AR062940A1 - Compuestos para el tratamiento de desordenes metabolicos - Google Patents

Compuestos para el tratamiento de desordenes metabolicos

Info

Publication number: AR062940A1
Authority: AR; Argentina
Prior art keywords: compounds; hydrogen; alkyl; treatment; metabolic disorders
Prior art date: 2006-09-21

Application number

ARP070104183A

Other languages

English (en)

Spanish (es)

Inventor

Sivaramkrishnan Hariharan

Nabajyoti Deka

Swapnil Ramesh Bajare

Rosalid Adalkalasamy Marita

Original Assignee

Nicholas Piramal India Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-21

Filing date

2007-09-21

Publication date

2008-12-17

2007-09-21 Application filed by Nicholas Piramal India Ltd filed Critical Nicholas Piramal India Ltd

2008-12-17 Publication of AR062940A1 publication Critical patent/AR062940A1/es

Links

150000001875 compounds Chemical class 0.000 title abstract 4
208000030159 metabolic disease Diseases 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
201000001421 hyperglycemia Diseases 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

ARP070104183A 2006-09-21 2007-09-21 Compuestos para el tratamiento de desordenes metabolicos AR062940A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US84619406P	2006-09-21	2006-09-21
US87567206P	2006-12-18	2006-12-18

Publications (1)

Publication Number	Publication Date
AR062940A1 true AR062940A1 (es)	2008-12-17

Family

ID=39048032

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ARP070104183A AR062940A1 (es)	2006-09-21	2007-09-21	Compuestos para el tratamiento de desordenes metabolicos
ARP070104184A AR062941A1 (es)	2006-09-21	2007-09-21	Compuestos para el tratamiento de desordenes metabolicos

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ARP070104184A AR062941A1 (es)	2006-09-21	2007-09-21	Compuestos para el tratamiento de desordenes metabolicos

Country Status (19)

Country	Link
US (5)	US8269010B2 (pt)
EP (2)	EP2094687A1 (pt)
JP (2)	JP5331953B2 (pt)
KR (2)	KR20090075827A (pt)
AR (2)	AR062940A1 (pt)
AT (1)	ATE496890T1 (pt)
AU (2)	AU2007298540B2 (pt)
BR (2)	BRPI0717106A2 (pt)
CA (2)	CA2663943A1 (pt)
DE (1)	DE602007012299D1 (pt)
DK (1)	DK2094663T3 (pt)
IL (2)	IL197695A0 (pt)
MX (2)	MX2009002905A (pt)
NZ (2)	NZ576196A (pt)
PL (1)	PL2094663T3 (pt)
PT (1)	PT2094663E (pt)
RU (2)	RU2460729C2 (pt)
TW (2)	TW200817364A (pt)
WO (2)	WO2008035306A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013117963A1 (en)	2012-02-09	2013-08-15	Piramal Enterprises Limited	Stable oral tablet dosage form of an antidiabetic compound
WO2014207508A1 (en) *	2013-06-27	2014-12-31	Piramal Enterprises Limited	Pyridyl compound suitable for the treatment of metabolic disorders
DK3013813T3 (da)	2013-06-27	2019-06-03	Pfizer	Heteroaromatiske forbindelser og anvendelse deraf som dopamin-d1-ligander
EA028614B1 (ru) *	2014-05-22	2017-12-29	Общество С Ограниченной Ответственностью "Русские Фармацевтические Технологии"	Селективные ингибиторы, нарушающие взаимодействие рецептора фактора роста фибробластов и frs2, для профилактики и лечения рака
EP2974729A1 (en)	2014-07-17	2016-01-20	Abivax	Quinoline derivatives for use in the treatment of inflammatory diseases
EP3669873A1 (en)	2018-12-20	2020-06-24	Abivax	Quinoline derivatives for use ine the traeatment of inflammation diseases
AU2021376300A1 (en)	2020-11-09	2023-06-22	Eisai R&D Management Co., Ltd.	ΡΡΑRγ MODULATORS AND METHODS OF USE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5084085A (en) *	1986-08-20	1992-01-28	Fmc Corporation	Herbicidal aryloxyphenyltriazolinones and related compounds
UA58494C2 (uk) *	1995-06-07	2003-08-15	Зенека Лімітед	Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
US6583157B2 (en) *	1998-01-29	2003-06-24	Tularik Inc.	Quinolinyl and benzothiazolyl modulators
PL351470A1 (en)	1999-04-28	2003-04-22	Aventis Pharma Gmbh	Tri-aryl acid derivatives as ppar receptor ligands
US7041691B1 (en) *	1999-06-30	2006-05-09	Amgen Inc.	Compounds for the modulation of PPARγ activity
MXPA01013199A (es) *	1999-06-30	2003-08-20	Tularik Inc	Compuestos para la modulacion de la actividad de ppary.
HK1052351B (en) *	2000-06-28	2006-11-03	Japan Tobacco Inc.	Benzothiazolyl ppar-gamma modulators
RU2337908C2 (ru) *	2003-06-12	2008-11-10	Ново Нордиск А/С	Пиридинилкарбаматы в качестве ингибиторов гормон-чувствительной липазы
US7223761B2 (en) *	2003-10-03	2007-05-29	Amgen Inc.	Salts and polymorphs of a potent antidiabetic compound
ZA200700811B (en) *	2004-08-06	2008-10-29	Otsuka Pharma Co Ltd	Aromatic compound
EP1799647A1 (en)	2004-10-04	2007-06-27	F.Hoffmann-La Roche Ag	Alkil-pyridines as 11-beta inhibitors for diabetes

2007
- 2007-09-20 BR BRPI0717106-4A patent/BRPI0717106A2/pt not_active IP Right Cessation
- 2007-09-20 AU AU2007298540A patent/AU2007298540B2/en not_active Ceased
- 2007-09-20 TW TW096135227A patent/TW200817364A/zh unknown
- 2007-09-20 US US12/441,891 patent/US8269010B2/en not_active Expired - Fee Related
- 2007-09-20 MX MX2009002905A patent/MX2009002905A/es active IP Right Grant
- 2007-09-20 AU AU2007298539A patent/AU2007298539B2/en not_active Ceased
- 2007-09-20 CA CA002663943A patent/CA2663943A1/en not_active Abandoned
- 2007-09-20 JP JP2009528851A patent/JP5331953B2/ja not_active Expired - Fee Related
- 2007-09-20 DE DE602007012299T patent/DE602007012299D1/de active Active
- 2007-09-20 NZ NZ576196A patent/NZ576196A/en not_active IP Right Cessation
- 2007-09-20 AT AT07826467T patent/ATE496890T1/de active
- 2007-09-20 RU RU2009114545/04A patent/RU2460729C2/ru not_active IP Right Cessation
- 2007-09-20 KR KR1020097008115A patent/KR20090075827A/ko not_active Ceased
- 2007-09-20 CA CA002663901A patent/CA2663901A1/en not_active Abandoned
- 2007-09-20 DK DK07826467.8T patent/DK2094663T3/da active
- 2007-09-20 WO PCT/IB2007/053812 patent/WO2008035306A1/en not_active Ceased
- 2007-09-20 EP EP07826468A patent/EP2094687A1/en not_active Withdrawn
- 2007-09-20 MX MX2009002906A patent/MX2009002906A/es active IP Right Grant
- 2007-09-20 NZ NZ576197A patent/NZ576197A/en not_active IP Right Cessation
- 2007-09-20 BR BRPI0718510-3A patent/BRPI0718510A2/pt not_active IP Right Cessation
- 2007-09-20 RU RU2009114544/04A patent/RU2448093C2/ru not_active IP Right Cessation
- 2007-09-20 PL PL07826467T patent/PL2094663T3/pl unknown
- 2007-09-20 JP JP2009528850A patent/JP2010504321A/ja not_active Ceased
- 2007-09-20 TW TW096135229A patent/TW200820970A/zh unknown
- 2007-09-20 WO PCT/IB2007/053811 patent/WO2008035305A2/en not_active Ceased
- 2007-09-20 EP EP07826467A patent/EP2094663B1/en not_active Not-in-force
- 2007-09-20 US US12/441,802 patent/US8030324B2/en not_active Expired - Fee Related
- 2007-09-20 KR KR1020097008116A patent/KR20090074775A/ko not_active Ceased
- 2007-09-20 PT PT07826467T patent/PT2094663E/pt unknown
- 2007-09-21 AR ARP070104183A patent/AR062940A1/es unknown
- 2007-09-21 AR ARP070104184A patent/AR062941A1/es not_active Application Discontinuation
2009
- 2009-03-19 IL IL197695A patent/IL197695A0/en unknown
- 2009-03-19 IL IL197694A patent/IL197694A0/en unknown
2011
- 2011-08-31 US US13/222,662 patent/US8349862B2/en not_active Expired - Fee Related
2012
- 2012-08-13 US US13/584,043 patent/US20130040988A1/en not_active Abandoned
- 2012-08-13 US US13/584,134 patent/US20120309786A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR20090075827A (ko)	2009-07-09
US8349862B2 (en)	2013-01-08
TW200820970A (en)	2008-05-16
EP2094663A2 (en)	2009-09-02
AR062941A1 (es)	2008-12-17
JP2010504322A (ja)	2010-02-12
BRPI0717106A2 (pt)	2013-10-08
US8030324B2 (en)	2011-10-04
IL197694A0 (en)	2009-12-24
PT2094663E (pt)	2011-04-19
CA2663943A1 (en)	2008-03-27
WO2008035306A1 (en)	2008-03-27
RU2009114545A (ru)	2010-10-27
US20110312970A1 (en)	2011-12-22
US20090247574A1 (en)	2009-10-01
EP2094663B1 (en)	2011-01-26
MX2009002905A (es)	2009-06-19
WO2008035305A8 (en)	2009-03-12
EP2094687A1 (en)	2009-09-02
US8269010B2 (en)	2012-09-18
RU2460729C2 (ru)	2012-09-10
AU2007298539A1 (en)	2008-03-27
RU2448093C2 (ru)	2012-04-20
WO2008035305A3 (en)	2008-06-12
NZ576196A (en)	2011-12-22
DE602007012299D1 (de)	2011-03-10
JP5331953B2 (ja)	2013-10-30
KR20090074775A (ko)	2009-07-07
RU2009114544A (ru)	2010-10-27
CA2663901A1 (en)	2008-03-27
DK2094663T3 (da)	2011-04-26
BRPI0718510A2 (pt)	2013-11-19
US20120309786A1 (en)	2012-12-06
JP2010504321A (ja)	2010-02-12
MX2009002906A (es)	2009-06-30
US20100022554A1 (en)	2010-01-28
PL2094663T3 (pl)	2011-07-29
AU2007298540A1 (en)	2008-03-27
AU2007298539B2 (en)	2013-05-02
ATE496890T1 (de)	2011-02-15
NZ576197A (en)	2011-12-22
WO2008035305A2 (en)	2008-03-27
TW200817364A (en)	2008-04-16
AU2007298540B2 (en)	2013-02-21
IL197695A0 (en)	2009-12-24
US20130040988A1 (en)	2013-02-14

Legal Events

Date	Code	Title	Description
2010-10-05	FB	Suspension of granting procedure

Publication	Publication Date	Title
AR062940A1 (es)	2008-12-17	Compuestos para el tratamiento de desordenes metabolicos
EA200970585A1 (ru)	2009-10-30	Бензамидные производные как агонисты ер-рецепторов
CA2646962A1 (en)	2007-11-08	Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
CA2582447A1 (en)	2006-04-13	Aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
TW200720266A (en)	2007-06-01	Benzodioxane and benzodioxolan derivatives and uses thereof
WO2008115098A3 (fr)	2008-11-13	2,3,4,5-tétrahydro-1h-pyrido[4,3-b]indoles substitués ainsi que procédés de leur fabrication et leur utilisation
ATE530066T1 (de)	2011-11-15	Verbindungen zur behandlung von stoffwechselstörungen
AR061374A1 (es)	2008-08-20	Derivados de diamidas de acido antranilico con sus sustituyentes heteroaromaticos y heterociclicos
AR072906A1 (es)	2010-09-29	Nucleosidos modificados utiles como antivirales
EA200870362A1 (ru)	2009-02-27	Способ получения производных лактамида, новые производные лактамида и препараты, содержащие производные лактамида
CR8505A (es)	2008-09-09	Derivados de (3-oxo-3,4-dihidroquinoxalin-2-il-amino)-benzamida y compuesto relacionado, como inhibidores de glucogeno fosforilasa para el tratamiento de la diabetes y obesidad
AR041298A1 (es)	2005-05-11	Derivados de pirrolidona como inhibidores de maob
TW200719886A (en)	2007-06-01	Dihydrobenzofuran derivatives and uses thereof
AR074352A1 (es)	2011-01-12	Acidos naftalen-2-il-aceticos sustituidos, composiciones farmaceuticas que los contienen, y uso de los mismos en el tratamiento de enfermedades alergicas,tales como rinitis, asma y dermatitis atopica.
TW200724136A (en)	2007-07-01	Pharmaceutical compositions comprising PPAR modulator
GB0517191D0 (en)	2005-09-28	Compounds
AR062737A1 (es)	2008-11-26	Composicion farmaceutica que comprende un compuesto derivado de aril-azabiciclo, compuesto correspondiente y su uso para la preparacion de un medicamento
AR074353A1 (es)	2011-01-12	Acidos naftalen-2-il-aceticos sustituidos, composiciones farmaceuticas que los contienen, y uso de los mismos en el tratamiento de enfermedades alergicas,tales como rinitis, asma y dermatititis atopica.
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