AR002009A1 - Composicion farmaceutica, procedimiento para la manufactura de un polvo de proliposoma como el utilizado en dicha composicion, procedimiento para lamanufactura de dicha composicion, uso de dicha composicion farmaceutica en la manufactura de un medicamento y dispositivo inhalador de polvo seco. - Google Patents
Composicion farmaceutica, procedimiento para la manufactura de un polvo de proliposoma como el utilizado en dicha composicion, procedimiento para lamanufactura de dicha composicion, uso de dicha composicion farmaceutica en la manufactura de un medicamento y dispositivo inhalador de polvo seco.Info
- Publication number
- AR002009A1 AR002009A1 ARP950100614A AR10061495A AR002009A1 AR 002009 A1 AR002009 A1 AR 002009A1 AR P950100614 A ARP950100614 A AR P950100614A AR 10061495 A AR10061495 A AR 10061495A AR 002009 A1 AR002009 A1 AR 002009A1
- Authority
- AR
- Argentina
- Prior art keywords
- manufacture
- composition
- pharmaceutical composition
- procedure
- powder
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000000843 powder Substances 0.000 abstract 4
- 150000002632 lipids Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una composición farmacéutica que comprende un polvo de proliposoma, comprendiendo dicho polvo, en una única fase, partículas discretas de uncomponente biológicamente activo junto con un lípido o mezcla de lípidos que tiene una temperaturade transición de fase por debajo de 37°C y un portadorcristalino e hidrofílico farmacéuticamente aceptable. Además, se dan a conocer un procedimiento para la manufactura de un polvo de proliposoma como elutilizado en dicha composición farmacéutica,un procedimiento para la manufactura de dicha composición farmacéutica, el uso de dicha composiciónfarmacéutica en la manufactura de un medicamento y un dispositivo inhalador de polvo seco.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9404466A SE9404466D0 (sv) | 1994-12-22 | 1994-12-22 | Process for the preparation of powders for inhalation |
| SE9502369A SE9502369D0 (sv) | 1995-06-30 | 1995-06-30 | Process for the preparation of compositions for inhalation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR002009A1 true AR002009A1 (es) | 1998-01-07 |
Family
ID=26662194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP950100614A AR002009A1 (es) | 1994-12-22 | 1995-12-18 | Composicion farmaceutica, procedimiento para la manufactura de un polvo de proliposoma como el utilizado en dicha composicion, procedimiento para lamanufactura de dicha composicion, uso de dicha composicion farmaceutica en la manufactura de un medicamento y dispositivo inhalador de polvo seco. |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6045828A (es) |
| EP (1) | EP0800383B1 (es) |
| JP (1) | JPH10510830A (es) |
| KR (1) | KR100432461B1 (es) |
| CN (1) | CN1087932C (es) |
| AR (1) | AR002009A1 (es) |
| AT (1) | ATE240095T1 (es) |
| AU (1) | AU693632B2 (es) |
| BR (1) | BR9510512A (es) |
| CA (1) | CA2208517A1 (es) |
| CZ (1) | CZ286469B6 (es) |
| DE (1) | DE69530792T2 (es) |
| DK (1) | DK0800383T3 (es) |
| EE (1) | EE03592B1 (es) |
| EG (1) | EG23683A (es) |
| ES (1) | ES2194931T3 (es) |
| FI (1) | FI972653L (es) |
| HU (1) | HUT77628A (es) |
| IL (1) | IL116454A (es) |
| IS (1) | IS1978B (es) |
| MY (1) | MY114114A (es) |
| NO (1) | NO320434B1 (es) |
| NZ (1) | NZ298180A (es) |
| PL (1) | PL184393B1 (es) |
| PT (1) | PT800383E (es) |
| RU (1) | RU2162689C2 (es) |
| SA (1) | SA95160463B1 (es) |
| SK (1) | SK284918B6 (es) |
| TR (1) | TR199501633A1 (es) |
| TW (1) | TW508248B (es) |
| UA (1) | UA43886C2 (es) |
| WO (1) | WO1996019199A1 (es) |
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| US7348025B2 (en) | 1997-09-23 | 2008-03-25 | Research Development Foundation | Small particle liposome aerosols for delivery of anticancer drugs |
| US6090407A (en) | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
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| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| WO2017194454A1 (en) * | 2016-05-09 | 2017-11-16 | Astrazeneca Ab | Lipid nanoparticles comprising lipophilic anti-inflammatory agents and methods of use thereof |
| CN111278441A (zh) * | 2017-10-11 | 2020-06-12 | 巴斯特生物技术 | 用于治疗纤维化的组合物和方法 |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| EP3787602A4 (en) | 2018-05-02 | 2022-03-23 | Insmed Incorporated | PROCESS FOR THE MANUFACTURE OF LIPOSOMAL DRUG FORMULATIONS |
| AU2023288123A1 (en) * | 2022-06-21 | 2025-01-16 | Hovione Scientia Limited | Crystalline pharmaceutical composition for inhalation comprising sugar and lipid composite particles and process for manufacture |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US514674A (en) * | 1894-02-13 | Ejector for breakdown guns | ||
| EP0026241B1 (en) * | 1978-10-12 | 1984-03-14 | Bowater-Scott Limited | Holder and dispenser for stacked rolls |
| GB2135647A (en) * | 1983-02-15 | 1984-09-05 | Squibb & Sons Inc | Method of preparing liposomes and products produced thereby |
| US4744989A (en) * | 1984-02-08 | 1988-05-17 | E. R. Squibb & Sons, Inc. | Method of preparing liposomes and products produced thereby |
| JPH0753661B2 (ja) * | 1984-03-08 | 1995-06-07 | フアレス フアーマスーチカル リサーチ エヌブイ | プロ―リポソーム組成物及びリポソームの水性分散物を作る方法 |
| SE8601457D0 (sv) * | 1986-04-01 | 1986-04-01 | Draco Ab | Compositions of liposomes and b?712-receptor active substances for inhalation |
| SE8603812D0 (sv) * | 1986-09-12 | 1986-09-12 | Draco Ab | Administration of liposomes to mammals |
| US5096629A (en) * | 1988-08-29 | 1992-03-17 | 501 Nippon Fine Chemical Co., Ltd. | Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes |
| RU2014071C1 (ru) * | 1991-03-26 | 1994-06-15 | Научно-производственный центр медицинской биотехнологии | Способ получения липосом, содержащих водорастворимые низкомолекулярные соединения |
| CA2087902C (en) * | 1992-02-05 | 2006-10-17 | Narendra Raghunathji Desai | Liposome compositions of porphyrin photosensitizers |
| JPH09501168A (ja) * | 1993-08-06 | 1997-02-04 | オパーバス ホールディング ビー ヴィ | 生物構造体、生体ポリマー及び／又はオリゴマーを充填した小胞の調製方法 |
| US5635206A (en) * | 1994-01-20 | 1997-06-03 | Hoffmann-La Roche Inc. | Process for liposomes or proliposomes |
| SA95160463B1 (ar) * | 1994-12-22 | 2005-10-04 | استرا أكتيبولاج | مساحيق للاستنشاق |
-
1995
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- 1995-12-18 AR ARP950100614A patent/AR002009A1/es unknown
- 1995-12-19 IL IL11645495A patent/IL116454A/en not_active IP Right Cessation
- 1995-12-19 TW TW084113555A patent/TW508248B/zh not_active IP Right Cessation
- 1995-12-20 EP EP95942357A patent/EP0800383B1/en not_active Expired - Lifetime
- 1995-12-20 SK SK814-97A patent/SK284918B6/sk unknown
- 1995-12-20 NZ NZ298180A patent/NZ298180A/xx unknown
- 1995-12-20 RU RU97112399/14A patent/RU2162689C2/ru not_active IP Right Cessation
- 1995-12-20 CA CA002208517A patent/CA2208517A1/en not_active Abandoned
- 1995-12-20 WO PCT/SE1995/001560 patent/WO1996019199A1/en not_active Ceased
- 1995-12-20 PL PL95320825A patent/PL184393B1/pl not_active IP Right Cessation
- 1995-12-20 BR BR9510512A patent/BR9510512A/pt not_active IP Right Cessation
- 1995-12-20 ES ES95942357T patent/ES2194931T3/es not_active Expired - Lifetime
- 1995-12-20 CZ CZ19971948A patent/CZ286469B6/cs not_active IP Right Cessation
- 1995-12-20 KR KR1019970704253A patent/KR100432461B1/ko not_active Expired - Fee Related
- 1995-12-20 US US08/617,918 patent/US6045828A/en not_active Expired - Lifetime
- 1995-12-20 JP JP8519738A patent/JPH10510830A/ja not_active Ceased
- 1995-12-20 DK DK95942357T patent/DK0800383T3/da active
- 1995-12-20 HU HU9800352A patent/HUT77628A/hu unknown
- 1995-12-20 UA UA97073873A patent/UA43886C2/uk unknown
- 1995-12-20 AU AU43605/96A patent/AU693632B2/en not_active Ceased
- 1995-12-20 DE DE69530792T patent/DE69530792T2/de not_active Expired - Lifetime
- 1995-12-20 PT PT95942357T patent/PT800383E/pt unknown
- 1995-12-20 EE EE9700134A patent/EE03592B1/xx not_active IP Right Cessation
- 1995-12-20 MY MYPI95003994A patent/MY114114A/en unknown
- 1995-12-20 AT AT95942357T patent/ATE240095T1/de not_active IP Right Cessation
- 1995-12-20 CN CN95196978A patent/CN1087932C/zh not_active Expired - Fee Related
- 1995-12-20 FI FI972653A patent/FI972653L/fi not_active Application Discontinuation
- 1995-12-21 EG EG106095A patent/EG23683A/xx active
- 1995-12-21 TR TR95/01633A patent/TR199501633A1/xx unknown
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1997
- 1997-06-06 IS IS4500A patent/IS1978B/is unknown
- 1997-06-19 NO NO19972847A patent/NO320434B1/no unknown
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