ATE106870T1 - Verfahren zur trennung optischer isomere von derivaten des 1,4-dihydropyridins. - Google Patents
Verfahren zur trennung optischer isomere von derivaten des 1,4-dihydropyridins.Info
- Publication number
- ATE106870T1 ATE106870T1 AT90400096T AT90400096T ATE106870T1 AT E106870 T1 ATE106870 T1 AT E106870T1 AT 90400096 T AT90400096 T AT 90400096T AT 90400096 T AT90400096 T AT 90400096T AT E106870 T1 ATE106870 T1 AT E106870T1
- Authority
- AT
- Austria
- Prior art keywords
- radical
- carbon atoms
- optical isomers
- denotes
- separation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000003287 optical effect Effects 0.000 title abstract 2
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- -1 alkoxy radical Chemical class 0.000 abstract 9
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- XIPUIGPNIDKXJU-UHFFFAOYSA-N [CH]1CC1 Chemical compound [CH]1CC1 XIPUIGPNIDKXJU-UHFFFAOYSA-N 0.000 abstract 1
- BQIKRTGTPBOIMK-UHFFFAOYSA-N [O]C[O] Chemical compound [O]C[O] BQIKRTGTPBOIMK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8912323A FR2652083B1 (fr) | 1989-09-20 | 1989-09-20 | Nouveau procede de separation d'isomeres optiques des derives de la dihydro-1,4 pyridine. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE106870T1 true ATE106870T1 (de) | 1994-06-15 |
Family
ID=9385673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90400096T ATE106870T1 (de) | 1989-09-20 | 1990-01-15 | Verfahren zur trennung optischer isomere von derivaten des 1,4-dihydropyridins. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0419297B1 (de) |
| JP (1) | JPH03112965A (de) |
| AT (1) | ATE106870T1 (de) |
| AU (1) | AU618444B2 (de) |
| CA (1) | CA2007718A1 (de) |
| DE (1) | DE69009642T2 (de) |
| DK (1) | DK0419297T3 (de) |
| ES (1) | ES2057455T3 (de) |
| FR (1) | FR2652083B1 (de) |
| IE (1) | IE63293B1 (de) |
| NZ (1) | NZ232089A (de) |
| OA (1) | OA09436A (de) |
| PT (1) | PT92859B (de) |
| ZA (1) | ZA90231B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686879B1 (fr) * | 1992-02-05 | 1994-03-18 | Adir Cie | Nouveaux composes de 1,4-dihydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| HU221810B1 (hu) * | 1997-08-12 | 2003-01-28 | EGIS Gyógyszergyár Rt. | Eljárás amlodipin-bezilát előállítására és az eljárás intermedierjei |
| RU2142942C1 (ru) * | 1999-04-28 | 1999-12-20 | Дж. Б.Кемикалс энд Фармасьютикалс Лтд. | Способ получения монобензолсульфоната 3-этил-5-метилового эфира 2-[(2-аминоэтокси)метил]-4-(2-хлорфенил)-1,4-дигидро-6-метил-3,5-пиридинди карбоновой кислоты |
| RU2161156C1 (ru) * | 1999-06-01 | 2000-12-27 | Джи.Б.Кемикалс Энд Фармасьютикалс Лтд | Способ получения 3-этил-5-метиловый эфир 2-[2-(n-фталимидо)-этоксиметил]-4-(2-хлорфенил)-1,4-дигидро-6-метил-3,5- пиридиндикарбоновой кислоты |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
| FR2649395B1 (fr) * | 1989-07-04 | 1992-11-06 | Adir | Nouveau derive de la dihydro-1,4 pyridine denomme (-) i1(((amino-2 ethoxy)-2 ethoxy) methyli1) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent |
| FR2602231B1 (fr) * | 1986-08-04 | 1988-10-28 | Adir | Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
-
1989
- 1989-09-20 FR FR8912323A patent/FR2652083B1/fr not_active Expired - Fee Related
-
1990
- 1990-01-04 IE IE2890A patent/IE63293B1/en not_active IP Right Cessation
- 1990-01-12 NZ NZ232089A patent/NZ232089A/xx unknown
- 1990-01-12 AU AU47926/90A patent/AU618444B2/en not_active Ceased
- 1990-01-12 JP JP2003680A patent/JPH03112965A/ja active Pending
- 1990-01-12 OA OA59725A patent/OA09436A/xx unknown
- 1990-01-12 ZA ZA90231A patent/ZA90231B/xx unknown
- 1990-01-12 CA CA002007718A patent/CA2007718A1/fr not_active Abandoned
- 1990-01-12 PT PT92859A patent/PT92859B/pt not_active IP Right Cessation
- 1990-01-15 EP EP90400096A patent/EP0419297B1/de not_active Expired - Lifetime
- 1990-01-15 AT AT90400096T patent/ATE106870T1/de not_active IP Right Cessation
- 1990-01-15 ES ES90400096T patent/ES2057455T3/es not_active Expired - Lifetime
- 1990-01-15 DK DK90400096.5T patent/DK0419297T3/da active
- 1990-01-15 DE DE69009642T patent/DE69009642T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK0419297T3 (da) | 1994-10-31 |
| PT92859A (pt) | 1990-07-31 |
| ES2057455T3 (es) | 1994-10-16 |
| EP0419297B1 (de) | 1994-06-08 |
| EP0419297A1 (de) | 1991-03-27 |
| IE63293B1 (en) | 1995-04-05 |
| ZA90231B (en) | 1990-11-28 |
| PT92859B (pt) | 1995-12-29 |
| DE69009642T2 (de) | 1994-10-27 |
| OA09436A (fr) | 1992-10-15 |
| DE69009642D1 (de) | 1994-07-14 |
| FR2652083A1 (fr) | 1991-03-22 |
| NZ232089A (en) | 1991-09-25 |
| FR2652083B1 (fr) | 1992-01-24 |
| CA2007718A1 (fr) | 1991-03-20 |
| IE900028A1 (en) | 1991-03-27 |
| AU618444B2 (en) | 1991-12-19 |
| JPH03112965A (ja) | 1991-05-14 |
| AU4792690A (en) | 1991-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |