ZA973708B - Benzofuryl derivatives and their use. - Google Patents

Benzofuryl derivatives and their use.

Info

Publication number: ZA973708B
Authority: ZA; South Africa
Prior art keywords: benzofuryl; derivatives; benzofuryl derivatives
Prior art date: 1996-05-03

Application number

ZA9703708A

Other languages

English (en)

Inventor

Michael Boes

Juergen Wichmann

Heinz Stadler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-03

Filing date

1997-04-29

Publication date

1997-11-03

1997-04-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-11-03 Publication of ZA973708B publication Critical patent/ZA973708B/xx

Links

125000004618 benzofuryl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Addiction (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)

ZA9703708A 1996-05-03 1997-04-29 Benzofuryl derivatives and their use. ZA973708B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP96106990		1996-05-03

Publications (1)

Publication Number	Publication Date
ZA973708B true ZA973708B (en)	1997-11-03

Family

ID=8222741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9703708A ZA973708B (en)	1996-05-03	1997-04-29	Benzofuryl derivatives and their use.

Country Status (21)

Country	Link
US (1)	US5955495A (de)
EP (1)	EP0906301B1 (de)
JP (1)	JP3148253B2 (de)
KR (1)	KR100343060B1 (de)
CN (1)	CN100347164C (de)
AR (1)	AR006915A1 (de)
AT (1)	ATE225342T1 (de)
AU (1)	AU712056B2 (de)
BR (1)	BR9708902A (de)
CA (1)	CA2253547C (de)
CO (1)	CO4940471A1 (de)
DE (1)	DE69716062T2 (de)
DK (1)	DK0906301T3 (de)
ES (1)	ES2182070T3 (de)
HR (1)	HRP970225A2 (de)
MA (1)	MA24168A1 (de)
PE (1)	PE64698A1 (de)
PT (1)	PT906301E (de)
TR (1)	TR199802206T2 (de)
WO (1)	WO1997042183A1 (de)
ZA (1)	ZA973708B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2786184B1 (fr) *	1998-11-24	2002-09-20	Hoechst Marion Roussel Inc	Nouveaux derives du benzofurane, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
HUP0303316A2 (hu)	2000-12-20	2004-01-28	Bristol-Myers Squibb Pharma Company	Aril- és amino-aril-szubsztituált szerotoninreceptor agonista és antagonista ligandumok és ezeket tartalmazó gyógyszerkészítmények
FR2822463B1 (fr)	2001-03-21	2004-07-30	Lipha	Derives bicycliques de guanidines et leurs applications en therapeutique
WO2003082275A1 (en) *	2002-03-29	2003-10-09	Orion Corporation	Treatment of dependence and dependence related withdrawal symptoms
FR2845992B1 (fr) *	2002-10-16	2005-02-04	Pf Medicament	Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
DE10257357A1 (de) *	2002-12-09	2004-06-24	Bayer Ag	Fluorhaltige Benzaldehyde
US20050261347A1 (en) *	2003-10-24	2005-11-24	Wyeth	Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7435837B2 (en) *	2003-10-24	2008-10-14	Wyeth	Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050215644A1 (en) *	2004-03-19	2005-09-29	Interhealth Nutraceuticals, Inc.	Methods for increasing neurotransmitter levels using hydroxycitric acid
US8685924B2 (en)	2004-08-25	2014-04-01	Takeda Pharmaceutical Company Limited	Preventives/remedies for stress urinary incontinence and method of screening the same
RS52711B (sr)	2005-05-10	2013-08-30	Incyte Corporation	Modulatori indolamin 2,3-dioksigenaze i postupci upotrebe istih
EP1971583B1 (de)	2005-12-20	2015-03-25	Incyte Corporation	N-hydroxyamidinoheterocyclen als modulatoren der indolamin-2,3-dioxygenase
EP2018863B9 (de)	2006-05-16	2015-02-18	Takeda Pharmaceutical Company Limited	Kondensierte, heterocyclische Verbindung und ihre Verwendung
CL2007002650A1 (es)	2006-09-19	2008-02-08	Incyte Corp	Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
WO2008036642A2 (en)	2006-09-19	2008-03-27	Incyte Corporation	N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
JP5354741B2 (ja) *	2007-05-29	2013-11-27	公益財団法人大阪バイオサイエンス研究所	睡眠改善剤
EP2789338A3 (de)	2007-11-15	2015-01-14	Takeda Pharmaceutical Company Limited	Kondensiertes Pyridinderivat und seine Verwendung
PL2315756T3 (pl)	2008-07-08	2015-02-27	Incyte Holdings Corp	1,2,5-oksadiazole jako inhibitory 2,3-dioksygenazy indoloaminy
UY32940A (es) *	2009-10-27	2011-05-31	Bayer Cropscience Ag	Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas
US20120253036A1 (en)	2009-12-11	2012-10-04	Yukinori Nagakura	Agent for treating fibromyalgia
CN104045631A (zh) *	2013-03-13	2014-09-17	无锡万全医药技术有限公司	一种制备5-(4-(4-(5-氰基-1h-吲哚-3-基)丁基)哌嗪-1-基)苯并呋喃-2-甲酰胺的新方法
CN103360374B (zh) *	2013-07-12	2016-03-09	苏州永健生物医药有限公司	维拉唑酮及其盐的合成方法
KR102617531B1 (ko)	2013-11-08	2023-12-27	인사이트 홀딩스 코포레이션	인돌아민 2,3-디옥시게나제 억제제의 합성 방법
US20210052600A1 (en)	2017-12-27	2021-02-25	Takeda Pharmaceutical Company Limited	Therapeutic agents for stress urinary incontinence and incotinence of feces
CN114315773B (zh) *	2020-09-29	2024-01-16	广东东阳光药业股份有限公司	一种哌嗪化合物及其制备方法
EP4687880A1 (de) *	2023-03-31	2026-02-11	Tactogen Inc.	Vorteilhafte fluorbenzofurane zur behandlung von geistesstörungen oder verstärkung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4420476A (en)	1982-05-24	1983-12-13	Averst McKenna & Harrison, Inc.	Benzofuro[3,2-c]pyrazol-3-amine derivatives
DE68901424D1 (de) *	1988-07-05	1992-06-11	Akzo Nv	Verbindungen mit bronchodilatatorischer aktivitaet.
US5026726A (en) *	1989-12-11	1991-06-25	The University Of New Mexico	Gossylic iminolactones and gossylic lactones and their anti-viral activities

1997
- 1997-04-14 US US08/837,140 patent/US5955495A/en not_active Expired - Fee Related
- 1997-04-24 JP JP53947997A patent/JP3148253B2/ja not_active Expired - Fee Related
- 1997-04-24 TR TR1998/02206T patent/TR199802206T2/xx unknown
- 1997-04-24 AT AT97921737T patent/ATE225342T1/de not_active IP Right Cessation
- 1997-04-24 BR BR9708902A patent/BR9708902A/pt not_active IP Right Cessation
- 1997-04-24 EP EP97921737A patent/EP0906301B1/de not_active Expired - Lifetime
- 1997-04-24 WO PCT/EP1997/002092 patent/WO1997042183A1/en not_active Ceased
- 1997-04-24 CA CA002253547A patent/CA2253547C/en not_active Expired - Fee Related
- 1997-04-24 PT PT97921737T patent/PT906301E/pt unknown
- 1997-04-24 KR KR1019980708809A patent/KR100343060B1/ko not_active Expired - Fee Related
- 1997-04-24 DK DK97921737T patent/DK0906301T3/da active
- 1997-04-24 CN CNB971943575A patent/CN100347164C/zh not_active Expired - Fee Related
- 1997-04-24 DE DE69716062T patent/DE69716062T2/de not_active Expired - Fee Related
- 1997-04-24 AU AU27696/97A patent/AU712056B2/en not_active Ceased
- 1997-04-24 ES ES97921737T patent/ES2182070T3/es not_active Expired - Lifetime
- 1997-04-29 ZA ZA9703708A patent/ZA973708B/xx unknown
- 1997-04-30 PE PE1997000334A patent/PE64698A1/es not_active Application Discontinuation
- 1997-04-30 AR ARP970101780A patent/AR006915A1/es not_active Application Discontinuation
- 1997-04-30 CO CO97023102A patent/CO4940471A1/es unknown
- 1997-05-02 HR HR96106990.3A patent/HRP970225A2/xx not_active Application Discontinuation
- 1997-05-02 MA MA24589A patent/MA24168A1/fr unknown

Also Published As

Publication number	Publication date
ES2182070T3 (es)	2003-03-01
ATE225342T1 (de)	2002-10-15
KR20000010708A (ko)	2000-02-25
WO1997042183A1 (en)	1997-11-13
MA24168A1 (fr)	1997-12-31
CA2253547C (en)	2006-10-17
HRP970225A2 (en)	1998-04-30
BR9708902A (pt)	1999-08-03
AU712056B2 (en)	1999-10-28
PE64698A1 (es)	1998-10-27
AR006915A1 (es)	1999-09-29
EP0906301A1 (de)	1999-04-07
DK0906301T3 (da)	2003-02-10
JPH11508283A (ja)	1999-07-21
CN100347164C (zh)	2007-11-07
CA2253547A1 (en)	1997-11-13
AU2769697A (en)	1997-11-26
KR100343060B1 (ko)	2002-09-18
CN1217720A (zh)	1999-05-26
DE69716062T2 (de)	2003-06-18
EP0906301B1 (de)	2002-10-02
PT906301E (pt)	2003-02-28
DE69716062D1 (de)	2002-11-07
US5955495A (en)	1999-09-21
CO4940471A1 (es)	2000-07-24
TR199802206T2 (xx)	2001-12-21
JP3148253B2 (ja)	2001-03-19

Publication	Publication Date	Title
ZA973708B (en)	1997-11-03	Benzofuryl derivatives and their use.
ZA976222B (en)	1998-01-19	N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use.
HRP970680B1 (en)	2002-08-31	New ketobenzamides and their use
HUP0000369A3 (en)	2002-01-28	3-thiocarbamoylpyrazole derivatives and their use as pesticides
IL128800A0 (en)	2000-01-31	4-Heteroylpyrazol derivatives and the use thereof as herbicides
EP1032377A4 (de)	2006-06-14	Substituierte 2-aminoacetamide und anwendung davon
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ZA9711047B (en)	1998-06-22	Formulation and use.
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