992-11-05
NO900644D0 (no) 1990-02-09
AU4927190A (en) 1990-08-16
HU900717D0 (en) 1990-04-28
IE900261L (en) 1990-08-10
IL93197A0 (en) 1990-11-05
FI900665A7 (fi) 1990-08-11
IL93197A (en) 1994-08-26
US5066644A (en) 1991-11-19
FI900665A0 (fi) 1990-02-09
EP0382180A2 (fr) 1990-08-16
EP0382180A3 (en) 1990-11-28
JPH02250896A (ja) 1990-10-08
ATE106407T1 (de) 1994-06-15

Similar Documents

Publication Publication Date Title
AU7586294A (en) Process for the manufacture of suture needles and needles produced thereby
EP0459820A3 (en) Bipolar membrane and method for its production
PL332720A1 (en) Novel derivatives of piperydinketone carboxylic acids, their production and application
PL326081A1 (en) Novel derivatives of amino acids, their production and application
PL329241A1 (en) Novel derivatives of alpha-hydroxycarboxylic acids, their production and application
FI880324A0 (fi) Foerfarande foer framstaellning av 4-tiazolidinkarboxylsyraderivat.
PL329238A1 (en) Novel derivatives of alpha-hydroxycarboxylic acids, their production and application
AU642259B2 (en) Novel 3,3'-dithiobis (propionic acids) and esters thereof
PL329240A1 (en) Novel derivatives of carboxylic acid, their production and application
ZA90645B (en) Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties
HUT54690A (en) Process for producing oxophtalazinyl-acetic acid derivatives and intermediates
DE69321885D1 (de) Verfahren zur fermentativen Herstellung von 10-Hydroxy-C18-Carbonsäure und Gamma-Dodekalaktonderivaten
SG60001A1 (en) Novel microorganism use thereof and process for the production of l-alpha-amino acids
PL325398A1 (en) Novel derivatives of carboxylic acids, their production and application
EP0422470A3 (en) Thiazolcarboxylic acid amide derivatives
PH25252A (en) Novel microorganism and method for production of glutamic acid using the same
AU1706792A (en) Process for the preparation of 3,4,6-trifluorophthalic acid and the anhydride thereof
AU624963B2 (en) Novel cyclic anthranilic acid carboxylic acid derivatives
JPS6450852A (en) Manufacture of l,l or d,d or racemic n6- benzyloxycarbonyl-2,6-diaminopimelamic acid
AU5600590A (en) High lysine producing microorganisms
PL299605A1 (en) Derivatives of aminobenzoic acids substituted with 2-hydroxy-3-methacryl iloxypropyl group
AU4455997A (en) Process for the production of biologically degradable aliphatic polyester amide solutions
HUT55371A (en) Process for producing isoxazole-5-carboxylic acid amide derivatives
AU654513B2 (en) N-aryl-3-aryl-4-substituted-2,3,4,5-tetrahydro-1H-pyrazole-1 -carboxamides and methods of their production
EP0426333A3 (en) Acetic acid derivatives and their production