AR018252A1 - Forma de dosificacion farmaceutica en particulas solidas adecuada para suministro oral. - Google Patents
Forma de dosificacion farmaceutica en particulas solidas adecuada para suministro oral.Info
- Publication number
- AR018252A1 AR018252A1 ARP980104098A ARP980104098A AR018252A1 AR 018252 A1 AR018252 A1 AR 018252A1 AR P980104098 A ARP980104098 A AR P980104098A AR P980104098 A ARP980104098 A AR P980104098A AR 018252 A1 AR018252 A1 AR 018252A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- solid particles
- pharmaceutical dosage
- particles suitable
- oral supply
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Dispersiones de partículas solidas de agentes farmacéuticos en una matriz de un polímero soluble en agua que exhiben buena disolucion acuosay aumento de biodisponibilidad.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5619597P | 1997-08-21 | 1997-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018252A1 true AR018252A1 (es) | 2001-11-14 |
Family
ID=22002810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104098A AR018252A1 (es) | 1997-08-21 | 1998-08-19 | Forma de dosificacion farmaceutica en particulas solidas adecuada para suministro oral. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20010048946A1 (es) |
| EP (1) | EP1011640A1 (es) |
| JP (1) | JP2001515029A (es) |
| KR (1) | KR20010023085A (es) |
| AR (1) | AR018252A1 (es) |
| AU (1) | AU8600098A (es) |
| BR (1) | BR9811972A (es) |
| CA (1) | CA2292586C (es) |
| CO (1) | CO4960652A1 (es) |
| GT (1) | GT199800136A (es) |
| HN (1) | HN1998000115A (es) |
| NZ (1) | NZ502869A (es) |
| PA (1) | PA8458101A1 (es) |
| PE (1) | PE109599A1 (es) |
| SV (1) | SV1998000104A (es) |
| WO (1) | WO1999008660A1 (es) |
| ZA (1) | ZA987551B (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1537292A (en) * | 1991-04-16 | 1992-11-17 | Nippon Shinyaku Co. Ltd. | Method of manufacturing solid dispersion |
| KR100226553B1 (ko) * | 1991-08-02 | 1999-10-15 | 윌컴 터프팅 피티와이. 리미티드 | 터프트 방법 및 장치 |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| US20030153607A1 (en) * | 1998-11-12 | 2003-08-14 | Smithkline Beecham P.L.C. | Novel composition and use |
| US20040102486A1 (en) * | 1998-11-12 | 2004-05-27 | Smithkline Beecham Corporation | Novel method of treatment |
| DZ3227A1 (fr) | 1999-12-23 | 2001-07-05 | Pfizer Prod Inc | Compositions pharmaceutiques fournissant des concentrations de medicaments ameliorees |
| DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| DE60143704D1 (de) * | 2000-09-25 | 2011-02-03 | Nippon Shinyaku Co Ltd | Verfahren zur herstellung einer medizinischen festen dispersion |
| ATE293439T1 (de) * | 2000-12-07 | 2005-05-15 | Warner Lambert Co | Verfahren und system zur gleichmä igen arzneistoffabgabe |
| MXPA03011784A (es) | 2001-06-22 | 2004-04-02 | Pfizer Prod Inc | Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros. |
| GB0127805D0 (en) * | 2001-11-20 | 2002-01-09 | Smithkline Beecham Plc | Pharmaceutical composition |
| WO2003063833A1 (en) | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials |
| GB0205253D0 (en) * | 2002-03-06 | 2002-04-17 | Univ Gent | Immediate release pharmaceutical granule compositions and a continuous process for making them |
| AU2003249474A1 (en) | 2002-08-12 | 2004-02-25 | Pfizer Products Inc. | Pharmaceutical compositions of semi-ordered drugs and polymers |
| US20050220870A1 (en) * | 2003-02-20 | 2005-10-06 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
| US20050100608A1 (en) * | 2003-02-21 | 2005-05-12 | Watson Pharmaceuticals, Inc. | Testosterone oral dosage formulations and associated methods |
| US8273371B2 (en) * | 2003-06-27 | 2012-09-25 | Johan Adriaan Martens | Crystalline mesoporous oxide based materials useful for the fixation and controlled release of drugs |
| GB0315012D0 (en) * | 2003-06-27 | 2003-07-30 | Leuven K U Res & Dev | Zeotiles |
| JP2006528181A (ja) * | 2003-07-18 | 2006-12-14 | サンタラス インコーポレイティッド | 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法 |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| MXPA06001417A (es) | 2003-08-04 | 2006-05-15 | Pfizer Prod Inc | Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas. |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| JP2007513145A (ja) * | 2003-12-04 | 2007-05-24 | ファイザー・プロダクツ・インク | 医薬用多微粒子の製造方法 |
| JP2007522217A (ja) * | 2004-02-10 | 2007-08-09 | サンタラス インコーポレイティッド | プロトンポンプ阻害剤、緩衝剤および非ステロイド系抗炎症薬の組み合わせ |
| US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
| US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| CA2598204C (en) | 2004-11-09 | 2015-01-13 | Board Of Regents, The University Of Texas System | Stabilized hme composition with small drug particles |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| FR2880274B1 (fr) * | 2004-12-30 | 2007-04-13 | Pierre Fabre Medicament Sa | Dispersion solide stable d'un derive d'alcaloides de vinca et son procede de fabrication |
| US20060147518A1 (en) * | 2004-12-30 | 2006-07-06 | Pierre Fabre Medicament | Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it |
| US9061015B2 (en) * | 2004-12-30 | 2015-06-23 | Pierre Fabre Medicament | Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it |
| BRPI0608609A2 (pt) * | 2005-05-10 | 2010-01-19 | Novartis Ag | processo de extrusço para preparaÇço de composiÇÕes com compostos terapÊuticos fracamente compressÍveis |
| GB0612695D0 (en) * | 2006-06-27 | 2006-08-09 | Univ Gent | Process for preparing a solid dosage form |
| WO2008074097A1 (en) * | 2006-12-21 | 2008-06-26 | Alphapharm Pty Ltd | Pharmaceutical compound and composition |
| MX2010014566A (es) * | 2008-07-03 | 2011-02-15 | Novartis Ag | Proceso de granulacion de fundido. |
| WO2010136604A1 (en) * | 2009-05-29 | 2010-12-02 | Dsm Ip Assets B.V. | Transfer matrix for transferring a bioactive agent to body tissue |
| EP2675434A1 (en) | 2011-02-17 | 2013-12-25 | F.Hoffmann-La Roche Ag | A process for controlled crystallization of an active pharmaceutical ingredient from supercooled liquid state by hot melt extrusion |
| EP2765993B1 (en) * | 2011-09-14 | 2020-05-20 | Amgen (Europe) GmbH | Formulations of cyclopropanecarboxylic acid {2-[(1s)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2, 3-dihydro-1h-isoindol-4-yl}-amide |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンa物質含有易溶性固形製剤 |
| JPH054919A (ja) * | 1990-07-25 | 1993-01-14 | Sankyo Co Ltd | チアゾリジン誘導体の固体分散体 |
| AU1537292A (en) * | 1991-04-16 | 1992-11-17 | Nippon Shinyaku Co. Ltd. | Method of manufacturing solid dispersion |
| DK0617612T3 (da) * | 1991-12-18 | 1998-04-14 | Warner Lambert Co | Fremgangsmåde til fremstilling af en fast dispersion |
| US5340591A (en) * | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| DE4226753A1 (de) * | 1992-08-13 | 1994-02-17 | Basf Ag | Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen |
| JPH07324086A (ja) * | 1994-05-31 | 1995-12-12 | Sankyo Co Ltd | チアゾリジン誘導体の固体分散体または固体分散体製剤 |
| DE19515972A1 (de) * | 1995-05-02 | 1996-11-07 | Bayer Ag | Arzneizubereitungen mit kontrollierter Freisetzung und Verfahren zu ihrer Herstellung |
-
1998
- 1998-07-24 HN HN1998000115A patent/HN1998000115A/es unknown
- 1998-07-29 KR KR1020007001704A patent/KR20010023085A/ko not_active Ceased
- 1998-07-29 CA CA002292586A patent/CA2292586C/en not_active Expired - Fee Related
- 1998-07-29 AU AU86000/98A patent/AU8600098A/en not_active Abandoned
- 1998-07-29 BR BR9811972-9A patent/BR9811972A/pt not_active Application Discontinuation
- 1998-07-29 WO PCT/US1998/015693 patent/WO1999008660A1/en not_active Ceased
- 1998-07-29 NZ NZ502869A patent/NZ502869A/xx unknown
- 1998-07-29 JP JP2000509400A patent/JP2001515029A/ja not_active Abandoned
- 1998-07-29 US US09/284,858 patent/US20010048946A1/en not_active Abandoned
- 1998-07-29 EP EP98937241A patent/EP1011640A1/en not_active Withdrawn
- 1998-08-19 AR ARP980104098A patent/AR018252A1/es unknown
- 1998-08-20 CO CO98047585A patent/CO4960652A1/es unknown
- 1998-08-20 ZA ZA987551A patent/ZA987551B/xx unknown
- 1998-08-20 GT GT199800136A patent/GT199800136A/es unknown
- 1998-08-20 PA PA19988458101A patent/PA8458101A1/es unknown
- 1998-08-20 SV SV1998000104A patent/SV1998000104A/es not_active Application Discontinuation
- 1998-08-20 PE PE1998000752A patent/PE109599A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2292586A1 (en) | 1999-02-25 |
| GT199800136A (es) | 2000-02-11 |
| HN1998000115A (es) | 1999-06-02 |
| PA8458101A1 (es) | 2001-12-14 |
| WO1999008660A1 (en) | 1999-02-25 |
| ZA987551B (en) | 1999-02-23 |
| SV1998000104A (es) | 1999-07-02 |
| EP1011640A1 (en) | 2000-06-28 |
| CO4960652A1 (es) | 2000-09-25 |
| AU8600098A (en) | 1999-03-08 |
| PE109599A1 (es) | 1999-12-19 |
| CA2292586C (en) | 2006-02-14 |
| JP2001515029A (ja) | 2001-09-18 |
| US20010048946A1 (en) | 2001-12-06 |
| NZ502869A (en) | 2002-10-25 |
| BR9811972A (pt) | 2000-08-15 |
| KR20010023085A (ko) | 2001-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |