ATE105837T1 - Arylsulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen. - Google Patents
Arylsulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen.Info
- Publication number
- ATE105837T1 ATE105837T1 AT90902647T AT90902647T ATE105837T1 AT E105837 T1 ATE105837 T1 AT E105837T1 AT 90902647 T AT90902647 T AT 90902647T AT 90902647 T AT90902647 T AT 90902647T AT E105837 T1 ATE105837 T1 AT E105837T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- pharmaceutical compositions
- formula
- ring
- group
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898902407A GB8902407D0 (en) | 1989-02-03 | 1989-02-03 | Heterocyclic compounds |
| GB898902410A GB8902410D0 (en) | 1989-02-03 | 1989-02-03 | Bicyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE105837T1 true ATE105837T1 (de) | 1994-06-15 |
Family
ID=26294911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90902647T ATE105837T1 (de) | 1989-02-03 | 1990-02-01 | Arylsulphonylnitromethane, verfahren zu deren herstellung und pharmazeutische zusammensetzungen. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5185452A (de) |
| EP (1) | EP0409949B1 (de) |
| JP (1) | JPH04504250A (de) |
| AT (1) | ATE105837T1 (de) |
| AU (1) | AU631602B2 (de) |
| CA (1) | CA2025768A1 (de) |
| DE (1) | DE69008956D1 (de) |
| GR (1) | GR1000378B (de) |
| IL (1) | IL93178A0 (de) |
| NZ (1) | NZ232349A (de) |
| PT (1) | PT93052A (de) |
| WO (1) | WO1990008763A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11106381A (ja) * | 1997-09-30 | 1999-04-20 | Ss Pharmaceut Co Ltd | クロメン誘導体及びその塩並びにこれを含有する医薬 |
| US7620437B2 (en) * | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
| JP2011043839A (ja) * | 2010-09-29 | 2011-03-03 | Panasonic Corp | レジスト材料及びそれを用いたパターン形成方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1229653A (de) * | 1968-03-14 | 1971-04-28 | ||
| US3882247A (en) * | 1972-04-21 | 1975-05-06 | Du Pont | Fungicidal nitro organic sulfur compounds |
| US4053633A (en) * | 1976-06-24 | 1977-10-11 | The Dow Chemical Company | Aryl dibromonitromethyl sulfones |
| US4670470A (en) * | 1979-08-15 | 1987-06-02 | Merck & Co., Inc. | Allylsulfoxide enzyme inhibitors |
| US4309554A (en) * | 1980-04-28 | 1982-01-05 | The Dow Chemical Company | 3-(2-Thiophenesulfonyl)-2-halopropanenitriles |
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| DE3326635A1 (de) * | 1983-07-23 | 1985-01-31 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von monomethylsubstituierten methylen-verbindungen |
| GB8718619D0 (en) * | 1987-08-06 | 1987-09-09 | Ici Plc | Pharmaceutical compositions |
| GB8810203D0 (en) * | 1988-04-29 | 1988-06-02 | Ici Plc | Heterocyclic compounds |
-
1990
- 1990-01-25 IL IL93178A patent/IL93178A0/xx unknown
- 1990-02-01 WO PCT/GB1990/000164 patent/WO1990008763A1/en not_active Ceased
- 1990-02-01 AU AU50308/90A patent/AU631602B2/en not_active Ceased
- 1990-02-01 AT AT90902647T patent/ATE105837T1/de not_active IP Right Cessation
- 1990-02-01 DE DE69008956T patent/DE69008956D1/de not_active Expired - Lifetime
- 1990-02-01 CA CA002025768A patent/CA2025768A1/en not_active Abandoned
- 1990-02-01 JP JP2502694A patent/JPH04504250A/ja active Pending
- 1990-02-01 EP EP90902647A patent/EP0409949B1/de not_active Expired - Lifetime
- 1990-02-02 PT PT93052A patent/PT93052A/pt not_active Application Discontinuation
- 1990-02-02 NZ NZ232349A patent/NZ232349A/en unknown
- 1990-02-05 US US07/474,940 patent/US5185452A/en not_active Expired - Fee Related
- 1990-02-05 GR GR900100068A patent/GR1000378B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR1000378B (el) | 1992-06-30 |
| PT93052A (pt) | 1990-08-31 |
| JPH04504250A (ja) | 1992-07-30 |
| EP0409949B1 (de) | 1994-05-18 |
| US5185452A (en) | 1993-02-09 |
| GR900100068A (en) | 1991-06-28 |
| NZ232349A (en) | 1992-06-25 |
| IL93178A0 (en) | 1990-11-05 |
| AU5030890A (en) | 1990-08-24 |
| AU631602B2 (en) | 1992-12-03 |
| WO1990008763A1 (en) | 1990-08-09 |
| CA2025768A1 (en) | 1990-08-04 |
| DE69008956D1 (de) | 1994-06-23 |
| EP0409949A1 (de) | 1991-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |