ZA961994B - Piperidine derivatives process for the preparation thereof and application thereof in therapeutics - Google Patents

Piperidine derivatives process for the preparation thereof and application thereof in therapeutics

Info

Publication number
ZA961994B
ZA961994B ZA961994A ZA961994A ZA961994B ZA 961994 B ZA961994 B ZA 961994B ZA 961994 A ZA961994 A ZA 961994A ZA 961994 A ZA961994 A ZA 961994A ZA 961994 B ZA961994 B ZA 961994B
Authority
ZA
South Africa
Prior art keywords
therapeutics
preparation
application
piperidine derivatives
derivatives process
Prior art date
Application number
ZA961994A
Other languages
English (en)
Inventor
Luc Even
Samir Jegham
Gerard Defosse
Michel Aletru
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA961994B publication Critical patent/ZA961994B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
ZA961994A 1995-03-13 1996-03-12 Piperidine derivatives process for the preparation thereof and application thereof in therapeutics ZA961994B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502863A FR2731708B1 (fr) 1995-03-13 1995-03-13 Derives de piperidine, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA961994B true ZA961994B (en) 1996-09-03

Family

ID=9476960

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA961994A ZA961994B (en) 1995-03-13 1996-03-12 Piperidine derivatives process for the preparation thereof and application thereof in therapeutics

Country Status (15)

Country Link
EP (1) EP0732334A1 (cs)
JP (1) JPH08269058A (cs)
KR (1) KR960034205A (cs)
CN (1) CN1140174A (cs)
AU (1) AU4800896A (cs)
CA (1) CA2171579A1 (cs)
CZ (1) CZ75496A3 (cs)
FR (1) FR2731708B1 (cs)
HU (1) HUP9600624A2 (cs)
IL (1) IL117455A0 (cs)
NO (1) NO961000L (cs)
NZ (1) NZ286164A (cs)
PL (1) PL313204A1 (cs)
SK (1) SK34196A3 (cs)
ZA (1) ZA961994B (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231887A1 (en) * 1995-09-18 1997-03-27 Glaxo Group Limited 5-ht3 receptor antagonists for dyskinesia
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
FR2801589A1 (fr) * 1999-11-25 2001-06-01 Sanofi Synthelabo Derives de 2-arylquinoleine, leur preparation et leur application en therapeutique
HRP20030081A2 (en) 2000-08-08 2005-02-28 Sanofi-Aventis Benzimidazole derivatives, preparation and therapeutic use thereof
FR2816619B1 (fr) * 2000-11-15 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816942B1 (fr) 2000-11-23 2003-05-09 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816941B1 (fr) * 2000-11-23 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
US9227985B2 (en) * 2013-03-15 2016-01-05 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
EP3019502B1 (en) * 2013-07-08 2017-05-17 Incyte Holdings Corporation Tricyclic heterocycles as bet protein inhibitors
US9399640B2 (en) 2013-11-26 2016-07-26 Incyte Corporation Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
WO2015081189A1 (en) 2013-11-26 2015-06-04 Incyte Corporation Bicyclic heterocycles as bet protein inhibitors
US9309246B2 (en) 2013-12-19 2016-04-12 Incyte Corporation Tricyclic heterocycles as BET protein inhibitors
MY180775A (en) 2014-04-23 2020-12-09 Incyte Corp 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins
US9527864B2 (en) 2014-09-15 2016-12-27 Incyte Corporation Tricyclic heterocycles as BET protein inhibitors
WO2017075377A1 (en) 2015-10-29 2017-05-04 Incyte Corporation Amorphous solid form of a bet protein inhibitor
KR102643344B1 (ko) 2016-06-20 2024-03-07 인사이트 코포레이션 Bet 저해제의 결정질 고체 형태
US11535633B2 (en) * 2018-06-28 2022-12-27 Jiangsu Hengrui Medicine Co., Ltd. Fused tricyclic heterocycle compounds and therapeutic uses thereof
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674855B1 (fr) * 1991-04-03 1994-01-14 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
FR2710915B1 (fr) * 1993-10-04 1995-11-24 Synthelabo Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.

Also Published As

Publication number Publication date
PL313204A1 (en) 1996-09-16
NZ286164A (en) 1996-11-26
SK34196A3 (en) 1996-10-02
FR2731708A1 (fr) 1996-09-20
FR2731708B1 (fr) 1997-04-30
CZ75496A3 (en) 1996-10-16
NO961000L (no) 1996-09-16
JPH08269058A (ja) 1996-10-15
EP0732334A1 (fr) 1996-09-18
IL117455A0 (en) 1996-07-23
CN1140174A (zh) 1997-01-15
CA2171579A1 (en) 1996-09-14
NO961000D0 (no) 1996-03-12
HUP9600624A2 (en) 1997-01-28
KR960034205A (ko) 1996-10-22
HU9600624D0 (en) 1996-05-28
AU4800896A (en) 1996-09-26

Similar Documents

Publication Publication Date Title
IL107132A0 (en) Piperidine derivatives,their preparation and their application in therapeutics
IL116851A0 (en) 3-arylidene-2-oxindole derivatives their preparation and use
SI0734260T1 (sl) Paroksetinske tablete in postopek za njihovo pripravo
IL117455A0 (en) Piperidine derivatives process for the preparation thereof and application thereof in therapeutics
IL111148A0 (en) Imidazol-4- ylpiperidine derivatives, their preparation and their application in therapeutics
GB9510716D0 (en) Substituted camptothecin derivatives and process for their preparation
CY2291B1 (en) 1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics
ZA988921B (en) 3,4-diarylthiazolin-2-one or -2-thione derivatives their methods of preparation and their uses in therapeutics
GB9705035D0 (en) Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation
EG23781A (en) Pharmaceutical composition containing tiagabine hydrochloride and the process for its preparation
SG44059A1 (en) Process for preparing acetoxyazetidinone derivative and intermediate thereof
ZA943649B (en) Piperidine derivatives their preparation and use
HU216713B (hu) Ciklusos acetálok és eljárás az előállításukra
IL107133A0 (en) Piperidine derivatives,their preparation and their application in therapy
AUPN002694A0 (en) Improvements in and relating to hangers for garments
ZA985727B (en) (1H-imidazol-4-YL) piperidine derivatives their preparation and their application in therapeutics
GB2306985B (en) Improvements in milling
GB2302691B (en) Oxaindene derivatives and process for the preparation thereof
ZA967558B (en) Alpha-phenylpiperidine-1-propanol derivatives their preparation and their application in therapeutics
HUP9601521A2 (en) Substituted quinoline-intermediates and process for preparation the same
GB2299595B (en) Improvements in firrings for conservatories
GB9513979D0 (en) Improvements in or relating to supports for partitions and the like
AU7423196A (en) Improvements in cots
KR0159645B1 (en) Process for the preparation of poly--hydroxybutyrate-(o-ñô-hydroxyvalerate)and strain for using in said process
HUP9601520A3 (en) Substituted quinoline-intermediates and process for preparation the same