NO20084517L - Substituerte bifenylkarboksylsyrer og derivater derav - Google Patents

Substituerte bifenylkarboksylsyrer og derivater derav

Info

Publication number
NO20084517L
NO20084517L NO20084517A NO20084517A NO20084517L NO 20084517 L NO20084517 L NO 20084517L NO 20084517 A NO20084517 A NO 20084517A NO 20084517 A NO20084517 A NO 20084517A NO 20084517 L NO20084517 L NO 20084517L
Authority
NO
Norway
Prior art keywords
derivatives
carboxylic acids
substituted biphenyl
biphenyl carboxylic
group
Prior art date
Application number
NO20084517A
Other languages
English (en)
Norwegian (no)
Inventor
Chih Yung Ho
Alison Reid
Kathryn Smelt
Valerie Reader
Mihiro Sunose
Svenja Burckhardt
Jeremy Major
Francis Wilson
Richard John Harrison
Remedios Hernandez-Perni
Cyrille Boussard
Jess Taylor
Adeline Leformal
Andrew Cansfield
Yan Zhang
Original Assignee
Cellzome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellzome Ltd filed Critical Cellzome Ltd
Publication of NO20084517L publication Critical patent/NO20084517L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20084517A 2006-04-21 2008-10-27 Substituerte bifenylkarboksylsyrer og derivater derav NO20084517L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06112938A EP1849762B1 (fr) 2006-04-21 2006-04-21 Acides biphényl carboxyliques substitués et leurs dérivés
PCT/US2007/067039 WO2007124394A1 (fr) 2006-04-21 2007-04-20 Acides biphényle carboxyliques substitués et leurs dérivés

Publications (1)

Publication Number Publication Date
NO20084517L true NO20084517L (no) 2009-01-13

Family

ID=36688012

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084517A NO20084517L (no) 2006-04-21 2008-10-27 Substituerte bifenylkarboksylsyrer og derivater derav

Country Status (35)

Country Link
US (1) US7557244B2 (fr)
EP (2) EP1849762B1 (fr)
JP (1) JP5479088B2 (fr)
KR (1) KR101542255B1 (fr)
CN (1) CN101687758B (fr)
AP (1) AP2008004656A0 (fr)
AR (1) AR060568A1 (fr)
AU (1) AU2007240335B2 (fr)
BR (1) BRPI0710656A2 (fr)
CA (1) CA2650006C (fr)
CR (2) CR10375A (fr)
CY (1) CY1109399T1 (fr)
DE (1) DE602006007810D1 (fr)
DK (1) DK1849762T3 (fr)
EA (1) EA016129B9 (fr)
ES (2) ES2328616T3 (fr)
GE (1) GEP20115269B (fr)
GT (1) GT200900120A (fr)
IL (2) IL194790A (fr)
MA (1) MA30475B1 (fr)
MX (1) MX2008013445A (fr)
MY (1) MY148953A (fr)
NO (1) NO20084517L (fr)
NZ (1) NZ573000A (fr)
PE (1) PE20080364A1 (fr)
PL (1) PL1849762T3 (fr)
PT (1) PT1849762E (fr)
SI (1) SI1849762T1 (fr)
SM (1) SMP200800061B (fr)
TN (1) TNSN08413A1 (fr)
TW (1) TWI399362B (fr)
UA (1) UA95952C2 (fr)
UY (1) UY30301A1 (fr)
WO (1) WO2007124394A1 (fr)
ZA (1) ZA200809856B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201070497A1 (ru) * 2007-10-19 2010-12-30 Янссен Фармацевтика, Н.В. Промежуточные продукты мгс
ATE543799T1 (de) 2007-10-19 2012-02-15 Janssen Pharmaceutica Nv Piperidinyl- und piperazinylmodulatoren von g- sekretase
EP2212277B1 (fr) * 2007-10-19 2016-08-31 Janssen Pharmaceutica, N.V. Modulateurs de la g-secrétase liés à une amine
US8692017B2 (en) 2007-10-19 2014-04-08 Janssen Pharmaceutica, N.V. Carbon linked modulators of gamma-secretase
US20110092554A1 (en) * 2007-11-19 2011-04-21 Richard Chesworth 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
WO2009086277A1 (fr) 2007-12-20 2009-07-09 Envivo Pharmaceuticals, Inc. Benzènes tétrasubstitués
US8871796B2 (en) 2009-10-16 2014-10-28 Merck Sharp & Dohme Corp. Diaryl ether derivatives as notch sparing gamma secretase inhibitors
US8785481B2 (en) 2010-09-29 2014-07-22 Merck Sharp & Dohme Corp. Ether benzotriazole derivatives
WO2012119035A1 (fr) * 2011-03-03 2012-09-07 Treventis Corporation Composés anti-amyloïdes et procédés
WO2015109109A1 (fr) 2014-01-15 2015-07-23 Forum Pharmaceuticals Inc. Morpholino-pyrimidines fusionnées et leurs procédés d'utilisation
US9802927B2 (en) 2015-06-10 2017-10-31 Denali Therapeutics, Inc. Oxadiazine compounds and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877399A (en) * 1994-01-27 1999-03-02 Johns Hopkins University Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
JP3802581B2 (ja) * 1995-03-01 2006-07-26 富山化学工業株式会社 新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤
AU5702201A (en) 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
DE10131899A1 (de) 2001-07-04 2003-02-27 Boehringer Ingelheim Pharma In vitro-Screening-Assay für gamma-Secretase
KR100693367B1 (ko) * 2002-06-27 2007-03-12 아스텔라스세이야쿠 가부시키가이샤 아미노알콜 유도체
GB0305918D0 (en) * 2003-03-14 2003-04-23 Glaxo Group Ltd Novel compounds
WO2005110963A1 (fr) * 2004-05-19 2005-11-24 Cellzome Ag Acides (biphenyl-3-yl)-carboxyliques et derives de ceux-ci ainsi que leur utilisation en therapie
GB0416508D0 (en) * 2004-07-23 2004-08-25 Merck Sharp & Dohme Therapeutic agents
JPWO2006022237A1 (ja) * 2004-08-24 2008-05-08 キッセイ薬品工業株式会社 脂肪肝の予防または治療剤
EP1937632A1 (fr) * 2005-10-06 2008-07-02 Astra Zeneca AB Nouveaux composes

Also Published As

Publication number Publication date
SMP200800061B (it) 2009-07-14
DE602006007810D1 (de) 2009-08-27
IL194852A0 (en) 2009-08-03
US20070293567A1 (en) 2007-12-20
CY1109399T1 (el) 2014-07-02
PE20080364A1 (es) 2008-05-16
PL1849762T3 (pl) 2009-12-31
ES2328616T3 (es) 2009-11-16
MX2008013445A (es) 2009-03-10
SI1849762T1 (sl) 2009-12-31
EA016129B9 (ru) 2012-06-29
CR10451A (es) 2009-03-31
AU2007240335B2 (en) 2013-05-02
MA30475B1 (fr) 2009-06-01
TNSN08413A1 (en) 2010-04-14
AP2008004656A0 (en) 2008-10-31
EP1849762B1 (fr) 2009-07-15
JP5479088B2 (ja) 2014-04-23
BRPI0710656A2 (pt) 2011-08-16
AU2007240335A1 (en) 2007-11-01
DK1849762T3 (da) 2009-10-12
EP2021314A1 (fr) 2009-02-11
CN101687758A (zh) 2010-03-31
EA016129B1 (ru) 2012-02-28
EP1849762A1 (fr) 2007-10-31
PT1849762E (pt) 2009-09-16
SMAP200800061A (it) 2008-11-19
EP2021314B1 (fr) 2013-01-23
GEP20115269B (en) 2011-08-25
UY30301A1 (es) 2007-08-31
AR060568A1 (es) 2008-06-25
CA2650006C (fr) 2016-08-23
WO2007124394A1 (fr) 2007-11-01
ES2400530T3 (es) 2013-04-10
IL194790A (en) 2012-12-31
UA95952C2 (ru) 2011-09-26
JP2009544573A (ja) 2009-12-17
TWI399362B (zh) 2013-06-21
US7557244B2 (en) 2009-07-07
CA2650006A1 (fr) 2007-11-01
TW200815320A (en) 2008-04-01
KR101542255B1 (ko) 2015-08-06
CN101687758B (zh) 2014-05-14
EA200802172A1 (ru) 2009-06-30
IL194790A0 (en) 2009-08-03
ZA200809856B (en) 2009-06-24
CR10375A (es) 2009-02-26
KR20090024679A (ko) 2009-03-09
GT200900120A (es) 2009-11-16
MY148953A (en) 2013-06-14
NZ573000A (en) 2011-11-25

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application