AR034452A2 - N-oxidos de heterociclos saturados que contienen nitrogeno y que estan sustituidos con quinoloncarboxilicos y procedimiento para su produccion. - Google Patents
N-oxidos de heterociclos saturados que contienen nitrogeno y que estan sustituidos con quinoloncarboxilicos y procedimiento para su produccion.Info
- Publication number
- AR034452A2 AR034452A2 ARP020102179A ARP020102179A AR034452A2 AR 034452 A2 AR034452 A2 AR 034452A2 AR P020102179 A ARP020102179 A AR P020102179A AR P020102179 A ARP020102179 A AR P020102179A AR 034452 A2 AR034452 A2 AR 034452A2
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- represents hydrogen
- substituted
- oxides
- production
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 title abstract 2
- 229920006395 saturated elastomer Polymers 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- -1 methoxy, cyclopropyl Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 1
- 125000001539 acetonyl group Chemical group [H]C([H])([H])C(=O)C([H])([H])* 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Abstract
N-óxidos de heterociclos saturados que contienen nitrógeno y que están sustituidos con ácidos quinoloncarboxílicos, que tienen la fórmula (1), en la cual Y representa restos de estructuras (2), (3), (4) y (5); donde R4 representa alquilo C1-4 lineal o ramificado, opcionalmente sustituido con hidroxilo o metoxi, ciclopropilo, acilo C1-3; R5 representa hidrógeno, metilo, fenilo, tienilo o piridilo; R6 representa hidrógeno o alquilo C1-4; R7 representa hidrógeno o alquilo C1-4; R8 representa hidrógeno o alquilo C1-4 y R2 representa hidrógeno o alquilo C1-4, opcionalmente sustituido con metoxi y bencilo, 2-oxopropilo, fenacilo y etoxicarbonilmetilo; A representa =N, =CH-, =C(halógeno)- o =C(OCH3)-, así como sus hidratos o sales de adición de ácido o sales con bases utilizables farmacéuticamente y procedimiento para su producción
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19519822A DE19519822A1 (de) | 1995-05-31 | 1995-05-31 | Neue antibakterielle Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR034452A2 true AR034452A2 (es) | 2004-02-25 |
Family
ID=7763230
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960102727A AR003420A1 (es) | 1995-05-31 | 1996-05-24 | Composiciones antibacterianas a base de n-oxidos de heterociclos saturados que contienen nitrogeno, y uso de los mismos para la produccion de composiciones |
| ARP020102179A AR034452A2 (es) | 1995-05-31 | 2002-06-10 | N-oxidos de heterociclos saturados que contienen nitrogeno y que estan sustituidos con quinoloncarboxilicos y procedimiento para su produccion. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960102727A AR003420A1 (es) | 1995-05-31 | 1996-05-24 | Composiciones antibacterianas a base de n-oxidos de heterociclos saturados que contienen nitrogeno, y uso de los mismos para la produccion de composiciones |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6114351A (es) |
| EP (1) | EP0828715B1 (es) |
| JP (1) | JP3868492B2 (es) |
| KR (1) | KR100682746B1 (es) |
| CN (1) | CN1214009C (es) |
| AR (2) | AR003420A1 (es) |
| AT (1) | ATE204256T1 (es) |
| AU (1) | AU707628B2 (es) |
| BR (1) | BR9608593A (es) |
| CA (1) | CA2222552C (es) |
| CZ (1) | CZ290675B6 (es) |
| DE (2) | DE19519822A1 (es) |
| DK (1) | DK0828715T3 (es) |
| ES (1) | ES2161361T3 (es) |
| GR (1) | GR3037063T3 (es) |
| HU (1) | HUP9802076A3 (es) |
| NO (1) | NO319510B1 (es) |
| NZ (1) | NZ309074A (es) |
| PL (1) | PL187322B1 (es) |
| SK (1) | SK283994B6 (es) |
| TW (1) | TW442290B (es) |
| WO (1) | WO1996038417A1 (es) |
| ZA (1) | ZA964414B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904108D0 (sv) * | 1999-11-15 | 1999-11-15 | New Pharma Research Ab | Nya föreningar |
| US9625065B2 (en) | 2004-09-03 | 2017-04-18 | Loewenstein Medical Technology S.A. | Plastics for medical technical devices |
| FR2896416B1 (fr) * | 2006-01-24 | 2010-08-13 | Vetoquinol | Composition anti-infectieuse comprenant un compose de type pyrido (3,2,1-ij)-benzoxadiazine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3363711D1 (en) * | 1982-03-31 | 1986-07-03 | Sterling Drug Inc | New quinolone compounds and preparation thereof |
| US5152984A (en) * | 1990-11-20 | 1992-10-06 | Dow Corning Corporation | Hair fixatives |
-
1995
- 1995-05-31 DE DE19519822A patent/DE19519822A1/de not_active Withdrawn
-
1996
- 1996-04-30 TW TW085105109A patent/TW442290B/zh not_active IP Right Cessation
- 1996-05-20 ES ES96916138T patent/ES2161361T3/es not_active Expired - Lifetime
- 1996-05-20 DK DK96916138T patent/DK0828715T3/da active
- 1996-05-20 BR BR9608593A patent/BR9608593A/pt not_active Application Discontinuation
- 1996-05-20 SK SK1603-97A patent/SK283994B6/sk not_active IP Right Cessation
- 1996-05-20 NZ NZ309074A patent/NZ309074A/xx not_active IP Right Cessation
- 1996-05-20 EP EP96916138A patent/EP0828715B1/de not_active Expired - Lifetime
- 1996-05-20 CN CNB961956151A patent/CN1214009C/zh not_active Expired - Fee Related
- 1996-05-20 CA CA002222552A patent/CA2222552C/en not_active Expired - Fee Related
- 1996-05-20 US US08/952,762 patent/US6114351A/en not_active Expired - Lifetime
- 1996-05-20 CZ CZ19973748A patent/CZ290675B6/cs not_active IP Right Cessation
- 1996-05-20 AT AT96916138T patent/ATE204256T1/de not_active IP Right Cessation
- 1996-05-20 AU AU59005/96A patent/AU707628B2/en not_active Ceased
- 1996-05-20 JP JP53614796A patent/JP3868492B2/ja not_active Expired - Fee Related
- 1996-05-20 DE DE59607503T patent/DE59607503D1/de not_active Expired - Lifetime
- 1996-05-20 KR KR1019970708523A patent/KR100682746B1/ko not_active Expired - Fee Related
- 1996-05-20 PL PL96323622A patent/PL187322B1/pl not_active IP Right Cessation
- 1996-05-20 HU HU9802076A patent/HUP9802076A3/hu unknown
- 1996-05-20 WO PCT/EP1996/002171 patent/WO1996038417A1/de not_active Ceased
- 1996-05-24 AR ARP960102727A patent/AR003420A1/es unknown
- 1996-05-30 ZA ZA964414A patent/ZA964414B/xx unknown
-
1997
- 1997-11-27 NO NO19975464A patent/NO319510B1/no not_active IP Right Cessation
-
2001
- 2001-10-30 GR GR20010401935T patent/GR3037063T3/el unknown
-
2002
- 2002-06-10 AR ARP020102179A patent/AR034452A2/es active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |