ZA911537B - Milbemycin ether derivatives,their preparation and their anthelmintic uses - Google Patents

Milbemycin ether derivatives,their preparation and their anthelmintic uses

Info

Publication number: ZA911537B
Authority: ZA; South Africa
Prior art keywords: chr; hydrogen; alkyl; anthelmintic; chem
Prior art date: 1990-03-01

Application number

ZA911537A

Other languages

English (en)

Inventor

Yasuhiro Morisawa

Morisawa Yasuhiro

Akio Saito

Saito Akio

Toshimitsu Toyama

Toyama Toshimitsu

Susumu Kaneko

Kaneko Susumu

Satoru Naito

Naito Satoru

Louis-Pierre Molleyres

Molleyres Louis-Pierre

Jean-Claude Gehret

Gehret Jean-Claude

Original Assignee

Sankyo Co

Ciba Geigy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-01

Filing date

1991-03-01

Publication date

1991-12-24

1991-03-01 Application filed by Sankyo Co, Ciba Geigy filed Critical Sankyo Co

1991-12-24 Publication of ZA911537B publication Critical patent/ZA911537B/xx

Links

230000000507 anthelmentic effect Effects 0.000 title abstract 2
150000002170 ethers Chemical class 0.000 title 1
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000000749 insecticidal effect Effects 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000000962 organic group Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Dentistry (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Agronomy & Crop Science (AREA)
Pest Control & Pesticides (AREA)
Plant Pathology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

ZA911537A 1990-03-01 1991-03-01 Milbemycin ether derivatives,their preparation and their anthelmintic uses ZA911537B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP5076190		1990-03-01

Publications (1)

Publication Number	Publication Date
ZA911537B true ZA911537B (en)	1991-12-24

Family

ID=12867818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA911537A ZA911537B (en)	1990-03-01	1991-03-01	Milbemycin ether derivatives,their preparation and their anthelmintic uses

Country Status (11)

Country	Link
EP (1)	EP0444964B1 (de)
JP (1)	JPH085894B2 (de)
KR (1)	KR0161533B1 (de)
AT (1)	ATE113285T1 (de)
AU (1)	AU640456B2 (de)
CA (1)	CA2037411C (de)
DE (1)	DE69104746T2 (de)
DK (1)	DK0444964T3 (de)
ES (1)	ES2066345T3 (de)
NZ (1)	NZ237275A (de)
ZA (1)	ZA911537B (de)

Families Citing this family (169)

* Cited by examiner, † Cited by third party
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TW202452B (de) *	1989-12-01	1993-03-21	Ciba Geigy Ag
US5276033A (en) *	1991-12-18	1994-01-04	Sankyo Company, Limited	13-(substituted thio)acetoxymilbemycin derivatives, their preparation and their agrochemical uses
TW262474B (de) *	1992-09-01	1995-11-11	Sankyo Co
US5614470A (en) *	1994-04-01	1997-03-25	Sankyo Company, Limited	13-substituted milbemycin derivatives, their preparation and their use
WO1996016064A1 (en) *	1994-11-24	1996-05-30	Sankyo Company, Limited	13-etherified milbemycin derivative with insecticidal activity
US6221894B1 (en)	1995-03-20	2001-04-24	Merck & Co., Inc.	Nodulisporic acid derivatives
AU9785698A (en)	1997-10-02	1999-04-27	Microcide Pharmaceuticals, Inc.	Fungal efflux pump inhibitors
US6136838A (en) *	1998-03-19	2000-10-24	Merck & Co., Inc.	Sulfurpentafluorophenylpyrazoles for controlling ectoparasitic infestations
EP1735284A1 (de)	2004-03-18	2006-12-27	Pfizer Limited	N-(1-arylpyrazol-4l)sulfonamide und deren verwendung als parasitizide
US7919522B2 (en)	2007-05-03	2011-04-05	Merial Limited	Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds
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1990
- 1990-11-30 JP JP2336728A patent/JPH085894B2/ja not_active Expired - Fee Related
1991
- 1991-02-28 KR KR1019910003394A patent/KR0161533B1/ko not_active Expired - Fee Related
- 1991-03-01 ZA ZA911537A patent/ZA911537B/xx unknown
- 1991-03-01 ES ES91301748T patent/ES2066345T3/es not_active Expired - Lifetime
- 1991-03-01 CA CA002037411A patent/CA2037411C/en not_active Expired - Lifetime
- 1991-03-01 AU AU71999/91A patent/AU640456B2/en not_active Ceased
- 1991-03-01 DK DK91301748.9T patent/DK0444964T3/da active
- 1991-03-01 NZ NZ237275A patent/NZ237275A/en unknown
- 1991-03-01 DE DE69104746T patent/DE69104746T2/de not_active Expired - Fee Related
- 1991-03-01 EP EP91301748A patent/EP0444964B1/de not_active Expired - Lifetime
- 1991-03-01 AT AT91301748T patent/ATE113285T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR0161533B1 (ko)	1998-12-01
DE69104746T2 (de)	1995-06-14
DE69104746D1 (de)	1994-12-01
AU7199991A (en)	1991-09-05
ES2066345T3 (es)	1995-03-01
AU640456B2 (en)	1993-08-26
EP0444964A1 (de)	1991-09-04
DK0444964T3 (da)	1995-02-27
CA2037411A1 (en)	1991-09-02
NZ237275A (en)	1993-04-28
JPH085894B2 (ja)	1996-01-24
HK1006310A1 (en)	1999-02-19
EP0444964B1 (de)	1994-10-26
ATE113285T1 (de)	1994-11-15
KR910016756A (ko)	1991-11-05
JPH04305579A (ja)	1992-10-28
CA2037411C (en)	2001-10-23

Publication	Publication Date	Title
ZA911537B (en)	1991-12-24	Milbemycin ether derivatives,their preparation and their anthelmintic uses
AU4092489A (en)	1990-03-08	13-substituted milbemycin derivatives, their preparation and use
HUT52562A (en)	1990-07-28	Insecticides and miticides containing as active substance derivatives of macrolide
ES8802229A1 (es)	1988-04-16	Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
ES2099604T3 (es)	1997-05-16	Nuevos compuestos a83543 y procedimiento para su produccion.
JPS6479184A (en)	1989-03-24	Pyrazolotriazine derivative
CA2146047A1 (en)	1995-10-02	13-substituted milbemycin derivatives, their preparation and use
IE890259L (en)	1989-08-28	Macrolide compounds
AU6235790A (en)	1991-03-14	13-alkyl-23-imino and 13-halo-23-imino derivatives of ll-f28249 compounds and their use as endo- and ecto-parasiticidal, insecticidal, acaricidal and nematocidal agents
AU2208888A (en)	1989-03-16	Macrolide compounds
DE3880088D1 (de)	1993-05-13	Ethylierte avermectine.
EP0332580A3 (de)	1991-01-16	Von Milbemycinen ableitbare Insektizide und Parasitizide
ES2053034T3 (es)	1994-07-16	Un procedimiento para la preparacion de butalactina y su empleo como producto farmaceutico.