ZA988508B - Novel stereoselective processes for the preparation of gabapentin and anologues thereof - Google Patents

Novel stereoselective processes for the preparation of gabapentin and anologues thereof

Info

Publication number: ZA988508B
Authority: ZA; South Africa
Prior art keywords: gabapentin; preparation; anologues; stereoselective processes; novel stereoselective
Prior art date: 1997-09-18

Application number

ZA988508A

Other languages

English (en)

Inventor

Justin Stephen Bryans

Andrew Ian Morrell

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-18

Filing date

1998-09-17

Publication date

1999-03-30

1998-09-17 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1999-03-30 Publication of ZA988508B publication Critical patent/ZA988508B/xx

Links

UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 3
230000000707 stereoselective effect Effects 0.000 title abstract 2
229960002870 gabapentin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catalysts (AREA)
Silicates, Zeolites, And Molecular Sieves (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Hydrogenated Pyridines (AREA)
Indole Compounds (AREA)

ZA988508A 1997-09-18 1998-09-17 Novel stereoselective processes for the preparation of gabapentin and anologues thereof ZA988508B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5920497P	1997-09-18	1997-09-18

Publications (1)

Publication Number	Publication Date
ZA988508B true ZA988508B (en)	1999-03-30

Family

ID=22021467

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA988508A ZA988508B (en)	1997-09-18	1998-09-17	Novel stereoselective processes for the preparation of gabapentin and anologues thereof

Country Status (20)

Country	Link
US (1)	US6465689B1 (da)
EP (1)	EP1015415B1 (da)
JP (1)	JP3878809B2 (da)
KR (1)	KR100563894B1 (da)
AT (1)	ATE239695T1 (da)
AU (1)	AU752444B2 (da)
BR (1)	BR9812351A (da)
CA (1)	CA2295993C (da)
DE (1)	DE69814420T2 (da)
DK (1)	DK1015415T3 (da)
ES (1)	ES2197493T3 (da)
HU (1)	HUP0004582A3 (da)
IL (2)	IL133782A0 (da)
IS (1)	IS2198B (da)
NO (1)	NO326227B1 (da)
NZ (1)	NZ502786A (da)
PL (1)	PL192180B1 (da)
PT (1)	PT1015415E (da)
WO (1)	WO1999014184A1 (da)
ZA (1)	ZA988508B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10203122A1 (de)	2002-01-25	2003-07-31	Gruenenthal Gmbh	Verfahren zur Herstellung von substituierten Acrylsäureestern bzw. deren Einsatz zur Herstellung von substituierten gamma-Aminosäuren
US7439387B2 (en)	2003-04-21	2008-10-21	Matrix Laboratories Ltd.	Process for the preparation of Gabapentin form-II
US20050187295A1 (en) *	2004-02-19	2005-08-25	Surendra Kalyan	Processes for the preparation of gabapentin
EP2172445A1 (en)	2004-03-17	2010-04-07	Hikal Limited	Cis (z) 4-t-butylgabapentin and its synthesis
US7632864B2 (en)	2004-03-17	2009-12-15	Hikal Ltd.	Gabapentin analogues and process thereof
US7442834B2 (en)	2006-06-12	2008-10-28	Zhejiang Chiral Medicine Chemicals Co., Ltd.	Process suitable for industrial scale production of gabapentin
WO2013190357A1 (en) *	2012-06-18	2013-12-27	Hikal Limited	A process for the preparation of gabapentin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3928182A1 (de) *	1989-08-25	1991-02-28	Goedecke Ag	Verfahren zur herstellung von gabapentin
US5929088A (en)	1996-02-07	1999-07-27	Warner-Lambert Company	Cyclic amino acids as pharmaceutical agents
US6020370A (en)	1996-03-14	2000-02-01	Warner-Lambert Company	Bridged cyclic amino acids as pharmaceutical agents

1998
- 1998-08-11 KR KR1020007002825A patent/KR100563894B1/ko not_active Expired - Fee Related
- 1998-08-11 DE DE69814420T patent/DE69814420T2/de not_active Expired - Fee Related
- 1998-08-11 US US09/445,633 patent/US6465689B1/en not_active Expired - Fee Related
- 1998-08-11 PT PT98939340T patent/PT1015415E/pt unknown
- 1998-08-11 AU AU87791/98A patent/AU752444B2/en not_active Ceased
- 1998-08-11 IL IL13378298A patent/IL133782A0/xx active IP Right Grant
- 1998-08-11 PL PL339296A patent/PL192180B1/pl not_active IP Right Cessation
- 1998-08-11 WO PCT/US1998/016652 patent/WO1999014184A1/en not_active Ceased
- 1998-08-11 EP EP98939340A patent/EP1015415B1/en not_active Expired - Lifetime
- 1998-08-11 CA CA002295993A patent/CA2295993C/en not_active Expired - Fee Related
- 1998-08-11 AT AT98939340T patent/ATE239695T1/de not_active IP Right Cessation
- 1998-08-11 JP JP2000511737A patent/JP3878809B2/ja not_active Expired - Fee Related
- 1998-08-11 BR BR9812351-3A patent/BR9812351A/pt active Search and Examination
- 1998-08-11 DK DK98939340T patent/DK1015415T3/da active
- 1998-08-11 HU HU0004582A patent/HUP0004582A3/hu unknown
- 1998-08-11 NZ NZ502786A patent/NZ502786A/en unknown
- 1998-08-11 ES ES98939340T patent/ES2197493T3/es not_active Expired - Lifetime
- 1998-09-17 ZA ZA988508A patent/ZA988508B/xx unknown
1999
- 1999-12-29 IL IL133782A patent/IL133782A/en not_active IP Right Cessation
2000
- 2000-01-21 IS IS5355A patent/IS2198B/is unknown
- 2000-03-17 NO NO20001404A patent/NO326227B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20010024079A (ko)	2001-03-26
HUP0004582A2 (hu)	2001-05-28
EP1015415B1 (en)	2003-05-07
NO326227B1 (no)	2008-10-20
PL339296A1 (en)	2000-12-04
NZ502786A (en)	2002-05-31
IS2198B (is)	2007-02-15
IL133782A0 (en)	2001-04-30
IL133782A (en)	2006-12-31
CA2295993A1 (en)	1999-03-25
DK1015415T3 (da)	2003-07-21
PT1015415E (pt)	2003-09-30
AU752444B2 (en)	2002-09-19
JP2001516738A (ja)	2001-10-02
DE69814420T2 (de)	2003-11-27
WO1999014184A1 (en)	1999-03-25
NO20001404D0 (no)	2000-03-17
AU8779198A (en)	1999-04-05
US6465689B1 (en)	2002-10-15
JP3878809B2 (ja)	2007-02-07
ES2197493T3 (es)	2004-01-01
IS5355A (is)	2000-05-22
BR9812351A (pt)	2000-09-19
CA2295993C (en)	2004-05-04
ATE239695T1 (de)	2003-05-15
PL192180B1 (pl)	2006-09-29
KR100563894B1 (ko)	2006-03-24
NO20001404L (no)	2000-03-17
HUP0004582A3 (en)	2002-01-28
DE69814420D1 (de)	2003-06-12
EP1015415A1 (en)	2000-07-05

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BG102781A (en)	1999-09-30	Isolated dimer fibroblastactivation protein alpha and its application
IL119890A0 (en)	1997-03-18	Preparation of gabapentin
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CA2284142A1 (en)	1998-09-24	Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
ZA988508B (en)	1999-03-30	Novel stereoselective processes for the preparation of gabapentin and anologues thereof
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AU4300497A (en)	1998-04-02	Process for the manufacture of aliphatic alpha, omega amino nitriles
PL338726A1 (en)	2000-11-20	Improved treatment of hides
AU6849198A (en)	1998-11-24	Neurotrypsin
BG101787A (en)	1998-10-30	Aprotinine options having improved properties
DE59813598D1 (de)	2006-07-27	Enzymatisches Verfahren zur Herstellung von (S)-Cyanhydrinen
BG104707A (en)	2001-04-30	Caspase-8 interacting proteins
YU24000A (sh)	2003-02-28	Polimorfi dofetilida
PL338835A1 (en)	2000-11-20	Optically pure analogues of captotectin, optically pure intermediate compound and processes for obtaining them
AU1867899A (en)	1999-05-24	Piece of jewellery
PL325170A1 (en)	1998-07-06	Bipolar forms of throwaflocacin
GB9722451D0 (en)	1997-12-24	The manufacture of gaskets
BG102937A (en)	1999-09-30	Zona pelucida proteins as contraceptives
SI1015415T1 (en)	2003-08-31	Novel stereoselective processes for the preparation of gabapentin analogues
AU5994796A (en)	1996-12-30	Modified kojibiosides analogues
AU7545998A (en)	1998-12-30	Treatment of osteoporosis
AU4708697A (en)	1999-05-17	Process for the preparation of eberconazol and intermediates thereof
AUPO598197A0 (en)	1997-05-01	Treatment of hides
AU2375297A (en)	1998-10-30	Treatment of hides