DK0976733T3 - Fremgangsmåde til fremstilling af 1-chlorcarbonyl-4-piperidinopiperidin eller hydrochlorid deraf - Google Patents

Fremgangsmåde til fremstilling af 1-chlorcarbonyl-4-piperidinopiperidin eller hydrochlorid deraf

Info

Publication number: DK0976733T3
Authority: DK; Denmark
Prior art keywords: piperidinopiperidine; hydrochloride; chlorocarbonyl; trialkylsilyl; reacting
Prior art date: 1997-04-11

Application number

DK98911123T

Other languages

English (en)

Inventor

Hiroshi Hirota

Original Assignee

Yakult Honsha Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-11

Filing date

1998-03-31

Publication date

2003-03-31

1998-03-31 Application filed by Yakult Honsha Kk filed Critical Yakult Honsha Kk

2003-03-31 Application granted granted Critical

2003-03-31 Publication of DK0976733T3 publication Critical patent/DK0976733T3/da

Links

VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 3
YDNSNQRKIINKPV-UHFFFAOYSA-N 4-piperidin-1-ylpiperidine-1-carbonyl chloride Chemical compound C1CN(C(=O)Cl)CCC1N1CCCCC1 YDNSNQRKIINKPV-UHFFFAOYSA-N 0.000 title abstract 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
-1 trialkylsilyl halide Chemical class 0.000 abstract 2
QDVBKXJMLILLLB-UHFFFAOYSA-N 1,4'-bipiperidine Chemical compound C1CCCCN1C1CCNCC1 QDVBKXJMLILLLB-UHFFFAOYSA-N 0.000 abstract 1
VBXXNCHZAMNCBX-UHFFFAOYSA-N 4-piperidin-1-ylpiperidine-1-carbonyl chloride;hydrochloride Chemical compound Cl.C1CN(C(=O)Cl)CCC1N1CCCCC1 VBXXNCHZAMNCBX-UHFFFAOYSA-N 0.000 abstract 1
AKZWRTCWNXHHFR-PDIZUQLASA-N [(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(5S)-5-benzyl-3-[(2R)-2-carbamoyloxy-2,3-dihydro-1H-inden-1-yl]-4-oxo-3H-pyrrol-5-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate Chemical compound NC(=O)O[C@@H]1Cc2ccccc2C1C1C=N[C@](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@H]2CCOC2)(Cc2ccccc2)C1=O AKZWRTCWNXHHFR-PDIZUQLASA-N 0.000 abstract 1
229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
239000001569 carbon dioxide Substances 0.000 abstract 1
125000004665 trialkylsilyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

DK98911123T 1997-04-11 1998-03-31 Fremgangsmåde til fremstilling af 1-chlorcarbonyl-4-piperidinopiperidin eller hydrochlorid deraf DK0976733T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP9093723A JP3046258B2 (ja)	1997-04-11	1997-04-11	１−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法
PCT/JP1998/001465 WO1998046568A1 (en)	1997-04-11	1998-03-31	Process for producing 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof

Publications (1)

Publication Number	Publication Date
DK0976733T3 true DK0976733T3 (da)	2003-03-31

Family

ID=14090343

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98911123T DK0976733T3 (da)	1997-04-11	1998-03-31	Fremgangsmåde til fremstilling af 1-chlorcarbonyl-4-piperidinopiperidin eller hydrochlorid deraf

Country Status (16)

Country	Link
US (1)	US6147215A (da)
EP (1)	EP0976733B1 (da)
JP (1)	JP3046258B2 (da)
CN (1)	CN1110479C (da)
AT (1)	ATE232517T1 (da)
AU (1)	AU723133B2 (da)
BR (1)	BR9808105B1 (da)
CA (1)	CA2286914C (da)
DE (1)	DE69811358T2 (da)
DK (1)	DK0976733T3 (da)
EA (1)	EA001696B1 (da)
ES (1)	ES2192765T3 (da)
IL (1)	IL132077A (da)
TW (1)	TW419476B (da)
WO (1)	WO1998046568A1 (da)
ZA (1)	ZA982960B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3046258B2 (ja)	1997-04-11	2000-05-29	株式会社ヤクルト本社	１−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法
ES2430375T3 (es) *	2005-02-08	2013-11-20	Fermion Oy	Procedimiento para la producción de cloruro de [1,4']bipiperidinil-1'-carbonilo o su clorhidrato
US8546573B2 (en) *	2009-11-18	2013-10-01	Cadila Healthcare Limited	Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate
WO2011081546A1 (en)	2009-12-30	2011-07-07	Schlumberger Canada Limited	A method of fluid slug consolidation within a fluid system in downhole applications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5540754A (en) *	1978-09-19	1980-03-22	Mitsubishi Electric Corp	Electrodeposition coating
JPS6019790A (ja) *	1983-07-14	1985-01-31	Yakult Honsha Co Ltd	新規なカンプトテシン誘導体
JPS6150985A (ja) *	1984-07-05	1986-03-13	Yakult Honsha Co Ltd	新規なカンプトテシン誘導体
IE913790A1 (en) *	1990-10-31	1992-05-22	Smithkline Beecham Corp	SUBSTITUTED INDOLIZINO [1,2-b]QUINOLINONES
JP3046258B2 (ja)	1997-04-11	2000-05-29	株式会社ヤクルト本社	１−クロロカルボニル−４−ピペリジノピペリジンまたはその塩酸塩の製造方法

1997
- 1997-04-11 JP JP9093723A patent/JP3046258B2/ja not_active Expired - Fee Related
1998
- 1998-03-31 EP EP98911123A patent/EP0976733B1/en not_active Expired - Lifetime
- 1998-03-31 AU AU65206/98A patent/AU723133B2/en not_active Ceased
- 1998-03-31 EA EA199900926A patent/EA001696B1/ru not_active IP Right Cessation
- 1998-03-31 US US09/402,470 patent/US6147215A/en not_active Expired - Lifetime
- 1998-03-31 DK DK98911123T patent/DK0976733T3/da active
- 1998-03-31 CA CA002286914A patent/CA2286914C/en not_active Expired - Fee Related
- 1998-03-31 IL IL13207798A patent/IL132077A/en not_active IP Right Cessation
- 1998-03-31 ES ES98911123T patent/ES2192765T3/es not_active Expired - Lifetime
- 1998-03-31 WO PCT/JP1998/001465 patent/WO1998046568A1/ja not_active Ceased
- 1998-03-31 AT AT98911123T patent/ATE232517T1/de active
- 1998-03-31 CN CN98804019A patent/CN1110479C/zh not_active Expired - Fee Related
- 1998-03-31 BR BRPI9808105-5A patent/BR9808105B1/pt not_active IP Right Cessation
- 1998-03-31 DE DE69811358T patent/DE69811358T2/de not_active Expired - Lifetime
- 1998-04-02 TW TW087105000A patent/TW419476B/zh not_active IP Right Cessation
- 1998-04-07 ZA ZA982960A patent/ZA982960B/xx unknown

Also Published As

Publication number	Publication date
EP0976733A1 (en)	2000-02-02
EA199900926A1 (ru)	2000-04-24
EP0976733B1 (en)	2003-02-12
JP3046258B2 (ja)	2000-05-29
BR9808105B1 (pt)	2008-11-18
IL132077A (en)	2002-11-10
ATE232517T1 (de)	2003-02-15
AU723133B2 (en)	2000-08-17
TW419476B (en)	2001-01-21
CN1252055A (zh)	2000-05-03
IL132077A0 (en)	2001-03-19
ZA982960B (en)	1998-10-09
CA2286914A1 (en)	1998-10-22
JPH10287650A (ja)	1998-10-27
AU6520698A (en)	1998-11-11
EA001696B1 (ru)	2001-06-25
EP0976733A4 (en)	2001-05-09
CN1110479C (zh)	2003-06-04
CA2286914C (en)	2005-07-26
US6147215A (en)	2000-11-14
DE69811358D1 (de)	2003-03-20
WO1998046568A1 (en)	1998-10-22
BR9808105A (pt)	2000-03-08
DE69811358T2 (de)	2003-10-16
ES2192765T3 (es)	2003-10-16

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