AP2008004656A0 - Substituted biphenyl carboxylic acids and derivatives thereof - Google Patents

Substituted biphenyl carboxylic acids and derivatives thereof

Info

Publication number
AP2008004656A0
AP2008004656A0 AP2008004656A AP2008004656A AP2008004656A0 AP 2008004656 A0 AP2008004656 A0 AP 2008004656A0 AP 2008004656 A AP2008004656 A AP 2008004656A AP 2008004656 A AP2008004656 A AP 2008004656A AP 2008004656 A0 AP2008004656 A0 AP 2008004656A0
Authority
AP
ARIPO
Prior art keywords
derivatives
carboxylic acids
substituted biphenyl
biphenyl carboxylic
substituted
Prior art date
Application number
AP2008004656A
Other languages
English (en)
Inventor
Jess Taylor
Francis Wilson
Yan Zhang
Original Assignee
Cellzome Ltd
Orthomcneil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellzome Ltd, Orthomcneil Pharmaceutical Inc filed Critical Cellzome Ltd
Publication of AP2008004656A0 publication Critical patent/AP2008004656A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AP2008004656A 2006-04-21 2007-04-20 Substituted biphenyl carboxylic acids and derivatives thereof AP2008004656A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06112938A EP1849762B1 (fr) 2006-04-21 2006-04-21 Acides biphényl carboxyliques substitués et leurs dérivés
PCT/US2007/067039 WO2007124394A1 (fr) 2006-04-21 2007-04-20 Acides biphényle carboxyliques substitués et leurs dérivés

Publications (1)

Publication Number Publication Date
AP2008004656A0 true AP2008004656A0 (en) 2008-10-31

Family

ID=36688012

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004656A AP2008004656A0 (en) 2006-04-21 2007-04-20 Substituted biphenyl carboxylic acids and derivatives thereof

Country Status (35)

Country Link
US (1) US7557244B2 (fr)
EP (2) EP1849762B1 (fr)
JP (1) JP5479088B2 (fr)
KR (1) KR101542255B1 (fr)
CN (1) CN101687758B (fr)
AP (1) AP2008004656A0 (fr)
AR (1) AR060568A1 (fr)
AU (1) AU2007240335B2 (fr)
BR (1) BRPI0710656A2 (fr)
CA (1) CA2650006C (fr)
CR (2) CR10375A (fr)
CY (1) CY1109399T1 (fr)
DE (1) DE602006007810D1 (fr)
DK (1) DK1849762T3 (fr)
EA (1) EA016129B9 (fr)
ES (2) ES2328616T3 (fr)
GE (1) GEP20115269B (fr)
GT (1) GT200900120A (fr)
IL (2) IL194790A (fr)
MA (1) MA30475B1 (fr)
MX (1) MX2008013445A (fr)
MY (1) MY148953A (fr)
NO (1) NO20084517L (fr)
NZ (1) NZ573000A (fr)
PE (1) PE20080364A1 (fr)
PL (1) PL1849762T3 (fr)
PT (1) PT1849762E (fr)
SI (1) SI1849762T1 (fr)
SM (1) SMP200800061B (fr)
TN (1) TNSN08413A1 (fr)
TW (1) TWI399362B (fr)
UA (1) UA95952C2 (fr)
UY (1) UY30301A1 (fr)
WO (1) WO2007124394A1 (fr)
ZA (1) ZA200809856B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5439381B2 (ja) 2007-10-19 2014-03-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ γ−セクレターゼのピペリジニル及びピペラジニル調節物質
EA018862B1 (ru) * 2007-10-19 2013-11-29 Янссен Фармацевтика, Н.В. МОДУЛЯТОРЫ γ-СЕКРЕТАЗЫ
CN101903334A (zh) * 2007-10-19 2010-12-01 詹森药业有限公司 Gsm中间体
WO2009052334A1 (fr) 2007-10-19 2009-04-23 Janssen Pharmaceutica, N.V. Modulateurs liés au carbone de la γ-sécrétase
US20110092554A1 (en) * 2007-11-19 2011-04-21 Richard Chesworth 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
KR20100135711A (ko) 2007-12-20 2010-12-27 엔비보 파마슈티칼즈, 인코퍼레이티드 사중치환된 벤젠
EP2488031A4 (fr) * 2009-10-16 2014-07-23 Merck Sharp & Dohme Dérivés d'éther diarylique comme inhibiteurs de la gamma-sécrétase n'agissant pas sur la voie notch
US8785481B2 (en) 2010-09-29 2014-07-22 Merck Sharp & Dohme Corp. Ether benzotriazole derivatives
CA2828764A1 (fr) * 2011-03-03 2012-09-07 Treventis Corporation Composes anti-amyloides et procedes
WO2015109109A1 (fr) 2014-01-15 2015-07-23 Forum Pharmaceuticals Inc. Morpholino-pyrimidines fusionnées et leurs procédés d'utilisation
US9802927B2 (en) 2015-06-10 2017-10-31 Denali Therapeutics, Inc. Oxadiazine compounds and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877399A (en) 1994-01-27 1999-03-02 Johns Hopkins University Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
JP3802581B2 (ja) * 1995-03-01 2006-07-26 富山化学工業株式会社 新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤
CA2406383A1 (fr) 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research Agents de reduction de a.beta.42
DE10131899A1 (de) 2001-07-04 2003-02-27 Boehringer Ingelheim Pharma In vitro-Screening-Assay für gamma-Secretase
WO2004002939A2 (fr) * 2002-06-27 2004-01-08 Fujisawa Pharmaceutical Co., Ltd. Derives d'aminoalcool
GB0305918D0 (en) * 2003-03-14 2003-04-23 Glaxo Group Ltd Novel compounds
WO2005110963A1 (fr) * 2004-05-19 2005-11-24 Cellzome Ag Acides (biphenyl-3-yl)-carboxyliques et derives de ceux-ci ainsi que leur utilisation en therapie
GB0416508D0 (en) * 2004-07-23 2004-08-25 Merck Sharp & Dohme Therapeutic agents
TW200621227A (en) * 2004-08-24 2006-07-01 Kissei Pharmaceutical Medicament for preventing or treating fatty liver
JP5155171B2 (ja) * 2005-10-06 2013-02-27 アストラゼネカ・アクチエボラーグ 新規化合物

Also Published As

Publication number Publication date
CR10375A (es) 2009-02-26
EP1849762B1 (fr) 2009-07-15
EP2021314A1 (fr) 2009-02-11
EA200802172A1 (ru) 2009-06-30
TNSN08413A1 (en) 2010-04-14
MX2008013445A (es) 2009-03-10
AU2007240335A1 (en) 2007-11-01
PE20080364A1 (es) 2008-05-16
BRPI0710656A2 (pt) 2011-08-16
NO20084517L (no) 2009-01-13
US7557244B2 (en) 2009-07-07
PL1849762T3 (pl) 2009-12-31
TW200815320A (en) 2008-04-01
UY30301A1 (es) 2007-08-31
JP2009544573A (ja) 2009-12-17
UA95952C2 (ru) 2011-09-26
MY148953A (en) 2013-06-14
ES2328616T3 (es) 2009-11-16
SMP200800061B (it) 2009-07-14
GT200900120A (es) 2009-11-16
CY1109399T1 (el) 2014-07-02
EP1849762A1 (fr) 2007-10-31
CA2650006A1 (fr) 2007-11-01
GEP20115269B (en) 2011-08-25
ES2400530T3 (es) 2013-04-10
AU2007240335B2 (en) 2013-05-02
MA30475B1 (fr) 2009-06-01
DK1849762T3 (da) 2009-10-12
CN101687758B (zh) 2014-05-14
SI1849762T1 (sl) 2009-12-31
ZA200809856B (en) 2009-06-24
WO2007124394A1 (fr) 2007-11-01
KR101542255B1 (ko) 2015-08-06
PT1849762E (pt) 2009-09-16
JP5479088B2 (ja) 2014-04-23
NZ573000A (en) 2011-11-25
EP2021314B1 (fr) 2013-01-23
EA016129B1 (ru) 2012-02-28
SMAP200800061A (it) 2008-11-19
CN101687758A (zh) 2010-03-31
IL194790A (en) 2012-12-31
KR20090024679A (ko) 2009-03-09
AR060568A1 (es) 2008-06-25
EA016129B9 (ru) 2012-06-29
DE602006007810D1 (de) 2009-08-27
IL194852A0 (en) 2009-08-03
CR10451A (es) 2009-03-31
TWI399362B (zh) 2013-06-21
US20070293567A1 (en) 2007-12-20
CA2650006C (fr) 2016-08-23
IL194790A0 (en) 2009-08-03

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