ZA925852B - (-) and (+) 10-(1-azabicyclo(2.2.2.)oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation. - Google Patents

(-) and (+) 10-(1-azabicyclo(2.2.2.)oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation.

Info

Publication number
ZA925852B
ZA925852B ZA925852A ZA925852A ZA925852B ZA 925852 B ZA925852 B ZA 925852B ZA 925852 A ZA925852 A ZA 925852A ZA 925852 A ZA925852 A ZA 925852A ZA 925852 B ZA925852 B ZA 925852B
Authority
ZA
South Africa
Prior art keywords
azabicyclo
phenothiazine
oct
methyl
preparation
Prior art date
Application number
ZA925852A
Other languages
English (en)
Inventor
Raffaello Giorgi
Luigi Turbanti
Alessandro Subissi
Original Assignee
Guidotti & C Spa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guidotti & C Spa Labor filed Critical Guidotti & C Spa Labor
Publication of ZA925852B publication Critical patent/ZA925852B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA925852A 1991-08-07 1992-08-04 (-) and (+) 10-(1-azabicyclo(2.2.2.)oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation. ZA925852B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912225A IT1251161B (it) 1991-08-07 1991-08-07 Derivati ammonio quaternari di (-) e (+)-3-(10 h-fenotiazin-10-ilmetil)-l-azabiciclo (2.2.2.)ottano e composizioni farmaceutiche che li contengono

Publications (1)

Publication Number Publication Date
ZA925852B true ZA925852B (en) 1993-03-05

Family

ID=11360550

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925852A ZA925852B (en) 1991-08-07 1992-08-04 (-) and (+) 10-(1-azabicyclo(2.2.2.)oct-3-yl-methyl)-10 h-phenothiazine quaternary ammonium derivatives, pharmaceutical compositions containing them and process for their preparation.

Country Status (19)

Country Link
EP (1) EP0599896A1 (cs)
JP (1) JPH06509570A (cs)
CN (1) CN1071667A (cs)
AU (1) AU2417392A (cs)
BG (1) BG98439A (cs)
BR (1) BR9206339A (cs)
CA (1) CA2114844A1 (cs)
CZ (1) CZ24894A3 (cs)
EC (1) ECSP920859A (cs)
FI (1) FI940530A7 (cs)
HU (1) HUT66570A (cs)
IT (1) IT1251161B (cs)
MA (1) MA22611A1 (cs)
MX (1) MX9204539A (cs)
PT (1) PT100765A (cs)
SK (1) SK11594A3 (cs)
TN (1) TNSN92073A1 (cs)
WO (1) WO1993003029A1 (cs)
ZA (1) ZA925852B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6072113A (en) * 1996-10-18 2000-06-06 Yamaha Corporation Musical performance teaching system and method, and machine readable medium containing program therefor
WO2003105811A2 (en) * 2002-01-31 2003-12-24 Southwest Research Institute Controlled release compositions and methods for using same
FR2910814B1 (fr) * 2006-12-28 2011-06-17 Pf Medicament Utilisation du 10-°(r3)-1-azabicyclo°2.2.2!oct-3-ylmethyl!-10h- phenothiazine pour la preparation d'un medicament exercant une inhibition selective des recepteurs muscariniques m1,2,3
FR2911606B1 (fr) * 2007-01-18 2009-04-17 Pierre Fabre Medicament Sa Nouveau derive de la quinuclidine utile dans la preparation de la mequitazine
FR2924344B1 (fr) * 2007-12-04 2010-04-16 Pf Medicament Utilisation de la mequitazine sous la forme de racemate ou d'enantiomeres pour la preparation d'un medicament destine au traitement ou a la prevention de pathologies impliquant les recepteurs histaminiques h4.
FR2970255B1 (fr) 2011-01-10 2013-09-06 Pf Medicament Vinyl quinuclidine utile en tant qu'intermediaire de synthese dans la preparation de la (r)-mequitazine.
JP7599646B2 (ja) * 2020-10-29 2024-12-16 国立大学法人金沢大学 薬物代謝酵素活性を測定するための放射性フッ素標識画像診断薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522660A1 (fr) * 1982-03-05 1983-09-09 Pharmuka Lab Isomere levogyre de la mequitazine, son procede de preparation et medicaments le contenant
FR2526433B1 (fr) * 1982-05-04 1985-10-18 Pharmuka Lab Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant
IT1173445B (it) * 1984-03-16 1987-06-24 Guidotti & C Spa Labor Agenti ad attivita' antibroncospastica e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
IT1251161B (it) 1995-05-04
CA2114844A1 (en) 1993-02-18
WO1993003029A1 (en) 1993-02-18
CZ24894A3 (en) 1994-07-13
FI940530L (fi) 1994-02-04
FI940530A0 (fi) 1994-02-04
TNSN92073A1 (fr) 1993-06-08
JPH06509570A (ja) 1994-10-27
MX9204539A (es) 1993-02-01
CN1071667A (zh) 1993-05-05
ITMI912225A0 (it) 1991-08-07
PT100765A (pt) 1993-10-29
EP0599896A1 (en) 1994-06-08
BR9206339A (pt) 1994-11-08
MA22611A1 (fr) 1993-04-01
BG98439A (bg) 1994-09-30
HUT66570A (en) 1994-12-28
AU2417392A (en) 1993-03-02
ITMI912225A1 (it) 1993-02-07
SK11594A3 (en) 1994-12-07
ECSP920859A (es) 1993-08-03
FI940530A7 (fi) 1994-02-04
HU9400273D0 (en) 1994-05-30

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