ATE112159T1 - Osmotische vorrichtung für verzögerte freisetzung eines wirkstoffes. - Google Patents

Osmotische vorrichtung für verzögerte freisetzung eines wirkstoffes.

Info

Publication number
ATE112159T1
ATE112159T1 AT92906167T AT92906167T ATE112159T1 AT E112159 T1 ATE112159 T1 AT E112159T1 AT 92906167 T AT92906167 T AT 92906167T AT 92906167 T AT92906167 T AT 92906167T AT E112159 T1 ATE112159 T1 AT E112159T1
Authority
AT
Austria
Prior art keywords
active agent
environment
wall section
housing
agent formulation
Prior art date
Application number
AT92906167T
Other languages
English (en)
Inventor
Patrick S-L Wong
Felix Theeuwes
Steven D Larsen
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE112159T1 publication Critical patent/ATE112159T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Detergent Compositions (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92906167T 1991-01-30 1992-01-27 Osmotische vorrichtung für verzögerte freisetzung eines wirkstoffes. ATE112159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64827091A 1991-01-30 1991-01-30

Publications (1)

Publication Number Publication Date
ATE112159T1 true ATE112159T1 (de) 1994-10-15

Family

ID=24600130

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92906167T ATE112159T1 (de) 1991-01-30 1992-01-27 Osmotische vorrichtung für verzögerte freisetzung eines wirkstoffes.

Country Status (17)

Country Link
US (1) US5312388A (de)
EP (1) EP0569534B1 (de)
JP (1) JP3307929B2 (de)
KR (1) KR0183058B1 (de)
AT (1) ATE112159T1 (de)
AU (1) AU653793B2 (de)
CA (1) CA2098992A1 (de)
DE (1) DE69200476T2 (de)
DK (1) DK0569534T3 (de)
ES (1) ES2065178T3 (de)
FI (1) FI933397A0 (de)
IE (1) IE70328B1 (de)
MX (1) MX9200331A (de)
NZ (1) NZ241413A (de)
PT (1) PT100054A (de)
WO (1) WO1992013521A1 (de)
ZA (1) ZA92543B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5223265A (en) * 1992-01-10 1993-06-29 Alza Corporation Osmotic device with delayed activation of drug delivery
GB9223144D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Controlled release device
GB9223172D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Capsule construction
US5498255A (en) * 1993-08-17 1996-03-12 Alza Corporation Osmotic device for protracted pulsatile delivery of agent
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
AU5123396A (en) * 1995-04-03 1996-10-23 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition containing sucralfate
US5817335A (en) * 1995-05-26 1998-10-06 Alza Corporation Osmotic device with high drug loading and delayed activation of drug delivery
US5800422A (en) * 1995-06-02 1998-09-01 Alza Corporation Osmotic device with delayed activation of drug delivery and complete drug release
US5902605A (en) * 1996-04-18 1999-05-11 Alza Corporation Drug delivery device with minimal residual drug retention
CA2257946A1 (en) * 1996-06-24 1997-12-31 Merck & Co., Inc. A composition of enalapril and losartan
WO1999018159A1 (en) * 1997-10-06 1999-04-15 Alza Corporation Injection-moldable composition and article of manufacture comprising same
US6322819B1 (en) * 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
IL147826A0 (en) 1999-07-30 2002-08-14 Smithkline Beecham Plc Multi-component pharmaceutical dosage form
US20050079214A1 (en) * 1999-09-01 2005-04-14 John Cooker Oral delivery system and method for making same
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
EP1492509A1 (de) * 2001-12-18 2005-01-05 ALZA Corporation Verabreichungsform zur zeitvariierten wirkstofffreisetzung
US20030129236A1 (en) * 2001-12-20 2003-07-10 Heimlich John M. Multiple pulse extended release formulations of clindamycin
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US20050079220A1 (en) * 2003-07-31 2005-04-14 Betty Yu Osmotic engine & dosage form for controlled release of a liquid active agent formulation
TW200539903A (en) * 2004-03-12 2005-12-16 Smithkline Beecham Plc Pharmaceutical formulations
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
JP5084290B2 (ja) * 2007-02-06 2012-11-28 オリンパスメディカルシステムズ株式会社 管腔通過確認装置
WO2008113368A1 (en) * 2007-03-21 2008-09-25 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
CN101827571A (zh) * 2007-10-15 2010-09-08 葛兰素集团有限公司 用于释放一种或多种药物成分的多部分剂型的连接件及所得剂型
EP2209455A1 (de) 2007-10-15 2010-07-28 Glaxo Group Limited Kapselhüllen mit platten zur freisetzung pharmazeutischer zusammensetzungen
CN101827573A (zh) 2007-10-15 2010-09-08 葛兰素集团有限公司 已装填的连接件的制造装置和方法
JP5667874B2 (ja) * 2007-10-19 2015-02-12 ファイザー・プロダクツ・インク マルチコンパートメント容器
EP2055292A1 (de) * 2007-10-30 2009-05-06 Pfizer Products Inc. Mehrfach unterteilter Behälter
JP2012502883A (ja) * 2008-06-13 2012-02-02 グラクソ グループ リミテッド 医薬製剤
EP2720686A4 (de) * 2011-06-15 2014-12-17 Orient Pharma Co Ltd Mehrschichtige kapsel und herstellungsverfahren dafür
EP3302442B1 (de) 2015-06-03 2024-10-16 Triastek, Inc. Darreichungsform und verwendung davon
JP6195280B2 (ja) * 2015-12-18 2017-09-13 オリエント ファーマ シーオー.,エルティーディー. 多層カプセルおよびその製造方法
WO2017151983A1 (en) * 2016-03-02 2017-09-08 Taris Biomedical Llc Osmotic drug delivery devices and methods of making osmotic drug delivery devices
AU2017261372B2 (en) * 2016-05-05 2019-02-14 Triastek, Inc. Controlled release dosage form
AU2018212273B2 (en) 2017-01-26 2023-12-21 Triastek, Inc. Dosage forms of controlled release at specific gastrointestinal sites
EP4480495A3 (de) * 2017-07-10 2025-06-18 Gel Cap Technologies, LLC Kapsel mit dualer freisetzung und verfahren, vorrichtungen und systeme zu ihrer herstellung
CN111698983B (zh) 2018-01-09 2022-10-18 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
GB8903564D0 (en) * 1989-02-16 1989-04-05 Rashid Abdul Drug dispensing device
US5017381A (en) * 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system

Also Published As

Publication number Publication date
WO1992013521A1 (en) 1992-08-20
EP0569534B1 (de) 1994-09-28
DE69200476D1 (de) 1994-11-03
FI933397A7 (fi) 1993-07-29
PT100054A (pt) 1994-04-29
NZ241413A (en) 1994-12-22
CA2098992A1 (en) 1992-07-31
AU1339492A (en) 1992-09-07
DE69200476T2 (de) 1995-02-02
KR0183058B1 (ko) 1999-05-01
ES2065178T3 (es) 1995-02-01
ZA92543B (en) 1992-10-28
US5312388A (en) 1994-05-17
DK0569534T3 (da) 1995-04-10
FI933397L (fi) 1993-07-29
IE70328B1 (en) 1996-11-13
JPH06505263A (ja) 1994-06-16
EP0569534A1 (de) 1993-11-18
JP3307929B2 (ja) 2002-07-29
KR930702957A (ko) 1993-11-29
FI933397A0 (fi) 1993-07-29
AU653793B2 (en) 1994-10-13
IE920234A1 (en) 1992-07-29
MX9200331A (es) 1992-10-01

Similar Documents

Publication Publication Date Title
DE69200476D1 (de) Osmotische Vorrichtung für verzögerte Freisetzung eines Wirkstoffes.
PT97203A (pt) Sistema de dosagem osmotica para libertacao de farmacos liquidos
PT96337A (pt) Dispositivo distribuidor de longa duracao incluindo uma dose de carregamento
KR930701156A (ko) 경시적 약물 전달을 위한 제형
CA2124829A1 (en) Osmotic device with delayed activation of drug delivery
DE69625408D1 (de) Doppelfluidabgabeeinrichtung für Wirkstoffflüssigkeiten
DE3170085D1 (en) Agent dispenser with microporous releasing diffusor
ES2056487T3 (es) Distribuidor dosificador implantable.
SE7713119L (sv) Osmotiskt driven avgivningsanordning for aktivt medel och forfarande for dess framstellning
AR061005A2 (es) Forma cristalina a de 1-(2,6- difluorobencil)-1h-1,2,3- triazol-4-carboxamida, preparaciones farmaceuticas que las contienen y su uso para la preparacion de medicamentos
ES2190205T3 (es) Combinacion para el tratamiento de la dependencia del alcohol que contiene un antagonista opioide y un modulador del complejo receptor de nmda.
CO4930286A1 (es) Sistema de suministro osmotico y metodo para mejorar el arranque y desempeno de sistemas de suministro osmotico
BR0100163A (pt) Sistema de lubrificação
ES2124910T3 (es) Dispensador que contiene un agente hidrofobo.
ATE208188T1 (de) Osmotische vorrichtung mit hohem gehalt an wirkstoffen und verzögertem aktivieren der wirkstofffreisetzung
CA2109698A1 (en) Long-term delivery device including hydrophobic loading dose
NZ238867A (en) Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device
AU5883196A (en) Osmotic device with delayed activation of drug delivery and omplete drug release
CA2220301A1 (en) Osmotic device with delayed activation of drug delivery and complete drug release
GB2327610B (en) Macrolide compositions
ES1034904Y (es) Perfeccionamiento de dispositivo inyector de fluidos para uso medicinal.
ECSP961762A (es) Compuestos antibacterianos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee