ATE104976T1 - Morpholinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents
Morpholinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE104976T1 ATE104976T1 AT9090403123T AT90403123T ATE104976T1 AT E104976 T1 ATE104976 T1 AT E104976T1 AT 9090403123 T AT9090403123 T AT 9090403123T AT 90403123 T AT90403123 T AT 90403123T AT E104976 T1 ATE104976 T1 AT E104976T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- pharmaceutical compositions
- compositions containing
- morpholine derivatives
- physiologically tolerable
- Prior art date
Links
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical class C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 150000002780 morpholines Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8914489A FR2653999A1 (fr) | 1989-11-06 | 1989-11-06 | Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104976T1 true ATE104976T1 (de) | 1994-05-15 |
Family
ID=9387096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT9090403123T ATE104976T1 (de) | 1989-11-06 | 1990-11-06 | Morpholinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5026701A (de) |
| EP (1) | EP0427605B1 (de) |
| JP (1) | JPH06102660B2 (de) |
| AT (1) | ATE104976T1 (de) |
| AU (1) | AU631465B2 (de) |
| CA (1) | CA2029334A1 (de) |
| DE (1) | DE69008489T2 (de) |
| DK (1) | DK0427605T3 (de) |
| ES (1) | ES2055887T3 (de) |
| FR (1) | FR2653999A1 (de) |
| IE (1) | IE66019B1 (de) |
| NZ (1) | NZ235815A (de) |
| OA (1) | OA09467A (de) |
| PT (1) | PT95782B (de) |
| ZA (1) | ZA908883B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698007A (en) * | 1992-08-06 | 1997-12-16 | Akzo Nobel Nv | Process for agglomerating particulate material |
| JP3411038B2 (ja) * | 1993-09-15 | 2003-05-26 | シンテックス(ユー・エス・エイ)・インコーポレイテッド | ミコフェノール酸モフェチルの結晶質無水物およびその静注用製剤 |
| US20040030131A1 (en) * | 2000-10-04 | 2004-02-12 | Martine Keenan | Pharmaceutical compounds |
| JP4185154B2 (ja) * | 2004-04-30 | 2008-11-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 中枢神経系障害治療用の置換モルホリン化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758766A (fr) * | 1969-11-17 | 1971-05-10 | Ici Ltd | Nouveaux derives de la morpholine et de la |
| FR2612926B1 (fr) * | 1987-03-24 | 1989-06-09 | Adir | Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
-
1989
- 1989-11-06 FR FR8914489A patent/FR2653999A1/fr active Granted
-
1990
- 1990-10-24 NZ NZ235815A patent/NZ235815A/en unknown
- 1990-10-25 US US07/603,522 patent/US5026701A/en not_active Expired - Fee Related
- 1990-11-05 AU AU65771/90A patent/AU631465B2/en not_active Ceased
- 1990-11-05 IE IE397290A patent/IE66019B1/en not_active IP Right Cessation
- 1990-11-05 PT PT95782A patent/PT95782B/pt not_active IP Right Cessation
- 1990-11-05 CA CA002029334A patent/CA2029334A1/fr not_active Abandoned
- 1990-11-06 DE DE69008489T patent/DE69008489T2/de not_active Expired - Fee Related
- 1990-11-06 JP JP2300917A patent/JPH06102660B2/ja not_active Expired - Lifetime
- 1990-11-06 ES ES90403123T patent/ES2055887T3/es not_active Expired - Lifetime
- 1990-11-06 DK DK90403123.4T patent/DK0427605T3/da active
- 1990-11-06 ZA ZA908883A patent/ZA908883B/xx unknown
- 1990-11-06 EP EP90403123A patent/EP0427605B1/de not_active Expired - Lifetime
- 1990-11-06 OA OA59884A patent/OA09467A/xx unknown
- 1990-11-06 AT AT9090403123T patent/ATE104976T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| OA09467A (fr) | 1992-11-15 |
| IE66019B1 (en) | 1995-11-29 |
| AU631465B2 (en) | 1992-11-26 |
| AU6577190A (en) | 1991-07-11 |
| FR2653999B1 (de) | 1994-04-22 |
| PT95782B (pt) | 1997-11-28 |
| ES2055887T3 (es) | 1994-09-01 |
| FR2653999A1 (fr) | 1991-05-10 |
| DE69008489D1 (de) | 1994-06-01 |
| CA2029334A1 (fr) | 1991-05-07 |
| IE903972A1 (en) | 1991-05-08 |
| EP0427605B1 (de) | 1994-04-27 |
| US5026701A (en) | 1991-06-25 |
| ZA908883B (en) | 1991-08-28 |
| NZ235815A (en) | 1992-04-28 |
| JPH06102660B2 (ja) | 1994-12-14 |
| EP0427605A1 (de) | 1991-05-15 |
| DE69008489T2 (de) | 1994-10-13 |
| JPH03184978A (ja) | 1991-08-12 |
| DK0427605T3 (da) | 1994-07-25 |
| PT95782A (pt) | 1991-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |