ZA96403B - Racemisation - Google Patents
RacemisationInfo
- Publication number
- ZA96403B ZA96403B ZA96403A ZA96403A ZA96403B ZA 96403 B ZA96403 B ZA 96403B ZA 96403 A ZA96403 A ZA 96403A ZA 96403 A ZA96403 A ZA 96403A ZA 96403 B ZA96403 B ZA 96403B
- Authority
- ZA
- South Africa
- Prior art keywords
- compound
- alkylated
- piperidine
- racemisation
- racemised
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 abstract 1
- 229960004288 levobupivacaine Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- -1 piperidine-2-carboxanilide compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Rolling Contact Bearings (AREA)
- Optical Head (AREA)
- Beans For Foods Or Fodder (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9501071.6A GB9501071D0 (en) | 1995-01-18 | 1995-01-18 | Racemisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA96403B true ZA96403B (en) | 1997-01-20 |
Family
ID=10768271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA96403A ZA96403B (en) | 1995-01-18 | 1996-01-18 | Racemisation |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0804417B1 (da) |
| JP (1) | JP4015696B2 (da) |
| KR (1) | KR100404390B1 (da) |
| CN (1) | CN1172912C (da) |
| AT (1) | ATE242214T1 (da) |
| AU (1) | AU701221B2 (da) |
| BR (1) | BR9606821A (da) |
| CA (1) | CA2208522C (da) |
| DE (1) | DE69628540T2 (da) |
| DK (1) | DK0804417T3 (da) |
| ES (1) | ES2201166T3 (da) |
| FI (1) | FI117437B (da) |
| GB (1) | GB9501071D0 (da) |
| HU (1) | HU227426B1 (da) |
| MX (1) | MX9705428A (da) |
| NO (1) | NO308843B1 (da) |
| PL (1) | PL184091B1 (da) |
| PT (1) | PT804417E (da) |
| WO (1) | WO1996022281A1 (da) |
| ZA (1) | ZA96403B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0002246A (pt) | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| EP1575569B1 (en) | 2002-12-13 | 2010-09-29 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
| RS52198B (sr) | 2004-09-17 | 2012-10-31 | Durect Corporation | Rastvor lokalnog anestetika koji sadrži saib sa održivim delovanjem |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| ES2388355T3 (es) | 2006-11-03 | 2012-10-11 | Durect Corporation | Sistemas de suministro transdémico que comprenden bupivacaína |
| EP2219622A1 (en) | 2007-12-06 | 2010-08-25 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| CN102093284B (zh) * | 2010-12-29 | 2013-05-08 | 宜昌人福药业有限责任公司 | 富集哌啶-2-甲酰苯胺类旋光化合物的方法 |
| JP2016515523A (ja) | 2013-03-15 | 2016-05-30 | デュレクト コーポレーション | 溶解変動性を低減させるためのレオロジー改質剤を有する組成物 |
| MY205229A (en) | 2016-07-06 | 2024-10-08 | Durect Corp | Oral dosage form with drug composition, barrier layer and drug layer |
| CN106187864B (zh) * | 2016-07-11 | 2018-11-23 | 江苏天和制药有限公司 | 一种由盐酸布比卡因制备高纯度布比卡因碱的方法 |
| BR112022013784A2 (pt) | 2020-01-13 | 2022-10-11 | Durect Corp | Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados |
| CA3203561A1 (en) | 2021-01-12 | 2022-07-21 | Adrian Neil Verity | Sustained release drug delivery systems and related methods |
| WO2023158722A2 (en) * | 2022-02-16 | 2023-08-24 | Teva Pharmaceuticals International Gmbh | Processes for preparation of avacopan and intermediates thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2301498A1 (fr) * | 1975-02-20 | 1976-09-17 | Maggioni & C Spa | Methode pour la racemisation d'une lysine optiquement active |
-
1995
- 1995-01-18 GB GBGB9501071.6A patent/GB9501071D0/en active Pending
-
1996
- 1996-01-12 PT PT96900349T patent/PT804417E/pt unknown
- 1996-01-12 DK DK96900349T patent/DK0804417T3/da active
- 1996-01-12 WO PCT/GB1996/000067 patent/WO1996022281A1/en not_active Ceased
- 1996-01-12 AT AT96900349T patent/ATE242214T1/de active
- 1996-01-12 KR KR1019970704822A patent/KR100404390B1/ko not_active Expired - Lifetime
- 1996-01-12 HU HU9901418A patent/HU227426B1/hu unknown
- 1996-01-12 PL PL96321378A patent/PL184091B1/pl unknown
- 1996-01-12 EP EP96900349A patent/EP0804417B1/en not_active Expired - Lifetime
- 1996-01-12 CN CNB961915242A patent/CN1172912C/zh not_active Expired - Lifetime
- 1996-01-12 AU AU43948/96A patent/AU701221B2/en not_active Expired
- 1996-01-12 CA CA002208522A patent/CA2208522C/en not_active Expired - Lifetime
- 1996-01-12 BR BR9606821A patent/BR9606821A/pt unknown
- 1996-01-12 MX MX9705428A patent/MX9705428A/es unknown
- 1996-01-12 DE DE69628540T patent/DE69628540T2/de not_active Expired - Lifetime
- 1996-01-12 ES ES96900349T patent/ES2201166T3/es not_active Expired - Lifetime
- 1996-01-12 JP JP52210296A patent/JP4015696B2/ja not_active Expired - Lifetime
- 1996-01-18 ZA ZA96403A patent/ZA96403B/xx unknown
-
1997
- 1997-07-17 FI FI973040A patent/FI117437B/fi not_active IP Right Cessation
- 1997-07-17 NO NO973312A patent/NO308843B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4015696B2 (ja) | 2007-11-28 |
| GB9501071D0 (en) | 1995-03-08 |
| DE69628540D1 (de) | 2003-07-10 |
| FI117437B (fi) | 2006-10-13 |
| CN1172912C (zh) | 2004-10-27 |
| NO308843B1 (no) | 2000-11-06 |
| DE69628540T2 (de) | 2004-01-08 |
| PL321378A1 (en) | 1997-12-08 |
| EP0804417B1 (en) | 2003-06-04 |
| EP0804417A1 (en) | 1997-11-05 |
| PT804417E (pt) | 2003-09-30 |
| JPH11501905A (ja) | 1999-02-16 |
| FI973040L (fi) | 1997-07-17 |
| MX9705428A (es) | 1997-11-29 |
| AU701221B2 (en) | 1999-01-21 |
| AU4394896A (en) | 1996-08-07 |
| CA2208522C (en) | 2007-03-13 |
| WO1996022281A1 (en) | 1996-07-25 |
| HUP9901418A2 (hu) | 1999-08-30 |
| FI973040A0 (fi) | 1997-07-17 |
| HU227426B1 (en) | 2011-05-30 |
| PL184091B1 (pl) | 2002-08-30 |
| ATE242214T1 (de) | 2003-06-15 |
| NO973312L (no) | 1997-07-17 |
| ES2201166T3 (es) | 2004-03-16 |
| BR9606821A (pt) | 1997-12-23 |
| CA2208522A1 (en) | 1996-07-25 |
| NO973312D0 (no) | 1997-07-17 |
| CN1168134A (zh) | 1997-12-17 |
| KR19980701432A (ko) | 1998-05-15 |
| HUP9901418A3 (en) | 2001-01-29 |
| DK0804417T3 (da) | 2003-10-06 |
| KR100404390B1 (ko) | 2004-01-31 |
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