BR9710501A - Deformila-Æo de f-met pept¡deos em sistemas de expressÆo bacteriana - Google Patents

Deformila-Æo de f-met pept¡deos em sistemas de expressÆo bacteriana

Info

Publication number: BR9710501A
Authority: BR; Brazil
Prior art keywords: deformylation; expression systems; bacterial expression; met peptides; disclosed
Prior art date: 1996-07-19

Application number

BR9710501A

Other languages

English (en)

Other versions

BR9710501B1 (pt

Inventor

Gregg Bogosian

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-19

Filing date

1997-07-17

Publication date

1999-08-17

1997-07-17 Application filed by Monsanto Co filed Critical Monsanto Co

1999-08-17 Publication of BR9710501A publication Critical patent/BR9710501A/pt

2009-12-01 Publication of BR9710501B1 publication Critical patent/BR9710501B1/pt

Links

230000001580 bacterial effect Effects 0.000 title abstract 2
230000006198 deformylation Effects 0.000 title abstract 2
238000006344 deformylation reaction Methods 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
PYUSHNKNPOHWEZ-YFKPBYRVSA-N N-formyl-L-methionine Chemical compound CSCC[C@@H](C(O)=O)NC=O PYUSHNKNPOHWEZ-YFKPBYRVSA-N 0.000 abstract 1
108010026809 Peptide deformylase Proteins 0.000 abstract 1
230000003292 diminished effect Effects 0.000 abstract 1
230000014759 maintenance of location Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5409—IL-5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Endocrinology (AREA)
Microbiology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)

BRPI9710501-5A 1996-07-19 1997-07-17 método para deformilação de uma proteìna recombinante produzida em uma célula hospedeira bacteriana, célula hospedeira de e. coli e seqüência de vetor. BR9710501B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2268796P	1996-07-19	1996-07-19
PCT/US1997/012458 WO1998003664A1 (en)	1996-07-19	1997-07-17	DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS

Publications (2)

Publication Number	Publication Date
BR9710501A true BR9710501A (pt)	1999-08-17
BR9710501B1 BR9710501B1 (pt)	2009-12-01

Family

ID=21810912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9710501-5A BR9710501B1 (pt)	1996-07-19	1997-07-17	método para deformilação de uma proteìna recombinante produzida em uma célula hospedeira bacteriana, célula hospedeira de e. coli e seqüência de vetor.

Country Status (12)

Country	Link
US (2)	US5834243A (pt)
EP (1)	EP0917580B1 (pt)
JP (1)	JP2000515017A (pt)
KR (1)	KR100484602B1 (pt)
CN (1)	CN1230994A (pt)
AT (1)	ATE256748T1 (pt)
AU (1)	AU731039B2 (pt)
BR (1)	BR9710501B1 (pt)
CA (1)	CA2261016A1 (pt)
DE (1)	DE69726868T2 (pt)
WO (1)	WO1998003664A1 (pt)
ZA (1)	ZA976353B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998003664A1 (en) *	1996-07-19	1998-01-29	Monsanto Company	DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS
US6284878B1 (en) *	1996-08-16	2001-09-04	Smithkline Beecham Corporation	def1
US6586578B1 (en) *	1997-05-21	2003-07-01	Smithkline Beecham Corporation	Defl
US5962666A (en) *	1997-09-16	1999-10-05	Smithkline Beecham Corporation	Deformylase
GB9724627D0 (en) *	1997-11-20	1998-01-21	Genencor Int Bv	Gram positive microorganism formate pathway
EP1013663A1 (en) *	1998-12-22	2000-06-28	Holland Sweetener Company V.O.F.	Synthesis and recovery of aspartame involving enzymatic deformylation step
US6617127B2 (en) *	1998-12-22	2003-09-09	Holland Sweetener Company, V.O.F.	Synthesis and recovery of aspartame involving enzymatic deformylation step
WO2000037486A1 (en) *	1998-12-22	2000-06-29	Holland Sweetener Company V.O.F.	Synthesis and recovery of aspartame involving enzymatic deformylation step
US6797820B2 (en) *	1999-12-17	2004-09-28	Vicuron Pharmaceuticals Inc.	Succinate compounds, compositions and methods of use and preparation
US20020137158A1 (en) *	2000-05-25	2002-09-26	Xiaotong Li	Novel human polypeptide deformylase (PDF)
AU2003243316A1 (en)	2002-05-24	2003-12-12	Nps Allelix Corp.	Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
ATE487486T1 (de) *	2002-05-24	2010-11-15	Medtronic Inc	Polypeptid-spaltungsprozess
ME01366B (me)	2003-11-21	2013-12-20	Nps Allelix Corp	POSTUPAK ZA PROIZVODNJU PEPTIDA 2 NALIK NA GLUKAGON l NJIHOVIH ANALOGA
WO2025091009A2 (en) *	2023-10-27	2025-05-01	Sutro Biopharma, Inc.	Overexpression of lysozyme in t7 rna polymerase-expressing host cells
CN118389710B (zh) *	2024-06-28	2024-09-06	南京农业大学	一种与鸡开产日龄性状相关的tdh基因分子标记及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0127658B1 (en) *	1982-12-10	1987-10-14	Nordisk Gentofte A/S	A process for preparing ripe proteins from fusion proteins, synthetized in pro- or eukaryotic cells
WO1998003664A1 (en) *	1996-07-19	1998-01-29	Monsanto Company	DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS

1997
- 1997-07-17 WO PCT/US1997/012458 patent/WO1998003664A1/en not_active Ceased
- 1997-07-17 EP EP97933523A patent/EP0917580B1/en not_active Expired - Lifetime
- 1997-07-17 AU AU36689/97A patent/AU731039B2/en not_active Ceased
- 1997-07-17 AT AT97933523T patent/ATE256748T1/de not_active IP Right Cessation
- 1997-07-17 CN CN97198027A patent/CN1230994A/zh active Pending
- 1997-07-17 JP JP10507072A patent/JP2000515017A/ja active Pending
- 1997-07-17 DE DE69726868T patent/DE69726868T2/de not_active Expired - Lifetime
- 1997-07-17 BR BRPI9710501-5A patent/BR9710501B1/pt not_active IP Right Cessation
- 1997-07-17 KR KR10-1999-7000391A patent/KR100484602B1/ko not_active Expired - Fee Related
- 1997-07-17 ZA ZA9706353A patent/ZA976353B/xx unknown
- 1997-07-17 US US08/895,939 patent/US5834243A/en not_active Expired - Lifetime
- 1997-07-17 CA CA002261016A patent/CA2261016A1/en not_active Abandoned
1998
- 1998-11-09 US US09/188,820 patent/US6190902B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR20000067927A (ko)	2000-11-25
ATE256748T1 (de)	2004-01-15
DE69726868D1 (de)	2004-01-29
KR100484602B1 (ko)	2005-04-20
US5834243A (en)	1998-11-10
CA2261016A1 (en)	1998-01-29
DE69726868T2 (de)	2004-10-28
AU731039B2 (en)	2001-03-22
EP0917580A1 (en)	1999-05-26
BR9710501B1 (pt)	2009-12-01
US6190902B1 (en)	2001-02-20
CN1230994A (zh)	1999-10-06
AU3668997A (en)	1998-02-10
JP2000515017A (ja)	2000-11-14
EP0917580B1 (en)	2003-12-17
WO1998003664A1 (en)	1998-01-29
ZA976353B (en)	1998-02-03

Legal Events

Date	Code	Title	Description
2006-01-24	B25D	Requested change of name of applicant approved	Owner name: PHARMACIA CORPORATION (US) Free format text: ALTERADO DE: MONSANTO COMPANY
2006-02-07	B25A	Requested transfer of rights approved	Owner name: MONSANTO TECHNOLOGY LLC (US) Free format text: TRANSFERIDO DE: PHARMACIA CORPORATION
2006-10-10	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2007-11-13	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-04-15	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-10-28	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2009-06-16	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2009-12-29	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/12/2009, OBSERVADAS AS CONDICOES LEGAIS.
2013-02-13	B24C	Patent annual fee: request for for restoration	Free format text: REFERENTE A 15A ANUIDADE.
2014-04-22	B24H	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
2020-12-08	B24F	Patent annual fee: publication cancelled	Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2259 DE 22/04/2014 POR TER SIDO INDEVIDA.
2020-12-22	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 15A ANUIDADE.
2021-04-13	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BR9710501A (pt)	1999-08-17	Deformila-Æo de f-met pept¡deos em sistemas de expressÆo bacteriana
ATE160587T1 (de)	1997-12-15	Expression rekombinanter polypeptide mit verbesserter möglichkeit zur reinigung
DK1005526T3 (da)	2011-02-07	Direkte ekspression af peptider i kulturmedium
NZ503850A (en)	2002-12-20	April - a novel protein with growth effects
EA200100447A1 (ru)	2001-10-22	Гибридные белки на основе бета-интерферона и их применение
DE69535147D1 (de)	2006-09-14	Überexpression von säugetier- und virusproteinen
BR9609325A (pt)	1999-05-25	Uso de um polipeptídeo ou proteína com sequência de aminoácidos processos para preparar um produto melhorado e para produzir polipeptídeos ou proteínas recombinantes organismo hospedeiro recombinante de tipo alimentício produto e polipeptídeo ou proteína de tipo alimentício recombinante substancialmente puro ou isolado
ATE317904T1 (de)	2006-03-15	Überexpression von phytase in hefesystemen
DE69535948D1 (de)	2009-06-18	Von wd-40 abstammende peptide und ihre verwendung
WO1998022574A3 (de)	1998-07-09	Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden
Gibson et al.	1982	A collagen-like glycoprotein from elastin-rich tissues
AU6435394A (en)	1994-11-08	Fusion proteins between antigenic amino acid sequences and beta-2-microglobulin
ATE297461T1 (de)	2005-06-15	Reguliertes autokrines wachstum von säugerzellen
WO2000034474A3 (en)	2000-12-28	Growth factor homolog zvegf3
CA2249180A1 (en)	1997-09-25	Methods for recombinant microbial production of bpi-fusion proteins and bpi-derived peptides
AU4415796A (en)	1996-06-26	Production of c-terminal amidated peptides from recombinant protein constructs
CA2273196A1 (en)	1998-06-11	Isolated mammalian monocyte cell genes; related reagents
Hori et al.	1979	Purification of tadpole collagenase and characterization using collagen and synthetic substrates
AU2001231881A1 (en)	2001-07-24	Oligomers of nonpeptide restricted mimetics of dipeptides or tripeptides and theuse thereof in the synthesis of synthetic proteins and polypeptides
WO1999002708A8 (en)	1999-04-01	Fusion proteins comprising sequences derived from bovine if1 atpase inhibitor protein
Rühlmann et al.	1988	Complete amino acid sequence of protein B
AU2957099A (en)	1999-10-18	Novel physiologically active peptides and utilization thereof
DE60023933D1 (en)	2005-12-15	Hybrid-toxine von bacillus thuringiensis
Garcia-Pardo et al.	1984	Primary structure of human plasma fibronectin—characterization of the 6,000 dalton C-terminal fragment containing the interchain disulfide bridges
Haracska et al.	1996	Dissection of the Regulator Complex of theDrosophila26S Protease by Limited Proteolysis