AR045290A1 - Acido graso desaturasas de primula - Google Patents

Acido graso desaturasas de primula

Info

Publication number
AR045290A1
AR045290A1 ARP040102992A ARP040102992A AR045290A1 AR 045290 A1 AR045290 A1 AR 045290A1 AR P040102992 A ARP040102992 A AR P040102992A AR P040102992 A ARP040102992 A AR P040102992A AR 045290 A1 AR045290 A1 AR 045290A1
Authority
AR
Argentina
Prior art keywords
seq
polynucleotide
desaturase
polypeptide
sequence
Prior art date
Application number
ARP040102992A
Other languages
English (en)
Inventor
Virginia Ursin
Byron Froman
Jennifer Gonzales
Steven Screen
Fenggao Dong
Rosa Thomas La
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34272508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR045290(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of AR045290A1 publication Critical patent/AR045290A1/es

Links

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Métodos y composiciones que se refieren a enzimas desaturasa que modulan la cantidad y ubicación de enlaces dobles en ácidos grasos poli-insaturados de cadena larga (LC-PUFA). En particular, se relaciona con métodos y composiciones para mejorar los perfiles de ácidos grasos omega-3 en productos vegetales y partes de plantas usando enzimas desaturasa y ácidos nucleicos que codifican dichas enzimas. En realizaciones particulares, las enzimas desaturasa son desaturasa de Primula. También se proveen composiciones mejoradas de aceite de soja que contienen SDA y un contenido beneficioso general de ácidos grasos omega-3 con relación a ácidos grasos omega-6. Reivindicación 1: Un polinucleótido aislado que codifica un polipéptido con actividad desaturasa que desatura una molécula de ácido graso en el carbono 6, donde dicho polinucleótido se selecciona del grupo formado por: a) un polinucleótido que codifica la secuencia de polipéptidos de las SEQ ID N°: 4, SEQ ID N°: 5, SEQ ID N°: 22, SEQ ID N°: 24, SEQ ID N°: 26, SEQ ID N°: 46 o SEQ ID N°: 48; b) un polinucleótido que comprende la secuencia de ácido nucleico de las SEQ ID N°: 2, SEQ ID N°: 3, SEQ ID N°: 21, SEQ ID N°: 23, SEQ ID N°: 25, SEQ ID N°: 45 o SEQ ID N°: 47; c) un polinucleótido que se hibridiza con las SEQ ID N°:2, SEQ ID N°: 3, SEQ ID N°: 21, SEQ ID N°: 23, SEQ ID N°: 25, SEQ ID N°: 45 o SEQ ID N°: 47, o un complemento de las mismas, bajo condiciones de SSC 5X, formamida 50 % y 42° C; y d) un polinucleótido que codifica un polipéptido con al menos un 90 % de identidad de secuencia con la secuencia de polipéptidos de las SEQ ID N°: 4, SEQ ID N°: 5, SEQ ID N°: 22, SEQ ID N°: 24, SEQ ID N°: 26, SEQ ID N°: 46 o SEQ ID N°: 48. Reivindicación 6: Un vector recombinante que comprende la secuencia de polinucleótidos aislada de la cláusula 1. Reivindicación 12: Una planta transgénica transformada con el vector recombinante de la cláusula 6.
ARP040102992A 2003-08-21 2004-08-20 Acido graso desaturasas de primula AR045290A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49675103P 2003-08-21 2003-08-21

Publications (1)

Publication Number Publication Date
AR045290A1 true AR045290A1 (es) 2005-10-19

Family

ID=34272508

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102992A AR045290A1 (es) 2003-08-21 2004-08-20 Acido graso desaturasas de primula

Country Status (16)

Country Link
US (5) US8173870B2 (es)
EP (1) EP1656449B1 (es)
CN (1) CN1871353B (es)
AR (1) AR045290A1 (es)
AT (1) ATE430802T1 (es)
AU (1) AU2004268196B2 (es)
BR (1) BRPI0413786B1 (es)
CA (2) CA2535310C (es)
DE (1) DE602004021001D1 (es)
DK (1) DK1656449T3 (es)
ES (1) ES2323644T3 (es)
MX (1) MXPA06002028A (es)
PL (1) PL1656449T3 (es)
PT (1) PT1656449E (es)
WO (1) WO2005021761A1 (es)
ZA (1) ZA200601438B (es)

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ATE430802T1 (de) 2003-08-21 2009-05-15 Monsanto Technology Llc Fettsäuredesaturasen aus primula
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