ATA211086A - Verfahren zur herstellung neuer cephalosporinsalze - Google Patents

Verfahren zur herstellung neuer cephalosporinsalze

Info

Publication number: ATA211086A
Authority: AT; Austria
Prior art keywords: salts; producing new; cephalosporine; new cephalosporine; producing
Prior art date: 1985-08-05

Application number

AT0211086A

Other languages

English (en)

Other versions

AT390957B (de

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-05

Filing date

1986-08-05

Publication date

1990-01-15

1986-08-05 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1989-05-23 Priority to AT1248/89A priority Critical patent/AT393452B/de

1990-01-15 Publication of ATA211086A publication Critical patent/ATA211086A/de

1990-07-25 Application granted granted Critical

1990-07-25 Publication of AT390957B publication Critical patent/AT390957B/de

Links

HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Medicinal Preparation (AREA)

AT0211086A 1985-08-05 1986-08-05 Verfahren zur herstellung neuer cephalosporinsalze AT390957B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT1248/89A AT393452B (de)	1985-08-05	1989-05-23	Verfahren zur herstellung eines cephalosporinpraeparates zur herstellung einer injektionsloesung

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US76223585A	1985-08-05	1985-08-05

Publications (2)

Publication Number	Publication Date
ATA211086A true ATA211086A (de)	1990-01-15
AT390957B AT390957B (de)	1990-07-25

Family

ID=25064475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0211086A AT390957B (de)	1985-08-05	1986-08-05	Verfahren zur herstellung neuer cephalosporinsalze

Country Status (34)

Country	Link
JP (1)	JPH0615548B2 (de)
KR (1)	KR930003121B1 (de)
AR (1)	AR243894A1 (de)
AT (1)	AT390957B (de)
AU (1)	AU597262B2 (de)
BE (1)	BE905219A (de)
CA (1)	CA1284994C (de)
CH (1)	CH675581A5 (de)
CS (2)	CS276717B6 (de)
CY (1)	CY1614A (de)
DD (2)	DD254941A5 (de)
DE (1)	DE3626375A1 (de)
DK (1)	DK162053C (de)
EG (1)	EG18003A (de)
ES (1)	ES2002112A6 (de)
FI (1)	FI84484C (de)
FR (1)	FR2585705B1 (de)
GB (1)	GB2179936B (de)
GR (1)	GR862055B (de)
HK (1)	HK99691A (de)
HU (1)	HU196602B (de)
IE (1)	IE59222B1 (de)
IL (1)	IL79608A (de)
IT (1)	IT1197067B (de)
LU (2)	LU88574I2 (de)
MY (1)	MY102212A (de)
NL (1)	NL8601991A (de)
OA (1)	OA08672A (de)
PT (1)	PT83134B (de)
SE (1)	SE469633B (de)
SG (1)	SG79791G (de)
SU (1)	SU1516013A3 (de)
YU (1)	YU45793B (de)
ZA (1)	ZA865842B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4883868A (en) *	1984-12-27	1989-11-28	Banyu Pharmaceutical Co., Ltd.	7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) *	1984-12-27	1990-09-25	Banyu Pharmaceutical Company, Ltd.	Crystalline cephalosporin compounds
US5244891A (en) *	1985-08-05	1993-09-14	Bristol-Myers Squibb Company	Injectable compositions of cefepime dihydrochloride hydrate
US4910301A (en) *	1985-08-05	1990-03-20	Bristol-Myers Company	Cefepime cephalosporin salts
US4808617A (en) *	1985-12-18	1989-02-28	Bristol-Myers Company	Lyophilized or precipitated cephalosporin zwitterion and salt combination
KR950010084B1 (ko) *	1987-06-25	1995-09-06	반유세이야꾸 가부시끼가이샤	결정성 세팔로스포린 화합물, 그의 제조법 및 그의 제조 중간체
JPH02101081A (ja) *	1988-10-08	1990-04-12	Meiji Seika Kaisha Ltd	セファロスポリン誘導体結晶性二塩酸塩及びその製造法
CA2011116C (en) *	1989-03-06	1999-11-16	Murray A. Kaplan	Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) *	1992-09-08	1994-03-09	Elizabeth A. Garofalo	Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
ATE202109T1 (de) *	1993-03-12	2001-06-15	Upjohn Co	Kristallines ceftiofur (freie säure)
EP0638573A1 (de) *	1993-08-10	1995-02-15	Lucky Ltd.	Kristalline Hydrate eines Cephalosporins und Verfahren zu ihrer Herstellung
ES2298850T3 (es)	2003-12-23	2008-05-16	Sandoz Gmbh	Proceso para la produccion de intermedios para utilizar en la sintesis de la cefalosporina.
WO2008056221A2 (en) *	2006-11-06	2008-05-15	Orchid Chemicals & Pharmaceuticals Limited	Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (de) *	2012-02-29	2013-08-29	Aicuris Gmbh & Co. Kg	Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151588A (en) *	1979-05-14	1980-11-26	Takeda Chem Ind Ltd	Preparation of cephalosporin salt crystal
CA1213882A (en) *	1982-03-04	1986-11-12	Jun Okumura	Cephalosporins
US4406899A (en) *	1982-03-04	1983-09-27	Bristol-Myers Company	Cephalosporins
US4525473A (en) *	1983-03-30	1985-06-25	Bristol-Myers Company	Cephalosporins
DE3419015A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von cephalosporinen
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds
GB2165245B (en) *	1984-10-01	1988-05-25	Glaxo Group Ltd	Chemical compounds

1986
- 1986-07-28 CA CA000514766A patent/CA1284994C/en not_active Expired - Lifetime
- 1986-07-28 FR FR8610892A patent/FR2585705B1/fr not_active Expired
- 1986-07-29 AR AR86304717A patent/AR243894A1/es active
- 1986-07-30 AU AU60694/86A patent/AU597262B2/en not_active Expired
- 1986-07-31 YU YU137186A patent/YU45793B/sh unknown
- 1986-08-01 IE IE207886A patent/IE59222B1/en not_active IP Right Cessation
- 1986-08-01 FI FI863155A patent/FI84484C/fi not_active IP Right Cessation
- 1986-08-04 JP JP61183288A patent/JPH0615548B2/ja not_active Expired - Lifetime
- 1986-08-04 DE DE19863626375 patent/DE3626375A1/de not_active Ceased
- 1986-08-04 GR GR862055A patent/GR862055B/el unknown
- 1986-08-04 ZA ZA865842A patent/ZA865842B/xx unknown
- 1986-08-04 SE SE8603308A patent/SE469633B/sv not_active IP Right Cessation
- 1986-08-04 DK DK371886A patent/DK162053C/da not_active IP Right Cessation
- 1986-08-04 BE BE07217010A patent/BE905219A/fr not_active IP Right Cessation
- 1986-08-04 LU LU88574C patent/LU88574I2/fr unknown
- 1986-08-04 CS CS865827A patent/CS276717B6/cs unknown
- 1986-08-04 GB GB8618989A patent/GB2179936B/en not_active Expired
- 1986-08-04 CH CH3117/86A patent/CH675581A5/de not_active IP Right Cessation
- 1986-08-04 LU LU86540A patent/LU86540A1/fr unknown
- 1986-08-04 CS CS903570A patent/CS276849B6/cs unknown
- 1986-08-04 SU SU864027914A patent/SU1516013A3/ru active
- 1986-08-04 PT PT83134A patent/PT83134B/pt unknown
- 1986-08-04 IT IT21409/86A patent/IT1197067B/it active Protection Beyond IP Right Term
- 1986-08-04 IL IL79608A patent/IL79608A/xx not_active IP Right Cessation
- 1986-08-04 NL NL8601991A patent/NL8601991A/nl not_active Application Discontinuation
- 1986-08-05 ES ES8600872A patent/ES2002112A6/es not_active Expired
- 1986-08-05 AT AT0211086A patent/AT390957B/de not_active IP Right Cessation
- 1986-08-05 OA OA58918A patent/OA08672A/xx unknown
- 1986-08-05 DD DD86293433A patent/DD254941A5/de unknown
- 1986-08-05 HU HU863376A patent/HU196602B/hu unknown
- 1986-08-05 KR KR1019860006445A patent/KR930003121B1/ko not_active Expired - Lifetime
1987
- 1987-09-29 MY MYPI87002279A patent/MY102212A/en unknown
1988
- 1988-03-30 DD DD88314213A patent/DD268395A5/de unknown
1989
- 1989-08-04 EG EG489/86A patent/EG18003A/xx active
1991
- 1991-10-02 SG SG797/91A patent/SG79791G/en unknown
- 1991-12-05 HK HK996/91A patent/HK99691A/xx not_active IP Right Cessation
1992
- 1992-07-10 CY CY1614A patent/CY1614A/en unknown

Also Published As

Publication number	Publication date
AU6069486A (en)	1987-02-12
LU88574I2 (fr)	1995-03-01
CA1284994C (en)	1991-06-18
FI863155A7 (fi)	1987-02-06
CS276717B6 (en)	1992-08-12
SU1516013A3 (ru)	1989-10-15
CY1614A (en)	1992-07-10
SE8603308D0 (sv)	1986-08-04
BE905219A (fr)	1987-02-04
IL79608A (en)	1991-07-18
CH675581A5 (de)	1990-10-15
LU86540A1 (fr)	1987-03-06
DK162053B (da)	1991-09-09
DD268395A5 (de)	1989-05-31
IE862078L (en)	1987-02-05
AR243894A1 (es)	1993-09-30
DE3626375A1 (de)	1987-02-12
IT1197067B (it)	1988-11-25
DK371886D0 (da)	1986-08-04
ZA865842B (en)	1987-04-29
AU597262B2 (en)	1990-05-31
FR2585705A1 (fr)	1987-02-06
PT83134A (en)	1986-09-01
FI84484C (fi)	1991-12-10
KR930003121B1 (ko)	1993-04-19
SE8603308L (sv)	1987-02-06
YU137186A (en)	1987-12-31
OA08672A (en)	1989-03-31
GB8618989D0 (en)	1986-09-17
YU45793B (sh)	1992-07-20
AT390957B (de)	1990-07-25
JPH0615548B2 (ja)	1994-03-02
KR880002530A (ko)	1988-05-09
JPS62103090A (ja)	1987-05-13
HUT41802A (en)	1987-05-28
SE469633B (sv)	1993-08-09
NL8601991A (nl)	1987-03-02
IL79608A0 (en)	1986-11-30
HK99691A (en)	1991-12-13
HU196602B (en)	1988-12-28
DK162053C (da)	1992-02-10
DK371886A (da)	1987-02-06
CS276849B6 (en)	1992-08-12
FI863155A0 (fi)	1986-08-01
GB2179936B (en)	1989-04-26
FR2585705B1 (fr)	1989-01-13
MY102212A (en)	1992-05-15
PT83134B (pt)	1989-07-31
FI84484B (fi)	1991-08-30
SG79791G (en)	1991-11-15
IT8621409A0 (it)	1986-08-04
GB2179936A (en)	1987-03-18
EG18003A (en)	1991-08-30
IT8621409A1 (it)	1988-02-04
DD254941A5 (de)	1988-03-16
ES2002112A6 (es)	1988-07-16
IE59222B1 (en)	1994-01-26
GR862055B (en)	1986-12-24

Legal Events

Date	Code	Title	Description
1995-03-15	SZA	Application filed for a certificate of protection	Free format text: SZ60/94, 941207
2000-04-15	EZF	Grant of a certificate of protection	Free format text: SZ 60/1994, 19941207, EXPIRES:20080629
2002-04-15	UEP	Publication of translation of european patent specification
2007-04-15	ELA	Expired due to lapse of time

Publication	Publication Date	Title
ATA115486A (de)	1993-06-15	Verfahren zur herstellung neuer antibiotischer makrolite
AT389302B (de)	1989-11-27	Verfahren zur herstellung neuer 3-benzylidencamphersulfonamidderivate
AT388735B (de)	1989-08-25	Verfahren zur herstellung neuer cephalosporinverbindungen
ATA232384A (de)	1990-07-15	Verfahren zur herstellung neuer 1,5-benzothiazepine
AT386208B (de)	1988-07-25	Verfahren zur herstellung neuer carbapenemzwischenverbindungen
DE3687954D1 (de)	1993-04-15	Verfahren zur herstellung eines tetraalkoxysilans.
ATA233086A (de)	1992-10-15	Verfahren zur herstellung neuer peptidantibiotika
ATA337185A (de)	1991-02-15	Verfahren zur herstellung neuer flavolignanderivate
ATA124285A (de)	1991-10-15	Verfahren zur herstellung neuer iminothiazolidinderivate
ATA335685A (de)	1991-10-15	Verfahren zur herstellung neuer thienopyridinderivate
ATA444982A (de)	1990-01-15	Verfahren zur herstellung neuer bisindolalkaloidderivate
ATA371584A (de)	1986-09-15	Verfahren zur herstellung neuer cephalosporanderivate
PT78488A (de)	1984-05-01	Verfahren zur herstellung neuer substituierter piperazin-1-ylessigsaeure-amide
ATA257386A (de)	1993-01-15	Verfahren zur herstellung neuer brenzcatechinderivate
ATA245286A (de)	1993-01-15	Verfahren zur herstellung neuer carbapenem-antibiotika
ATA215987A (de)	1991-11-15	Verfahren zur herstellung neuer chinazolinonverbindungen
ATA144386A (de)	1993-07-15	Verfahren zur herstellung von heparinsalzen
AT383810B (de)	1987-08-25	Verfahren zur herstellung von cephalosporinderivaten
AT383118B (de)	1987-05-25	Verfahren zur herstellung neuer azetidinonderivate
ATA59088A (de)	1992-10-15	Verfahren zur herstellung neuer cephalosporinverbindungen
ATA193885A (de)	1987-09-15	Verfahren zur herstellung neuer 3-amino-3-desoxy- d-glucosederivate
PT81374A (de)	1986-11-05	Verfahren zur herstellung neuer resorcinaether
ATA105584A (de)	1986-03-15	Verfahren zur herstellung von cephalosporinderivaten
ATA86285A (de)	1986-04-15	Verfahren zur herstellung neuer thiazolderivate
ATA292686A (de)	1991-07-15	Verfahren zur herstellung neuer quaternaerer aminthiolverbindungen