ZA926837B - A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist - Google Patents
A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonistInfo
- Publication number
- ZA926837B ZA926837B ZA926837A ZA926837A ZA926837B ZA 926837 B ZA926837 B ZA 926837B ZA 926837 A ZA926837 A ZA 926837A ZA 926837 A ZA926837 A ZA 926837A ZA 926837 B ZA926837 B ZA 926837B
- Authority
- ZA
- South Africa
- Prior art keywords
- combination
- pharmaceutical composition
- uricosuric agent
- eaa antagonist
- antagonist
- Prior art date
Links
- 229940116731 Uricosuric agent Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003383 uricosuric agent Substances 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 239000003194 amino acid receptor blocking agent Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- DBABZHXKTCFAPX-UHFFFAOYSA-N probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 abstract 1
- 229960003081 probenecid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75640191A | 1991-09-09 | 1991-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA926837B true ZA926837B (en) | 1994-03-08 |
Family
ID=25043303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA926837A ZA926837B (en) | 1991-09-09 | 1992-09-08 | A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US5407935A (da) |
| EP (1) | EP0603301B1 (da) |
| JP (1) | JP3218038B2 (da) |
| AT (1) | ATE162075T1 (da) |
| AU (1) | AU660717B2 (da) |
| CA (1) | CA2115442C (da) |
| DE (1) | DE69224069T2 (da) |
| DK (1) | DK0603301T3 (da) |
| ES (1) | ES2113957T3 (da) |
| GR (1) | GR3026369T3 (da) |
| MX (1) | MX9205127A (da) |
| NO (1) | NO307645B1 (da) |
| NZ (1) | NZ244243A (da) |
| PT (1) | PT100850B (da) |
| WO (1) | WO1993004688A1 (da) |
| ZA (1) | ZA926837B (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2115442C (en) * | 1991-09-09 | 2003-09-23 | Christopher Franklin Bigge | Pharmaceutical preparation containing an uricosuric agent and an excitatory amino acid antagonist |
| US5318985A (en) * | 1991-12-20 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Potentiation of NMDA antagonists |
| US5854217A (en) | 1992-09-28 | 1998-12-29 | Bearsden Bio, Inc. | Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function |
| JPH07505908A (ja) * | 1992-09-28 | 1995-06-29 | マックセチーニ、マリア ルイザ | Nmda受容体のアロステリックモジュレーター |
| AU735389B2 (en) | 1996-07-22 | 2001-07-05 | Cognetix, Inc. | Use of conantokins |
| EP0956292A4 (en) | 1996-07-22 | 2003-07-30 | Univ Utah Res Found | CONANTOKINES |
| US6277825B1 (en) | 1996-07-22 | 2001-08-21 | University Of Utah Research Foundation | Use of conantokins for treating pain |
| IL125950A0 (en) * | 1997-09-05 | 1999-04-11 | Pfizer Prod Inc | Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy |
| WO1999061008A2 (en) * | 1998-05-26 | 1999-12-02 | Peter Louis Carlen | Compositions and methods for alleviating impaired mental function, memory loss and reducing recovery time in anaesthetized mammals |
| US6399574B1 (en) | 2000-03-22 | 2002-06-04 | University Of Utah Research Foundation | Use of conantokins |
| EP1317258B1 (en) | 2000-06-28 | 2009-02-11 | Merck & Co., Inc. | Use of allopurinol for the treatment of hypertension |
| US7276514B2 (en) * | 2002-05-15 | 2007-10-02 | Charitable Leadership Foundation - Medical Technology Acceleration Program | Pyrroloquinoline quinone drugs for treatment of cardiac injury and methods of use thereof |
| US20080051428A1 (en) * | 2002-05-15 | 2008-02-28 | Davis Paul J | Pyrroloquinoline quinone drugs and methods of use thereof |
| US20040152694A1 (en) * | 2003-02-04 | 2004-08-05 | Istvan Kurucz | Methods and compositions for treating inflammatory disorders of the airways |
| CA2609972C (en) * | 2004-03-22 | 2013-05-14 | Apkarian Technologies Llc | Method and compositions for treatment of chronic neuropathic pain |
| US8461223B2 (en) * | 2005-04-07 | 2013-06-11 | Aspen Aerogels, Inc. | Microporous polycyclopentadiene-based aerogels |
| ITFI20050083A1 (it) * | 2005-04-29 | 2006-10-30 | Univ Firenze | Uso dell'acido chinurenico per la prevenzione e il trattamento dello shock |
| CA2607953A1 (en) | 2005-05-09 | 2006-11-16 | Tap Pharmaceutical Products, Inc. | Methods for treating nephrolithiasis |
| US9181486B2 (en) | 2006-05-25 | 2015-11-10 | Aspen Aerogels, Inc. | Aerogel compositions with enhanced performance |
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| AU2011299153B2 (en) | 2010-09-10 | 2014-10-30 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for concomitant treatment of theophylline and febuxostat |
| US10806711B2 (en) | 2011-08-12 | 2020-10-20 | University Of Cincinnati | Method of treating acute decompensated heart failure with probenecid |
| AU2014244053B2 (en) | 2013-03-13 | 2018-08-30 | University Of Cincinnati | Treatment of a diastolic cardiac dysfunction with a TRPV2 receptor agonist |
| US20170143681A1 (en) | 2015-11-02 | 2017-05-25 | Apkarian Technologies Llc | Methods and compositions for treating pain |
| EP3427729A1 (en) * | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4812458A (en) * | 1986-09-16 | 1989-03-14 | A/S Ferrosan | 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics |
| DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DK0501378T3 (da) * | 1991-02-28 | 1995-03-20 | Merrell Dow Pharma | NMDA-antagonister |
| CA2115442C (en) * | 1991-09-09 | 2003-09-23 | Christopher Franklin Bigge | Pharmaceutical preparation containing an uricosuric agent and an excitatory amino acid antagonist |
-
1992
- 1992-09-02 CA CA002115442A patent/CA2115442C/en not_active Expired - Fee Related
- 1992-09-02 DE DE69224069T patent/DE69224069T2/de not_active Expired - Fee Related
- 1992-09-02 AU AU25943/92A patent/AU660717B2/en not_active Ceased
- 1992-09-02 ES ES92919882T patent/ES2113957T3/es not_active Expired - Lifetime
- 1992-09-02 DK DK92919882T patent/DK0603301T3/da active
- 1992-09-02 AT AT92919882T patent/ATE162075T1/de not_active IP Right Cessation
- 1992-09-02 EP EP92919882A patent/EP0603301B1/en not_active Expired - Lifetime
- 1992-09-02 WO PCT/US1992/007540 patent/WO1993004688A1/en not_active Ceased
- 1992-09-02 JP JP50544593A patent/JP3218038B2/ja not_active Expired - Fee Related
- 1992-09-07 NZ NZ244243A patent/NZ244243A/en unknown
- 1992-09-08 PT PT100850A patent/PT100850B/pt not_active IP Right Cessation
- 1992-09-08 MX MX9205127A patent/MX9205127A/es not_active IP Right Cessation
- 1992-09-08 ZA ZA926837A patent/ZA926837B/xx unknown
-
1993
- 1993-04-19 US US08/049,228 patent/US5407935A/en not_active Expired - Fee Related
-
1994
- 1994-03-08 NO NO940809A patent/NO307645B1/no not_active IP Right Cessation
-
1995
- 1995-10-05 US US08/539,398 patent/US5627168A/en not_active Expired - Fee Related
-
1996
- 1996-12-31 US US08/775,637 patent/US5767119A/en not_active Expired - Fee Related
-
1998
- 1998-03-13 GR GR980400554T patent/GR3026369T3/el unknown
- 1998-03-27 US US09/049,495 patent/US5942513A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06510544A (ja) | 1994-11-24 |
| DE69224069D1 (de) | 1998-02-19 |
| US5942513A (en) | 1999-08-24 |
| MX9205127A (es) | 1993-07-01 |
| DE69224069T2 (de) | 1998-07-02 |
| GR3026369T3 (en) | 1998-06-30 |
| PT100850B (pt) | 1999-07-30 |
| AU660717B2 (en) | 1995-07-06 |
| US5407935A (en) | 1995-04-18 |
| CA2115442C (en) | 2003-09-23 |
| US5767119A (en) | 1998-06-16 |
| EP0603301A1 (en) | 1994-06-29 |
| NO940809L (no) | 1994-03-08 |
| DK0603301T3 (da) | 1998-09-14 |
| NO940809D0 (no) | 1994-03-08 |
| WO1993004688A1 (en) | 1993-03-18 |
| US5627168A (en) | 1997-05-06 |
| JP3218038B2 (ja) | 2001-10-15 |
| AU2594392A (en) | 1993-04-05 |
| NO307645B1 (no) | 2000-05-08 |
| PT100850A (pt) | 1993-10-29 |
| EP0603301B1 (en) | 1998-01-14 |
| NZ244243A (en) | 1995-07-26 |
| ES2113957T3 (es) | 1998-05-16 |
| CA2115442A1 (en) | 1993-03-18 |
| ATE162075T1 (de) | 1998-01-15 |
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