ZA931185B - Novel arylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use - Google Patents

Novel arylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use

Info

Publication number
ZA931185B
ZA931185B ZA931185A ZA931185A ZA931185B ZA 931185 B ZA931185 B ZA 931185B ZA 931185 A ZA931185 A ZA 931185A ZA 931185 A ZA931185 A ZA 931185A ZA 931185 B ZA931185 B ZA 931185B
Authority
ZA
South Africa
Prior art keywords
treatment
disturbances
hydrogen
compounds
arylcarbonylaminoalkyl
Prior art date
Application number
ZA931185A
Other languages
English (en)
Inventor
Heinrich Englert
Dieter Mania
David Wettlaufer
Erik Klaus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA931185B publication Critical patent/ZA931185B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
ZA931185A 1992-02-20 1993-02-19 Novel arylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use ZA931185B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92102828 1992-02-20

Publications (1)

Publication Number Publication Date
ZA931185B true ZA931185B (en) 1993-09-16

Family

ID=8209352

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA931185A ZA931185B (en) 1992-02-20 1993-02-19 Novel arylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use

Country Status (17)

Country Link
US (1) US5360808A (cs)
EP (1) EP0556738B1 (cs)
JP (1) JPH069560A (cs)
KR (1) KR930017895A (cs)
CN (1) CN1075480A (cs)
AT (1) ATE122659T1 (cs)
AU (1) AU3375993A (cs)
CA (1) CA2089955A1 (cs)
CZ (1) CZ403592A3 (cs)
DE (1) DE69300152D1 (cs)
FI (1) FI930716L (cs)
HU (1) HU9300463D0 (cs)
IL (1) IL104781A0 (cs)
MA (1) MA22806A1 (cs)
MX (1) MX9300915A (cs)
NO (1) NO930594L (cs)
ZA (1) ZA931185B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0016517A (pt) * 1999-12-21 2002-09-17 Monsanto Technology Llc Derivados diacila de diamina de propileno herbicidas
DE10205219A1 (de) * 2002-02-08 2003-08-21 Bayer Ag Chinoxalinone und ihre Verwendung
US6869966B2 (en) * 2002-09-30 2005-03-22 Banyu Pharmaceutical Co., Ltd. N-substituted-2-oxodihydropyridine derivatives
US20040127129A1 (en) * 2002-12-31 2004-07-01 Shuiyuan Luo Grooved-shape monofilaments and the fabrics made thereof
WO2007008963A1 (en) * 2005-07-13 2007-01-18 Jenrin Discovery Mao-b inhibitors useful for treating obesity
MX2009008531A (es) 2007-02-16 2009-08-26 Amgen Inc Cetonas de heterociclilo que contienen nitrogeno y su uso como inhibidores de c-met.
WO2010072599A1 (en) 2008-12-23 2010-07-01 F. Hoffmann-La Roche Ag Dihydropyridone ureas as p2x7 modulators
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
EP2391604A1 (en) 2008-12-23 2011-12-07 F. Hoffmann-La Roche AG Dihydropyridone amides as p2x7 modulators
MX2011006843A (es) 2008-12-23 2011-08-04 Hoffmann La Roche Dihidropiridona-amidas como moduladores de p2x7.
CN102264723B (zh) 2008-12-23 2014-12-10 霍夫曼-拉罗奇有限公司 作为p2x7调节剂的二氢吡啶酮酰胺
US8816085B2 (en) 2009-08-26 2014-08-26 Takeda Gmbh Methylpyrrolopyridinecarboxamides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2637477A1 (de) * 1976-08-20 1978-02-23 Hoechst Ag Dihydro-oxo-nicotinsaeuren und verfahren zu ihrer herstellung
NZ195564A (en) * 1979-11-26 1983-09-30 Sterling Drug Inc 5-pyridinyl-2(1h)-pyridinones pharmaceutical compositions intermediate pyridine compounds
US4297360A (en) * 1980-03-28 1981-10-27 Sterling Drug Inc. 5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use
IT8367883A0 (it) * 1982-08-23 1983-08-22 Rorer Int Overseas Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche
GB8809481D0 (en) * 1988-04-21 1988-05-25 Smith Kline French Lab Chemical compounds

Also Published As

Publication number Publication date
FI930716A0 (fi) 1993-02-18
EP0556738A1 (en) 1993-08-25
DE69300152D1 (de) 1995-06-22
HU9300463D0 (en) 1993-05-28
KR930017895A (ko) 1993-09-20
IL104781A0 (en) 1993-06-10
JPH069560A (ja) 1994-01-18
NO930594D0 (no) 1993-02-19
CZ403592A3 (en) 1993-12-15
EP0556738B1 (en) 1995-05-17
NO930594L (no) 1993-08-23
FI930716A7 (fi) 1993-08-21
ATE122659T1 (de) 1995-06-15
AU3375993A (en) 1993-08-26
FI930716L (fi) 1993-08-21
MA22806A1 (fr) 1993-10-01
CA2089955A1 (en) 1993-08-21
US5360808A (en) 1994-11-01
MX9300915A (es) 1993-09-01
CN1075480A (zh) 1993-08-25

Similar Documents

Publication Publication Date Title
ZA931185B (en) Novel arylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use
SE8801807L (sv) New benzo(b)pyranes and pyranopyridines, process for their production and their use
PH31123A (en) Benzimidazole compounds.
EP0330065B1 (en) Sulfonamide compounds
JPS60208987A (ja) ピリドベンゾチアジン誘導体の製造法
NO984532L (no) Nye tetralon- eller benzopyranonderivater og fremgangsmÕte for fremstilling derav
DE3835842A1 (de) Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
Monge et al. 3‐Amino‐2‐quinoxalinecarbonitrile. New fused quinoxalines with potential cytotoxic activity
HUT37792A (en) Process for production of derivatives of beta-carbolin-3-carbonic acid and medical preparatives containing such compounds
HU912786D0 (en) Process for producing 4-substituted-dihydro-pyrido(4,3-d) pyrimidine derivatives as well as pharmaceutical preparatives containing said compounds
ZA908460B (en) Benzocycloalkylaminopyridinamines and related compounds,a process and intermediates for their preparation and their use as medicaments
HU911277D0 (en) Process for producing sulfonyl-amino-substitued bicyclic hydroxam acid derivatives
AU621388B2 (en) The use of substituted 3,4-dihydro-2h-benzopyrans as remedies for constructive functional disorders of the lungs and/or disorders of the efferent urinary passages
HRP920948A2 (en) Nitratoalkanecarbone acid derivatives, process for the preparation thereof, the use of the same and drugs containing them
Nair et al. Synthesis of 10-thiofolic acid. Potential antibacterial and antitumor agent
CN118108704A (zh) Kif18a抑制剂
JPS57167999A (en) Novel 6 alpha-methylhydrocortisone derivative, manufacture and pharmaceutical medicine containing same for treating skin disease and respiratory and intestinal allergic disease
AU704210B2 (en) Synthesis of (S)-3-(2-thienylthio) butyric acid and analogs
ATE146176T1 (de) Benzo(b)thiophen-3-yl-piperazine, verfahren zur deren herstellung und ihre verwendung als arzneimittel
US5182278A (en) Analgesic benzoxazolinones having at the 6-position a 1-hydroxy-3-morpholinopropyl side chain
RU93004478A (ru) Новые арилкарбониламиноалкил-дигидро-оксо-пиридины, их получение и их применение
JPH02270848A (ja) 新規ジアミン化合物及びその製造法
JPS61268651A (ja) フエニル酢酸誘導体およびその製造法
US5364878A (en) Use of substituted 3,4-dihydro-2H-benzopyrans as remedies for obstructive functional disorders of the lungs
ATE28878T1 (de) Neue 6alpha-methylprednisolon-derivate ihre herstellung und verwendung.