ZA982960B - Preparation process of 1-chlorocarbonyl-4-piperidin-opiperidine or hydrocholoride thereof - Google Patents
Preparation process of 1-chlorocarbonyl-4-piperidin-opiperidine or hydrocholoride thereofInfo
- Publication number
- ZA982960B ZA982960B ZA982960A ZA982960A ZA982960B ZA 982960 B ZA982960 B ZA 982960B ZA 982960 A ZA982960 A ZA 982960A ZA 982960 A ZA982960 A ZA 982960A ZA 982960 B ZA982960 B ZA 982960B
- Authority
- ZA
- South Africa
- Prior art keywords
- chlorocarbonyl
- piperidinopiperidine
- hydrochloride
- trialkylsilyl
- reacting
- Prior art date
Links
- YDNSNQRKIINKPV-UHFFFAOYSA-N 4-piperidin-1-ylpiperidine-1-carbonyl chloride Chemical compound C1CN(C(=O)Cl)CCC1N1CCCCC1 YDNSNQRKIINKPV-UHFFFAOYSA-N 0.000 title abstract 2
- IPVYMXZYXFFDGW-UHFFFAOYSA-N 1-methylpiperidin-4-ol;hydrochloride Chemical compound Cl.CN1CCC(O)CC1 IPVYMXZYXFFDGW-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- -1 trialkylsilyl halide Chemical class 0.000 abstract 2
- QDVBKXJMLILLLB-UHFFFAOYSA-N 1,4'-bipiperidine Chemical compound C1CCCCN1C1CCNCC1 QDVBKXJMLILLLB-UHFFFAOYSA-N 0.000 abstract 1
- VBXXNCHZAMNCBX-UHFFFAOYSA-N 4-piperidin-1-ylpiperidine-1-carbonyl chloride;hydrochloride Chemical compound Cl.C1CN(C(=O)Cl)CCC1N1CCCCC1 VBXXNCHZAMNCBX-UHFFFAOYSA-N 0.000 abstract 1
- AKZWRTCWNXHHFR-PDIZUQLASA-N [(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(5S)-5-benzyl-3-[(2R)-2-carbamoyloxy-2,3-dihydro-1H-inden-1-yl]-4-oxo-3H-pyrrol-5-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate Chemical compound NC(=O)O[C@@H]1Cc2ccccc2C1C1C=N[C@](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@H]2CCOC2)(Cc2ccccc2)C1=O AKZWRTCWNXHHFR-PDIZUQLASA-N 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9093723A JP3046258B2 (ja) | 1997-04-11 | 1997-04-11 | 1−クロロカルボニル−4−ピペリジノピペリジンまたはその塩酸塩の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA982960B true ZA982960B (en) | 1998-10-09 |
Family
ID=14090343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA982960A ZA982960B (en) | 1997-04-11 | 1998-04-07 | Preparation process of 1-chlorocarbonyl-4-piperidin-opiperidine or hydrocholoride thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6147215A (fr) |
| EP (1) | EP0976733B1 (fr) |
| JP (1) | JP3046258B2 (fr) |
| CN (1) | CN1110479C (fr) |
| AT (1) | ATE232517T1 (fr) |
| AU (1) | AU723133B2 (fr) |
| BR (1) | BR9808105B1 (fr) |
| CA (1) | CA2286914C (fr) |
| DE (1) | DE69811358T2 (fr) |
| DK (1) | DK0976733T3 (fr) |
| EA (1) | EA001696B1 (fr) |
| ES (1) | ES2192765T3 (fr) |
| IL (1) | IL132077A (fr) |
| TW (1) | TW419476B (fr) |
| WO (1) | WO1998046568A1 (fr) |
| ZA (1) | ZA982960B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3046258B2 (ja) | 1997-04-11 | 2000-05-29 | 株式会社ヤクルト本社 | 1−クロロカルボニル−4−ピペリジノピペリジンまたはその塩酸塩の製造方法 |
| ES2430375T3 (es) * | 2005-02-08 | 2013-11-20 | Fermion Oy | Procedimiento para la producción de cloruro de [1,4']bipiperidinil-1'-carbonilo o su clorhidrato |
| US8546573B2 (en) * | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| WO2011081546A1 (fr) | 2009-12-30 | 2011-07-07 | Schlumberger Canada Limited | Procédé de consolidation de bouchon de fluide à l'intérieur d'un système de fluide dans des applications de trou d'extraction |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5540754A (en) * | 1978-09-19 | 1980-03-22 | Mitsubishi Electric Corp | Electrodeposition coating |
| JPS6019790A (ja) * | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| JPS6150985A (ja) * | 1984-07-05 | 1986-03-13 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| IE913790A1 (en) * | 1990-10-31 | 1992-05-22 | Smithkline Beecham Corp | SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES |
| JP3046258B2 (ja) | 1997-04-11 | 2000-05-29 | 株式会社ヤクルト本社 | 1−クロロカルボニル−4−ピペリジノピペリジンまたはその塩酸塩の製造方法 |
-
1997
- 1997-04-11 JP JP9093723A patent/JP3046258B2/ja not_active Expired - Fee Related
-
1998
- 1998-03-31 EP EP98911123A patent/EP0976733B1/fr not_active Expired - Lifetime
- 1998-03-31 AU AU65206/98A patent/AU723133B2/en not_active Ceased
- 1998-03-31 EA EA199900926A patent/EA001696B1/ru not_active IP Right Cessation
- 1998-03-31 US US09/402,470 patent/US6147215A/en not_active Expired - Lifetime
- 1998-03-31 DK DK98911123T patent/DK0976733T3/da active
- 1998-03-31 CA CA002286914A patent/CA2286914C/fr not_active Expired - Fee Related
- 1998-03-31 IL IL13207798A patent/IL132077A/en not_active IP Right Cessation
- 1998-03-31 ES ES98911123T patent/ES2192765T3/es not_active Expired - Lifetime
- 1998-03-31 WO PCT/JP1998/001465 patent/WO1998046568A1/fr not_active Ceased
- 1998-03-31 AT AT98911123T patent/ATE232517T1/de active
- 1998-03-31 CN CN98804019A patent/CN1110479C/zh not_active Expired - Fee Related
- 1998-03-31 BR BRPI9808105-5A patent/BR9808105B1/pt not_active IP Right Cessation
- 1998-03-31 DE DE69811358T patent/DE69811358T2/de not_active Expired - Lifetime
- 1998-04-02 TW TW087105000A patent/TW419476B/zh not_active IP Right Cessation
- 1998-04-07 ZA ZA982960A patent/ZA982960B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0976733A1 (fr) | 2000-02-02 |
| EA199900926A1 (ru) | 2000-04-24 |
| EP0976733B1 (fr) | 2003-02-12 |
| JP3046258B2 (ja) | 2000-05-29 |
| BR9808105B1 (pt) | 2008-11-18 |
| IL132077A (en) | 2002-11-10 |
| ATE232517T1 (de) | 2003-02-15 |
| AU723133B2 (en) | 2000-08-17 |
| TW419476B (en) | 2001-01-21 |
| CN1252055A (zh) | 2000-05-03 |
| IL132077A0 (en) | 2001-03-19 |
| CA2286914A1 (fr) | 1998-10-22 |
| JPH10287650A (ja) | 1998-10-27 |
| DK0976733T3 (da) | 2003-03-31 |
| AU6520698A (en) | 1998-11-11 |
| EA001696B1 (ru) | 2001-06-25 |
| EP0976733A4 (fr) | 2001-05-09 |
| CN1110479C (zh) | 2003-06-04 |
| CA2286914C (fr) | 2005-07-26 |
| US6147215A (en) | 2000-11-14 |
| DE69811358D1 (de) | 2003-03-20 |
| WO1998046568A1 (fr) | 1998-10-22 |
| BR9808105A (pt) | 2000-03-08 |
| DE69811358T2 (de) | 2003-10-16 |
| ES2192765T3 (es) | 2003-10-16 |
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