ZA93996B - Pyrrolidine compounds, processes for preparing them and pharmaceutical compositions containing them. - Google Patents

Pyrrolidine compounds, processes for preparing them and pharmaceutical compositions containing them.

Info

Publication number: ZA93996B
Authority: ZA; South Africa
Prior art keywords: group; optionally substituted; preparing; processes; pharmaceutical compositions
Prior art date: 1992-02-12

Application number

ZA93996A

Other languages

English (en)

Inventor

Gilbert Lavielle

Thierry Dubuffet

Olivier Muller

Michel Laubie

Tony Verbeuren

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-12

Filing date

1993-02-12

Publication date

1993-09-20

1993-02-12 Application filed by Adir filed Critical Adir

1993-09-20 Publication of ZA93996B publication Critical patent/ZA93996B/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
150000003235 pyrrolidines Chemical class 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
-1 phenylsulphonyl group Chemical group 0.000 abstract 2
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000005400 pyridylcarbonyl group Chemical group N1=C(C=CC=C1)C(=O)* 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

ZA93996A 1992-02-12 1993-02-12 Pyrrolidine compounds, processes for preparing them and pharmaceutical compositions containing them. ZA93996B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9201523A FR2687146B1 (fr)	1992-02-12	1992-02-12	Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
ZA93996B true ZA93996B (en)	1993-09-20

Family

ID=9426530

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA93996A ZA93996B (en)	1992-02-12	1993-02-12	Pyrrolidine compounds, processes for preparing them and pharmaceutical compositions containing them.

Country Status (13)

Country	Link
US (2)	US5387591A (ja)
EP (1)	EP0556119B1 (ja)
JP (1)	JPH0739385B2 (ja)
AT (1)	ATE153016T1 (ja)
AU (1)	AU655868B2 (ja)
CA (1)	CA2089349C (ja)
DE (1)	DE69310567T2 (ja)
DK (1)	DK0556119T3 (ja)
ES (1)	ES2105145T3 (ja)
FR (1)	FR2687146B1 (ja)
GR (1)	GR3023932T3 (ja)
NZ (1)	NZ245884A (ja)
ZA (1)	ZA93996B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2685325B1 (fr) *	1991-12-20	1994-02-04	Adir Cie	Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2722194B1 (fr) *	1994-07-06	1996-08-23	Adir	Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
JP4057088B2 (ja) *	1996-04-22	2008-03-05	株式会社カネカ	ピロリジン誘導体の製造方法
WO1998024791A1 (en) *	1996-12-06	1998-06-11	Abbott Laboratories	Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds
US5891882A (en) *	1996-12-06	1999-04-06	Abbott Laboratories	Benzopyranopyrrole and benzopyranopyridine α-1 adenergic compounds
TWI274750B (en)	1999-01-12	2007-03-01	Abbott Gmbh & Co Kg	Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
GB0002100D0 (en) *	2000-01-28	2000-03-22	Novartis Ag	Organic compounds
TW200302717A (en) *	2002-02-06	2003-08-16	Schering Corp	Novel gamma secretase inhibitors
JP2007507504A (ja) *	2003-09-30	2007-03-29	メルク　エンド　カムパニー　インコーポレーテッド	フェニルピロリジンエーテル系タキキニン受容体拮抗薬

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH24950A (en) *	1987-05-01	1990-12-26	Fujisawa Pharmaceutical Co	Pyrrolidine derivatives and pharmaceutical compositions containing the same
JPH0798795B2 (ja) *	1987-05-08	1995-10-25	塩野義製薬株式会社	スルホンアミド置換不飽和脂肪酸
US5130323A (en) *	1988-10-31	1992-07-14	Fujisawa Pharmaceutical Co., Ltd.	Pyrrolidine derivatives
US5128366A (en) *	1990-07-05	1992-07-07	Shinogi & Co., Ltd.	Pyrrole derivatives
US5157128A (en) *	1990-11-30	1992-10-20	Warner-Lambert Company	Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates
FR2685325B1 (fr) *	1991-12-20	1994-02-04	Adir Cie	Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

1992
- 1992-02-12 FR FR9201523A patent/FR2687146B1/fr not_active Expired - Fee Related
1993
- 1993-02-11 NZ NZ245884A patent/NZ245884A/en unknown
- 1993-02-11 EP EP93400340A patent/EP0556119B1/fr not_active Expired - Lifetime
- 1993-02-11 US US08/016,501 patent/US5387591A/en not_active Expired - Fee Related
- 1993-02-11 CA CA002089349A patent/CA2089349C/fr not_active Expired - Fee Related
- 1993-02-11 ES ES93400340T patent/ES2105145T3/es not_active Expired - Lifetime
- 1993-02-11 AU AU33010/93A patent/AU655868B2/en not_active Ceased
- 1993-02-11 DK DK93400340.1T patent/DK0556119T3/da active
- 1993-02-11 AT AT93400340T patent/ATE153016T1/de not_active IP Right Cessation
- 1993-02-11 DE DE69310567T patent/DE69310567T2/de not_active Expired - Fee Related
- 1993-02-12 ZA ZA93996A patent/ZA93996B/xx unknown
- 1993-02-12 JP JP5024421A patent/JPH0739385B2/ja not_active Expired - Lifetime
1994
- 1994-06-14 US US08/259,697 patent/US5407946A/en not_active Expired - Fee Related
1997
- 1997-06-30 GR GR970401580T patent/GR3023932T3/el unknown

Also Published As

Publication number	Publication date
AU3301093A (en)	1993-08-19
DE69310567D1 (de)	1997-06-19
DE69310567T2 (de)	1997-12-18
CA2089349A1 (fr)	1993-08-13
US5387591A (en)	1995-02-07
CA2089349C (fr)	2001-10-16
US5407946A (en)	1995-04-18
AU655868B2 (en)	1995-01-12
NZ245884A (en)	1994-11-25
JPH0739385B2 (ja)	1995-05-01
FR2687146A1 (fr)	1993-08-13
GR3023932T3 (en)	1997-09-30
EP0556119A1 (fr)	1993-08-18
ATE153016T1 (de)	1997-05-15
EP0556119B1 (fr)	1997-05-14
DK0556119T3 (da)	1997-12-15
ES2105145T3 (es)	1997-10-16
FR2687146B1 (fr)	1994-04-01
JPH069552A (ja)	1994-01-18

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YU34896A (sh)	1999-09-27	Supstituisani n-(indol-2-karbonil)-glicinamidi, njihovi intermedijeri i farmaceutske kompozicije
IL71324A0 (en)	1984-06-29	N-phenyl-n'-cycloalkylalkanoyl-piperazines,their production and pharmaceutical compositions containing them
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HUT61575A (en)	1993-01-28	Process for producing n-acetamido-n-phenyl glycineamide derivatives and pharmaceutical compositions comprising same
AU3301093A (en)	1993-08-19	New pyrrolidine compounds, process for preparing them and pharmaceutical compositions containing them
HU9201116D0 (en)	1992-06-29	Piperidine derivatives, process for their production, and medical preparations containing such compounds
ATE85974T1 (de)	1993-03-15	Disubstituierte benzylamine, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und ihre zwischenprodukte bei der herstellung.
EP0313458A3 (en)	1990-10-31	Imidazo(2,1-b)benzothiazoles and their acid addition salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them
NZ218243A (en)	1990-03-27	B-carboline derivatives and pharmaceutical compositions
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ZA912618B (en)	1992-01-29	3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them
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DE69104475D1 (de)	1994-11-10	Harnstoffderivate, ihre herstellung und deren enthaltende arzneimittel.
AU688969B2 (en)	1998-03-19	Carbamoyl carboxylic acid amides
JPS6461466A (en)	1989-03-08	Derivatives of ureylene, 2,4-triminopyrimidine- 3-oxide, preparation and use for cosmetic and pharmacological composition
ZA9420B (en)	1995-01-04	Preparation process for sulphurated derivatives of imidazole and the new internediates obtained.
ES8506634A1 (es)	1985-08-01	Un procedimiento para la preparacion de derivados de isoquinuclidina.
ATE94878T1 (de)	1993-10-15	Imidazobenzodiazepine und ihre saeureadditionssalze, verfahren und zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
NO942480L (no)	1994-06-30	Heterocyklus-substituerte benzylaminderivater som anti-retrovirale forbindelser
DE69103271D1 (de)	1994-09-08	Benzothiazolinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
GB1109308A (en)	1968-04-10	Heterocyclic alkanoic acid amides
ZA894399B (en)	1990-02-28	New derivatives of phenothiazine,their preparation and the compositions which contain them
NO963307L (no)	1996-10-09	Karbamoylmetylureaderivater
ES478502A1 (es)	1980-07-01	Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas
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