ZA9610245B - Neuroprotective agents. - Google Patents

Neuroprotective agents.

Info

Publication number: ZA9610245B
Authority: ZA; South Africa
Prior art keywords: neuroprotective agents; neuroprotective; agents
Prior art date: 1995-12-07

Application number

ZA9610245A

Other languages

English (en)

Inventor

Stephen Shi-Hsun Lin

Katherine Lu Molnar-Kimber

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-07

Filing date

1996-12-05

Publication date

1998-06-05

1996-12-05 Application filed by American Home Prod filed Critical American Home Prod

1998-06-05 Publication of ZA9610245B publication Critical patent/ZA9610245B/xx

Links

239000004090 neuroprotective agent Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Physiology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Nutrition Science (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA9610245A 1995-12-07 1996-12-05 Neuroprotective agents. ZA9610245B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US833795P	1995-12-07	1995-12-07

Publications (1)

Publication Number	Publication Date
ZA9610245B true ZA9610245B (en)	1998-06-05

Family

ID=21731060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9610245A ZA9610245B (en)	1995-12-07	1996-12-05	Neuroprotective agents.

Country Status (23)

Country	Link
EP (1)	EP0778023B1 (cs)
JP (1)	JPH09183727A (cs)
KR (1)	KR970032856A (cs)
CN (1)	CN1112925C (cs)
AR (1)	AR008747A1 (cs)
AT (1)	ATE234095T1 (cs)
AU (1)	AU700653B2 (cs)
BR (1)	BR9605895A (cs)
CA (1)	CA2192298A1 (cs)
CZ (2)	CZ354496A3 (cs)
DE (1)	DE69626610T2 (cs)
DK (1)	DK0778023T3 (cs)
ES (1)	ES2188730T3 (cs)
HU (1)	HUP9603370A3 (cs)
IL (1)	IL119778A (cs)
MX (1)	MX9606131A (cs)
NO (1)	NO309966B1 (cs)
NZ (1)	NZ299888A (cs)
PT (1)	PT778023E (cs)
SI (1)	SI0778023T1 (cs)
SK (1)	SK154796A3 (cs)
TW (1)	TW427904B (cs)
ZA (1)	ZA9610245B (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1002535A1 (en)	1998-10-28	2000-05-24	Hrissanthi Ikonomidou	New use of glutamate antagonists for the treatment of cancer
US7253169B2 (en)	1999-11-12	2007-08-07	Gliamed, Inc.	Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) *	1999-11-12	2002-07-09	Gpi Nil Holdings, Inc.	AZA compounds, pharmaceutical compositions and methods of use
FR2806626B1 (fr) *	2000-03-22	2003-11-28	Centre Nat Rech Scient	Utilisation de substances modulatrices de l'expression ou de la fonction d'une proteine impliquee dans le cycle cellulaire pour le traitement ou la prevention des lesions neurales aigues
AU2001255406A1 (en) *	2000-04-17	2001-10-30	Gpi Nil Holdings, Inc.	Cyclic diaza compounds for treating neurodegenerative disorders
GB0117645D0 (en) *	2001-07-19	2001-09-12	Isis Innovation	Therapeutic stratergies for prevention and treatment of alzheimers disease
UA78529C2 (en)	2001-10-10	2007-04-10	Wyeth Corp	Derivatives of [[2-(amino-3,4-dioxo-1-cyclobutene-1-yl)amino]alkyl] acid for treating pain
US20030176455A1 (en) *	2002-03-13	2003-09-18	Wyeth	Method of inhibiting cell death
BRPI0409088A (pt) *	2003-04-09	2006-04-11	Wyeth Corp	composições farmacêuticas para administração intranasal de ácido [2-(8,9-dioxo-2,6-diazabiciclo [5.2.0]non-1(7)-en-2-il)alquil]-fosfÈnico e derivados e métodos de uso dos mesmos
PT1611144E (pt)	2003-04-09	2010-11-12	Wyeth Llc	Derivados do ácido 2-(8,9-dioxo-2,6-diazabiciclo(5.2.0)- non-1(7)-eno-2-il)-alquil-fosfónico e sua utilização como antagonistas do receptor n-metil-d-aspartato (nmda)
US20070155771A1 (en) *	2003-04-11	2007-07-05	David Rubinsztein	Methods and means for treating protein conformational disorders
US7485706B2 (en) *	2003-07-30	2009-02-03	The Board Of Trustees Of The Leland Stanford Junior University	Neurodegenerative protein aggregation inhibition methods and compounds
GT200400213A (es)	2003-10-22	2007-09-05		Metodos para la preparacion del acido {2-[(8,9)-dioxo-2,6-diaza-biciclo[5.2.0]-non-1(7)-en-2-il]etil} fosfonico y esteres del mismo
RU2007119585A (ru)	2004-12-20	2009-01-27	Вайет (Us)	Производные рапамицина и их применение при лечении неврологических заболеваний
SG158143A1 (en)	2004-12-20	2010-01-29	Wyeth Corp	Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders
JP4857071B2 (ja) *	2006-10-12	2012-01-18	潤平笹部	筋萎縮性側策硬化症（ａｌｓ）の検出方法
EP2065038A1 (en)	2007-11-30	2009-06-03	Pharnext	New therapeutic approaches for treating Charcot-Marie-Tooth disease
EP2135607A1 (en)	2008-06-18	2009-12-23	Pharnext	Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
KR20130128018A (ko) *	2009-04-10	2013-11-25	하이얀 치	새로운 노화 방지 물질 및 그 확인 방법
EP2263665A1 (en)	2009-06-02	2010-12-22	Pharnext	New compositions for treating CMT and related disorders
US9393241B2 (en)	2009-06-02	2016-07-19	Pharnext	Compositions for treating CMT and related disorders
US20120122913A1 (en) *	2009-07-24	2012-05-17	Institut National De La Recherche Scientifque	Combination of curcuminoids and mtor inhibitors for the treatment of tauopathies
US9121859B2 (en) *	2012-12-04	2015-09-01	Siemens Healthcare Diagnostics Inc.	Compounds and methods for determination of FKBP-binding immunosuppressant drugs
SMT201800534T1 (it)	2013-06-05	2019-01-11	Pharnext	Soluzioni orali stabili per principi attivi farmaceutici combinati
US9700544B2 (en)	2013-12-31	2017-07-11	Neal K Vail	Oral rapamycin nanoparticle preparations
US10383870B2 (en)	2016-06-10	2019-08-20	Pharnext	Early treatment of CMT disease
JP2021502971A (ja) *	2017-11-15	2021-02-04	ヴァンダービルトユニヴァーシティ	リソソーム機能の改善および神経変性疾患の治療のための方法および組成物
CN114366738A (zh) *	2021-12-20	2022-04-19	中国人民解放军军事科学院军事医学研究院	雷帕霉素在促进神经干细胞扩增中的用途
CN119639757B (zh) *	2024-12-11	2025-07-22	庐山市绿游生态农业开发有限公司	一种红藻氨酸受体及其抑制剂在防治橘小实蝇中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206018A (en) *	1978-11-03	1993-04-27	Ayerst, Mckenna & Harrison, Inc.	Use of rapamycin in treatment of tumors
JPH04230389A (ja) *	1990-07-16	1992-08-19	American Home Prod Corp	ラパマイシン誘導体
US5078999A (en) *	1991-02-22	1992-01-07	American Home Products Corporation	Method of treating systemic lupus erythematosus
IL101353A0 (en) *	1991-04-03	1992-11-15	American Home Prod	Pharmaceutical compositions for treating diabetes
DE4118740A1 (de) *	1991-06-05	1992-12-10	Schering Ag	Neue kombinationspraeparate zur behandlung des morbus parkinson
IL102414A (en) *	1991-07-25	1996-08-04	Univ Louisville Res Found	Medicinal preparations for the treatment of ocular inflammation, containing rapamycin
US5260299A (en) *	1992-03-05	1993-11-09	American Home Products Corporation	Rapamycin 42-sulfonates and 42-(N-Carboalkoxy)Sulfamates Useful as Immunosuppressive Agents
IL111003A0 (en) *	1993-09-30	1994-11-28	American Home Prod	Multi-component oral rapamycin formulation

1996
- 1996-11-28 TW TW085114700A patent/TW427904B/zh not_active IP Right Cessation
- 1996-12-04 CZ CZ963544A patent/CZ354496A3/cs unknown
- 1996-12-04 EP EP96308786A patent/EP0778023B1/en not_active Expired - Lifetime
- 1996-12-04 AT AT96308786T patent/ATE234095T1/de not_active IP Right Cessation
- 1996-12-04 ES ES96308786T patent/ES2188730T3/es not_active Expired - Lifetime
- 1996-12-04 SI SI9630586T patent/SI0778023T1/xx unknown
- 1996-12-04 SK SK1547-96A patent/SK154796A3/sk unknown
- 1996-12-04 DK DK96308786T patent/DK0778023T3/da active
- 1996-12-04 PT PT96308786T patent/PT778023E/pt unknown
- 1996-12-04 CZ CZ9864A patent/CZ6498A3/cs unknown
- 1996-12-04 DE DE69626610T patent/DE69626610T2/de not_active Expired - Fee Related
- 1996-12-05 KR KR1019960062011A patent/KR970032856A/ko not_active Ceased
- 1996-12-05 AU AU74178/96A patent/AU700653B2/en not_active Ceased
- 1996-12-05 MX MX9606131A patent/MX9606131A/es unknown
- 1996-12-05 ZA ZA9610245A patent/ZA9610245B/xx unknown
- 1996-12-05 NZ NZ299888A patent/NZ299888A/en unknown
- 1996-12-06 CN CN96123098A patent/CN1112925C/zh not_active Expired - Fee Related
- 1996-12-06 NO NO965238A patent/NO309966B1/no not_active IP Right Cessation
- 1996-12-06 HU HU9603370A patent/HUP9603370A3/hu unknown
- 1996-12-06 BR BR9605895A patent/BR9605895A/pt not_active Application Discontinuation
- 1996-12-06 AR ARP960105543A patent/AR008747A1/es not_active Application Discontinuation
- 1996-12-06 CA CA002192298A patent/CA2192298A1/en not_active Abandoned
- 1996-12-06 IL IL11977896A patent/IL119778A/xx not_active IP Right Cessation
- 1996-12-06 JP JP8326582A patent/JPH09183727A/ja active Pending

Also Published As

Publication number	Publication date
ES2188730T3 (es)	2003-07-01
HUP9603370A3 (en)	1998-12-28
DE69626610T2 (de)	2003-10-02
PT778023E (pt)	2003-06-30
CZ354496A3 (cs)	1998-03-18
NZ299888A (en)	2001-02-23
NO965238L (no)	1997-06-09
BR9605895A (pt)	1998-08-18
AU7417896A (en)	1997-06-12
AU700653B2 (en)	1999-01-14
IL119778A0 (en)	1997-03-18
CN1112925C (zh)	2003-07-02
AR008747A1 (es)	2000-02-23
HUP9603370A2 (en)	1997-05-28
CA2192298A1 (en)	1997-06-08
MX9606131A (es)	1997-08-30
CZ6498A3 (cs)	1998-06-17
HU9603370D0 (en)	1997-01-28
DE69626610D1 (de)	2003-04-17
EP0778023A1 (en)	1997-06-11
CN1159915A (zh)	1997-09-24
NO309966B1 (no)	2001-04-30
JPH09183727A (ja)	1997-07-15
TW427904B (en)	2001-04-01
NO965238D0 (no)	1996-12-06
SK154796A3 (en)	1997-09-10
EP0778023B1 (en)	2003-03-12
IL119778A (en)	1999-07-14
ATE234095T1 (de)	2003-03-15
DK0778023T3 (da)	2003-06-30
KR970032856A (ko)	1997-07-22
SI0778023T1 (en)	2003-08-31

Publication	Publication Date	Title
ZA967315B (en)	1998-03-02	Biphenylamides.
MX213417B (es)	2003-03-27	Fenilpiridazinonas.
HU9603370D0 (en)	1997-01-28	Neuroprotective agents
ZA961444B (en)	1997-08-25	Pyrazolylbenzoyl derivatives.
ZA964468B (en)	1997-02-06	Triazolylmethyl-cyclopentanols.
ZA969648B (en)	1998-05-18	Nozzle.
ZA961955B (en)	1997-09-11	Indazolecarboxamides.
ZA961449B (en)	1997-08-25	Isoxazolylbenzoyl derivatives.
ZA969973B (en)	1998-05-27	2-thioxo-imidazolidin-4-one derivatives.
ZA965365B (en)	1997-12-29	Antifungal agents.
DE69610844D1 (en)	2000-12-07	Hydroformylierungsverfahren.
ZA967741B (en)	1998-03-13	Diarylalkenylamine derivatives.
PL326837A1 (en)	1998-10-26	25-hydroxy-16-ene-26, 27-bishomocholecarctiferoles
ZA962821B (en)	1997-10-09	4-indolylpiperazinyl derivatives.
ZA966399B (en)	1997-02-19	Endothelin-receptor-antagonists.
ZA965494B (en)	1997-12-29	Therapeutic agents.
ZA967357B (en)	1998-03-02	Pyrazol-4-ylbenzoyl derivatives.
ZA966750B (en)	1997-02-18	Halogenobenzimidazoles.
ZA966933B (en)	1997-02-19	Endothelin-receptor-antagonists.
HUP0004486A3 (en)	2002-11-28	Neuroprotective agents
ZA967314B (en)	1998-03-02	Carbamoylcarboxamides.
ZA964034B (en)	1997-11-21	N-aminopyridone derivatives.
ZA969560B (en)	1998-05-14	Substituted 1-methyl-3-phenylpyrazoles.
ZA965962B (en)	1997-01-31	Anti-piroplasmotic agent
ZA968953B (en)	1997-07-30	24-homo-26,27-hexafluoro-cholecalciferols