ZA966047B - Therapeutic agents. - Google Patents

Therapeutic agents.

Info

Publication number: ZA966047B
Authority: ZA; South Africa
Prior art keywords: therapeutic agents; eicosenoyl; elaidoyl; ara; cis
Prior art date: 1995-07-25

Application number

ZA9606047A

Other languages

English (en)

Inventor

Finn Myhren

Are Dalen

Bernt Borretzen

Kjell Torgeir Stokke

Original Assignee

Norsk Hydro As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-25

Filing date

1996-07-16

Publication date

1997-02-04

1996-07-16 Application filed by Norsk Hydro As filed Critical Norsk Hydro As

1997-02-04 Publication of ZA966047B publication Critical patent/ZA966047B/xx

Links

239000003814 drug Substances 0.000 title 1
229940124597 therapeutic agent Drugs 0.000 title 1
UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical class O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 abstract 1
125000004016 elaidoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
-1 trans-eicosenoyl Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Artificial Filaments (AREA)
Polyamides (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA9606047A 1995-07-25 1996-07-16 Therapeutic agents. ZA966047B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9515279.9A GB9515279D0 (en)	1995-07-25	1995-07-25	Improved therapeutic agents

Publications (1)

Publication Number	Publication Date
ZA966047B true ZA966047B (en)	1997-02-04

Family

ID=10778247

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9606047A ZA966047B (en)	1995-07-25	1996-07-16	Therapeutic agents.

Country Status (25)

Country	Link
US (2)	US6316425B1 (cs)
EP (1)	EP0842185B1 (cs)
JP (2)	JP4372227B2 (cs)
KR (1)	KR100401909B1 (cs)
AT (1)	ATE207076T1 (cs)
AU (1)	AU714814B2 (cs)
CA (1)	CA2227533C (cs)
CZ (1)	CZ291612B6 (cs)
DE (1)	DE69616074T2 (cs)
DK (1)	DK0842185T3 (cs)
ES (1)	ES2166900T3 (cs)
GB (1)	GB9515279D0 (cs)
HU (1)	HU224839B1 (cs)
IL (2)	IL122942A0 (cs)
MX (1)	MX9800622A (cs)
NO (1)	NO313985B1 (cs)
NZ (1)	NZ313790A (cs)
PL (1)	PL183601B1 (cs)
PT (1)	PT842185E (cs)
RU (1)	RU2165260C2 (cs)
SK (1)	SK283003B6 (cs)
TW (1)	TW434251B (cs)
UA (1)	UA55389C2 (cs)
WO (1)	WO1997005154A1 (cs)
ZA (1)	ZA966047B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6458772B1 (en)	1909-10-07	2002-10-01	Medivir Ab	Prodrugs
WO1998021223A1 (en) *	1996-11-12	1998-05-22	Medivir Ab	Nucleosides
CA2278056C (en) *	1997-01-24	2006-12-12	Norsk Hydro Asa	Gemcitabine derivatives
RU2207573C2 (ru) *	2001-08-27	2003-06-27	Новичков Евгений Владимирович	Способ прогнозирования продолжительности жизни больных печеночно-клеточной карциномой
US7393862B2 (en) *	2002-05-17	2008-07-01	Celgene Corporation	Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
JP2007509994A (ja) *	2003-11-03	2007-04-19	コグニス・アイピー・マネージメント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	アシルリボヌクレオシドおよびアシルデオキシリボヌクレオシド
NO324263B1 (no) *	2005-12-08	2007-09-17	Clavis Pharma Asa	Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) *	2005-12-28	2013-07-30	Translational Therapeutics, Inc.	Translational dysfunction based therapeutics
WO2009042767A1 (en) *	2007-09-26	2009-04-02	Mount Sinai School Of Medicine	Azacytidine analogues and uses thereof
GB0808357D0 (en) *	2008-05-08	2008-06-18	Cyclacel Ltd	Process
KR20120086729A (ko) *	2009-11-20	2012-08-03	클라비스 파마 에이에스에이	젬시타빈 유도체의 비경구적 제제
US8912162B2 (en)	2010-07-13	2014-12-16	Clavis Pharma Asa	Parenteral formulations of elacytarabine derivatives
SG10201603288XA (en) *	2012-03-28	2016-05-30	Fujifilm Corp	Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine
GB2571849B (en)	2018-01-15	2020-05-20	Yinuoke Medicine Science And Tech Company Ltd	Treatments for cachexia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3894000A (en) *	1971-01-27	1975-07-08	Upjohn Co	Ara-cytidine derivatives and process of preparation
US4771056A (en) *	1985-08-29	1988-09-13	Roman Rozencwaig	Method of medical treatment with serotonin antagonists
FI105556B (fi)	1991-09-30	2000-09-15	Sankyo Co	Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta
GB2266525A (en) *	1992-03-17	1993-11-03	Merck & Co Inc	Substituted cephalosporin sulfone compositions useful in the treatment of leukemia
GB9307043D0 (en) *	1993-04-05	1993-05-26	Norsk Hydro As	Chemical compounds
US5641758A (en)	1993-11-10	1997-06-24	Kluge; Michael	Cytarabine derivatives, the preparation and use thereof

1995
- 1995-07-25 GB GBGB9515279.9A patent/GB9515279D0/en active Pending
1996
- 1996-07-12 EP EP96926032A patent/EP0842185B1/en not_active Expired - Lifetime
- 1996-07-12 RU RU98103238/04A patent/RU2165260C2/ru not_active IP Right Cessation
- 1996-07-12 JP JP50750497A patent/JP4372227B2/ja not_active Expired - Fee Related
- 1996-07-12 PL PL96324690A patent/PL183601B1/pl not_active IP Right Cessation
- 1996-07-12 CZ CZ1998163A patent/CZ291612B6/cs not_active IP Right Cessation
- 1996-07-12 AU AU66335/96A patent/AU714814B2/en not_active Ceased
- 1996-07-12 NZ NZ313790A patent/NZ313790A/xx not_active IP Right Cessation
- 1996-07-12 US US08/983,483 patent/US6316425B1/en not_active Expired - Lifetime
- 1996-07-12 KR KR10-1998-0700463A patent/KR100401909B1/ko not_active Expired - Fee Related
- 1996-07-12 WO PCT/NO1996/000179 patent/WO1997005154A1/en not_active Ceased
- 1996-07-12 IL IL12294296A patent/IL122942A0/xx active IP Right Grant
- 1996-07-12 AT AT96926032T patent/ATE207076T1/de active
- 1996-07-12 DK DK96926032T patent/DK0842185T3/da active
- 1996-07-12 CA CA002227533A patent/CA2227533C/en not_active Expired - Fee Related
- 1996-07-12 HU HU9900924A patent/HU224839B1/hu not_active IP Right Cessation
- 1996-07-12 DE DE69616074T patent/DE69616074T2/de not_active Expired - Lifetime
- 1996-07-12 ES ES96926032T patent/ES2166900T3/es not_active Expired - Lifetime
- 1996-07-12 PT PT96926032T patent/PT842185E/pt unknown
- 1996-07-12 SK SK80-98A patent/SK283003B6/sk not_active IP Right Cessation
- 1996-07-16 ZA ZA9606047A patent/ZA966047B/xx unknown
- 1996-10-02 TW TW085111996A patent/TW434251B/zh not_active IP Right Cessation
- 1996-12-07 UA UA98020922A patent/UA55389C2/uk unknown
1998
- 1998-01-15 IL IL122942A patent/IL122942A/en not_active IP Right Cessation
- 1998-01-21 MX MX9800622A patent/MX9800622A/es not_active IP Right Cessation
- 1998-01-23 NO NO19980296A patent/NO313985B1/no not_active IP Right Cessation
1999
- 1999-11-09 US US09/435,641 patent/US6335322B1/en not_active Expired - Fee Related
2009
- 2009-07-03 JP JP2009159081A patent/JP5087052B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO980296D0 (no)	1998-01-23
GB9515279D0 (en)	1995-09-20
CA2227533A1 (en)	1997-02-13
JP5087052B2 (ja)	2012-11-28
PT842185E (pt)	2002-04-29
HUP9900924A3 (en)	2001-06-28
JP2002504068A (ja)	2002-02-05
EP0842185B1 (en)	2001-10-17
HUP9900924A2 (hu)	2001-05-28
DE69616074D1 (de)	2001-11-22
CA2227533C (en)	2007-01-09
DK0842185T3 (da)	2002-02-04
AU714814B2 (en)	2000-01-13
ATE207076T1 (de)	2001-11-15
KR19990035804A (ko)	1999-05-25
AU6633596A (en)	1997-02-26
UA55389C2 (uk)	2003-04-15
PL324690A1 (en)	1998-06-08
EP0842185A1 (en)	1998-05-20
CZ16398A3 (cs)	1998-06-17
KR100401909B1 (ko)	2004-02-14
ES2166900T3 (es)	2002-05-01
IL122942A0 (en)	1999-05-09
IL122942A (en)	2006-12-10
CZ291612B6 (cs)	2003-04-16
NZ313790A (en)	1999-07-29
NO980296L (no)	1998-01-23
US6316425B1 (en)	2001-11-13
SK8098A3 (en)	1998-07-08
JP4372227B2 (ja)	2009-11-25
PL183601B1 (pl)	2002-06-28
WO1997005154A1 (en)	1997-02-13
RU2165260C2 (ru)	2001-04-20
HU224839B1 (en)	2006-03-28
JP2009215326A (ja)	2009-09-24
MX9800622A (es)	1998-11-30
DE69616074T2 (de)	2002-06-06
NO313985B1 (no)	2003-01-13
SK283003B6 (sk)	2003-01-09
TW434251B (en)	2001-05-16
US6335322B1 (en)	2002-01-01

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ZA9610650B (en)	1997-06-27	1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
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PL323152A1 (en)	1998-03-16	Derivatives of 1,3-propanodiole as biologically active compounds
ZA965294B (en)	1997-12-22	Substituted 4-phenylaminothiazoles, their process of preparation and the pharmaceutical compositions containing them.
AU5186799A (en)	2000-02-07	Peptides of il-2 and derivatives thereof and their use as therapeutic agents
IL127918A0 (en)	1999-11-30	Novel amino sugar and related sugar derivatives of indolylopyrrolocarbazoles their use as antitumor agents and pharmaceutical formulations
ZA966047B (en)	1997-02-04	Therapeutic agents.
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AU4329396A (en)	1996-07-31	Use of 3,4-diphenylchromans
HUP9700005A3 (en)	1998-07-28	2-ureido-benzamide derivatives and pharmaceutical compositions containing them as active agent
ZA969221B (en)	1998-05-04	Indolealkyl derivatives of benzodioxanmethylamine.
HUP9801880A3 (en)	1999-08-30	Novel cryptophycins, their use and pharmaceutical compositions containing them
ZA965922B (en)	1998-01-12	Preparation of N-substituted 3-hydroxypyrazoles.
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HUP9800631A3 (en)	1998-12-28	4-aminotetrahydrobenzisoxazole or -isothiazole derivatives, pharmaceutical compositions containing them and their use for the preparation of pharmaceutical compositions
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PL325170A1 (en)	1998-07-06	Bipolar forms of throwaflocacin
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HU9700437D0 (en)	1997-04-28	Substituted thiophenyl-alkenyl-carboxylic-acid-guanidid-derivatives, their production, their use as active component of pharmaceutical compositions, and pharmaceutical compositions containing them
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