ZA918115B - Hydroxyalkylquinoline ether acids as leukotriene antagonists - Google Patents
Hydroxyalkylquinoline ether acids as leukotriene antagonistsInfo
- Publication number
- ZA918115B ZA918115B ZA918115A ZA918115A ZA918115B ZA 918115 B ZA918115 B ZA 918115B ZA 918115 A ZA918115 A ZA 918115A ZA 918115 A ZA918115 A ZA 918115A ZA 918115 B ZA918115 B ZA 918115B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxyalkylquinoline
- leukotriene antagonists
- ether acids
- compounds
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59688590A | 1990-10-12 | 1990-10-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA918115B true ZA918115B (en) | 1992-08-26 |
Family
ID=24389130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA918115A ZA918115B (en) | 1990-10-12 | 1991-10-11 | Hydroxyalkylquinoline ether acids as leukotriene antagonists |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0480708B1 (cs) |
| JP (1) | JP2538154B2 (cs) |
| KR (1) | KR920008005A (cs) |
| CN (1) | CN1061594A (cs) |
| AT (1) | ATE128969T1 (cs) |
| AU (1) | AU639612B2 (cs) |
| CA (1) | CA2053208C (cs) |
| CS (1) | CS309491A3 (cs) |
| DE (1) | DE69113735T2 (cs) |
| ES (1) | ES2079586T3 (cs) |
| FI (1) | FI914795L (cs) |
| HU (1) | HUT61982A (cs) |
| IE (1) | IE913610A1 (cs) |
| IL (1) | IL99683A0 (cs) |
| MX (1) | MX9101556A (cs) |
| NO (1) | NO914003L (cs) |
| PT (1) | PT99211B (cs) |
| ZA (1) | ZA918115B (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5506227A (en) * | 1992-04-13 | 1996-04-09 | Merck Frosst Canada, Inc. | Pyridine-substituted benzyl alcohols as leukotriene antagonists |
| US5358955A (en) * | 1992-10-30 | 1994-10-25 | Abbott Laboratories | Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosynthesis |
| US5438141A (en) * | 1993-05-21 | 1995-08-01 | Merck Frosst Canada, Inc. | Heteroaryl and haloaryl quinoline derivatives of cyclopropaneacetic acid as leukotriene antagonists |
| JPH09278653A (ja) * | 1996-04-05 | 1997-10-28 | Santen Pharmaceut Co Ltd | 網膜疾患治療剤 |
| WO1998008820A1 (en) * | 1996-08-26 | 1998-03-05 | Yamanouchi Pharmaceutical Co., Ltd. | Benzenesulfone compounds and salts thereof |
| GB2356139A (en) * | 1999-11-15 | 2001-05-16 | Bayer Ag | Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides for the treatment of diseases |
| EP1958936A1 (en) * | 2007-02-14 | 2008-08-20 | Inke, S.A. | Process for obtaining montelukast |
| CA2842881A1 (en) * | 2011-07-26 | 2013-04-11 | Rajendrasinh RATHOD | Cysteinyl leukotriene antagonists |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62120365A (ja) * | 1985-11-16 | 1987-06-01 | バイエル・アクチエンゲゼルシヤフト | 置換ベンジルエ−テル類、その製造法および用途 |
| IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
| JPS62258369A (ja) * | 1986-05-02 | 1987-11-10 | Nippon Soda Co Ltd | キナゾリノン誘導体及びその製造方法 |
| EP0271287A3 (en) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Quinoline dioic acids and amides |
| IL88433A0 (en) * | 1987-11-25 | 1989-06-30 | Merck Frosst Canada Inc | Diarylstyrylquinoline diacids and pharmaceutical compositions containing them |
| EP0349062A1 (en) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Quinoline ether alkanoic acid |
| NZ233752A (en) * | 1989-05-24 | 1993-05-26 | Merck Frosst Canada Inc | Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof |
-
1991
- 1991-10-09 DE DE69113735T patent/DE69113735T2/de not_active Expired - Fee Related
- 1991-10-09 IL IL99683A patent/IL99683A0/xx unknown
- 1991-10-09 ES ES91309289T patent/ES2079586T3/es not_active Expired - Lifetime
- 1991-10-09 EP EP91309289A patent/EP0480708B1/en not_active Expired - Lifetime
- 1991-10-09 AT AT91309289T patent/ATE128969T1/de not_active IP Right Cessation
- 1991-10-10 HU HU913218A patent/HUT61982A/hu unknown
- 1991-10-10 CA CA002053208A patent/CA2053208C/en not_active Expired - Fee Related
- 1991-10-11 NO NO91914003A patent/NO914003L/no unknown
- 1991-10-11 ZA ZA918115A patent/ZA918115B/xx unknown
- 1991-10-11 CS CS913094A patent/CS309491A3/cs unknown
- 1991-10-11 CN CN91111074A patent/CN1061594A/zh active Pending
- 1991-10-11 FI FI914795A patent/FI914795L/fi not_active Application Discontinuation
- 1991-10-11 PT PT99211A patent/PT99211B/pt not_active IP Right Cessation
- 1991-10-11 AU AU85797/91A patent/AU639612B2/en not_active Ceased
- 1991-10-11 MX MX9101556A patent/MX9101556A/es unknown
- 1991-10-12 KR KR1019910017952A patent/KR920008005A/ko not_active Withdrawn
- 1991-10-14 JP JP3331108A patent/JP2538154B2/ja not_active Expired - Lifetime
- 1991-10-16 IE IE361091A patent/IE913610A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0480708A3 (en) | 1992-05-20 |
| IE913610A1 (en) | 1992-04-22 |
| CN1061594A (zh) | 1992-06-03 |
| HUT61982A (en) | 1993-03-29 |
| PT99211A (pt) | 1992-09-30 |
| NO914003L (no) | 1992-04-13 |
| AU639612B2 (en) | 1993-07-29 |
| NO914003D0 (no) | 1991-10-11 |
| JP2538154B2 (ja) | 1996-09-25 |
| HU913218D0 (en) | 1992-01-28 |
| AU8579791A (en) | 1992-04-16 |
| EP0480708B1 (en) | 1995-10-11 |
| FI914795A7 (fi) | 1992-04-13 |
| MX9101556A (es) | 1994-01-31 |
| DE69113735D1 (de) | 1995-11-16 |
| JPH05105664A (ja) | 1993-04-27 |
| FI914795L (fi) | 1992-04-13 |
| ES2079586T3 (es) | 1996-01-16 |
| PT99211B (pt) | 1999-04-30 |
| IL99683A0 (en) | 1992-08-18 |
| CS309491A3 (en) | 1992-04-15 |
| KR920008005A (ko) | 1992-05-27 |
| DE69113735T2 (de) | 1996-06-13 |
| CA2053208A1 (en) | 1992-04-13 |
| FI914795A0 (fi) | 1991-10-11 |
| CA2053208C (en) | 2003-04-15 |
| EP0480708A2 (en) | 1992-04-15 |
| ATE128969T1 (de) | 1995-10-15 |
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| CY2094B1 (en) | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | |
| ZA932533B (en) | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | |
| FI920734A0 (fi) | Ketosyror innehaollande kinoliner med leukotrienantagonisteffekt. | |
| PL309408A1 (en) | Diaryl-5,6-condensed heterocyclic acids as leucotrenic antagonistic substances | |
| EP0480708A3 (en) | Hydroxyalkylquinoline ether acids as leukotriene antagonists | |
| MY107767A (en) | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |