AP298A - Herpes simplex vaccine comprising HSV Glycoprotein gD and 3 deacylated mono-phosphoryl lipid A. - Google Patents
Herpes simplex vaccine comprising HSV Glycoprotein gD and 3 deacylated mono-phosphoryl lipid A. Download PDFInfo
- Publication number
- AP298A AP298A APAP/P/1992/000368A AP9200368A AP298A AP 298 A AP298 A AP 298A AP 9200368 A AP9200368 A AP 9200368A AP 298 A AP298 A AP 298A
- Authority
- AP
- ARIPO
- Prior art keywords
- rgd2t
- alum
- hsv
- mpl
- glycoprotein
- Prior art date
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9105992A GB9105992D0 (en) | 1991-03-21 | 1991-03-21 | Vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP9200368A0 AP9200368A0 (en) | 1992-04-30 |
| AP298A true AP298A (en) | 1994-01-14 |
Family
ID=10691946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| APAP/P/1992/000368A AP298A (en) | 1991-03-21 | 1992-03-20 | Herpes simplex vaccine comprising HSV Glycoprotein gD and 3 deacylated mono-phosphoryl lipid A. |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6027730A (fr) |
| EP (1) | EP0576478B2 (fr) |
| JP (1) | JP3530526B2 (fr) |
| KR (1) | KR100224329B1 (fr) |
| CN (2) | CN1058191C (fr) |
| AP (1) | AP298A (fr) |
| AT (1) | ATE129160T1 (fr) |
| AU (1) | AU650521B2 (fr) |
| BR (1) | BR9205745A (fr) |
| CA (1) | CA2106492C (fr) |
| CY (1) | CY1936A (fr) |
| CZ (1) | CZ280505B6 (fr) |
| DE (1) | DE69205566T3 (fr) |
| DK (1) | DK0576478T4 (fr) |
| ES (1) | ES2081102T5 (fr) |
| FI (1) | FI107881B (fr) |
| GB (1) | GB9105992D0 (fr) |
| GR (1) | GR3017884T3 (fr) |
| HU (1) | HU218025B (fr) |
| IE (1) | IE69560B1 (fr) |
| IL (1) | IL101290A (fr) |
| MA (1) | MA22471A1 (fr) |
| MX (1) | MX9201245A (fr) |
| MY (1) | MY110086A (fr) |
| NO (1) | NO307499B1 (fr) |
| NZ (1) | NZ242057A (fr) |
| PL (1) | PL170059B1 (fr) |
| PT (1) | PT100262B (fr) |
| SA (1) | SA92120459B1 (fr) |
| SK (1) | SK279190B6 (fr) |
| WO (1) | WO1992016231A1 (fr) |
| YU (1) | YU28392A (fr) |
| ZA (1) | ZA922011B (fr) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
| US6197311B1 (en) | 1991-07-25 | 2001-03-06 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
| GB9202933D0 (en) * | 1992-02-12 | 1992-03-25 | Smithkline Beecham Biolog | Vaccines |
| US6620414B2 (en) | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
| WO1994019013A1 (fr) * | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Compositions de vaccin contre la grippe, contenant un lipide a de monophosphoryle desacyle en position 3-o |
| EP0689454B2 (fr) * | 1993-03-23 | 2005-02-23 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Compositions vaccinales renfermant le lipide a monophosphorylique 3-o desacetyle |
| DE69426077T3 (de) * | 1993-05-25 | 2004-09-02 | Wyeth Holdings Corp. | Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus |
| GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| ES2197217T3 (es) * | 1994-12-28 | 2004-01-01 | University Of Kentucky Research Foundation | Anticuerpo 3h1 monoclonal anti-id-murino. |
| US6949244B1 (en) | 1995-12-20 | 2005-09-27 | The Board Of Trustees Of The University Of Kentucky | Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof |
| US20020041872A1 (en) | 1996-04-12 | 2002-04-11 | Malaya Chatterjee | Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1 |
| US6235280B1 (en) | 1996-04-12 | 2001-05-22 | Malaya Chatterjee | Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1 |
| US6468782B1 (en) | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
| US6274143B1 (en) | 1997-06-13 | 2001-08-14 | Malaya Chatterjee | Methods of delaying development of HMFG-associated tumors using anti-idiotype antibody 11D10 |
| US6355244B1 (en) | 1997-11-17 | 2002-03-12 | University Of Kentucky Research Foundation | Methods and compositions for the treatment of psoriasis |
| GB9819898D0 (en) * | 1998-09-11 | 1998-11-04 | Smithkline Beecham Plc | New vaccine and method of use |
| US6692752B1 (en) * | 1999-09-08 | 2004-02-17 | Smithkline Beecham Biologicals S.A. | Methods of treating human females susceptible to HSV infection |
| DE122007000087I1 (de) | 1998-10-16 | 2008-03-27 | Glaxosmithkline Biolog Sa | Adjuvanzsysteme und impfstoffe |
| US7026155B2 (en) | 1999-02-02 | 2006-04-11 | Regents Of The University Of California | Method of reducing bacterial proliferation |
| EP1104767A1 (fr) | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Dérivés de mono- et disaccharides contenant esters d'acides gras et esters de sulfate |
| US9273326B2 (en) | 2004-04-30 | 2016-03-01 | The Brigham And Women's Hospital, Inc. | Tetracycline-regulated gene expression in HSV-1 vectors |
| JP2008513406A (ja) | 2004-09-22 | 2008-05-01 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| TW200700079A (en) | 2005-03-23 | 2007-01-01 | Glaxosmithkline Biolog Sa | Composition |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| CN103251940A (zh) | 2005-12-22 | 2013-08-21 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
| EP1998802A2 (fr) | 2006-03-30 | 2008-12-10 | GlaxoSmithKline Biologicals S.A. | Composition immunogène |
| MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
| US20090181078A1 (en) * | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| HUE036180T2 (hu) | 2006-09-26 | 2018-06-28 | Infectious Disease Res Inst | Szintetikus adjuvánst tartalmazó vakcina készítmény |
| US9452209B2 (en) | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| MX2009013949A (es) | 2007-06-26 | 2010-05-24 | Glaxosmithkline Biolog Sa | Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae. |
| AU2010249330B2 (en) | 2009-05-22 | 2015-11-05 | Genocea Biosciences Inc. | Vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response |
| HUE031051T2 (en) * | 2009-06-05 | 2017-06-28 | Infectious Disease Res Inst | Synthetic glycopyranosyl lipid adjuvant and vaccine compositions containing it |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US8809047B2 (en) * | 2009-12-21 | 2014-08-19 | The Brigham And Women's Hospital, Inc. | Herpes simplex virus vaccines |
| AU2011336894B2 (en) | 2010-11-24 | 2016-11-17 | Genocea Biosciences, Inc. | Vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response |
| EP2683402B1 (fr) * | 2011-03-11 | 2020-06-24 | Turnstone Limited Partnership | Méthode de vaccination faisant intervenir un inhibiteur d'histone désacétylase |
| EP3632463A1 (fr) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Compositions immunogènes et leurs procédés d'utilisation pour induire des réponses immunitaires humorales et cellulaires |
| WO2013028738A1 (fr) | 2011-08-22 | 2013-02-28 | Nanobio Corporation | Vaccin contre le virus de l'herpès simplex sous forme de nanoémulsion |
| AU2012340712B2 (en) | 2011-11-23 | 2017-09-14 | Genocea Biosciences, Inc. | Nucleic acid vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response |
| SI2850431T1 (en) | 2012-05-16 | 2018-08-31 | Immune Design Corp. | Vaccines for hsv-2 |
| DK2941269T3 (da) | 2013-01-07 | 2021-01-11 | Mucosal Vaccine Tech Llc | Terapeutiske vacciner til behandling af herpes simplex-virus type 2-infektioner |
| EP2986303B1 (fr) | 2013-04-18 | 2020-02-26 | Immune Design Corp. | Monothérapie par gla pour une utilisation dans le traitement du cancer |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| JP2019537555A (ja) | 2016-09-28 | 2019-12-26 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | ヘルペスを処置するための方法および組成物 |
| WO2019152821A1 (fr) | 2018-02-05 | 2019-08-08 | The Brigham And Women's Hospital, Inc. | Virus de l'herpès simplex 2 recombinant exprimant des antigènes de glycoprotéine b et d |
| CA3208643A1 (fr) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Compositions immunogenes de coronavirus, methodes et utilisations de celles-ci |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988002634A1 (fr) * | 1986-10-20 | 1988-04-21 | Chiron Corporation | Vaccin utilise pour le traitement therapeutique de hsv |
| GB2220211A (en) * | 1988-06-29 | 1990-01-04 | Ribi Immunochem Research Inc | Modified lipopolysaccharides |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4372945A (en) * | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| IL61904A (en) * | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| US5110587A (en) * | 1981-12-24 | 1992-05-05 | Health Research, Incorporated | Immunogenic composition comprising synthetically modified vaccinia virus |
| US4762708A (en) * | 1982-02-18 | 1988-08-09 | University Patents, Inc. | Materials and methods for herpes simplex virus vaccination |
| US5149660A (en) * | 1982-02-18 | 1992-09-22 | University Patents, Inc. | Diagnostic reagents relating to herpes simplex virus |
| NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
| US5171568A (en) * | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
| US5244792A (en) * | 1984-04-06 | 1993-09-14 | Chiron Corporation | Expression of recombinant glyoprotein B from herpes simplex virus |
| US4877611A (en) * | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US5554372A (en) * | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US5149529A (en) * | 1988-04-08 | 1992-09-22 | Board Of Trustees Of Leland Chiron Corporation | Compositions and treatment for herpes simplex |
| NZ230424A (en) * | 1988-08-25 | 1992-05-26 | Liposome Co Inc | Liposomal composition comprising an externally disposed antigen |
| JP2955314B2 (ja) * | 1988-10-27 | 1999-10-04 | リージェンツ・オブ・ザ・ユニバーシティー・オブ・ミネソタ | Il―2含有リポソーム免疫アジュバント |
| US5597573A (en) * | 1989-05-04 | 1997-01-28 | Igen, Inc. | Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities |
| US5158939A (en) * | 1989-07-21 | 1992-10-27 | Wisconsin Alumni Research Foundation | Method of stimulating the immune systems of animals and compositions useful therefor |
| FI920131A0 (fi) * | 1989-07-14 | 1992-01-13 | Praxis Biolog Inc | Cytokin- och hormonbaerare foer konjugatvaccin. |
| CA2088246A1 (fr) * | 1990-08-01 | 1992-02-02 | Dennis J. O'callaghan | Gene codant la glycoproteine d du virus herpetique equin de type i, son produit genique, et anticorps de cette glycoproteine et leurs utilisations |
| JP3005292B2 (ja) * | 1990-08-02 | 2000-01-31 | カイロン コーポレイション | 単純ヘルペスウィルスのvp16のワクチン |
| GB9106048D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccines |
| US5166173A (en) * | 1991-01-29 | 1992-11-24 | Genelabs Incorporated | Method of treating herpes simplex virus infection |
| US5196452A (en) * | 1991-01-29 | 1993-03-23 | Genelabs Incorporated | Macrocyclic anti-viral compound and method |
| GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
| MA22842A1 (fr) * | 1992-03-27 | 1993-10-01 | Smithkline Beecham Biolog | Procede de preparation de compositions de vaccin. |
| NZ253137A (en) * | 1992-06-25 | 1996-08-27 | Smithkline Beecham Biolog | Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a. |
| WO1994019013A1 (fr) * | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Compositions de vaccin contre la grippe, contenant un lipide a de monophosphoryle desacyle en position 3-o |
| EP0689454B2 (fr) * | 1993-03-23 | 2005-02-23 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Compositions vaccinales renfermant le lipide a monophosphorylique 3-o desacetyle |
| DE69426077T3 (de) * | 1993-05-25 | 2004-09-02 | Wyeth Holdings Corp. | Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus |
-
1991
- 1991-03-21 GB GB9105992A patent/GB9105992D0/en active Pending
-
1992
- 1992-03-17 AU AU13657/92A patent/AU650521B2/en not_active Expired
- 1992-03-17 PL PL92300617A patent/PL170059B1/pl unknown
- 1992-03-17 ES ES92906441T patent/ES2081102T5/es not_active Expired - Lifetime
- 1992-03-17 CA CA 2106492 patent/CA2106492C/fr not_active Expired - Lifetime
- 1992-03-17 AT AT92906441T patent/ATE129160T1/de active
- 1992-03-17 WO PCT/EP1992/000592 patent/WO1992016231A1/fr not_active Ceased
- 1992-03-17 CY CY193692A patent/CY1936A/xx unknown
- 1992-03-17 JP JP50598492A patent/JP3530526B2/ja not_active Expired - Lifetime
- 1992-03-17 SK SK946-93A patent/SK279190B6/sk unknown
- 1992-03-17 KR KR1019930702835A patent/KR100224329B1/ko not_active Expired - Lifetime
- 1992-03-17 EP EP19920906441 patent/EP0576478B2/fr not_active Expired - Lifetime
- 1992-03-17 HU HU9302645A patent/HU218025B/hu unknown
- 1992-03-17 BR BR9205745A patent/BR9205745A/pt not_active Application Discontinuation
- 1992-03-17 DK DK92906441T patent/DK0576478T4/da active
- 1992-03-17 DE DE69205566T patent/DE69205566T3/de not_active Expired - Lifetime
- 1992-03-17 CZ CS931958A patent/CZ280505B6/cs not_active IP Right Cessation
- 1992-03-18 MY MYPI92000448A patent/MY110086A/en unknown
- 1992-03-19 ZA ZA922011A patent/ZA922011B/xx unknown
- 1992-03-19 IE IE920881A patent/IE69560B1/en not_active IP Right Cessation
- 1992-03-19 IL IL10129092A patent/IL101290A/en not_active IP Right Cessation
- 1992-03-19 PT PT100262A patent/PT100262B/pt not_active IP Right Cessation
- 1992-03-19 NZ NZ242057A patent/NZ242057A/en not_active IP Right Cessation
- 1992-03-19 CN CN92102950A patent/CN1058191C/zh not_active Expired - Lifetime
- 1992-03-19 MA MA22760A patent/MA22471A1/fr unknown
- 1992-03-20 MX MX9201245A patent/MX9201245A/es unknown
- 1992-03-20 YU YU28392A patent/YU28392A/sh unknown
- 1992-03-20 AP APAP/P/1992/000368A patent/AP298A/en active
- 1992-04-21 SA SA92120459A patent/SA92120459B1/ar unknown
-
1993
- 1993-09-20 NO NO933343A patent/NO307499B1/no not_active IP Right Cessation
- 1993-09-21 FI FI934134A patent/FI107881B/fi not_active IP Right Cessation
-
1994
- 1994-09-09 US US08/303,542 patent/US6027730A/en not_active Expired - Lifetime
-
1995
- 1995-10-25 GR GR950402992T patent/GR3017884T3/el unknown
-
1998
- 1998-01-05 CN CN98103933A patent/CN1101226C/zh not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988002634A1 (fr) * | 1986-10-20 | 1988-04-21 | Chiron Corporation | Vaccin utilise pour le traitement therapeutique de hsv |
| GB2220211A (en) * | 1988-06-29 | 1990-01-04 | Ribi Immunochem Research Inc | Modified lipopolysaccharides |
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