ATA153875A - Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saureadditionssalzen

Info

Publication number: ATA153875A
Authority: AT; Austria
Prior art keywords: benzomorphanes; tetrahydrofurfuryl; preparation; new; acid addition
Prior art date: 1974-03-09

Application number

AT153875A

Other languages

English (en)

Other versions

AT344332B (de

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-03-09

Filing date

1975-02-28

Publication date

1977-11-15

1975-02-28 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1977-11-15 Publication of ATA153875A publication Critical patent/ATA153875A/de

1978-07-10 Application granted granted Critical

1978-07-10 Publication of AT344332B publication Critical patent/AT344332B/de

Links

239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT153875A 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen AT344332B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2411382A DE2411382C3 (de)	1974-03-09	1974-03-09	2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number	Publication Date
ATA153875A true ATA153875A (de)	1977-11-15
AT344332B AT344332B (de)	1978-07-10

Family

ID=5909593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT153875A AT344332B (de)	1974-03-09	1975-02-28	Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Country Status (25)

Country	Link
JP (1)	JPS5827275B2 (de)
AT (1)	AT344332B (de)
BE (1)	BE826440A (de)
BG (3)	BG24814A4 (de)
CA (1)	CA1049511A (de)
CH (8)	CH612425A5 (de)
CS (1)	CS188221B2 (de)
DD (1)	DD119236A5 (de)
DE (1)	DE2411382C3 (de)
DK (1)	DK137188C (de)
ES (6)	ES440345A1 (de)
FI (1)	FI63571C (de)
FR (1)	FR2262984B1 (de)
GB (1)	GB1496418A (de)
HU (1)	HU177408B (de)
IE (1)	IE40945B1 (de)
IL (1)	IL46760A (de)
NL (1)	NL7502724A (de)
NO (1)	NO141800C (de)
PH (1)	PH14127A (de)
PL (3)	PL93699B1 (de)
RO (2)	RO70051A (de)
SE (1)	SE421919B (de)
SU (3)	SU577982A3 (de)
ZA (1)	ZA751394B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2716687A1 (de) *	1977-04-15	1978-10-19	Boehringer Sohn Ingelheim	2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
NZ303251A (en) *	1995-03-10	2000-10-27	Photocure Asa	Use of esters of 5-aminolevulinic acid as photosensitising agents in photochemotherapy
US6492420B2 (en)	1995-03-10	2002-12-10	Photocure As	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en)	1995-03-10	2006-01-31	Photocure Asa	Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en)	1995-03-10	2009-05-12	Photocure Asa	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en)	2000-07-27	2000-09-13	Photocure Asa	Compounds
US6723750B2 (en)	2002-03-15	2004-04-20	Allergan, Inc.	Photodynamic therapy for pre-melanomas
US8329897B2 (en)	2007-07-26	2012-12-11	Vitae Pharmaceuticals, Inc.	Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
EP2220048B1 (de)	2007-11-16	2017-01-25	Boehringer Ingelheim International GmbH	Aryl- und heteroarylcarbonylderivate von benzomorphanen und verwandten grundgerüsten, solche verbindungen enthaltende medikamente und deren verwendung
JP5490014B2 (ja)	2007-12-11	2014-05-14	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (de)	2008-01-24	2012-12-19	Vitae Pharmaceuticals, Inc.	Cyclische carbazate und semicarbazide als inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
EP2254872A2 (de)	2008-02-15	2010-12-01	Vitae Pharmaceuticals, Inc.	Cycloalkyllactamderivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1
JP5538365B2 (ja)	2008-05-01	2014-07-02	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
CL2009001058A1 (es)	2008-05-01	2010-09-10	Vitae Pharmaceuticals Inc	Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
CA2722427A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009138386A2 (en)	2008-05-13	2009-11-19	Boehringer Ingelheim International Gmbh	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
JP5777030B2 (ja)	2008-07-25	2015-09-09	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	１１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
RU2539979C2 (ru)	2008-07-25	2015-01-27	Вайтаи Фармасьютиклз, Инк.	Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1
MA33216B1 (fr)	2009-04-30	2012-04-02	Boehringer Ingelheim Int	Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (de)	2009-06-11	2012-04-18	Vitae Pharmaceuticals, Inc.	Cyclische hemmer der 11beta-hydroxysteroiddehydrogenase 1 auf basis der 1,3 -oxazinan- 2 -on-struktur
TWI531571B (zh)	2009-11-06	2016-05-01	維它藥物公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (de)	2010-06-16	2016-09-14	Vitae Pharmaceuticals, Inc.	Substituierte 5-,6- und 7-gliedrige heterocyclen, medikamente mit derartigen verbindungen und ihre verwendung
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja)	2011-08-17	2014-09-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	インデノピリジン誘導体

1974
- 1974-03-09 DE DE2411382A patent/DE2411382C3/de not_active Expired
1975
- 1975-02-28 AT AT153875A patent/AT344332B/de not_active IP Right Cessation
- 1975-03-05 CH CH280275A patent/CH612425A5/xx not_active IP Right Cessation
- 1975-03-05 SU SU7502110984A patent/SU577982A3/ru active
- 1975-03-06 FI FI750652A patent/FI63571C/fi not_active IP Right Cessation
- 1975-03-07 DK DK92975A patent/DK137188C/da active
- 1975-03-07 IE IE505/75A patent/IE40945B1/xx unknown
- 1975-03-07 NL NL7502724A patent/NL7502724A/xx not_active Application Discontinuation
- 1975-03-07 BE BE154138A patent/BE826440A/xx not_active IP Right Cessation
- 1975-03-07 NO NO750773A patent/NO141800C/no unknown
- 1975-03-07 IL IL46760A patent/IL46760A/xx unknown
- 1975-03-07 SE SE7502592A patent/SE421919B/xx not_active IP Right Cessation
- 1975-03-07 RO RO7589654A patent/RO70051A/ro unknown
- 1975-03-07 BG BG030538A patent/BG24814A4/xx unknown
- 1975-03-07 JP JP50027915A patent/JPS5827275B2/ja not_active Expired
- 1975-03-07 ZA ZA751394A patent/ZA751394B/xx unknown
- 1975-03-07 DD DD184642A patent/DD119236A5/xx unknown
- 1975-03-07 RO RO7589653A patent/RO69617A/ro unknown
- 1975-03-07 HU HU75BO1536A patent/HU177408B/hu unknown
- 1975-03-07 BG BG030537A patent/BG24813A4/xx unknown
- 1975-03-07 GB GB9633/75A patent/GB1496418A/en not_active Expired
- 1975-03-07 FR FR7507239A patent/FR2262984B1/fr not_active Expired
- 1975-03-07 BG BG029183A patent/BG25087A3/xx unknown
- 1975-03-07 CA CA221,554A patent/CA1049511A/en not_active Expired
- 1975-03-08 PL PL1975191318A patent/PL93699B1/pl unknown
- 1975-03-08 PL PL1975191319A patent/PL93700B1/pl unknown
- 1975-03-08 PL PL1975178582A patent/PL93499B1/pl unknown
- 1975-03-10 PH PH16895A patent/PH14127A/en unknown
- 1975-03-10 CS CS751583A patent/CS188221B2/cs unknown
- 1975-08-20 ES ES440345A patent/ES440345A1/es not_active Expired
- 1975-08-20 ES ES440349A patent/ES440349A1/es not_active Expired
- 1975-08-20 ES ES440350A patent/ES440350A1/es not_active Expired
- 1975-08-20 ES ES440346A patent/ES440346A1/es not_active Expired
- 1975-08-20 ES ES440348A patent/ES440348A1/es not_active Expired
- 1975-08-20 ES ES440347A patent/ES440347A1/es not_active Expired
- 1975-12-19 SU SU752199295A patent/SU588916A3/ru active
- 1975-12-19 SU SU7502199294A patent/SU577983A3/ru active
1979
- 1979-04-24 CH CH384779A patent/CH622016A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384879A patent/CH620681A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384979A patent/CH622017A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384479A patent/CH622014A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384379A patent/CH620439A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384579A patent/CH622015A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384679A patent/CH620440A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI63571C (fi)	1983-07-11
DE2411382B2 (de)	1979-01-18
JPS50123675A (de)	1975-09-29
CH622017A5 (en)	1981-03-13
RO70051A (ro)	1980-12-30
CH620439A5 (en)	1980-11-28
BG24813A4 (bg)	1978-05-12
HU177408B (en)	1981-10-28
AU7894275A (en)	1976-09-16
CA1049511A (en)	1979-02-27
CH622014A5 (en)	1981-03-13
GB1496418A (en)	1977-12-30
DE2411382A1 (de)	1975-09-18
DD119236A5 (de)	1976-04-12
CS188221B2 (en)	1979-02-28
ES440348A1 (es)	1977-06-01
IL46760A (en)	1978-12-17
SU577982A3 (ru)	1977-10-25
IE40945B1 (en)	1979-09-12
ES440350A1 (es)	1977-03-16
ES440345A1 (es)	1977-03-01
FR2262984B1 (de)	1978-07-28
CH620440A5 (en)	1980-11-28
FI63571B (fi)	1983-03-31
ES440346A1 (es)	1977-03-01
BE826440A (fr)	1975-09-08
CH620681A5 (en)	1980-12-15
SU588916A3 (ru)	1978-01-15
IE40945L (en)	1975-09-09
PL93699B1 (de)	1977-06-30
PL93700B1 (de)	1977-06-30
BG24814A4 (bg)	1978-05-12
PL93499B1 (de)	1977-05-30
FI750652A7 (de)	1975-09-10
ZA751394B (en)	1976-11-24
NO141800C (no)	1980-06-04
NO750773L (de)	1975-09-10
BG25087A3 (bg)	1978-07-12
NO141800B (no)	1980-02-04
RO69617A (ro)	1980-08-15
ES440349A1 (es)	1977-03-01
JPS5827275B2 (ja)	1983-06-08
ES440347A1 (es)	1977-06-01
PH14127A (en)	1981-02-26
CH622016A5 (en)	1981-03-13
SU577983A3 (ru)	1977-10-25
SE421919B (sv)	1982-02-08
SE7502592L (de)	1975-09-10
DE2411382C3 (de)	1979-09-06
FR2262984A1 (de)	1975-10-03
DK92975A (de)	1975-09-10
IL46760A0 (en)	1975-05-22
DK137188B (da)	1978-01-30
NL7502724A (nl)	1975-09-11
DK137188C (da)	1978-07-03
AT344332B (de)	1978-07-10
CH612425A5 (en)	1979-07-31
CH622015A5 (en)	1981-03-13

Legal Events

Date	Code	Title	Description
1989-08-15	ELJ	Ceased due to non-payment of the annual fee
1999-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
AT342610B (de)	1978-04-10	Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze
AT344332B (de)	1978-07-10	Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen
AT335076B (de)	1977-02-25	Verfahren zur herstellung neuer n- (methoxymethyl-furyl-methyl) -6,7- benzomorphane und -morphinane und deren saureadditionssalzen
AT334900B (de)	1977-02-10	Verfahren zur herstellung neuer n-(-(omega-phenylalkyl)-piperidyl-4-)-n-(alfa-pyridyl)-carbonsaureamide und deren saureadditionssalze
AT334881B (de)	1977-02-10	Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze
AT330750B (de)	1976-07-12	Verfahren zur herstellung neuer 3- (p-alkylthioalkoxyphenoxy) -2-hydroxy-aminopropane und deren saureadditionssalze
ATA829876A (de)	1978-06-15	Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen
AT339281B (de)	1977-10-10	Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen
ATA559877A (de)	1978-11-15	Verfahren zur herstellung neuer 5,9-beta- disubstituierter 2-tetrahydrofurfuryl-6,7 benzomorphane und deren saeureadditionssalzen
ATA421177A (de)	1979-03-15	Verfahren zur herstellung neuer 2,6-di- subsitutierter 2-phenylimino-imidazolidine und deren saeureadditionssalze
AT341498B (de)	1978-02-10	Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze
AT341497B (de)	1978-02-10	Verfahren zur herstellung neuer 1-phenoxy-2-hydroxy-3-aminopropane und deren saureadditionssalze
AT340399B (de)	1977-12-12	Verfahren zur herstellung neuer aminobenzoesaurealkylester und deren saureadditionssalze
AT343112B (de)	1978-05-10	Verfahren zur herstellung neuer imidazol-1-alkylcarbonsaurederivate und ihrer salze
AT342611B (de)	1978-04-10	Verfahren zur herstellung neuer pyridazinderivate und deren saureadditionssalze
AT331227B (de)	1976-08-10	Verfahren zur herstellung neuer 3-(p-alkylthioalkoxy-phenoxy)-2-hydroxy-aminopropane und deren saureadditionssalze
ATA127275A (de)	1975-08-15	Verfahren zur herstellung neuer 3-(p-alkylthioalkoxy-phenoxy)-2-hydroxy-aminopropane und deren saureadditionssalze
ATA127375A (de)	1975-11-15	Verfahren zur herstellung neuer 3- (p-alkylthioalkoxy-phenoxy) -2-hydroxy-aminopropane und deren saureadditionssalze
ATA127675A (de)	1975-08-15	Verfahren zur herstellung neuer 3-(p-alkylthioalkoxy-phenoxy)-2-hydroxy-aminopropane und deren saureadditionssalze
ATA127475A (de)	1975-11-15	Verfahren zur herstellung neuer 3-(p-alkylthioalkoxy-phenoxy)-2-hydroxy-aminopropane und deren saureadditionssalze
ATA729676A (de)	1977-05-15	Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen