ZA976353B - Deformylation of f-met peptides in bacterial expression - Google Patents

Deformylation of f-met peptides in bacterial expression

Info

Publication number
ZA976353B
ZA976353B ZA9706353A ZA976353A ZA976353B ZA 976353 B ZA976353 B ZA 976353B ZA 9706353 A ZA9706353 A ZA 9706353A ZA 976353 A ZA976353 A ZA 976353A ZA 976353 B ZA976353 B ZA 976353B
Authority
ZA
South Africa
Prior art keywords
deformylation
bacterial expression
disclosed
met peptides
peptides
Prior art date
Application number
ZA9706353A
Other languages
English (en)
Inventor
Gregg Bogosian
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of ZA976353B publication Critical patent/ZA976353B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5409—IL-5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA9706353A 1996-07-19 1997-07-17 Deformylation of f-met peptides in bacterial expression ZA976353B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2268796P 1996-07-19 1996-07-19

Publications (1)

Publication Number Publication Date
ZA976353B true ZA976353B (en) 1998-02-03

Family

ID=21810912

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9706353A ZA976353B (en) 1996-07-19 1997-07-17 Deformylation of f-met peptides in bacterial expression

Country Status (12)

Country Link
US (2) US5834243A (fr)
EP (1) EP0917580B1 (fr)
JP (1) JP2000515017A (fr)
KR (1) KR100484602B1 (fr)
CN (1) CN1230994A (fr)
AT (1) ATE256748T1 (fr)
AU (1) AU731039B2 (fr)
BR (1) BR9710501B1 (fr)
CA (1) CA2261016A1 (fr)
DE (1) DE69726868T2 (fr)
WO (1) WO1998003664A1 (fr)
ZA (1) ZA976353B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000515017A (ja) * 1996-07-19 2000-11-14 モンサント カンパニー バクテリア発現系におけるｆ―Ｍｅｔペプチドの脱ホルミル化
US6284878B1 (en) * 1996-08-16 2001-09-04 Smithkline Beecham Corporation def1
US6586578B1 (en) * 1997-05-21 2003-07-01 Smithkline Beecham Corporation Defl
US5962666A (en) * 1997-09-16 1999-10-05 Smithkline Beecham Corporation Deformylase
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
WO2000037486A1 (fr) * 1998-12-22 2000-06-29 Holland Sweetener Company V.O.F. Procede de synthese et d'extraction d'aspartame comprenant une phase de deformylation enzymatique
US6617127B2 (en) 1998-12-22 2003-09-09 Holland Sweetener Company, V.O.F. Synthesis and recovery of aspartame involving enzymatic deformylation step
EP1013663A1 (fr) * 1998-12-22 2000-06-28 Holland Sweetener Company V.O.F. Synthèse et récupération d'aspartame comprenant une étape enzymatique de déformylation
US6797820B2 (en) * 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
GB2365433A (en) * 2000-05-25 2002-02-20 Smithkline Beecham Corp Human peptide deformylase
AU2003243316A1 (en) 2002-05-24 2003-12-12 Nps Allelix Corp. Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
AU2003276835A1 (en) * 2002-05-24 2004-02-16 Restoragen, Inc. Polypeptide cleavage process
HRP20120315T1 (hr) 2003-11-21 2012-05-31 Nps Pharmaceuticals Proizvodnja peptida 2 nalik glukagonu i analoga
WO2025091009A2 (fr) * 2023-10-27 2025-05-01 Sutro Biopharma, Inc. Surexpression de lysozyme chez des cellules hôtes exprimant l'arn polymérase t7
CN118389710B (zh) * 2024-06-28 2024-09-06 南京农业大学 一种与鸡开产日龄性状相关的tdh基因分子标记及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2331784A (en) * 1982-12-10 1984-07-05 Nordisk Insulinlaboratorium Fremgangsmade til fremstilling af modne proteiner ud fra fusionsproteiner, syntetiseret i pro-eller eukaryote celler
JP2000515017A (ja) * 1996-07-19 2000-11-14 モンサント カンパニー バクテリア発現系におけるｆ―Ｍｅｔペプチドの脱ホルミル化

Also Published As

Publication number Publication date
CA2261016A1 (fr) 1998-01-29
ATE256748T1 (de) 2004-01-15
CN1230994A (zh) 1999-10-06
BR9710501A (pt) 1999-08-17
JP2000515017A (ja) 2000-11-14
AU3668997A (en) 1998-02-10
BR9710501B1 (pt) 2009-12-01
EP0917580B1 (fr) 2003-12-17
DE69726868T2 (de) 2004-10-28
US6190902B1 (en) 2001-02-20
AU731039B2 (en) 2001-03-22
KR100484602B1 (ko) 2005-04-20
US5834243A (en) 1998-11-10
DE69726868D1 (de) 2004-01-29
WO1998003664A1 (fr) 1998-01-29
KR20000067927A (ko) 2000-11-25
EP0917580A1 (fr) 1999-05-26

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