AR045603A1 - Dispositivo de electroporacion con corriente constante y metodos de uso. - Google Patents

Dispositivo de electroporacion con corriente constante y metodos de uso.

Info

Publication number
AR045603A1
AR045603A1 ARP040103201A ARP040103201A AR045603A1 AR 045603 A1 AR045603 A1 AR 045603A1 AR P040103201 A ARP040103201 A AR P040103201A AR P040103201 A ARP040103201 A AR P040103201A AR 045603 A1 AR045603 A1 AR 045603A1
Authority
AR
Argentina
Prior art keywords
electroporation device
needle
ekd
electrodes
methods
Prior art date
Application number
ARP040103201A
Other languages
English (en)
Inventor
Louis C Smith
Ruxandra Draghia-Akli
Amir Khan
Robert H Carpenter
Jeff Darnell
Original Assignee
Advisys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advisys Inc filed Critical Advisys Inc
Publication of AR045603A1 publication Critical patent/AR045603A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrotherapy Devices (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Un dispositivo de electroporación que puede ser usado para facilitar efectivamente la introducción de una macromolécula dentro de las células de un tejido seleccionado de un cuerpo o planta. El dispositivo de electroporación comprende un dispositivo electro-cinético("EKD") cuya operación se especifica mediante un software o firmware. El EKD produce una serie de patrones de pulso de corriente-constante programable entre los electrodos, en un arreglo basado en el control del usuario y el ingreso de los parámetros de pulso, y en permitir el almacenamiento y la adquisición de los datos de la onda de corriente. El dispositivo de electroporación también comprende un disco de electrodos reemplazable que tiene un arreglo de electrodos de agujas, un canal de inyección central para una aguja, un canal de inyección central para una aguja de inyección y un disco guía removible.
ARP040103201A 2003-09-08 2004-09-07 Dispositivo de electroporacion con corriente constante y metodos de uso. AR045603A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/657,725 US8209006B2 (en) 2002-03-07 2003-09-08 Constant current electroporation device and methods of use

Publications (1)

Publication Number Publication Date
AR045603A1 true AR045603A1 (es) 2005-11-02

Family

ID=34312678

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040103201A AR045603A1 (es) 2003-09-08 2004-09-07 Dispositivo de electroporacion con corriente constante y metodos de uso.

Country Status (9)

Country Link
US (1) US8209006B2 (es)
EP (1) EP1673140B1 (es)
AR (1) AR045603A1 (es)
CA (1) CA2578847C (es)
ES (1) ES2668384T3 (es)
HU (1) HUE038018T2 (es)
PL (1) PL1673140T3 (es)
TW (1) TWI246930B (es)
WO (1) WO2005025669A2 (es)

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CA2578847C (en) 2014-01-28
CA2578847A1 (en) 2005-03-24

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