ATE108634T1 - Erregung der chemotaxe durch chemotaktische peptide. - Google Patents

Erregung der chemotaxe durch chemotaktische peptide.

Info

Publication number: ATE108634T1
Authority: AT; Austria
Prior art keywords: peptide; forming residue; chemotactic; biocompatible; integer
Prior art date: 1988-04-21

Application number

AT89905999T

Other languages

English (en)

Inventor

Dan W Urry

Marianna Long

Original Assignee

Uab Research Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-21

Filing date

1989-04-05

Publication date

1994-08-15

1989-04-05 Application filed by Uab Research Foundation filed Critical Uab Research Foundation

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE108634T1 publication Critical patent/ATE108634T1/de

Links

230000035605 chemotaxis Effects 0.000 title abstract 2
230000003399 chemotactic effect Effects 0.000 title 1
230000005284 excitation Effects 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
101710091342 Chemotactic peptide Proteins 0.000 abstract 3
PRQROPMIIGLWRP-BZSNNMDCSA-N chemotactic peptide Chemical compound CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 PRQROPMIIGLWRP-BZSNNMDCSA-N 0.000 abstract 3
COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 2
QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 1
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
QNAYBMKLOCPYGJ-UWTATZPHSA-N L-Alanine Natural products C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 1
ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
229960003767 alanine Drugs 0.000 abstract 1
125000000539 amino acid group Chemical group 0.000 abstract 1
210000004899 c-terminal region Anatomy 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
210000002889 endothelial cell Anatomy 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
210000002950 fibroblast Anatomy 0.000 abstract 1
230000009545 invasion Effects 0.000 abstract 1
229910021645 metal ion Inorganic materials 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
229960005190 phenylalanine Drugs 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/25—Peptides having up to 20 amino acids in a defined sequence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Dermatology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Materials For Medical Uses (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT89905999T 1988-04-21 1989-04-05 Erregung der chemotaxe durch chemotaktische peptide. ATE108634T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/184,147 US4976734A (en)	1985-10-31	1988-04-21	Stimulation of chemotaxis by chemotactic peptides

Publications (1)

Publication Number	Publication Date
ATE108634T1 true ATE108634T1 (de)	1994-08-15

Family

ID=22675755

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89905999T ATE108634T1 (de)	1988-04-21	1989-04-05	Erregung der chemotaxe durch chemotaktische peptide.

Country Status (6)

Country	Link
US (1)	US4976734A (de)
EP (1)	EP0366777B1 (de)
JP (1)	JPH03501574A (de)
AT (1)	ATE108634T1 (de)
DE (1)	DE68916900T2 (de)
WO (1)	WO1989010098A1 (de)

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AU663291B2 (en) *	1990-05-03	1995-10-05	New England Deaconess Hospital Corporation	Synthetic peptides for arterial imaging
WO1993011784A1 (en) *	1991-12-13	1993-06-24	Duke University	Methods for inhibition or stimulation of the inflammatory response
WO1995029647A2 (en)	1994-04-29	1995-11-09	Scimed Life Systems, Inc.	Stent with collagen
US6087552A (en) *	1994-11-15	2000-07-11	Sisters Of Providence Of Oregon	Method of producing fused biomaterials and tissue
US7001328B1 (en)	1994-11-15	2006-02-21	Kenton W. Gregory	Method for using tropoelastin and for producing tropoelastin biomaterials
US5989244A (en) *	1994-11-15	1999-11-23	Gregory; Kenton W.	Method of use of a sheet of elastin or elastin-based material
US6372228B1 (en)	1994-11-15	2002-04-16	Kenton W. Gregory	Method of producing elastin, elastin-based biomaterials and tropoelastin materials
US5972406A (en) *	1995-04-14	1999-10-26	Bioelastics Research Ltd.	Bioelastomers suitable as food product additives
US6004782A (en) *	1995-04-14	1999-12-21	Bioelastics Research Ltd.	Hyperexpression of bioelastic polypeptides
US5854387A (en) *	1995-04-14	1998-12-29	Bioelastics Research, Ltd.	Simple method for the purification of a bioelastic polymer
WO1998007750A1 (en) *	1996-08-22	1998-02-26	Children's Medical Center Corporation	Novel osteopontin derived chemotactic peptides and methods of use
GB9714276D0 (en)	1997-07-08	1997-09-10	Univ Dundee	Peptides and related compounds
US6113636A (en) *	1997-11-20	2000-09-05	St. Jude Medical, Inc.	Medical article with adhered antimicrobial metal
EP1056413A4 (de) *	1998-02-27	2003-08-20	Bioelastics Res Ltd	Injizierbare implantate zur vergrösserung und wiederherstellung von gewebe
US6903244B1 (en)	1999-02-26	2005-06-07	University Of Utah Research Foundation	Mice which are +/− or −/− for the elastin gene as models for vascular disease
US20050048614A1 (en) *	2000-06-13	2005-03-03	Children's Medical Center Corporation	Biosynthetic oncolytic molecules and uses therefor
US7198798B2 (en) *	2001-05-10	2007-04-03	University Of Washington	Methods and devices for promoting endothelial morphogenesis
AU2003228382A1 (en) *	2002-03-27	2003-10-13	University Of Utah Research Foundation	Elastin prevents occlusion of body vessels by vascular smooth muscle cells
EP1877078B1 (de) *	2005-02-25	2014-06-11	University of Utah Research Foundation	Tropoelastin zur förderung der endothelzellenadhäsion oder endothelzellenmigration
US8470967B2 (en)	2010-09-24	2013-06-25	Duke University	Phase transition biopolymers and methods of use
US10364451B2 (en)	2013-05-30	2019-07-30	Duke University	Polymer conjugates having reduced antigenicity and methods of using the same
US10392611B2 (en)	2013-05-30	2019-08-27	Duke University	Polymer conjugates having reduced antigenicity and methods of using the same
GB201400472D0 (en) *	2014-01-13	2014-02-26	Nordic Bioscience As	Biochemical Markers for pulmonary and other diseases
WO2016154530A1 (en)	2015-03-26	2016-09-29	Duke University	Targeted therapeutic agents comprising multivalent protein-biopolymer fusions
WO2017024182A1 (en)	2015-08-04	2017-02-09	Duke University	Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
US11752213B2 (en)	2015-12-21	2023-09-12	Duke University	Surfaces having reduced non-specific binding and antigenicity
WO2017210476A1 (en)	2016-06-01	2017-12-07	Duke University	Nonfouling biosensors
WO2018053201A1 (en)	2016-09-14	2018-03-22	Duke University	Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs
EP3515928B1 (de)	2016-09-23	2026-01-28	Duke University	Unstrukturierte nichtrepititive polypeptide mit lcst-verhalten
US11648200B2 (en)	2017-01-12	2023-05-16	Duke University	Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018213320A1 (en)	2017-05-15	2018-11-22	Duke University	Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
EP3658168A4 (de)	2017-06-30	2021-07-14	Duke University	Ordnung und unordnung als designprinzip für auf stimuli ansprechende biopolymernetzwerke
WO2019147954A1 (en)	2018-01-26	2019-08-01	Duke University	Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same
EP3788343B1 (de)	2018-04-30	2024-03-27	Duke University	Auf stimuli reagierende plattform zur abgabe von auf peg-like-polymer basierendem arzneimittel
US11649275B2 (en)	2018-08-02	2023-05-16	Duke University	Dual agonist fusion proteins
WO2020051541A1 (en)	2018-09-07	2020-03-12	Duke University	Nanoparticulate drug delivery systems
US11512314B2 (en)	2019-07-12	2022-11-29	Duke University	Amphiphilic polynucleotides
CN115894667A (zh) *	2022-12-30	2023-04-04	芜湖英特菲尔生物制品产业研究院有限公司	一种长效重组弹性蛋白、peg化长效重组弹性蛋白及其制备方法和应用

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US4578079A (en) *	1982-08-04	1986-03-25	La Jolla Cancer Research Foundation	Tetrapeptide
US4589881A (en) *	1982-08-04	1986-05-20	La Jolla Cancer Research Foundation	Polypeptide
US4605413A (en) *	1983-09-19	1986-08-12	The University Of Alabama At Birmingham	Stimulation of chemotaxis by chemotactic peptides
US4693718A (en) *	1985-10-31	1987-09-15	University Of Alabama In Birmingham	Stimulation of chemotaxis by chemotactic peptides

1988
- 1988-04-21 US US07/184,147 patent/US4976734A/en not_active Expired - Lifetime
1989
- 1989-04-05 WO PCT/US1989/001321 patent/WO1989010098A1/en not_active Ceased
- 1989-04-05 AT AT89905999T patent/ATE108634T1/de not_active IP Right Cessation
- 1989-04-05 JP JP1505813A patent/JPH03501574A/ja active Pending
- 1989-04-05 DE DE68916900T patent/DE68916900T2/de not_active Expired - Fee Related
- 1989-04-05 EP EP89905999A patent/EP0366777B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH03501574A (ja)	1991-04-11
EP0366777A4 (en)	1991-01-16
DE68916900D1 (de)	1994-08-25
DE68916900T2 (de)	1995-01-19
EP0366777B1 (de)	1994-07-20
US4976734A (en)	1990-12-11
WO1989010098A1 (en)	1989-11-02
EP0366777A1 (de)	1990-05-09

Legal Events

Date	Code	Title	Description
1995-02-15	UEP	Publication of translation of european patent specification
2001-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE68916900D1 (de)	1994-08-25	Erregung der chemotaxe durch chemotaktische peptide.
ATE442159T1 (de)	2009-09-15	Parathyroidhormon analoge
SE9100799L (sv)	1992-09-16	Rekombinant derivat av human faktor viii
ATE527364T1 (de)	2011-10-15	Polypeptide erhaltend eine modifizierte menschliche serum-albumin sekretions-pre-sequenz mit erhöhtem ausscheidungsertrag
ATE368053T1 (de)	2007-08-15	Antimikrobielle peptide
DK0910571T3 (da)	2005-10-31	Hidtil ukendte antiangiogene peptider, polynucleotider, der koder for samme, samt fremgangsmåder til inhibering af angiogenese
SG63621A1 (en)	1999-11-16	Cytotoxic t lymphocyte-inducing lipopeptides and use as vaccines
EP0751148A3 (de)	1997-07-02	D-Aminosäure Substituierungsanaloge von Magaininpeptiden
NZ592340A (en)	2012-12-21	A method for making a virus vaccine compising Replikin peptides
NO964959L (no)	1996-11-21	Nye peptider med immunmodulerende virkninger
ATE42308T1 (de)	1989-05-15	Pharmakologisch aktive peptide.
DE60313970D1 (de)	2007-07-05	Lineare kationische peptide mit fungizider wirksamkeit
CO5271650A1 (es)	2003-04-30	Peptidos modificados y peptidomimeticos para el uso en inmunoterapia
NO963851L (no)	1997-03-17	Biotinderivater
FR2575163B1 (fr)	1987-03-20	Tri- et tetrapeptides reduits inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant
ATE547424T1 (de)	2012-03-15	Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure
ATE108455T1 (de)	1994-07-15	Segmentierte polypeptid-bioelastomere zur modulierung des elastizitaetsmoduls.
GB1532181A (en)	1978-11-15	Pentapetides and a method of preparing them
AR009805A1 (es)	2000-05-03	Peptidos que contienen cisteina
CA2083286A1 (en)	1992-01-27	Recombinant fibrinogenases, preparation and use thereof
RU97117935A (ru)	1999-07-10	Свойства пептидов, стимулирующих рост
DK506283D0 (da)	1983-11-04	Peptider
ECSP003720A (es)	2001-05-23	Peptidos modificados y peptidomimeticos para el uso en inmunoterapia
TH1778A (th)	1984-09-03	สารคล้ายคลึง จี อาร์ เอฟ (grf)
RU2003130226A (ru)	2005-02-10	Применение белка uk114 или его фрагментов для лечения и предупреждения эндотоксического шока