ZA923962B - Nucleoside derivative - Google Patents

Nucleoside derivative

Info

Publication number: ZA923962B
Authority: ZA; South Africa
Prior art keywords: pct; sec; date; nucleoside derivative; pub
Prior art date: 1991-05-30

Application number

ZA923962A

Other languages

English (en)

Inventor

Richard Wilson Peck

John Posner

Kenneth Powell

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-05-30

Filing date

1992-05-29

Publication date

1993-11-29

1992-05-29 Application filed by Wellcome Found filed Critical Wellcome Found

1993-11-29 Publication of ZA923962B publication Critical patent/ZA923962B/xx

Links

150000003833 nucleoside derivatives Chemical class 0.000 title 1
QLOCVMVCRJOTTM-SDNRWEOFSA-N 1-[(2r,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione Chemical compound O=C1NC(=O)C(C#CC)=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 QLOCVMVCRJOTTM-SDNRWEOFSA-N 0.000 abstract 1
108010028554 LDL Cholesterol Proteins 0.000 abstract 1
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

ZA923962A 1991-05-30 1992-05-29 Nucleoside derivative ZA923962B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919111580A GB9111580D0 (en)	1991-05-30	1991-05-30	Nucleoside derivative

Publications (1)

Publication Number	Publication Date
ZA923962B true ZA923962B (en)	1993-11-29

Family

ID=10695778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA923962A ZA923962B (en)	1991-05-30	1992-05-29	Nucleoside derivative

Country Status (14)

Country	Link
US (1)	US5432166A (ja)
EP (1)	EP0542952B1 (ja)
JP (1)	JPH06500129A (ja)
AT (1)	ATE142501T1 (ja)
AU (1)	AU657756B2 (ja)
CA (1)	CA2088264A1 (ja)
DE (1)	DE69213660D1 (ja)
GB (1)	GB9111580D0 (ja)
HU (1)	HUT63767A (ja)
IE (1)	IE921731A1 (ja)
IL (1)	IL102058A (ja)
MX (1)	MX9202595A (ja)
WO (1)	WO1992021352A1 (ja)
ZA (1)	ZA923962B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6753006B1 (en)	1993-02-22	2004-06-22	American Bioscience, Inc.	Paclitaxel-containing formulations
US20030054042A1 (en) *	2001-09-14	2003-03-20	Elaine Liversidge	Stabilization of chemical compounds using nanoparticulate formulations
WO2003080027A1 (en) *	2002-03-20	2003-10-02	Elan Pharma International, Ltd.	Nanoparticulate compositions of angiogenesis inhibitors
SG10201913554YA (en)	2011-12-22	2020-03-30	Alios Biopharma Inc	Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en)	2012-03-21	2016-09-13	Alios Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en)	2012-03-21	2020-08-25	Janssen Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2244328A1 (de) *	1972-09-09	1974-03-21	Boehringer Mannheim Gmbh	Neue n(6)-disubstituierte adenosinderivate und verfahren zur herstellung derselben
US4594339A (en) *	1982-04-06	1986-06-10	Sloan-Kettering Institute For Cancer Research	Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides
IT1196261B (it) *	1984-09-20	1988-11-16	Pierrel Spa	Derivati nucleosidici e purinici 8-sostituiti
US5063233A (en) *	1986-11-14	1991-11-05	Ciba-Geigy Corporation	N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
GB8629892D0 (en) *	1986-12-15	1987-01-28	Wellcome Found	Antiviral compounds
HU198950B (en) *	1986-12-15	1989-12-28	Sandoz Ag	Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
EP0277917A3 (en) *	1987-02-04	1990-03-28	Ciba-Geigy Ag	Certain adenosine 5'-carboxamide derivatives
US4962194A (en) *	1987-04-02	1990-10-09	Warner-Lambert Company	Method of preparing 51,N6-disubstituted adenosines from inosines
US5028596A (en) *	1987-12-14	1991-07-02	Burroughs Wellcome Co.	1-(β-D-arabinofuranosyl)-5-propynyluracil for treatment of VZV infections
GB8729994D0 (en) *	1987-12-23	1988-02-03	Glaxo Group Ltd	Chemical compounds
AU3820989A (en) *	1988-08-02	1990-02-08	Ciba-Geigy Ag	7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives
GB2226027B (en) *	1988-12-13	1992-05-20	Sandoz Ltd	Adenosine derivatives,their production and use
JPH03287537A (ja) *	1990-03-31	1991-12-18	Yamasa Shoyu Co Ltd	抗動脈硬化症剤
FR2665362B1 (fr) *	1990-08-03	1994-12-09	Cepbepe	Substance contenant, comme principe actif, une adenosine substitutee en n6 et son application.

1991
- 1991-05-30 GB GB919111580A patent/GB9111580D0/en active Pending
1992
- 1992-05-29 JP JP4509647A patent/JPH06500129A/ja active Pending
- 1992-05-29 DE DE69213660T patent/DE69213660D1/de not_active Expired - Lifetime
- 1992-05-29 IL IL10205892A patent/IL102058A/en active IP Right Grant
- 1992-05-29 ZA ZA923962A patent/ZA923962B/xx unknown
- 1992-05-29 MX MX9202595A patent/MX9202595A/es unknown
- 1992-05-29 EP EP92910638A patent/EP0542952B1/en not_active Expired - Lifetime
- 1992-05-29 AU AU17673/92A patent/AU657756B2/en not_active Ceased
- 1992-05-29 US US07/988,122 patent/US5432166A/en not_active Expired - Fee Related
- 1992-05-29 WO PCT/GB1992/000971 patent/WO1992021352A1/en not_active Ceased
- 1992-05-29 HU HU9300243A patent/HUT63767A/hu unknown
- 1992-05-29 CA CA002088264A patent/CA2088264A1/en not_active Abandoned
- 1992-05-29 AT AT92910638T patent/ATE142501T1/de not_active IP Right Cessation
- 1992-07-01 IE IE173192A patent/IE921731A1/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU657756B2 (en)	1995-03-23
IL102058A (en)	1996-07-23
JPH06500129A (ja)	1994-01-06
WO1992021352A1 (en)	1992-12-10
IE921731A1 (en)	1992-12-02
EP0542952A1 (en)	1993-05-26
GB9111580D0 (en)	1991-07-24
CA2088264A1 (en)	1992-12-01
HU9300243D0 (en)	1993-04-28
EP0542952B1 (en)	1996-09-11
MX9202595A (es)	1992-11-01
DE69213660D1 (de)	1996-10-17
HUT63767A (en)	1993-10-28
IL102058A0 (en)	1992-12-30
ATE142501T1 (de)	1996-09-15
US5432166A (en)	1995-07-11
AU1767392A (en)	1993-01-08

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