AP2728A - Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives - Google Patents

Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives

Info

Publication number: AP2728A
Authority: AP; ARIPO
Prior art keywords: dioxa; bicyclo; octane; triol derivatives; triol
Prior art date: 2008-08-28

Application number

AP2011005616A

Other languages

English (en)

Other versions

AP2011005616A0 (en

Inventor

Benjamin Micah Collman

Vincent Mascitti

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-28

Filing date

2009-08-17

Publication date

2013-08-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41208284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2728(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-08-17 Application filed by Pfizer filed Critical Pfizer

2011-04-30 Publication of AP2011005616A0 publication Critical patent/AP2011005616A0/xx

2013-08-31 Application granted granted Critical

2013-08-31 Publication of AP2728A publication Critical patent/AP2728A/xx

Links

WAFOSDMKSJGJBX-UHFFFAOYSA-N octane-2,3,4-triol Chemical class CCCCC(O)C(O)C(C)O WAFOSDMKSJGJBX-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Emergency Medicine (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AP2011005616A 2008-08-28 2009-08-17 Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives AP2728A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US9247008P	2008-08-28	2008-08-28
US22721209P	2009-07-21	2009-07-21
PCT/IB2009/053626 WO2010023594A1 (en)	2008-08-28	2009-08-17	Dioxa-bicyclo[3.2.1.]octane-2,3,4-triol derivatives

Publications (2)

Publication Number	Publication Date
AP2011005616A0 AP2011005616A0 (en)	2011-04-30
AP2728A true AP2728A (en)	2013-08-31

Family

ID=41208284

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2011005616A AP2728A (en)	2008-08-28	2009-08-17	Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives

Country Status (46)

Country	Link
US (1)	US8080580B2 (el)
EP (1)	EP2334687B9 (el)
JP (1)	JP4825322B1 (el)
KR (2)	KR101338540B1 (el)
CN (2)	CN102149717B (el)
AP (1)	AP2728A (el)
AR (1)	AR073138A1 (el)
AT (1)	ATE540040T1 (el)
AU (1)	AU2009286380B2 (el)
BR (1)	BRPI0918841B8 (el)
CA (1)	CA2733795C (el)
CL (1)	CL2011000394A1 (el)
CO (1)	CO6341636A2 (el)
CR (1)	CR20110077A (el)
CY (2)	CY1112497T1 (el)
DK (1)	DK2334687T5 (el)
DO (1)	DOP2011000058A (el)
EA (1)	EA018492B1 (el)
EC (1)	ECSP11010854A (el)
ES (1)	ES2380408T3 (el)
FR (1)	FR18C1036I2 (el)
GE (1)	GEP20135803B (el)
HN (1)	HN2009001652A (el)
HR (1)	HRP20120104T1 (el)
HU (1)	HUS1800031I1 (el)
IL (2)	IL211226A (el)
LT (1)	LTC2334687I2 (el)
MA (1)	MA32590B1 (el)
ME (1)	ME01285A (el)
MX (1)	MX2011002166A (el)
MY (1)	MY155418A (el)
NI (1)	NI201100043A (el)
NL (1)	NL300943I2 (el)
NO (1)	NO2018019I2 (el)
NZ (1)	NZ591027A (el)
PA (1)	PA8840801A1 (el)
PE (1)	PE20110288A1 (el)
PL (1)	PL2334687T3 (el)
PT (1)	PT2334687E (el)
RS (1)	RS52236B (el)
SI (1)	SI2334687T1 (el)
SV (1)	SV2011003842A (el)
TW (1)	TWI387598B (el)
UY (1)	UY32073A (el)
WO (1)	WO2010023594A1 (el)
ZA (1)	ZA201101341B (el)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102149280B (zh)	2008-07-15	2017-05-24	泰拉科斯有限公司	氘化苄基苯衍生物及其使用方法
DK2496583T3 (en) *	2009-11-02	2015-02-02	Pfizer	Dioxa-bicyclo [3.2.1] octane-2,3,4-triol DERIVATIVES
SG183812A1 (en)	2010-03-19	2012-10-30	Pfizer	2,3 dihydro-1h-inden-1-yl- 2,7-diazaspiro [3.5] nonane derivatives and their use as antagonists or inverse agonists of the ghrelin receptor
CN102372722A (zh) *	2010-08-10	2012-03-14	江苏恒瑞医药股份有限公司	C-芳基葡萄糖苷衍生物、其制备方法及其在医药上的应用
WO2012041898A1 (en)	2010-09-29	2012-04-05	Celon Pharma Sp. Z O.O.	Combination of sglt2 inhibitor and a sugar compound for the treatment of diabetes
PT2632925E (pt)	2010-10-29	2015-09-01	Pfizer	Inibidores de n1/n2-lactama da acetil-coa carboxilase
WO2012109996A1 (zh) *	2011-02-18	2012-08-23	上海璎黎科技有限公司	一种芳基糖苷类化合物及其制备方法和应用
CA2828343A1 (en)	2011-03-04	2012-09-13	The Scripps Research Institute	Edn3-like peptides and uses thereof
RS54526B1 (sr)	2011-04-22	2016-06-30	Pfizer Inc.	Upotreba derivata pirazolospiroketona kao inhibitora acetil-coa karboksilaze
US20130137646A1 (en)	2011-06-03	2013-05-30	Boehringer Ingelheim International Gmbh	Methods of treatment, pharmaceutical compositions and uses thereof
US20140228303A1 (en) *	2011-06-13	2014-08-14	Panacea Biotec Ltd	Novel sglt inhibitors
TWI510491B (zh) *	2011-06-30	2015-12-01	Shanghai Hengrui Pharm Co Ltd	Ｃ－芳基葡萄糖苷衍生物、其製備方法及其在醫藥上的應用
CA2841757A1 (en)	2011-07-15	2013-01-24	Etzer Darout	Gpr 119 modulators
JP5647379B2 (ja)	2011-07-22	2014-12-24	ファイザー・インク	キノリニルグルカゴン受容体モジュレーター
WO2013030713A1 (en)	2011-08-31	2013-03-07	Pfizer Inc.	Hexahydropyrano [3,4-d][1,3] thiazin-2-amine compounds
WO2013038429A2 (en)	2011-09-13	2013-03-21	Panacea Biotec Ltd.	Novel sglt inhibitors
WO2013068439A1 (en)	2011-11-09	2013-05-16	Intervet International B.V.	4-amino-5-oxo-7,8-dihydropyrimido[5, 4 -f] [1, 4] oxazepine compounds as dgat1 inhibitors
SG11201401531RA (en)	2011-11-11	2014-07-30	Pfizer	2-thiopyrimidinones
PE20142164A1 (es)	2012-04-06	2014-12-27	Pfizer	Inhibidores de diacilglicerol aciltransferasa 2
US9193751B2 (en)	2012-04-10	2015-11-24	Theracos, Inc.	Process for the preparation of benzylbenzene SGLT2 inhibitors
US8889730B2 (en)	2012-04-10	2014-11-18	Pfizer Inc.	Indole and indazole compounds that activate AMPK
JP6110937B2 (ja)	2012-05-04	2017-04-05	ファイザー・インク	ＡＰＰ、ＢＡＣＥ１、およびＢＡＣＥ２の阻害剤としての複素環式置換ヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物
CN103570657A (zh) *	2012-07-19	2014-02-12	天津药物研究院	一类含偕二甲基的苯基c-葡萄糖苷衍生物、其制备方法和用途
US9145434B2 (en)	2012-07-26	2015-09-29	Boehringer Ingelheim International Gmbh	Crystalline complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(ss-d-glucopyranos-1-yl)-benzene, methods for its preparation and the use thereof for preparing medicaments
CA2882389A1 (en)	2012-09-20	2014-03-27	Pfizer Inc.	Alkyl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
CN103772449B (zh) *	2012-10-26	2017-12-26	上海阳帆医药科技有限公司	C‑芳基葡萄糖苷衍生物及其制备方法与用途
WO2014086099A1 (zh) *	2012-12-05	2014-06-12	广东东阳光药业有限公司	吡喃葡萄糖基衍生物、其制备方法及其在医药上的应用
JP2016502978A (ja)	2012-12-11	2016-02-01	ファイザー・インク	ＢＡＣＥ１の阻害剤としてのヘキサヒドロピラノ［３，４−ｄ］［１，３］チアジン−２−アミン化合物
EP2933250B1 (en) *	2012-12-17	2017-08-09	Tianjin Institute Of Pharmaceutical Research	Phenyl c-glucoside derivative containing deoxyglucose structure, preparation method and use thereof
CA2893333C (en)	2012-12-19	2017-10-24	Pfizer Inc.	Carbocyclic-and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
CA2897678A1 (en)	2013-02-13	2014-08-21	Pfizer Inc.	Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
US9233981B1 (en)	2013-02-15	2016-01-12	Pfizer Inc.	Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
WO2014159151A1 (en) *	2013-03-14	2014-10-02	Msd International Gmbh	Methods for preparing sglt2 inhibitors
CN104045513A (zh) *	2013-03-14	2014-09-17	爱康药业有限公司	4-取代-1-氯-2-(4-氟苄基)苯及其制备方法和作为中间体在制备抗ii型糖尿病药物中的应用
PT2981269T (pt)	2013-04-04	2023-10-10	Boehringer Ingelheim Vetmedica Gmbh	Tratamento de distúrbios metabólicos em animais equinos
WO2014187365A1 (zh) *	2013-05-24	2014-11-27	四川海思科制药有限公司	氧杂双环衍生物、制备方法及其应用
WO2015027963A1 (zh) *	2013-09-02	2015-03-05	四川海思科制药有限公司	芳环类衍生物、其药物组合物及其应用
EP2895490B1 (en) *	2013-09-27	2016-10-19	Sunshine Lake Pharma Co., Ltd.	Glucopyranosyl derivatives and their uses in medicine
JP6348582B2 (ja)	2013-10-09	2018-06-27	ファイザー・インク	プロスタグランジンｅｐ３受容体の拮抗薬
WO2015051484A1 (en)	2013-10-12	2015-04-16	Theracos, Inc.	Preparation of hydroxy-benzylbenzene derivatives
CN105828815B (zh)	2013-12-17	2020-03-27	勃林格殷格翰动物保健有限公司	猫科动物中代谢紊乱的治疗
PL3485890T3 (pl)	2014-01-23	2023-08-28	Boehringer Ingelheim Vetmedica Gmbh	Inhibitory SGLT2 do leczenia zaburzeń metabolicznych u zwierząt psowatych
SG11201606779RA (en)	2014-03-17	2016-10-28	Pfizer	Diacylglycerol acyltransferase 2 inhibitors for use in the treatment of metabolic and related disorders
KR102662473B1 (ko)	2014-04-01	2024-05-03	베링거잉겔하임베트메디카게엠베하	말과 동물에서 대사 장애의 치료
DK3126330T3 (en)	2014-04-04	2019-04-23	Pfizer	BICYCLE-FUSED HETEROARYL OR ARYL COMPOUNDS AND USE THEREOF AS IRAC4 INHIBITORS
AU2015245260A1 (en)	2014-04-10	2016-10-06	Pfizer Inc.	2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides
WO2015177668A1 (en)	2014-05-19	2015-11-26	Pfizer Inc.	Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of asgpr
CN104017031A (zh) *	2014-06-21	2014-09-03	李友香	降血糖药物和组合物
CN104031098A (zh) *	2014-06-21	2014-09-10	李友香	降糖药物
DK3197429T3 (da)	2014-09-25	2024-08-26	Boehringer Ingelheim Vetmedica Gmbh	Kombinationsbehandling med sglt2-hæmmere og dopaminagonister til forebyggelse af metaboliske lidelser af dyr i hestefamilien
CN105461762B (zh) *	2014-09-27	2018-12-04	广东东阳光药业有限公司	吡喃葡萄糖基衍生物及其在医药上的应用
BR112017005454A2 (pt)	2014-09-30	2017-12-12	Jiangsu Hengrui Medicine Co	composto de l-prolina do inibidor 2 do cotransportador de sódio-glicose, e mono-hidrato e cristal do composto de l-prolina
US10285973B2 (en) *	2014-11-10	2019-05-14	Merck Sharp & Dohme Corp.	SGLT-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease
WO2016092413A1 (en)	2014-12-10	2016-06-16	Pfizer Inc.	Indole and indazole compounds that activate ampk
WO2016103097A1 (en)	2014-12-22	2016-06-30	Pfizer Inc.	Antagonists of prostaglandin ep3 receptor
BR112017022340A2 (pt)	2015-05-05	2018-07-10	Pfizer	2-tiopirimidinonas
EP3303345A4 (en) *	2015-05-25	2019-01-30	Sun Pharmaceutical Industries Ltd	ERTUGLIFOZINE CO-CRYSTALS AND PROCESS FOR PREPARING THEM
EP3303303A1 (en)	2015-05-29	2018-04-11	Pfizer Inc	Novel heterocyclic compounds as inhibitors of vanin-1 enzyme
BR112017026191B1 (pt)	2015-06-17	2023-10-10	Pfizer Inc	Compostos tricíclicos inibidores de fosfodiesterase, sua composição farmacêutica e uso dos mesmos
WO2016203335A1 (en)	2015-06-18	2016-12-22	Pfizer Inc.	Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors
JP2018527337A (ja)	2015-08-13	2018-09-20	ファイザー・インク	二環式縮合ヘテロアリールまたはアリール化合物
EP3858825A1 (en)	2015-08-27	2021-08-04	Pfizer Inc.	Bicyclic-fused heteroaryl compounds as irak4 modulators
WO2017032799A1 (en)	2015-08-27	2017-03-02	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising sglt-2 inhibitors
WO2017037567A1 (en)	2015-09-03	2017-03-09	Pfizer Inc.	Regulators of frataxin
AU2016325665A1 (en)	2015-09-24	2018-03-08	Pfizer Inc.	N-[2-(2-amino-6,6-disubstituted-4, 4a, 5, 6-tetrahydropyrano [3,4-d][1,3] thiazin-8a (8h)-yl) -1, 3-thiazol-4-yl] amides
WO2017051294A1 (en)	2015-09-24	2017-03-30	Pfizer Inc.	N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides useful as bace inhibitors
JP2018531924A (ja)	2015-09-24	2018-11-01	ファイザー・インク	テトラヒドロピラノ［３，４−ｄ］［１，３］オキサジン誘導体、およびｂａｃｅ阻害剤としてのその使用
TN2018000198A1 (en)	2015-12-29	2019-10-04	Pfizer	Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors
NZ743987A (en) *	2016-01-04	2019-10-25	Je Il Pharmaceutical Co Ltd	C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same
CN105646603A (zh) *	2016-03-01	2016-06-08	孙霖	埃格列净晶型a及制备方法
CN105646604A (zh) *	2016-03-01	2016-06-08	孙霖	埃格列净晶型b及制备方法
WO2017155841A1 (en) *	2016-03-11	2017-09-14	Merck Sharp & Dohme Corp.	Methods of treating or reducing the risk of cardiovascular events and related diseases using sglt-2 inhibitors
BR112019000589A2 (pt)	2016-07-14	2019-04-24	Pfizer Inc.	pirimidina carboxamidas como inibidores da enzima vanina-1
WO2018011721A1 (en) *	2016-07-15	2018-01-18	Granules India Limited	Novel polymorphic forms of ((1s,2s,3s,4r,5s))-2,3,4-(tris-benzyloxy)-5-(4-chloro-3-(4-ethoxy-benzyl)phenyl)-6,8-dioxa-bicyclo[3.2.1]oct-1-yl-methanol
AR109179A1 (es)	2016-08-19	2018-11-07	Pfizer	Inhibidores de diacilglicerol aciltransferasa 2
EP3528800A1 (en)	2016-10-19	2019-08-28	Boehringer Ingelheim International GmbH	Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof
CN107382952B (zh) *	2017-07-13	2020-02-28	杭州科巢生物科技有限公司	埃格列净的制备方法及其中间体
US12144811B2 (en)	2017-11-30	2024-11-19	Idorsia Pharmaceuticals Ltd	Combination of a 4-pyrimidinesulfamide derivative with an SGLT-2 inhibitor for the treatment of endothelin related diseases
CN107898764A (zh) *	2017-12-12	2018-04-13	威海贯标信息科技有限公司	一种埃格列净组合物
WO2019133445A1 (en)	2017-12-28	2019-07-04	Inception Ibd, Inc.	Aminothiazoles as inhibitors of vanin-1
CN107857768A (zh) *	2018-01-04	2018-03-30	威海贯标信息科技有限公司	一种埃格列净新晶型
WO2019169988A1 (zh) *	2018-03-06	2019-09-12	广东东阳光药业有限公司	埃格列净的晶型及其制备方法
AU2019254371A1 (en)	2018-04-17	2020-10-08	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
WO2019202149A1 (en)	2018-04-19	2019-10-24	Université Catholique de Louvain	Sglt2 inhibitors for the treatment of neutropenia
EP3810623A1 (en)	2018-06-25	2021-04-28	Pharmathen S.A.	A novel process for the preparation of sglt-2 inhibitors
WO2020026273A1 (en) *	2018-07-31	2020-02-06	Msn Laboratories Private Limited, R&D Center	Solid forms of ertugliflozin free base and solid dispersions comprising ertugliflozin l-pyroglutamic acid.
WO2020039394A1 (en)	2018-08-24	2020-02-27	Novartis Ag	New drug combinations
AU2019329884B2 (en)	2018-08-31	2022-01-27	Pfizer Inc.	Combinations for treatment of NASH/NAFLD and related diseases
WO2020102575A1 (en)	2018-11-16	2020-05-22	Inception Ibd, Inc.	Heterocyclic aminothiazoles and uses thereof
EP4578460A3 (en)	2019-05-20	2025-08-27	Pfizer Inc.	Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases
JP7498199B2 (ja)	2019-06-28	2024-06-11	ファイザー・インク	種々の疾患を処置するために有用なｂｃｋｄｋ阻害剤としての５－（チオフェン－２－イル）－１ｈ－テトラゾール誘導体
TW202115086A (zh)	2019-06-28	2021-04-16	美商輝瑞大藥廠	Bckdk抑制劑
TWI879781B (zh) *	2019-07-10	2025-04-11	大陸商廣東東陽光藥業股份有限公司	吡喃葡萄糖基衍生物及其用途
TWI771766B (zh)	2019-10-04	2022-07-21	美商輝瑞股份有限公司	二醯基甘油醯基轉移酶２抑制劑
WO2021105152A1 (en)	2019-11-28	2021-06-03	Boehringer Ingelheim Vetmedica Gmbh	Use of sglt-2 inhibitors in the drying-off of non-human mammals
CN113330017B (zh) *	2019-12-19	2023-01-31	上海研健新药研发有限公司	一种SGLTs抑制剂的纯化方法及其应用
FI4097099T3 (fi)	2020-02-07	2024-07-30	Gasherbrum Bio Inc	Heterosyklisiä glp-1-agonisteja
BR112022016360A2 (pt)	2020-02-17	2022-10-04	Boehringer Ingelheim Vetmedica Gmbh	Uso de inibidores de sglt-2 para a prevenção e/ou tratamento de doenças cardíacas em felinos
JP2022058085A (ja)	2020-02-24	2022-04-11	ファイザー・インク	ジアシルグリセロールアシルトランスフェラーゼ２阻害剤とアセチル－ＣｏＡカルボキシラーゼ阻害剤との組合せ
US20230201174A1 (en)	2020-04-22	2023-06-29	Bayer Aktiengesellschaft	Combination of finerenone and a sglt2 inhibitor for the treatment and/or prevention of cardiovascular and/or renal diseases
PL4143183T3 (pl)	2020-04-29	2026-03-02	Gasherbrum Bio, Inc.	Heterocykliczni agoniści glp-1
PT4161927T (pt)	2020-06-09	2024-10-08	Pfizer	Compostos de espiro como antagonistas do recetor de melanocortina 4 e utilizações dos mesmos
WO2021260498A1 (en) *	2020-06-22	2021-12-30	Aurobindo Pharma Limited	An improved purification process for the preparation of ertugliflozin and ertugliflozin l-pyroglutamic acid co-crystal
CN114195748B (zh) *	2020-09-17	2023-11-14	上海森辉医药有限公司	一种钠-葡萄糖协同转运蛋白2抑制剂的制备方法
EP4376829A1 (en)	2021-07-28	2024-06-05	Boehringer Ingelheim Vetmedica GmbH	Use of sglt-2 inhibitors for the prevention and/or treatment of cardiac diseases in non-human mammals excluding felines, in particular canines
WO2023006747A1 (en)	2021-07-28	2023-02-02	Boehringer Ingelheim Vetmedica Gmbh	Use of sglt-2 inhibitors for the prevention and/or treatment of renal diseases in non-human mammals
US20240269105A1 (en)	2021-07-28	2024-08-15	Boehringer Ingelheim Vetmedica Gmbh	Use of sglt-2 inhibitors for the prevention and/or treatment of hypertension in non-human mammals
US20250066337A1 (en)	2021-08-26	2025-02-27	Pfizer Inc.	Amorphous Form of (S)-2-(5-((3-Ethoxypyridin-2-YL)Oxy)Pyridin-3-YL)-N-(Tetrahydrofuran-3-YL)Pyrimidine-5-Carboxamide
KR20230060921A (ko)	2021-10-28	2023-05-08	유니셀랩 주식회사	에르투글리플로진의 신규 전구체
MX2024006739A (es)	2021-12-01	2024-06-19	Pfizer	Derivados de acido 3-fenil-1-benzotiofeno-2-carboxilico como inhibidores de alfa cetoacido deshidrogenasa quinasa de cadena ramificada para el tratamiento de diabetes, enfermedad renal, esteatohepatitis no alcoholica (nash) e insuficiencia cardiaca.
CA3241470A1 (en)	2021-12-06	2023-06-15	Pfizer Inc.	Melanocortin 4 receptor antagonists and uses thereof
WO2023169456A1 (en)	2022-03-09	2023-09-14	Gasherbrum Bio , Inc.	Heterocyclic glp-1 agonists
US20250250269A1 (en)	2022-04-14	2025-08-07	Gasherbrum Bio, Inc.	Heterocyclic glp-1 agonists
CA3256728A1 (en)	2022-05-25	2023-11-30	Boehringer Ingelheim Vetmedica Gmbh	AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING SGLT-2 INHIBITORS
EP4598908A1 (en)	2022-10-07	2025-08-13	Pfizer Inc.	Hsd17b13 inhibitors and/or degraders
JP2025535295A (ja)	2022-10-18	2025-10-24	ファイザー・インク	パタチン様ホスホリパーゼドメイン含有タンパク質３（ｐｎｐｌａ３）修飾因子
WO2024118524A1 (en)	2022-11-28	2024-06-06	Cerevel Therapeutics, Llc	Azaindole compounds and their use as phosphodiesterase inhibitors
JP2026501171A (ja)	2022-12-15	2026-01-14	ガシャーブラム・バイオ・インコーポレイテッド	Ｇｌｐ－１アゴニスト活性を有する化合物の塩および固体形態
JP2025541231A (ja)	2022-12-16	2025-12-18	ファイザー・インク	３－フルオロ－４－ヒドロキシベンズアミド含有阻害剤および／または分解剤ならびにそれらの使用
TW202500160A (zh)	2023-03-06	2025-01-01	德商百靈佳殷格翰維美迪加股份有限公司	用於遞送特別是包含一或多種ｓｇｌｔ—２抑制劑之液體醫藥組合物之系統及方法
PE20252756A1 (es)	2023-04-14	2025-12-05	Pfizer	Antagonistas del receptor de polipeptido insulinotropico dependiente de glucosa y usos de estos
WO2024240632A1 (en)	2023-05-24	2024-11-28	Boehringer Ingelheim Vetmedica Gmbh	Combination treatment and/or prevention of cardiac diseases in non-human mammals comprising one or more sglt-2 inhibitors and pimobendan and/or telmisartan
TW202508455A (zh)	2023-05-24	2025-03-01	德商百靈佳殷格翰維美迪加股份有限公司	包含一或多種sglt-2抑制劑及替米沙坦(telmisartan)之非人類哺乳動物之腎臟疾病及/或高血壓之組合治療及/或預防
TW202539633A (zh)	2024-02-01	2025-10-16	美商輝瑞股份有限公司	葡萄糖依賴性促胰島素多肽受體拮抗劑及其用途
WO2025224599A1 (en)	2024-04-22	2025-10-30	Pfizer Inc.	Pyrrolidine-based glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
WO2025224069A1 (en)	2024-04-23	2025-10-30	Bayer Aktiengesellschaft	Co-crystals of finerenone, pecavaptan, and sglt2 inhibitors
WO2026013531A1 (en)	2024-07-10	2026-01-15	Pfizer Inc.	Spiro[2.5]octane compounds
WO2026033382A1 (en)	2024-08-07	2026-02-12	Pfizer Inc.	Heterocyclic glp-1r modulators
WO2026042018A1 (en)	2024-08-21	2026-02-26	Pfizer Inc.	4-{4-[(1-{[4-(propan-2-yl)phenyl]carbamoyl)-d-prolyl)amino]cyclohexyl}benzoic acid derivatives as gipr antagonists for the treatment of diabetes
CN120531728B (zh) *	2025-07-28	2025-09-19	华南农业大学	焦谷氨酸在制备抑制脂肪沉积产品中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1852439A1 (en) *	2005-01-28	2007-11-07	Chugai Seiyaku Kabushiki Kaisha	Spiroketal derivative and use thereof as diabetic medicine
WO2007140191A2 (en) *	2006-05-23	2007-12-06	Theracos, Inc.	Glucose transport inhibitors and methods of use
WO2008013280A1 (en) *	2006-07-27	2008-01-31	Chugai Seiyaku Kabushiki Kaisha	Substituted spiroketal derivative and use thereof as drug for treating diabetes

Family Cites Families (143)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US247705A (en) *		1881-09-27		William a
US486299A (en) *		1892-11-15		John k
US560230A (en) *		1896-05-19		powers
US838442A (en) *	1906-05-31	1906-12-11	Oscar Mietens	Compressed-air railway-train brake.
FR1499439A (fr) *	1966-09-16	1967-10-27	Electrochimie Soc	Nouveau polyol et procédé pour sa préparation
JPS5373598A (en) *	1976-12-11	1978-06-30	Teikoku Chem Ind Corp Ltd	Saccharide derivatives and process for thir preparation
JPS5911600B2 (ja) *	1981-04-30	1984-03-16	理化学研究所	３−アジド−１，６−アンヒドロ−３−デオキシ−２，４−ジ−Ｏ−ベンジル−β−Ｄ−グルコピラノ−ス及びその製造法
NZ214774A (en) *	1986-01-08	1989-10-27	Nz Scientific & Ind Res	Herbicidal and/or plant growth regulatory compositions based on 1,6-anhydro-beta-hexopyranose derivatives and certain of these derivatives
US5041541A (en)	1988-05-05	1991-08-20	The Procter & Gamble Company	Functional sugar substituted with reduced calories
CN1020944C (zh) *	1990-01-30	1993-05-26	阿图尔-费希尔股份公司费希尔厂	紧固件
CA2079544A1 (en) *	1991-10-04	1993-04-05	Adam Weislaw Mazur	Cholesterol lowering compounds
DE4400464A1 (de) *	1994-01-11	1995-07-13	Bayer Ag	Endoparasitizide Mittel
ES2176600T3 (es)	1996-12-26	2002-12-01	Tanabe Seiyaku Co	Derivado de la propiofenona y procedimientos para su preparacion.
US6486299B1 (en)	1998-09-28	2002-11-26	Curagen Corporation	Genes and proteins predictive and therapeutic for stroke, hypertension, diabetes and obesity
US6069238A (en) *	1998-09-30	2000-05-30	Eli Lilly And Company	Spirocyclic C-glycosides
BRPI0013667B8 (pt) *	1999-08-31	2021-05-25	Kissei Pharmaceutical	derivados de glucopiranosiloxipirazol, composições medicinais contendo os mesmos e seus intermediários na produção deles
PH12000002657B1 (en) *	1999-10-12	2006-02-21	Bristol Myers Squibb Co	C-aryl glucoside SGLT2 inhibitors
US6515117B2 (en) *	1999-10-12	2003-02-04	Bristol-Myers Squibb Company	C-aryl glucoside SGLT2 inhibitors and method
WO2001042469A1 (en) *	1999-12-10	2001-06-14	Lexicon Genetics Incorporated	Novel human transporter protein and polynucleotides encoding the same
US6627611B2 (en) *	2000-02-02	2003-09-30	Kotobuki Pharmaceutical Co Ltd	C-glycosides and preparation of thereof as antidiabetic agents
DE10006887A1 (de)	2000-02-16	2001-09-06	Hermann Koepsell	Verbindungen, die die Aktivität oder die Konzentration des Regulatorproteins RS1 verändern
DE10008128A1 (de)	2000-02-22	2001-08-23	Bayer Ag	Endoparasitizide Mittel
CZ20023023A3 (cs) *	2000-03-17	2003-04-16	Kissei Pharmaceutical Co., Ltd.	Glukopyranosyloxybenzylbenzenové deriváty, léčivé směsi obsahující tyto látky a meziprodukty pro přípravu derivátů
US6683056B2 (en) *	2000-03-30	2004-01-27	Bristol-Myers Squibb Company	O-aryl glucoside SGLT2 inhibitors and method
US6555519B2 (en) *	2000-03-30	2003-04-29	Bristol-Myers Squibb Company	O-glucosylated benzamide SGLT2 inhibitors and method
EP1329456B1 (en) *	2000-09-29	2006-08-09	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same
ES2337127T3 (es) *	2000-11-02	2010-04-21	Ajinomoto Co., Inc.	Nuevos derivados de pirazol y remedios contra la diabetes que los contienen.
CA2429833A1 (en) *	2000-11-30	2002-06-06	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
US20020081678A1 (en) *	2000-12-11	2002-06-27	Gennady Merkulov	Isolated nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002053738A1 (fr)	2000-12-28	2002-07-11	Takeda Chemical Industries, Ltd.	Nouvelles proteines et adn correspondant
MXPA03005923A (es) *	2000-12-28	2004-01-26	Kissei Pharmaceuticals Co Ltd	Derivados de glupopiranosiloxipirazol y su uso en medicinas.
TWI255817B (en) *	2001-02-14	2006-06-01	Kissei Pharmaceutical	Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
WO2002068439A1 (fr) *	2001-02-26	2002-09-06	Kissei Pharmaceutical Co., Ltd.	Derives de glycopyranosyloxypyrazole et utilisation medicinale de ceux-ci
US7294618B2 (en) *	2001-02-27	2007-11-13	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxypyrazole derivatives and medicinal use thereof
US6936590B2 (en) *	2001-03-13	2005-08-30	Bristol Myers Squibb Company	C-aryl glucoside SGLT2 inhibitors and method
US20050089955A1 (en) *	2001-03-27	2005-04-28	Fangcheng Gong	Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002080935A1 (en) *	2001-04-04	2002-10-17	Ortho Mcneil Pharmaceutical, Inc.	Combination therapy comprising glucose reabsorption inhibitors and retinoid-x receptor modulators
US20030045553A1 (en) *	2001-04-04	2003-03-06	Bussolari Jacqueline C.	Combination therapy comprising glucose reabsorption inhibitors and PPAR modulators
AU2002338643A1 (en) *	2001-04-10	2002-10-28	Millennium Pharmaceuticals, Inc.	68723, sodium/glucose cotransporter family members and uses therefor
ATE318272T1 (de) *	2001-04-11	2006-03-15	Bristol Myers Squibb Co	Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
JP4292570B2 (ja) *	2001-04-27	2009-07-08	味の素株式会社	Ｎ−置換ピラゾール−ｏ−グリコシド誘導体及びそれらを含有する糖尿病治療薬
EP1400529A4 (en) *	2001-05-30	2007-12-19	Kissei Pharmaceutical	GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL AND INTERMEDIARY USE THEREOF
WO2003000712A1 (en) *	2001-06-20	2003-01-03	Kissei Pharmaceutical Co., Ltd.	Nitrogenous heterocyclic derivative, medicinal composition containing the same, medicinal use thereof, and intermediate therefor
JP4115105B2 (ja)	2001-07-02	2008-07-09	協和醗酵工業株式会社	ピラゾール誘導体
US7082091B2 (en) *	2001-07-31	2006-07-25	Ricoh Company, Ltd.	Information reproducing method judging a multivalued level of a present cell by referring to judged multivalued levels of a preceding cell and an ensuing cell
CN1307190C (zh) *	2002-03-22	2007-03-28	橘生药品工业株式会社	吡喃葡糖基氧代苄基苯衍生物的晶体
US20070059356A1 (en) *	2002-05-31	2007-03-15	Almarsson Oern	Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
DE10225844A1 (de)	2002-06-04	2003-12-18	Lang Florian	sgk und nedd als diagnostische und therapeutische targets
DE10231370B4 (de) *	2002-07-11	2006-04-06	Sanofi-Aventis Deutschland Gmbh	Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
TWI254635B (en) *	2002-08-05	2006-05-11	Yamanouchi Pharma Co Ltd	Azulene derivative and salt thereof
BRPI0313290B1 (pt) *	2002-08-08	2016-12-06	Kissei Pharmaceutical	derivados de pirazol, promedicamento, composição farmacêutica, agentes terapêuticos e uso medicinal
UA77300C2 (en) *	2002-08-09	2006-11-15	Taisho Pharmaceutical Co Ltd	5-thio-?-d-glucopyranoside derivatives and pharmaceutical composition for treating diabetes
DE10237085A1 (de)	2002-08-09	2004-02-19	Bioagency Ag	Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen
JP2004137245A (ja)	2002-08-23	2004-05-13	Kissei Pharmaceut Co Ltd	ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体
US20060063711A1 (en) *	2002-10-29	2006-03-23	Keiji Iwamoto	Use of sglt homolog
JP4651934B2 (ja)	2002-12-04	2011-03-16	キッセイ薬品工業株式会社	ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途
EP1568380A4 (en) *	2002-12-04	2009-10-21	Kissei Pharmaceutical	PREVENTION OR TREATMENT OF DISEASES DUE TO HYPERGLYCEMIA
DE10258007B4 (de) *	2002-12-12	2006-02-09	Sanofi-Aventis Deutschland Gmbh	Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
DE10258008B4 (de) *	2002-12-12	2006-02-02	Sanofi-Aventis Deutschland Gmbh	Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
WO2004058790A1 (ja) *	2002-12-25	2004-07-15	Kissei Pharmaceutical Co., Ltd.	含窒素複素環誘導体、それを含有する医薬組成物およびその医薬用途
JP2006516257A (ja) *	2003-01-03	2006-06-29	ブリストル−マイヤーズ　スクイブ　カンパニー	Ｃ−アリールグルコシドｓｇｌｔ２阻害剤の製造法
CN1771334A (zh)	2003-03-07	2006-05-10	施瑞修德制药公司	用于确定肿瘤对抗肿瘤药剂的治疗的敏感性的方法
PL1609785T3 (pl) *	2003-03-14	2016-07-29	Astellas Pharma Inc	Pochodne c-glikozydowe i ich sole
JP2004300102A (ja) *	2003-03-31	2004-10-28	Kissei Pharmaceut Co Ltd	縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
CN1761676A (zh) *	2003-04-01	2006-04-19	大正制药株式会社	杂芳基5－硫代－β－D－吡喃葡糖苷衍生物及含有该衍生物的糖尿病治疗药
JPWO2004089966A1 (ja)	2003-04-01	2006-07-06	大正製薬株式会社	選択的なヘテロアリール５−チオ−β−Ｄ−アルドヘキソピラノシドの製造法
AU2003902263A0 (en)	2003-05-12	2003-05-29	Fujisawa Pharmaceutical Co., Ltd.	Monosaccharide compounds
JPWO2004106352A1 (ja)	2003-05-29	2006-07-20	大正製薬株式会社	アルドヘキソピラノース中間体の製造法
JP2004359630A (ja)	2003-06-06	2004-12-24	Yamanouchi Pharmaceut Co Ltd	ジフルオロジフェニルメタン誘導体及びその塩
US7576064B2 (en) *	2003-06-20	2009-08-18	Kissei Pharmaceutical Co., Ltd.	Pyrazole derivative, drug composition containing the same and production intermediate therefor
UA86042C2 (en)	2003-08-01	2009-03-25	Янссен Фармацевтика Н.В.	Substituted indazole-o-glucosides
WO2005012326A1 (en) *	2003-08-01	2005-02-10	Tanabe Seiyaku Co., Ltd.	Novel compounds having inhibitory activity against sodium-dependant transporter
US7375090B2 (en) *	2003-08-26	2008-05-20	Boehringer Ingelheim International Gmbh	Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
US7371732B2 (en) *	2003-12-22	2008-05-13	Boehringer Ingelheim International Gmbh	Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture
JP2005247834A (ja)	2004-02-04	2005-09-15	Taisho Pharmaceut Co Ltd	ナトリウム依存性グルコース供輸送体２の活性阻害剤
CA2557269C (en) *	2004-03-04	2012-12-04	Kissei Pharmaceutical Co., Ltd.	Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
US7375113B2 (en) *	2004-03-04	2008-05-20	Kissei Pharmaceutical Co., Ltd.	Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs
NZ549219A (en) *	2004-03-04	2010-08-27	Kissei Pharmaceutical	Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
DE102004012676A1 (de) *	2004-03-16	2005-10-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Glucopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
CA2557801C (en) *	2004-03-16	2013-06-25	Boehringer Ingelheim International Gmbh	Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
EP1731524A4 (en) *	2004-03-31	2009-05-20	Kissei Pharmaceutical	PHENOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE DERIVATIVE, AND ITS MEDICINAL USE
WO2005095372A1 (ja)	2004-03-31	2005-10-13	Kissei Pharmaceutical Co., Ltd.	ナフタレン誘導体、それを含有する医薬組成物及びその医薬用途
WO2005095373A1 (ja)	2004-03-31	2005-10-13	Kissei Pharmaceutical Co., Ltd.	ナフタレン誘導体、それを含有する医薬組成物およびその医薬用途
DE102004028241B4 (de) *	2004-06-11	2007-09-13	Sanofi-Aventis Deutschland Gmbh	Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel
US7393836B2 (en) *	2004-07-06	2008-07-01	Boehringer Ingelheim International Gmbh	D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
US20070293690A1 (en) *	2004-07-08	2007-12-20	Hiroshi Tomiyama	Process for Production of Azulene Derivatives and Intermediates for the Synthesis of the Same
DE102004034690A1 (de) *	2004-07-17	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Methyliden-D-xylopyranosyl-und Oxo-D-xylopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
JP5010918B2 (ja) *	2004-07-21	2012-08-29	キッセイ薬品工業株式会社	肝臓脂肪の異常蓄積に起因する疾患の進展抑制剤
TW200606129A (en) *	2004-07-26	2006-02-16	Chugai Pharmaceutical Co Ltd	Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
WO2006010557A1 (de) *	2004-07-27	2006-02-02	Boehringer Ingelheim International Gmbh	D-glucopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
WO2006018150A1 (de) *	2004-08-11	2006-02-23	Boehringer Ingelheim International Gmbh	D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
AR051446A1 (es) *	2004-09-23	2007-01-17	Bristol Myers Squibb Co	Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
JP2006117651A (ja)	2004-09-27	2006-05-11	Taisho Pharmaceut Co Ltd	Ｓｇｌｔ２の活性阻害剤
CA2581922A1 (en) *	2004-09-29	2006-04-06	Kissei Pharmaceutical Co., Ltd.	1-(.beta.-d-glycopyranosyl)-3-substituted nitrogenous heterocyclic compound, medicinal composition containing the same, and medicinal use thereof
DE102004048388A1 (de) *	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
EP1813611B1 (en) *	2004-11-18	2014-10-01	Kissei Pharmaceutical Co., Ltd.	1-substituted-3- beta-d-glycopyranosylated nitrogenous hetero- cyclic compounds and medicines containing the same
JP2008007405A (ja)	2004-12-07	2008-01-17	Takeda Chem Ind Ltd	カルボキサミド誘導体
TW200635599A (en) *	2004-12-16	2006-10-16	Boehringer Ingelheim Int	Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
TW200637839A (en) *	2005-01-07	2006-11-01	Taisho Pharmaceutical Co Ltd	1-thio-d-glucitol derivatives
AR053329A1 (es)	2005-01-31	2007-05-02	Tanabe Seiyaku Co	Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
EP1849795B1 (en) *	2005-02-15	2011-01-26	Kissei Pharmaceutical Co., Ltd.	1-substituted-7-( -d-glycopyranosyloxy)(aza)indole compound and pharmaceutical containing the same
ATE445608T1 (de) *	2005-02-23	2009-10-15	Boehringer Ingelheim Int	Glucopyranosylsubstituierte ((hetero)arylethynyl- benzyl)-benzenderivative und deren verwendung als inhibitoren des natriumabhängigen glucose- cotransporters typ 2 (sglt2)
EP1874787B1 (en)	2005-04-15	2009-12-30	Boehringer Ingelheim International GmbH	Glucopyranosyl-substituted (heteroaryloxy-benzyl)-benzene derivatives as sglt inhibitors
WO2006108584A2 (en) *	2005-04-15	2006-10-19	Cenix Bioscience Gmbh	Human marker genes and agents for cardiovascular disorders and artherosclerosis
WO2006115137A1 (ja)	2005-04-22	2006-11-02	Kissei Pharmaceutical Co., Ltd.	２－アミノベンズイミダゾール誘導体及びその医薬用途
US20070009615A1 (en)	2005-04-29	2007-01-11	Litao Zhong	Compositions and methods for controlling glucose uptake
UA91546C2 (uk)	2005-05-03	2010-08-10	Бьорінгер Інгельхайм Інтернаціональ Гмбх	КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
US7723309B2 (en)	2005-05-03	2010-05-25	Boehringer Ingelheim International Gmbh	Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
US7772191B2 (en)	2005-05-10	2010-08-10	Boehringer Ingelheim International Gmbh	Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
WO2007000445A1 (en) *	2005-06-29	2007-01-04	Boehringer Ingelheim International Gmbh	Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
TW200726755A (en) *	2005-07-07	2007-07-16	Astellas Pharma Inc	A crystalline choline salt of an azulene derivative
EP1910390B1 (en) *	2005-07-27	2010-05-19	Boehringer Ingelheim International GmbH	Glucopyranosyl-substituted ((hetero)cycloalyklethynyl-benzyl)-benzene derivatives and use thereof as sodium-dependent glucose cotransporter (sglt) inhibitors
WO2007019526A2 (en) *	2005-08-05	2007-02-15	Naturegen, Inc.	Compositions and methods for controlling glucose and lipid uptake from foods
DE602006017566D1 (de) *	2005-08-30	2010-11-25	Boehringer Ingelheim Pharma	Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
ES2358051T3 (es) *	2005-09-08	2011-05-05	Boehringer Ingelheim International Gmbh	Formas cristalinas de 1-cloro-4-(beta-d-glucopiranos-1-il)-2-(4-etinil-bencil)-benceno, métodos para su preparación y su uso para preparar medicamentos.
US20070099237A1 (en) *	2005-10-31	2007-05-03	The Regents Of The University Of Michigan	Reaction co-crystallization of molecular complexes or co-crystals
TWI370818B (en) *	2006-04-05	2012-08-21	Astellas Pharma Inc	Cocrystal of c-glycoside derivative and l-proline
JP2009167103A (ja)	2006-05-02	2009-07-30	Taisho Pharmaceutical Co Ltd	ピラゾリル５−チオグリコシド化合物
JP2009167104A (ja)	2006-05-02	2009-07-30	Taisho Pharmaceutical Co Ltd	フェニル５−チオグリコシド化合物
PE20080697A1 (es) *	2006-05-03	2008-08-05	Boehringer Ingelheim Int	Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
DE102006028862A1 (de)	2006-06-23	2007-12-27	Merck Patent Gmbh	3-Amino-imidazo[1,2-a]pyridinderivate
US7919598B2 (en)	2006-06-28	2011-04-05	Bristol-Myers Squibb Company	Crystal structures of SGLT2 inhibitors and processes for preparing same
CA2655937A1 (en) *	2006-06-29	2008-01-03	Taisho Pharmaceutical Co., Ltd.	C-phenyl 1-thioglucitol compound
JP2008050353A (ja)	2006-07-27	2008-03-06	Mitsubishi Tanabe Pharma Corp	医薬組成物
TWI418556B (zh)	2006-07-27	2013-12-11	Mitsubishi Tanabe Pharma Corp	吲哚衍生物
TWI432446B (zh)	2006-07-27	2014-04-01	Chugai Pharmaceutical Co Ltd	稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
US20080027014A1 (en)	2006-07-28	2008-01-31	Tanabe Seiyaku Co., Ltd.	Novel SGLT inhibitors
TW200817424A (en) *	2006-08-04	2008-04-16	Daiichi Sankyo Co Ltd	Benzylphenyl glucopyranoside derivatives
CN101121148B (zh)	2006-08-08	2010-05-12	中国科学院大连化学物理研究所	一种含分子筛的流化反应催化剂直接成型方法
CN101501115B (zh) *	2006-08-09	2012-11-07	陶氏环球技术有限责任公司	在可控方向上膨胀的多部分可膨胀聚合物组合物
EP2054426A1 (en)	2006-08-15	2009-05-06	Boehringer Ingelheim International GmbH	Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture
JP5372759B2 (ja)	2006-09-21	2013-12-18	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	グルコピラノシル−置換ジフルオロベンジル−ベンゼン誘導体、該化合物を含有する医薬品及びその使用と調製方法
EP2072522A4 (en) *	2006-10-13	2010-01-06	Chugai Pharmaceutical Co Ltd	THIOGLUCOSE SPIRKETAL DERIVATIVE AND ITS USE AS DIABETES THERAPEUTIC
DE102006048728A1 (de)	2006-10-16	2008-04-17	Merck Patent Gmbh	3-Amino-imidazo{1,2-a]pyridinderivate
EP2086991A1 (en)	2006-10-27	2009-08-12	Boehringer Ingelheim International GmbH	CRYSTALLINE FORM OF 4-(ß-D-GLUCOPYRANOS-1-YL)-1-METHYL-2-[4-((S)-TETRAHYDROFURAN-3-YLOXY)-BENZYL]-BENZENE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
US7879806B2 (en)	2006-11-06	2011-02-01	Boehringer Ingelheim International Gmbh	Glucopyranosyl-substituted benzyl-benzonitrile derivates, medicaments containing such compounds, their use and process for their manufacture
WO2008115574A1 (en)	2007-03-21	2008-09-25	Reliant Pharmaceuticals, Inc.	Cb1 antagonist and a dyslipidemic agent and/or metabolic regulator, and methods of making and using same
TW200904454A (en)	2007-03-22	2009-02-01	Bristol Myers Squibb Co	Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
EP2183263B1 (en)	2007-07-26	2011-10-26	Lexicon Pharmaceuticals, Inc.	Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
CL2008002425A1 (es)	2007-08-16	2009-09-11	Boehringer Ingelheim Int	Composición farmacéutica que comprende un inhibidor de sglt2 y 1-(4-metil-quinazolin-2-il)metil-3metil-7-(-2-butin-1-il)-8-(3-(r)-amino-piperidin-1il)-xantina, un inhibidor de dpp iv y su uso para el tratamiento de la obesidad y de la diabetes tipo 1 y 2 y complicaciones de esta.
US7838499B2 (en)	2007-08-23	2010-11-23	Theracos, Inc.	Benzylbenzene derivatives and methods of use
CL2008003653A1 (es)	2008-01-17	2010-03-05	Mitsubishi Tanabe Pharma Corp	Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
CN101503399B (zh) *	2008-02-04	2012-06-27	白鹭医药技术（上海）有限公司	C-芳基葡萄糖苷sglt2抑制剂

2009
- 2009-08-17 AP AP2011005616A patent/AP2728A/xx active
- 2009-08-17 MX MX2011002166A patent/MX2011002166A/es active IP Right Grant
- 2009-08-17 MY MYPI2011000903A patent/MY155418A/en unknown
- 2009-08-17 EA EA201100266A patent/EA018492B1/ru active Protection Beyond IP Right Term
- 2009-08-17 HR HR20120104T patent/HRP20120104T1/hr unknown
- 2009-08-17 PE PE2011000205A patent/PE20110288A1/es active IP Right Grant
- 2009-08-17 WO PCT/IB2009/053626 patent/WO2010023594A1/en not_active Ceased
- 2009-08-17 PL PL09786960T patent/PL2334687T3/pl unknown
- 2009-08-17 ME MEP-2011-45A patent/ME01285A/me unknown
- 2009-08-17 EP EP09786960A patent/EP2334687B9/en active Active
- 2009-08-17 CN CN200980135661.2A patent/CN102149717B/zh active Active
- 2009-08-17 DK DK09786960.6T patent/DK2334687T5/da active
- 2009-08-17 SI SI200930161T patent/SI2334687T1/sl unknown
- 2009-08-17 BR BRPI0918841A patent/BRPI0918841B8/pt active IP Right Grant
- 2009-08-17 CN CN201310128399.7A patent/CN103497199B/zh active Active
- 2009-08-17 KR KR1020117006928A patent/KR101338540B1/ko active Active
- 2009-08-17 RS RS20120084A patent/RS52236B/sr unknown
- 2009-08-17 PT PT09786960T patent/PT2334687E/pt unknown
- 2009-08-17 JP JP2011524489A patent/JP4825322B1/ja active Active
- 2009-08-17 AU AU2009286380A patent/AU2009286380B2/en active Active
- 2009-08-17 GE GEAP200912121A patent/GEP20135803B/en unknown
- 2009-08-17 CA CA2733795A patent/CA2733795C/en active Active
- 2009-08-17 AT AT09786960T patent/ATE540040T1/de active
- 2009-08-17 ES ES09786960T patent/ES2380408T3/es active Active
- 2009-08-17 NZ NZ591027A patent/NZ591027A/xx unknown
- 2009-08-17 KR KR1020137025842A patent/KR101446454B1/ko active Active
- 2009-08-24 US US12/546,306 patent/US8080580B2/en active Active
- 2009-08-26 HN HN2009001652A patent/HN2009001652A/es unknown
- 2009-08-26 AR ARP090103280A patent/AR073138A1/es active IP Right Grant
- 2009-08-26 UY UY0001032073A patent/UY32073A/es active IP Right Grant
- 2009-08-27 PA PA20098840801A patent/PA8840801A1/es unknown
- 2009-08-27 TW TW098128894A patent/TWI387598B/zh active
2011
- 2011-02-09 CR CR20110077A patent/CR20110077A/es unknown
- 2011-02-14 IL IL211226A patent/IL211226A/en active Protection Beyond IP Right Term
- 2011-02-17 SV SV2011003842A patent/SV2011003842A/es unknown
- 2011-02-18 ZA ZA2011/01341A patent/ZA201101341B/en unknown
- 2011-02-21 DO DO2011000058A patent/DOP2011000058A/es unknown
- 2011-02-23 CL CL2011000394A patent/CL2011000394A1/es unknown
- 2011-02-23 CO CO11022222A patent/CO6341636A2/es active IP Right Grant
- 2011-02-24 NI NI201100043A patent/NI201100043A/es unknown
- 2011-02-28 MA MA33651A patent/MA32590B1/fr unknown
- 2011-02-28 EC EC2011010854A patent/ECSP11010854A/es unknown
2012
- 2012-03-15 CY CY20121100280T patent/CY1112497T1/el unknown
2015
- 2015-01-19 IL IL236804A patent/IL236804B/en active IP Right Grant
2018
- 2018-06-26 NO NO2018019C patent/NO2018019I2/no unknown
- 2018-06-27 NL NL300943C patent/NL300943I2/nl unknown
- 2018-07-13 HU HUS1800031C patent/HUS1800031I1/hu unknown
- 2018-08-21 LT LTPA2018510C patent/LTC2334687I2/lt unknown
- 2018-08-24 FR FR18C1036C patent/FR18C1036I2/fr active Active
- 2018-09-03 CY CY2018024C patent/CY2018024I1/el unknown

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1852439A1 (en) *	2005-01-28	2007-11-07	Chugai Seiyaku Kabushiki Kaisha	Spiroketal derivative and use thereof as diabetic medicine
WO2007140191A2 (en) *	2006-05-23	2007-12-06	Theracos, Inc.	Glucose transport inhibitors and methods of use
WO2008013280A1 (en) *	2006-07-27	2008-01-31	Chugai Seiyaku Kabushiki Kaisha	Substituted spiroketal derivative and use thereof as drug for treating diabetes

Also Published As

Publication number	Publication date
AU2009286380A1 (en)	2010-03-04
EP2334687B9 (en)	2012-08-08
HK1156616A1 (en)	2012-06-15
BRPI0918841B8 (pt)	2021-05-25
CN103497199A (zh)	2014-01-08
CN102149717A (zh)	2011-08-10
EA201100266A1 (ru)	2011-10-31
JP2012500842A (ja)	2012-01-12
CA2733795A1 (en)	2010-03-04
LTPA2018510I1 (lt)	2018-09-25
CY2018024I2 (el)	2019-11-27
FR18C1036I1 (el)	2018-10-05
GEP20135803B (en)	2013-04-10
KR101446454B1 (ko)	2014-10-06
HK1193606A1 (en)	2014-09-26
CO6341636A2 (es)	2011-11-21
IL236804B (en)	2019-06-30
ATE540040T1 (de)	2012-01-15
US8080580B2 (en)	2011-12-20
ES2380408T9 (es)	2013-02-22
CN103497199B (zh)	2015-04-29
WO2010023594A1 (en)	2010-03-04
EP2334687B1 (en)	2012-01-04
US20100056618A1 (en)	2010-03-04
ZA201101341B (en)	2011-11-30
BRPI0918841A2 (pt)	2015-12-08
SI2334687T1 (sl)	2012-03-30
AU2009286380A8 (en)	2011-03-17
TW201014863A (en)	2010-04-16
EP2334687A1 (en)	2011-06-22
CY1112497T1 (el)	2015-12-09
HUS1800031I1 (hu)	2018-08-28
CL2011000394A1 (es)	2011-06-17
CR20110077A (es)	2011-03-09
NO2018019I2 (no)	2019-02-19
IL211226A0 (en)	2011-04-28
PT2334687E (pt)	2012-04-13
ME01285A (me)	2013-06-20
SV2011003842A (es)	2011-03-23
PA8840801A1 (es)	2010-04-21
MY155418A (en)	2015-10-15
PE20110288A1 (es)	2011-05-26
RS52236B (sr)	2012-10-31
AU2009286380B2 (en)	2011-09-15
MA32590B1 (fr)	2011-08-01
TWI387598B (zh)	2013-03-01
KR20110045093A (ko)	2011-05-03
IL236804A0 (en)	2015-03-31
HN2009001652A (es)	2012-02-13
NI201100043A (es)	2011-08-05
DOP2011000058A (es)	2011-03-15
EA018492B1 (ru)	2013-08-30
UY32073A (es)	2010-03-26
HRP20120104T1 (hr)	2012-02-29
CA2733795C (en)	2013-12-31
AP2011005616A0 (en)	2011-04-30
KR20130116078A (ko)	2013-10-22
DK2334687T3 (da)	2012-04-16
PL2334687T3 (pl)	2012-05-31
LTC2334687I2 (lt)	2019-09-10
ES2380408T3 (es)	2012-05-11
CY2018024I1 (el)	2019-11-27
KR101338540B1 (ko)	2013-12-06
FR18C1036I2 (fr)	2020-07-24
NZ591027A (en)	2012-11-30
JP4825322B1 (ja)	2011-11-30
NO2018019I1 (no)	2018-06-26
MX2011002166A (es)	2011-04-07
CN102149717B (zh)	2014-05-14
NL300943I2 (nl)	2018-08-07
ECSP11010854A (es)	2011-03-31
IL211226A (en)	2015-02-26
DK2334687T5 (da)	2012-09-10
BRPI0918841B1 (pt)	2019-10-08
AR073138A1 (es)	2010-10-13

Publication	Publication Date	Title
HUS1800031I1 (hu)	2018-08-28	Dioxa-biciklo[3.2.1.]oktán-2,3,4-triol származékok
AP3099A (en)	2015-01-31	Dioxa-bicyclo[3.2.1]octane-2,3,4-triol de derivatives
IL206765A0 (en)	2010-12-30	4,5-dihydro-oxazol-2-yl-amine derivatives
IL213787A0 (en)	2011-07-31	Substituted 5,6-dihydro-6-phenylbenzo[f] isoquinolin-2-amine compounds
IL201973A0 (en)	2010-06-16	3,3-spiroindolinone derivatives
ZA201001434B (en)	2013-08-28	2-aza-bicyclo[3.3.0]octane derivatives
ZA201001797B (en)	2010-11-24	1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
ZA201102315B (en)	2012-06-27	7-piperidinoalkyl-3,4-dihyfroquinolone derivative
SI2356123T1 (sl)	2013-01-31	Piro-5,6-dihidro-4h-2,3,5,10b-tetraaza-benzo(e)azuleni
ZA201008657B (en)	2011-10-26	4,5-dihydro-oxazol-2-yl derivatives
EP2283005A4 (en)	2011-08-31	CISATRACURIUM DERIVATIVES, PREPARATION AND USES THEREOF
IL206666A0 (en)	2010-12-30	N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2-
ZA201005346B (en)	2011-11-30	3,8-diaminotetrahydroquinoline derivative
IL206668A0 (en)	2010-12-30	N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2-
IL219623A0 (en)	2012-07-31	[1,5]-diazocin derivatives
TH0901003856A (th)	2015-12-01	อนุพันธ์ของ ไดออกซา-ไบไซโคล[3.2.1]ออคเทน-2,3,4-ไทรออล
GB0813815D0 (en)	2008-09-03	Corcost Pre 1001,10
IL208987A0 (en)	2011-01-31	Cisatracurium derivatives, preparation and uses thereof
GB0808811D0 (en)	2008-06-18	Algabe 2.1