ZA951334B - Acronycine analogues a process for their preparation and the pharmaceutical compositions containing them - Google Patents
Acronycine analogues a process for their preparation and the pharmaceutical compositions containing themInfo
- Publication number
- ZA951334B ZA951334B ZA951334A ZA951334A ZA951334B ZA 951334 B ZA951334 B ZA 951334B ZA 951334 A ZA951334 A ZA 951334A ZA 951334 A ZA951334 A ZA 951334A ZA 951334 B ZA951334 B ZA 951334B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkoxy
- acronycine
- analogues
- acyl
- preparation
- Prior art date
Links
- SMPZPKRDRQOOHT-UHFFFAOYSA-N acronycine Chemical class CN1C2=CC=CC=C2C(=O)C2=C1C(C=CC(C)(C)O1)=C1C=C2OC SMPZPKRDRQOOHT-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000002252 acyl group Chemical group 0.000 abstract 4
- -1 diastereoisomers Chemical class 0.000 abstract 4
- 239000004215 Carbon black (E152) Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 229930195733 hydrocarbon Natural products 0.000 abstract 2
- 150000002430 hydrocarbons Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9401806A FR2716197B1 (fr) | 1994-02-17 | 1994-02-17 | Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA951334B true ZA951334B (en) | 1995-10-23 |
Family
ID=9460176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA951334A ZA951334B (en) | 1994-02-17 | 1995-02-17 | Acronycine analogues a process for their preparation and the pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5567707A (pt) |
| EP (1) | EP0668281B1 (pt) |
| JP (1) | JP2675271B2 (pt) |
| CN (1) | CN1055926C (pt) |
| AT (1) | ATE191216T1 (pt) |
| AU (1) | AU680080B2 (pt) |
| CA (1) | CA2142560C (pt) |
| DE (1) | DE69515922T2 (pt) |
| DK (1) | DK0668281T3 (pt) |
| ES (1) | ES2146722T3 (pt) |
| FI (1) | FI118767B (pt) |
| FR (1) | FR2716197B1 (pt) |
| GR (1) | GR3033003T3 (pt) |
| NO (1) | NO308472B1 (pt) |
| NZ (1) | NZ270509A (pt) |
| PT (1) | PT668281E (pt) |
| ZA (1) | ZA951334B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6130161A (en) | 1997-05-30 | 2000-10-10 | International Business Machines Corporation | Method of forming copper interconnections with enhanced electromigration resistance and reduced defect sensitivity |
| FR2772765B1 (fr) * | 1997-12-19 | 2000-03-17 | Adir | Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2856687B1 (fr) * | 2003-06-25 | 2005-09-16 | Servier Lab | Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2902792A1 (fr) * | 2006-06-21 | 2007-12-28 | Servier Lab | Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624087A (en) * | 1967-07-17 | 1971-11-30 | Lilly Co Eli | Synthesis of acronycine and related compounds |
| US3621041A (en) * | 1968-07-05 | 1971-11-16 | Lilly Co Eli | Chromans |
| US3673163A (en) * | 1970-06-16 | 1972-06-27 | Lilly Co Eli | Pharmacological preparation containing an acronycine-polyvinylprrolidone coprecipitate |
| US3657249A (en) * | 1970-10-12 | 1972-04-18 | Lilly Co Eli | Synthesis of nordihydroacronycine and related compounds |
| US3715359A (en) * | 1971-07-02 | 1973-02-06 | Lilly Co Eli | Hydroxylated acronycine |
| US3943137A (en) * | 1973-07-09 | 1976-03-09 | University Of Kansas Endowment Association | Acronycine derivatives |
-
1994
- 1994-02-17 FR FR9401806A patent/FR2716197B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-15 CA CA002142560A patent/CA2142560C/fr not_active Expired - Fee Related
- 1995-02-15 JP JP7026866A patent/JP2675271B2/ja not_active Expired - Fee Related
- 1995-02-15 DK DK95400314T patent/DK0668281T3/da active
- 1995-02-15 ES ES95400314T patent/ES2146722T3/es not_active Expired - Lifetime
- 1995-02-15 AT AT95400314T patent/ATE191216T1/de not_active IP Right Cessation
- 1995-02-15 FI FI950681A patent/FI118767B/fi active
- 1995-02-15 DE DE69515922T patent/DE69515922T2/de not_active Expired - Fee Related
- 1995-02-15 EP EP95400314A patent/EP0668281B1/fr not_active Expired - Lifetime
- 1995-02-15 PT PT95400314T patent/PT668281E/pt unknown
- 1995-02-16 AU AU12287/95A patent/AU680080B2/en not_active Ceased
- 1995-02-16 NZ NZ270509A patent/NZ270509A/en not_active IP Right Cessation
- 1995-02-16 US US08/389,798 patent/US5567707A/en not_active Expired - Lifetime
- 1995-02-16 NO NO950574A patent/NO308472B1/no unknown
- 1995-02-17 ZA ZA951334A patent/ZA951334B/xx unknown
- 1995-02-17 CN CN95102005A patent/CN1055926C/zh not_active Expired - Fee Related
-
2000
- 2000-03-30 GR GR20000400612T patent/GR3033003T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2142560A1 (fr) | 1995-08-18 |
| AU680080B2 (en) | 1997-07-17 |
| NO950574L (no) | 1995-08-18 |
| EP0668281A1 (fr) | 1995-08-23 |
| CN1055926C (zh) | 2000-08-30 |
| FI118767B (fi) | 2008-03-14 |
| DE69515922D1 (de) | 2000-05-04 |
| NO950574D0 (no) | 1995-02-16 |
| NZ270509A (en) | 1996-03-26 |
| JPH07252257A (ja) | 1995-10-03 |
| FI950681L (fi) | 1995-08-18 |
| CN1113490A (zh) | 1995-12-20 |
| FI950681A0 (fi) | 1995-02-15 |
| DK0668281T3 (da) | 2000-08-14 |
| ES2146722T3 (es) | 2000-08-16 |
| NO308472B1 (no) | 2000-09-18 |
| JP2675271B2 (ja) | 1997-11-12 |
| ATE191216T1 (de) | 2000-04-15 |
| EP0668281B1 (fr) | 2000-03-29 |
| GR3033003T3 (en) | 2000-07-31 |
| DE69515922T2 (de) | 2000-11-02 |
| AU1228795A (en) | 1995-08-24 |
| FR2716197B1 (fr) | 1996-04-19 |
| FR2716197A1 (fr) | 1995-08-18 |
| PT668281E (pt) | 2000-07-31 |
| US5567707A (en) | 1996-10-22 |
| CA2142560C (fr) | 2002-04-09 |
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