ZA908563B - Multi-dose inhaler for medicaments in powder form - Google Patents

Multi-dose inhaler for medicaments in powder form

Info

Publication number
ZA908563B
ZA908563B ZA908563A ZA908563A ZA908563B ZA 908563 B ZA908563 B ZA 908563B ZA 908563 A ZA908563 A ZA 908563A ZA 908563 A ZA908563 A ZA 908563A ZA 908563 B ZA908563 B ZA 908563B
Authority
ZA
South Africa
Prior art keywords
unit
powder form
dose
medicament
cup
Prior art date
Application number
ZA908563A
Other languages
English (en)
Inventor
Salvatore Cocozza
Cocozza Salvatore
Original Assignee
Miat Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat Spa filed Critical Miat Spa
Publication of ZA908563B publication Critical patent/ZA908563B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Window Of Vehicle (AREA)
  • Quick-Acting Or Multi-Walled Pipe Joints (AREA)
  • Food-Manufacturing Devices (AREA)
ZA908563A 1989-10-27 1990-10-25 Multi-dose inhaler for medicaments in powder form ZA908563B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02217289A IT1237118B (it) 1989-10-27 1989-10-27 Inalatore multidose per farmaci in polvere.

Publications (1)

Publication Number Publication Date
ZA908563B true ZA908563B (en) 1991-08-28

Family

ID=11192571

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908563A ZA908563B (en) 1989-10-27 1990-10-25 Multi-dose inhaler for medicaments in powder form

Country Status (21)

Country Link
US (1) US5033463A (de)
EP (1) EP0424790B1 (de)
JP (1) JP2515175B2 (de)
KR (1) KR970009719B1 (de)
AT (1) ATE92349T1 (de)
AU (1) AU625927B2 (de)
CA (1) CA2028192C (de)
DE (1) DE69002581T2 (de)
DK (1) DK0424790T3 (de)
ES (1) ES2044365T3 (de)
FI (1) FI100306B (de)
HR (1) HRP931068B1 (de)
IL (1) IL96061A (de)
IT (1) IT1237118B (de)
NO (1) NO176468C (de)
NZ (1) NZ235809A (de)
RU (1) RU1837897C (de)
SI (1) SI9012031A (de)
TR (1) TR24793A (de)
YU (1) YU47804B (de)
ZA (1) ZA908563B (de)

Families Citing this family (227)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
DE4004904A1 (de) * 1990-02-16 1990-09-13 Gerhard Brendel Trommel-applikator
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
YU48707B (sh) * 1990-03-02 1999-07-28 Glaxo Group Limited Aparat za inhaliranje - inhalator
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
AU650953B2 (en) * 1991-03-21 1994-07-07 Novartis Ag Inhaler
BR9106690A (pt) * 1991-04-15 1993-06-29 Huhtamaeki Yhthymae Oy Disposicao para medir uma dose de medicamentos pulverulento para inalacao e aparelho de inalacao dotado do mesmo
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
IT1248059B (it) * 1991-06-14 1995-01-05 Miat Spa Insufflatore multidose per farmaci in polvere
NZ243314A (en) * 1991-06-26 1994-07-26 Schering Corp Powder dispenser; single metered dose rotated to dispensing conduit
WO1993000951A1 (en) * 1991-07-02 1993-01-21 Inhale, Inc. Method and device for delivering aerosolized medicaments
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
HUT64242A (en) * 1991-08-15 1993-12-28 Bon Del Inhalator and method for inhaling
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
EP0826386B1 (de) * 1991-08-26 2003-11-26 Minnesota Mining And Manufacturing Company Pulverspender
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
SE9201411D0 (sv) * 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
US5249424A (en) * 1992-06-05 1993-10-05 Astronautics Corporation Of America Active magnetic regenerator method and apparatus
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
IL106930A0 (en) * 1992-09-08 1993-12-28 Norton Healthcare Ltd Medicament dispensing device
ATE220327T1 (de) 1992-09-29 2002-07-15 Inhale Therapeutic Syst Pulmonale abgabe von aktiven fragmenten des parathormons
DE69322789T2 (de) * 1992-10-19 1999-07-01 Dura Pharmaceuticals, Inc., San Diego, Calif. Trockenpulverinhalator
CA2152088C (en) * 1992-12-18 1999-12-07 Thomas J. Ambrosio Inhaler for powdered medications
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
ES2115923T3 (es) * 1992-12-24 1998-07-01 Rhone Poulenc Rorer Ltd Inhaladores.
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
IL108780A (en) * 1993-02-27 1999-06-20 Fisons Plc Inhalation device
CA2157584C (en) * 1993-03-03 1999-05-04 Paul Mulhauser Dry powder medicament inhalator
EP0652022B1 (de) * 1993-05-12 1999-01-27 Teijin Limited Vorrichtung und verfahren zur dosierten abgabe von pulverförmigen arzneistoffen
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
ES2218543T3 (es) * 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
CN1318104C (zh) 1994-09-21 2007-05-30 耐科塔医药公司 送料管组件
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
SE9404140D0 (sv) * 1994-11-29 1994-11-29 Astra Ab Dose indicating device
SE9404439D0 (sv) * 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5645051A (en) * 1995-04-21 1997-07-08 Dura Pharmaceuticals, Inc. Unit dose dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6357442B1 (en) 1995-06-08 2002-03-19 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIS)
US5826571A (en) * 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
SE504458C2 (sv) * 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
FR2738153B1 (fr) * 1995-09-04 1998-01-02 Valois Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent
DE19533979A1 (de) * 1995-09-14 1997-03-20 Alfred Von Schuckmann Gerät zur dosierten, luftgetragenen Ausgabe von Substanzen
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
ES2216418T3 (es) * 1995-12-07 2004-10-16 Jago Research Ag Boquilla para un inhalador para la administracion de varias dosis de un polvo seco farmacologico.
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
CZ298885B6 (cs) 1996-02-21 2008-03-05 Schering Corporation Inhalátor práškových léku
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700937D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6345617B1 (en) * 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
IT238038Y1 (it) 1997-11-12 2000-09-29 Miat Spa Erogatore multidose di una sostanza in polvere o in grani,del tipo incui l'approntamento di una dose comporta la rotazione di un alberino
US20060213505A1 (en) * 1997-11-14 2006-09-28 Astrazeneca Ab Inhalation device
SE9704185D0 (sv) * 1997-11-14 1997-11-14 Astra Pharma Prod Inhalation device
US7967011B2 (en) * 1997-11-14 2011-06-28 Astrazeneca Ab Inhalation device
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
AU742962B2 (en) * 1998-01-30 2002-01-17 Mibe Gmbh Arzneimittel Inhalation apparatus for powder medications
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
CN1623607B (zh) * 1998-06-12 2011-03-30 微量技术公司 用于从容器输送粉状药物的空气吸入装置
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
ATE294608T1 (de) 1999-06-05 2005-05-15 Innovata Biomed Ltd Verabreichungsystem für medikamente
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
WO2001013891A2 (en) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
AU2001241697A1 (en) * 2000-02-25 2001-10-30 Dura Pharmaceuticals, Inc. Dosing system for a dry powder inhaler
EP1142601B1 (de) * 2000-04-07 2006-02-08 Andi-Ventis Limited Mundstück für eine Vorrichtung zum Inhalieren von Partikeln
WO2001076671A2 (en) 2000-04-11 2001-10-18 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US6948494B1 (en) 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AU2001263098A1 (en) 2000-05-12 2001-11-26 Iep Pharmaceutical Devices, Inc. Powder/liquid metering valve
EP1163920B1 (de) * 2000-06-13 2004-09-01 Andi-Ventis Limited Mundstück für einen Pulverinhalator
PE20020074A1 (es) * 2000-06-23 2002-02-05 Norton Healthcare Ltd Sistema dosificador para inhalador de medicamento
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2001294808A1 (en) * 2000-09-29 2002-04-08 Board Of Trustees Operating Michigan State University Catecholamine pharmaceutical compositions and methods
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
JP2005504715A (ja) * 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ，インコーポレイテッド 持続放出特性を有する吸入用粒子
US6626173B2 (en) 2001-01-08 2003-09-30 Iep Pharmaceutical Devices Inc. Dry powder inhaler
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10129703A1 (de) 2001-06-22 2003-01-02 Sofotec Gmbh & Co Kg Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
WO2003020197A1 (en) * 2001-09-05 2003-03-13 Vectura Limited Improvements in or relating to the delivery of oral drugs
WO2003026559A2 (en) 2001-09-28 2003-04-03 Kurve Technology, Inc Nasal nebulizer
US6779520B2 (en) 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
WO2003043603A1 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
JP4368198B2 (ja) * 2001-11-20 2009-11-18 アルカーメス，インコーポレイテッド 肺送達用の改良された粒状組成物
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US7368102B2 (en) 2001-12-19 2008-05-06 Nektar Therapeutics Pulmonary delivery of aminoglycosides
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US8122881B2 (en) * 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
EP2080561A3 (de) * 2002-08-06 2016-11-16 Glaxo Group Limited Ausgabe
FR2849386B1 (fr) * 2002-12-27 2005-03-18 Bertin Technologies Sa Dispositif d'inhalation de poudre seche
EP1599243B1 (de) * 2003-03-04 2013-12-25 Norton Healthcare Limited Medikamentenspender mit anzeige des zustands eines internen medikamentenreservoirs
EP1488819A1 (de) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Trockenpulverinhalator und Verfahren zur pulmonalen Inhalation von Trockenpulver
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
ITMO20030229A1 (it) * 2003-08-07 2005-02-08 Roberto Oliva Inalatore per preparati in polvere.
FI20031158A7 (fi) * 2003-08-15 2005-02-16 Medifiq Healthcare Oy Inhalaattori
GB0323085D0 (en) 2003-10-02 2003-11-05 Norton Healthcare Ltd Dry powder inhalation apparatus
US7621273B2 (en) * 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
WO2005102429A1 (en) 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
NZ551669A (en) 2004-05-31 2010-07-30 Almirall Lab Combinations comprising antimuscarinic agents and PDE4 inhibitors
NZ563417A (en) 2005-05-18 2012-01-12 Mpex Pharmaceuticals Inc Aerosolized fluoroquinolones and uses thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
WO2007073302A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab New device
JP5188991B2 (ja) * 2006-03-03 2013-04-24 エスティーシー．ユーエヌエム 空力弾性分配メカニズムを有するドライパウダー吸入器
KR101335333B1 (ko) * 2006-06-27 2013-12-03 오오쯔까 테크노 코포레이션 분말흡입기
CA2667225C (en) 2006-10-25 2015-06-09 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
ES2378786T3 (es) * 2006-12-22 2012-04-17 Almirall, S.A. Dispositivo de inhalación para fármacos en forma de polvo
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
WO2009029028A1 (en) * 2007-08-24 2009-03-05 Astrazeneca Ab Breath- triggered inhaler with dose counter
WO2009046215A2 (en) * 2007-10-02 2009-04-09 Lab International Srl Safety and abuse deterrent improved device
EP2058025B1 (de) * 2007-11-09 2014-09-03 Hitachi Ltd. Vorrichtung zur Verabreichung von Pulvermedikation
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
EP2096105A1 (de) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. 4-(2-Amino-1-hydroxyethyl)Phenol-Derivate als Agonisten des b2-adrenergen Rezeptors
EP2100598A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2100599A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2108641A1 (de) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren
EP2113503A1 (de) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
CA2739897C (en) 2008-10-07 2017-10-03 Mpex Pharmaceuticals, Inc. Aerosol fluoroquinolone formulations for improved pharmacokinetics
EP2196465A1 (de) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea-Derivate als PDE4 Hemmern
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
EP2221055A1 (de) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one für die Behandlung von Lungenfunktion
EP2221297A1 (de) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-Difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on und seine Verwendung bei der Behandlung von Atemwegserkrankungen
EP2226323A1 (de) 2009-02-27 2010-09-08 Almirall, S.A. Neuartige Tetrahydropyrazol[3,4-c]isochinolin-5-amin-Derivate
EP2228368A1 (de) 2009-03-12 2010-09-15 Almirall, S.A. Verfahren zur Herstellung von 5-(2-{[6-(2,2-Difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on
NZ620527A (en) * 2009-04-23 2015-08-28 Takeda Gmbh Improved apparatus for the aerosolization of large volumes of dry powder
FR2946537B1 (fr) * 2009-06-11 2012-08-03 Valois Sas Dispositif d'inhalation de poudre
DK2473170T3 (da) 2009-09-04 2019-08-12 Horizon Orphan Llc Anvendelse af aerosoliseret levofloxacin til behandling af cystisk fibrose
EP2322176A1 (de) 2009-11-11 2011-05-18 Almirall, S.A. Neue 7-Phenyl-[1,2,4]triazol[4,3-a]pyridin-3(2H)on-Derivate
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
EP2380890A1 (de) 2010-04-23 2011-10-26 Almirall, S.A. Neue 7,8-Dihydro-1,6-Naphthyridin-5(6H)-on-Derivate als PDE4 Inhibitoren
EP2386555A1 (de) 2010-05-13 2011-11-16 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
EP2394998A1 (de) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl Derivate als PDE4 Inhibitoren
EP2441755A1 (de) 2010-09-30 2012-04-18 Almirall, S.A. Pyridin- und Isochinolin-Derivate als Syk- und JAK-Kinase-Inhibitors
EP2457900A1 (de) 2010-11-25 2012-05-30 Almirall, S.A. Neue Pyrazolderivate mit CRTH2-antagonistischem Verhalten
EP2463289A1 (de) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]Pyridazin-Derivate als AS JAK-Hemmer
JP6050758B2 (ja) 2010-12-07 2016-12-21 レスピラ セラピューティクス インコーポレイテッドＲｅｓｐｉｒａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 乾燥粉末吸入器及びその作動方法
JP5672449B2 (ja) 2011-01-14 2015-02-18 ニプロ株式会社 粉体噴射装置
ES2913095T3 (es) 2011-01-31 2022-05-31 Avalyn Pharma Inc Compuestos de pirfenidona y análogos de piridona en aerosol y usos de los mismos
EP2489663A1 (de) 2011-02-16 2012-08-22 Almirall, S.A. Verbindungen als Syk-Kinasehemmer
EP2510928A1 (de) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten
EP2518070A1 (de) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinonderivate als PI3K-Inhibitoren
EP2518071A1 (de) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridinderivate als PI3K-Inhibitoren
EP2526945A1 (de) 2011-05-25 2012-11-28 Almirall, S.A. Neue CRTH2-Antagonisten
EP2527344A1 (de) 2011-05-25 2012-11-28 Almirall, S.A. Als Medikamente zur Behandlung von myeloproliferativen Krankheiten, Transplantatabstossung, immunbedingten und entzündlichen Erkrankungen geeignete Pyridin-2(1H-)-on-Derivate
EP2548876A1 (de) 2011-07-18 2013-01-23 Almirall, S.A. Neue CRTH2-Antagonisten
EP2548863A1 (de) 2011-07-18 2013-01-23 Almirall, S.A. Neue CRTH2-Antagonisten
EP2554544A1 (de) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1H-)-on-Derivate als JAK-Inhibitoren
EP2578570A1 (de) 2011-10-07 2013-04-10 Almirall, S.A. Neues Verfahren zur Herstellung von 5-(2-{[6-(2,2-Difluor-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxychinolin-2(1H)-on mittels neuen Synthesezwischenstoffen
EP2592078A1 (de) 2011-11-11 2013-05-15 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
EP2592077A1 (de) 2011-11-11 2013-05-15 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP2641900A1 (de) 2012-03-20 2013-09-25 Almirall, S.A. Neuartige polymorphe Kristallformen von 5-(2-{[6-(2,2-difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on, Heminapadisylat als Agonist des beta2-adrenergen Rezeptors
EP2647627A1 (de) 2012-04-02 2013-10-09 Almirall, S.A. Salze von 5-[(1r)-(2-{[4-(2,2-difluor-2-phenylethoxy)phenyl].ethyl}amino}-1- hydroxyethyl)-8-hydroxychinolin-2(1H)-on.
EP2666465A1 (de) 2012-05-25 2013-11-27 Almirall, S.A. Neuartige Dosierung und Formulierung
EP2668941A1 (de) 2012-05-31 2013-12-04 Almirall, S.A. Neue Darreichungsform und Formulierung von Abediterol
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (de) 2012-11-28 2014-06-04 Almirall, S.A. Neue bizyklische Verbindungen als CRAC-Kanalmodulatoren
AU2013360866A1 (en) 2012-12-18 2015-07-02 Almirall, S.A. New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activity
UY35332A (es) 2013-02-15 2014-11-28 Almirall Sa Derivados de pirrolotriazina como inhibidores de pi3k
US8920364B2 (en) 2013-02-28 2014-12-30 Medtronic Xomed, Inc. Biomaterial delivery device
US8845578B2 (en) 2013-02-28 2014-09-30 Medtronic Xomed, Inc. Biomaterial delivery device
EP2848615A1 (de) 2013-07-03 2015-03-18 Almirall, S.A. Neue Pyrazolderivate als CRAC-Kanalmodulatoren
JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク． エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
WO2015091287A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
EP4491180A1 (de) 2014-01-10 2025-01-15 Avalyn Pharma Inc. Aerosol-pirfenidon- und pyridonanalogverbindungen und verwendungen davon
CN107427650A (zh) 2015-01-14 2017-12-01 瑞必治公司 粉末分散方法和装置
MA41938A (fr) 2015-04-21 2018-02-28 Almirall Sa Dérivés hétérocycliques amino-substitués utilisés comme inhibiteurs des canaux sodiques
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
KR20190014288A (ko) 2017-08-01 2019-02-12 주식회사 디에이피 수직형 로더 제어 방법
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
WO2019173846A1 (en) * 2018-03-09 2019-09-12 Health Research, Inc. Induction spacer for inhaler
JP2023514893A (ja) * 2019-05-24 2023-04-12 ピュア サイエンティフィック テクノロジーズ インコーポレイテッド 二重計測吸入器
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3027897A (en) * 1959-07-23 1962-04-03 Carofiglio Louis Edward Nasal inhaler
FR2224175B1 (de) * 1973-04-04 1978-04-14 Isf Spa
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2926659A1 (de) * 1979-07-02 1981-01-15 Kaiser Richard Schnupfgeraet
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
ATE23272T1 (de) * 1981-07-08 1986-11-15 Draco Ab Pulverinhalator.
US4570630A (en) * 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli

Also Published As

Publication number Publication date
YU47804B (sr) 1996-01-09
NZ235809A (en) 1993-04-28
NO904661L (no) 1991-04-29
ATE92349T1 (de) 1993-08-15
US5033463A (en) 1991-07-23
JPH03184563A (ja) 1991-08-12
EP0424790A3 (en) 1991-11-21
ES2044365T3 (es) 1994-01-01
IT8922172A0 (it) 1989-10-27
IT1237118B (it) 1993-05-18
FI100306B (fi) 1997-11-14
KR970009719B1 (ko) 1997-06-17
DE69002581D1 (de) 1993-09-09
AU625927B2 (en) 1992-07-16
DK0424790T3 (da) 1993-12-13
HRP931068A2 (en) 1995-02-28
NO904661D0 (no) 1990-10-26
AU6498790A (en) 1991-05-02
FI905163A0 (fi) 1990-10-19
NO176468C (no) 1995-04-12
NO176468B (no) 1995-01-02
IL96061A0 (en) 1991-07-18
TR24793A (tr) 1992-05-01
CA2028192C (en) 1995-01-10
CA2028192A1 (en) 1991-04-28
IT8922172A1 (it) 1991-04-27
YU203190A (sh) 1994-04-05
HRP931068B1 (en) 1998-02-28
JP2515175B2 (ja) 1996-07-10
SI9012031A (en) 1997-10-31
EP0424790B1 (de) 1993-08-04
RU1837897C (ru) 1993-08-30
DE69002581T2 (de) 1993-11-25
EP0424790A2 (de) 1991-05-02
IL96061A (en) 1994-08-26
KR910007553A (ko) 1991-05-30

Similar Documents

Publication Publication Date Title
EP0424790A3 (en) Multi-dose inhaler for medicaments in powder form
CA2070297A1 (en) Multi-dose insufflator for medicaments in powder form
ATE103825T1 (de) Inhalationsvorrichtung zur mehrfachen ausgabe von einzeldosen pulverfoermiger arzneimittel.
ES2060040T3 (es) Dispositivo y formulacion de inhalacion de medicamento.
PL334199A1 (en) Method of meteringly dispensing and packaging drugs
IL81368A0 (en) Medical dosing device for discharge of atomized medicament for inhalation air
EP0640354A2 (de) Wirbelkammer-Pulverinhalator
TW325409B (en) Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
HK67589A (en) Devices for administering medicaments to patients
ATE79284T1 (de) Zur vollstaendigen entleerung der kapsel geeigneter inhalator.
IE40616B1 (en) Apparatus for dispensing dosages of powdered medicaments by inhalation
ZA87409B (en) Medical dosing device for discharge of atomized medicament for inhalation air
PT84193B (en) Medical dosing device for discharge of atomized medicament for inhalation air