ATE102926T1 - N,n'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazin verfahren zu dessen herstellung und dessen verwendung. - Google Patents

N,n'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazin verfahren zu dessen herstellung und dessen verwendung.

Info

Publication number
ATE102926T1
ATE102926T1 AT88500107T AT88500107T ATE102926T1 AT E102926 T1 ATE102926 T1 AT E102926T1 AT 88500107 T AT88500107 T AT 88500107T AT 88500107 T AT88500107 T AT 88500107T AT E102926 T1 ATE102926 T1 AT E102926T1
Authority
AT
Austria
Prior art keywords
dioxo
ethyl
preparation
bis
piperazine
Prior art date
Application number
AT88500107T
Other languages
English (en)
Inventor
Castellvi Juan Cabre
Meseguer Jose Diago
Bianchini Asunci N Esteve
Lenhardt Carlos E Padro
Pitarch Esteve Sans
Original Assignee
Gema Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gema Sa filed Critical Gema Sa
Application granted granted Critical
Publication of ATE102926T1 publication Critical patent/ATE102926T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
AT88500107T 1987-11-16 1988-11-07 N,n'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazin verfahren zu dessen herstellung und dessen verwendung. ATE102926T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES8703260A ES2005450A6 (es) 1987-11-16 1987-11-16 Procedimiento para la preparacion de derivados n(4-etil-2,3-dioxo)-piperacin-1-iln-carbonilo.
EP88500107A EP0317484B1 (de) 1987-11-16 1988-11-07 N,N'-Carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazin, Verfahren zu dessen Herstellung und dessen Verwendung

Publications (1)

Publication Number Publication Date
ATE102926T1 true ATE102926T1 (de) 1994-04-15

Family

ID=8253271

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88500107T ATE102926T1 (de) 1987-11-16 1988-11-07 N,n'-carboxyl-bis-(4-ethyl-2,3-dioxo)-piperazin verfahren zu dessen herstellung und dessen verwendung.

Country Status (7)

Country Link
US (2) US4965358A (de)
EP (1) EP0317484B1 (de)
JP (1) JP2693189B2 (de)
AT (1) ATE102926T1 (de)
CA (1) CA1338624C (de)
DE (1) DE3888458T2 (de)
ES (2) ES2005450A6 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2010104A6 (es) * 1989-01-26 1989-10-16 Gema Sa Procedimiento de preparacion de ureas asimetricas y utilizacion de las mismas.
IT1282955B1 (it) * 1996-05-03 1998-04-02 Abres Associated Biotechnology Processo per la preparazione di derivati ureidici e intermedi di sintesi
IT1283530B1 (it) * 1996-07-26 1998-04-21 Ribbon Srl Procedimento per la preparazione di penicilline
AU2002952259A0 (en) * 2002-10-25 2002-11-07 Silverbrook Research Pty Ltd Methods and apparatus
WO2002085855A1 (fr) 2001-04-19 2002-10-31 Eisai Co., Ltd. Derives de 2-iminopyrrolidine
ES2321153B1 (es) * 2007-10-11 2010-02-26 Astur Pharma S.A. Intermedio para la sintesis de piperacilina.
CN101508679B (zh) * 2009-03-31 2010-05-12 山西新天源医药化工有限公司 D(-)-α-(4-乙基-2,3-双氧哌嗪-1-甲酰胺基)对羟基苯乙酸的合成方法
CN105524001B (zh) * 2015-03-13 2018-04-06 山东艾孚特科技有限公司 一种n,n＇‑碳酰基‑双‑（4‑乙基‑2,3‑双氧哌嗪）的制备方法
CN104910178B (zh) * 2015-05-22 2017-06-13 华北制药集团先泰药业有限公司 一种哌拉西林酸的制备方法
CN109438476A (zh) * 2018-12-24 2019-03-08 常州红太阳药业有限公司 哌拉西林酸的制备方法
CN112321605B (zh) * 2020-11-04 2022-01-28 山东安信制药有限公司 一种哌拉西林的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092556A5 (de) * 1970-04-02 1972-01-21 Snam Progetti
US4110327A (en) * 1974-05-09 1978-08-29 Toyama Chemical Co., Ltd. 2,3 Diketo-piperazinocarbonylamino alkanoic acids and derivatives
DE2648858A1 (de) * 1975-10-30 1977-05-18 Cooper Lab Antimikrobielle verbindungen auf der grundlage von bis-carbamylguanidinoazaalkanen
DE2600880C2 (de) * 1976-01-12 1984-09-13 Toyama Chemical Co. Ltd., Tokio / Tokyo Cephalosporinverbindungen
JPS6026800B2 (ja) * 1976-01-22 1985-06-25 富山化学工業株式会社 新規な７α−メトキシセフアロスポリン類およびその製造法
US4200744A (en) * 1976-01-22 1980-04-29 Toyama Chemical Company, Limited Substituted 7α-methoxy-7β[(2,3-dioxo-1-piperazinyl)carbonylaminophenylacetamido]cephalosporins
JPS52106883A (en) * 1976-02-13 1977-09-07 Toyama Chem Co Ltd Novel penicillins and cephalosporins
JPS5618969A (en) * 1979-07-24 1981-02-23 Toyama Chem Co Ltd Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation
EP0131174B1 (de) * 1983-07-07 1989-09-13 Beecham Group Plc Substituierte Phenylglycin-Derivate von Beta-Lactam-Antibiotika

Also Published As

Publication number Publication date
EP0317484A3 (en) 1990-08-01
US5015736A (en) 1991-05-14
EP0317484B1 (de) 1994-03-16
DE3888458D1 (de) 1994-04-21
JP2693189B2 (ja) 1997-12-24
EP0317484A2 (de) 1989-05-24
DE3888458T2 (de) 1994-09-01
US4965358A (en) 1990-10-23
JPH01250367A (ja) 1989-10-05
CA1338624C (en) 1996-10-01
ES2005450A6 (es) 1989-03-01
ES2063058T3 (es) 1995-01-01

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Legal Events

Date Code Title Description
EEFA Change of the company name
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee