ZA939337B - Pharmaceutical granulate - Google Patents

Pharmaceutical granulate

Info

Publication number
ZA939337B
ZA939337B ZA939337A ZA939337A ZA939337B ZA 939337 B ZA939337 B ZA 939337B ZA 939337 A ZA939337 A ZA 939337A ZA 939337 A ZA939337 A ZA 939337A ZA 939337 B ZA939337 B ZA 939337B
Authority
ZA
South Africa
Prior art keywords
carrier
mixture
optionally
granules
desogestrel
Prior art date
Application number
ZA939337A
Other languages
English (en)
Inventor
Jan Hendrik Dopper
Van Der Cornelis Josephus Maria Ven
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27578967&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA939337(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to US07/941,026 priority Critical patent/US5395627A/en
Priority to ES93203476T priority patent/ES2125300T3/es
Priority to AT93203476T priority patent/ATE173918T1/de
Priority to DK93203476T priority patent/DK0657161T3/da
Priority to DE69322396T priority patent/DE69322396T2/de
Priority to EP93203476A priority patent/EP0657161B1/de
Priority to NO934584A priority patent/NO306928B1/no
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to CA002111320A priority patent/CA2111320A1/en
Priority to NZ250443A priority patent/NZ250443A/en
Priority to FI935584A priority patent/FI111221B/fi
Priority to ZA939337A priority patent/ZA939337B/xx
Priority to AU52391/93A priority patent/AU672447B2/en
Priority to JP32229093A priority patent/JP3720385B2/ja
Priority to CN93121510A priority patent/CN1050043C/zh
Publication of ZA939337B publication Critical patent/ZA939337B/xx
Priority to US08/366,348 priority patent/US5527543A/en
Priority to GR990400353T priority patent/GR3029273T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
ZA939337A 1992-09-04 1993-12-13 Pharmaceutical granulate ZA939337B (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
US07/941,026 US5395627A (en) 1992-09-04 1992-09-04 Pharmaceutical granulate
ES93203476T ES2125300T3 (es) 1992-09-04 1993-12-10 Granulados farmaceuticos que contienen esteroides.
AT93203476T ATE173918T1 (de) 1992-09-04 1993-12-10 Steroide enthaltende pharmazeutische granulate
DK93203476T DK0657161T3 (da) 1992-09-04 1993-12-10 Farmaceutisk granulat indeholdende steroider
DE69322396T DE69322396T2 (de) 1992-09-04 1993-12-10 Steroide enthaltende pharmazeutische Granulate
EP93203476A EP0657161B1 (de) 1992-09-04 1993-12-10 Steroide enthaltende pharmazeutische Granulate
ZA939337A ZA939337B (en) 1992-09-04 1993-12-13 Pharmaceutical granulate
NO934584A NO306928B1 (no) 1992-09-04 1993-12-13 Fremgangsmåte for fremstilling av steroidholdige granuler, samt granuler og tablett
CA002111320A CA2111320A1 (en) 1992-09-04 1993-12-13 Pharmaceutical granulate
NZ250443A NZ250443A (en) 1992-09-04 1993-12-13 Preparation of film coated, steroid-loaded granules
FI935584A FI111221B (fi) 1992-09-04 1993-12-13 Menetelmä farmaseuttisten rakeiden valmistamiseksi
AU52391/93A AU672447B2 (en) 1992-09-04 1993-12-14 Pharmaceutical granulate
JP32229093A JP3720385B2 (ja) 1992-09-04 1993-12-21 医薬顆粒
CN93121510A CN1050043C (zh) 1992-09-04 1993-12-29 药物颗粒
US08/366,348 US5527543A (en) 1992-09-04 1994-12-29 Pharmaceutical granulate
GR990400353T GR3029273T3 (en) 1992-09-04 1999-02-03 Pharmaceutical granulate containing steroids.

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US07/941,026 US5395627A (en) 1992-09-04 1992-09-04 Pharmaceutical granulate
EP93203476A EP0657161B1 (de) 1992-09-04 1993-12-10 Steroide enthaltende pharmazeutische Granulate
NZ250443A NZ250443A (en) 1992-09-04 1993-12-13 Preparation of film coated, steroid-loaded granules
NO934584A NO306928B1 (no) 1992-09-04 1993-12-13 Fremgangsmåte for fremstilling av steroidholdige granuler, samt granuler og tablett
CA002111320A CA2111320A1 (en) 1992-09-04 1993-12-13 Pharmaceutical granulate
ZA939337A ZA939337B (en) 1992-09-04 1993-12-13 Pharmaceutical granulate
FI935584A FI111221B (fi) 1992-09-04 1993-12-13 Menetelmä farmaseuttisten rakeiden valmistamiseksi
AU52391/93A AU672447B2 (en) 1992-09-04 1993-12-14 Pharmaceutical granulate
JP32229093A JP3720385B2 (ja) 1992-09-04 1993-12-21 医薬顆粒
CN93121510A CN1050043C (zh) 1992-09-04 1993-12-29 药物颗粒

Publications (1)

Publication Number Publication Date
ZA939337B true ZA939337B (en) 1994-10-13

Family

ID=27578967

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA939337A ZA939337B (en) 1992-09-04 1993-12-13 Pharmaceutical granulate

Country Status (15)

Country Link
US (2) US5395627A (de)
EP (1) EP0657161B1 (de)
JP (1) JP3720385B2 (de)
CN (1) CN1050043C (de)
AT (1) ATE173918T1 (de)
AU (1) AU672447B2 (de)
CA (1) CA2111320A1 (de)
DE (1) DE69322396T2 (de)
DK (1) DK0657161T3 (de)
ES (1) ES2125300T3 (de)
FI (1) FI111221B (de)
GR (1) GR3029273T3 (de)
NO (1) NO306928B1 (de)
NZ (1) NZ250443A (de)
ZA (1) ZA939337B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976570A (en) * 1993-12-21 1999-11-02 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products
US6077533A (en) * 1994-05-25 2000-06-20 Purdue Pharma L.P. Powder-layered oral dosage forms
IL113816A (en) * 1994-06-08 1998-12-06 Akzo Nobel Nv Pharmaceutical compositions containing desogestrel their preparation and use
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
NZ312113A (en) * 1995-06-22 1998-06-26 Akzo Nobel Nv Compressed dry-granulation of desogestrel
WO1997004752A1 (en) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
DE19652196A1 (de) * 1996-12-16 1998-06-18 Jenapharm Gmbh Homogene steroidhaltige Präformulierungen zur Herstellung niedrigdosierter fester und halbfester pharmazeutischer Zubereitungen
DE69702985T2 (de) * 1997-09-23 2001-02-15 Akzo Nobel N.V., Arnheim/Arnhem Steroid enthaltende Dosierungsformen mit einer steroiddichten Umhüllung
US6756366B1 (en) * 1999-04-06 2004-06-29 Akzo Nobel N.V. Orally active androgens
DK1361881T3 (da) * 2000-12-14 2006-02-20 Ortho Mcneil Pharm Inc Steroide hormonprodukter og fremgangsmåder til fremstilling heraf
US6630166B1 (en) 2001-02-12 2003-10-07 Watson Pharmaceuticals, Inc. Compositions for conjugated estrogens and associated methods
US7303763B2 (en) * 2001-02-12 2007-12-04 Watson Laboratories, Inc. Compositions for conjugated estrogens and associated methods
DE60100389T2 (de) * 2001-07-11 2004-05-19 Apr Applied Pharma Research S.A. Fettlösliche Substanzen enthaltende Granulate und Verfahren zu ihrer Herstellung
TW200403075A (en) * 2002-05-29 2004-03-01 Akzo Nobel Nv Progestagenic dosage units
JP4756153B2 (ja) * 2004-08-27 2011-08-24 富士製薬工業株式会社 低成分含量の錠剤の製造方法
US20060183724A1 (en) * 2005-02-03 2006-08-17 Diliberti Charles E Compositions of unconjugated estrogens and methods for their use
US20070248665A1 (en) * 2006-04-24 2007-10-25 Sherman Bernard C Compositions comprising co-precipitate of eplerenone and a water-soluble excipient
CA2873961C (en) * 2012-05-14 2017-09-26 Shionogi & Co., Ltd. Preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives
CN105050708A (zh) 2012-11-14 2015-11-11 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
CN103271927A (zh) * 2013-05-31 2013-09-04 南通联亚药业有限公司 一种改进口服避孕药含量均匀性三级稀释法的工艺
CN103271928A (zh) * 2013-05-31 2013-09-04 南通联亚药业有限公司 一种改进去氧孕烯稳定性的处方工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180560A (en) * 1976-10-26 1979-12-25 Syntex Corporation Inert core implant pellet
JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
US5145675A (en) * 1986-03-31 1992-09-08 Advanced Polymer Systems, Inc. Two step method for preparation of controlled release formulations
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
ES2024010B3 (es) * 1987-07-06 1992-02-16 Akzo Nv Unidad de dosis farmaceutica.
IL92343A0 (en) * 1988-12-20 1990-07-26 Gist Brocades Nv Granulate for multiparticulate controlled release oral compositions,their preparation and oral pharmaceutical compositions containing them
US5035897A (en) * 1989-09-05 1991-07-30 Alza Corporation Dosage form for delivering soluble or insoluble drugs
US5284662A (en) * 1990-10-01 1994-02-08 Ciba-Geigy Corp. Oral osmotic system for slightly soluble active agents
IE71202B1 (en) * 1990-12-17 1997-02-12 Akzo Nv Progestagen-only contraceptive
US5200194A (en) * 1991-12-18 1993-04-06 Alza Corporation Oral osmotic device
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.

Also Published As

Publication number Publication date
EP0657161B1 (de) 1998-12-02
CA2111320A1 (en) 1995-06-14
DK0657161T3 (da) 1999-08-16
FI111221B (fi) 2003-06-30
NO934584D0 (no) 1993-12-13
ES2125300T3 (es) 1999-03-01
JP3720385B2 (ja) 2005-11-24
FI935584A0 (fi) 1993-12-13
AU672447B2 (en) 1996-10-03
CN1050043C (zh) 2000-03-08
US5395627A (en) 1995-03-07
NO934584L (no) 1995-06-14
DE69322396D1 (de) 1999-01-14
NO306928B1 (no) 2000-01-17
JPH07196513A (ja) 1995-08-01
DE69322396T2 (de) 1999-07-29
ATE173918T1 (de) 1998-12-15
CN1104487A (zh) 1995-07-05
EP0657161A1 (de) 1995-06-14
NZ250443A (en) 1995-07-26
AU5239193A (en) 1995-07-13
FI935584L (fi) 1995-06-14
GR3029273T3 (en) 1999-05-28
US5527543A (en) 1996-06-18

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