ATA82386A - Verfahren zur herstellung von neuen 7beta-(2-(2amino-4-thiazolyl)-alkenoylamino)-3-cephem-4- carbonsaeureestern - Google Patents

Verfahren zur herstellung von neuen 7beta-(2-(2amino-4-thiazolyl)-alkenoylamino)-3-cephem-4- carbonsaeureestern

Info

Publication number
ATA82386A
ATA82386A AT0082386A AT82386A ATA82386A AT A82386 A ATA82386 A AT A82386A AT 0082386 A AT0082386 A AT 0082386A AT 82386 A AT82386 A AT 82386A AT A82386 A ATA82386 A AT A82386A
Authority
AT
Austria
Prior art keywords
alkenoylamino
cephem
thiazolyl
amino
acid esters
Prior art date
Application number
AT0082386A
Other languages
English (en)
Other versions
AT392471B (de
Inventor
Yoshio Hamashima
Koji Ishikura
Kyoji Minami
Tadatoshi Kubota
Tadashi Yoshida
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Priority to AT0159089A priority Critical patent/AT397963B/de
Publication of ATA82386A publication Critical patent/ATA82386A/de
Application granted granted Critical
Publication of AT392471B publication Critical patent/AT392471B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT823/86A 1985-03-29 1986-03-27 Verfahren zur herstellung von neuen 7beta-(2-(2- amino-4-thiazolyl)-alkenoylamino)-3-cephem-4- carbonsaeureestern AT392471B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0159089A AT397963B (de) 1985-03-29 1989-06-28 Verfahren zur herstellung von neuen 7 beta-(2-(2- amino-4-thiazolyl)-alkenoylamimo)-3-cephem-4- carbonsäureestern

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6728085 1985-03-29

Publications (2)

Publication Number Publication Date
ATA82386A true ATA82386A (de) 1990-09-15
AT392471B AT392471B (de) 1991-04-10

Family

ID=13340398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT823/86A AT392471B (de) 1985-03-29 1986-03-27 Verfahren zur herstellung von neuen 7beta-(2-(2- amino-4-thiazolyl)-alkenoylamino)-3-cephem-4- carbonsaeureestern

Country Status (19)

Country Link
US (1) US4731361A (de)
JP (1) JPS6289A (de)
KR (1) KR870001983B1 (de)
AT (1) AT392471B (de)
AU (1) AU580855B2 (de)
BE (1) BE904517A (de)
BR (1) BR1100475A (de)
CA (1) CA1269655A (de)
CH (1) CH669600A5 (de)
DE (1) DE3610581A1 (de)
ES (2) ES8800237A1 (de)
FR (1) FR2579597B1 (de)
GB (1) GB2173194B (de)
GR (1) GR860838B (de)
HK (1) HK47993A (de)
IL (1) IL78301A (de)
IT (1) IT1191997B (de)
NL (1) NL192926C (de)
SU (3) SU1581223A3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
US5242913A (en) * 1987-03-11 1993-09-07 Pfizer Inc. Substituted 3-cephem compounds as antibacterial agents
NO891403L (no) * 1988-04-06 1989-10-09 Beecham Group Plc Nye forbindelser.
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
JP2002356427A (ja) * 2001-05-30 2002-12-13 Shionogi & Co Ltd β−ラクタマーゼ阻害剤
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
TWI364282B (en) * 2005-01-31 2012-05-21 Shionogi & Co Cefcapene pivoxil methanesulfonic acid salt
WO2008155615A2 (en) * 2007-06-18 2008-12-24 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of cephalosporin antibiotic
CN101747344B (zh) * 2009-12-22 2012-07-04 山东润泽制药有限公司 盐酸头孢卡品酯的合成方法
CN103087080B (zh) * 2011-11-03 2016-08-31 石药集团中奇制药技术（石家庄）有限公司 一种盐酸头孢卡品酯的制备方法及其合成中间体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575803A (en) * 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB2076801A (en) * 1980-04-14 1981-12-09 Erba Farmitalia alpha , beta -Disubstituted Acrylamido Cephalosporins
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
DE3145727A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen
CA1201431A (en) * 1981-12-17 1986-03-04 Daiei Tunemoto .beta.-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF
DE3239365A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
JPS5984890A (ja) * 1982-11-05 1984-05-16 Hisayasu Ishimaru 経口用セフアロスポリン化合物
DE3300593A1 (de) * 1983-01-11 1984-07-12 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
JPS6051193A (ja) * 1983-08-31 1985-03-22 Kyoto Yakuhin Kogyo Kk セフェム系化合物
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
DE3343208A1 (de) * 1983-11-30 1985-06-05 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
EP0187456A1 (de) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporinverbindungen

Also Published As

Publication number Publication date
US4731361A (en) 1988-03-15
ES553426A0 (es) 1987-11-01
GB8607855D0 (en) 1986-04-30
IT8667257A0 (it) 1986-03-28
HK47993A (en) 1993-05-27
DE3610581A1 (de) 1986-10-02
NL192926B (nl) 1998-01-05
KR860007266A (ko) 1986-10-10
ES8800237A1 (es) 1987-11-01
FR2579597B1 (fr) 1991-04-12
BE904517A (fr) 1986-07-16
CH669600A5 (de) 1989-03-31
IT1191997B (it) 1988-03-31
IL78301A0 (en) 1986-07-31
SU1556541A3 (ru) 1990-04-07
KR870001983B1 (ko) 1987-10-24
NL8600804A (nl) 1986-10-16
AT392471B (de) 1991-04-10
GB2173194A (en) 1986-10-08
FR2579597A1 (fr) 1986-10-03
ES557640A0 (es) 1988-03-16
JPS6289A (ja) 1987-01-06
CA1269655A (en) 1990-05-29
BR1100475A (pt) 1999-10-05
JPH0588715B2 (de) 1993-12-24
GB2173194B (en) 1989-06-28
IL78301A (en) 1991-07-18
AU5520486A (en) 1986-10-02
ES8801922A1 (es) 1988-03-16
DE3610581C2 (de) 1993-04-01
SU1581223A3 (ru) 1990-07-23
SU1575941A3 (ru) 1990-06-30
NL192926C (nl) 1998-05-07
AU580855B2 (en) 1989-02-02
GR860838B (en) 1986-07-29

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Legal Events

Date Code Title Description
ELA Expired due to lapse of time