ES2065178T3 - Dispositivo osmotico para el suministro retardado de un agente. - Google Patents

Dispositivo osmotico para el suministro retardado de un agente.

Info

Publication number
ES2065178T3
ES2065178T3 ES92906167T ES92906167T ES2065178T3 ES 2065178 T3 ES2065178 T3 ES 2065178T3 ES 92906167 T ES92906167 T ES 92906167T ES 92906167 T ES92906167 T ES 92906167T ES 2065178 T3 ES2065178 T3 ES 2065178T3
Authority
ES
Spain
Prior art keywords
receptacle
environment
active agent
wall section
compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92906167T
Other languages
English (en)
Inventor
Patrick S-L Wong
Felix Theeuwes
Steven D Larsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2065178T3 publication Critical patent/ES2065178T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Detergent Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN DISPOSITIVO DISTRIBUIDOR, ABSORBEDOR DE FLUIDOS (1) PARA EL SUMINISTRO INICIALMENTE RETARDADO DE UN AGENTE ACTIVO (20) A UN ENTORNO FLUIDO DE USO Y A UN METODO PARA LA UTILIZACION DEL DISPOSITIVO DISTRIBUIDOR. EL DISTRIBUIDOR CONSTA DE UN RECEPTACULO (12) QUE TIENE UNA PRIMERA SECCION DE PARED (14) Y UNA SEGUNDA SECCION DE PARED (16) COLOCADAS DE MANERA TELESCOPICA, DESLIZANTE UNA RESPECTO A LA OTRA, CUYO RECEPTACULO (12) MANTIENE SU INTEGRIDAD EN EL ENTORNO DE USO; UN COMPARTIMIENTO INTERNO (18) RODEADO Y DEFINIDO POR EL RECEPTACULO (12); POR LO MENOS UNA FORMULACION DE UN AGENTE ACTIVO (20) EN EL COMPARTIMIENTO; Y UN ELEMENTO DE EXPANSION (22) Y UNA CAMARA DE SEPARACION (24) EN EL COMPARTIMIENTO PARA SEPARAR LA PRIMERA Y LA SEGUNDA SECCION DE PARED (14, 16) DEL RECEPTACULO (12) TRAS EXPONERLO AL ENTORNO DE USO PARA EXPONER LAS FORMULACIONES DEL AGENTE ACTIVO (20) AL ENTORNO DE USO.
ES92906167T 1991-01-30 1992-01-27 Dispositivo osmotico para el suministro retardado de un agente. Expired - Lifetime ES2065178T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64827091A 1991-01-30 1991-01-30

Publications (1)

Publication Number Publication Date
ES2065178T3 true ES2065178T3 (es) 1995-02-01

Family

ID=24600130

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92906167T Expired - Lifetime ES2065178T3 (es) 1991-01-30 1992-01-27 Dispositivo osmotico para el suministro retardado de un agente.

Country Status (17)

Country Link
US (1) US5312388A (es)
EP (1) EP0569534B1 (es)
JP (1) JP3307929B2 (es)
KR (1) KR0183058B1 (es)
AT (1) ATE112159T1 (es)
AU (1) AU653793B2 (es)
CA (1) CA2098992A1 (es)
DE (1) DE69200476T2 (es)
DK (1) DK0569534T3 (es)
ES (1) ES2065178T3 (es)
FI (1) FI933397A0 (es)
IE (1) IE70328B1 (es)
MX (1) MX9200331A (es)
NZ (1) NZ241413A (es)
PT (1) PT100054A (es)
WO (1) WO1992013521A1 (es)
ZA (1) ZA92543B (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5223265A (en) * 1992-01-10 1993-06-29 Alza Corporation Osmotic device with delayed activation of drug delivery
GB9223172D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Capsule construction
GB9223144D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Controlled release device
US5498255A (en) * 1993-08-17 1996-03-12 Alza Corporation Osmotic device for protracted pulsatile delivery of agent
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
EP0823255A4 (en) * 1995-04-03 1999-01-27 Chugai Pharmaceutical Co Ltd Pharmaceutical composition containing sucralfate
US5817335A (en) * 1995-05-26 1998-10-06 Alza Corporation Osmotic device with high drug loading and delayed activation of drug delivery
US5800422A (en) * 1995-06-02 1998-09-01 Alza Corporation Osmotic device with delayed activation of drug delivery and complete drug release
US5902605A (en) * 1996-04-18 1999-05-11 Alza Corporation Drug delivery device with minimal residual drug retention
CA2257946A1 (en) * 1996-06-24 1997-12-31 Merck & Co., Inc. A composition of enalapril and losartan
WO1999018159A1 (en) * 1997-10-06 1999-04-15 Alza Corporation Injection-moldable composition and article of manufacture comprising same
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
BR0012869A (pt) 1999-07-30 2002-05-21 Smithkline Beecham Plc Forma de dosagem farmacêutica de componentes múltiplos
US20050079214A1 (en) * 1999-09-01 2005-04-14 John Cooker Oral delivery system and method for making same
US6669954B2 (en) 2000-01-25 2003-12-30 John R. Crison Controlled release of drugs
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
EP1492509A1 (en) * 2001-12-18 2005-01-05 ALZA Corporation Dosage form providing time-varying patterns of drug delivery
WO2003053420A1 (en) * 2001-12-20 2003-07-03 Pharmacia Corporation Multiple-pulse extended release formulations of clindamycin
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
CN1859897A (zh) * 2003-07-31 2006-11-08 阿尔扎公司 用于液态活性剂制剂控制释放的抗渗透的渗透装置和剂型
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
JP5084290B2 (ja) * 2007-02-06 2012-11-28 オリンパスメディカルシステムズ株式会社 管腔通過確認装置
EP2134328A1 (en) * 2007-03-21 2009-12-23 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
US8293159B2 (en) 2007-10-15 2012-10-23 Capsugel Belgium Method and apparatus for manufacturing filled linkers
JP2011500185A (ja) * 2007-10-15 2011-01-06 グラクソ グループ リミテッド １または複数の医薬組成物を放出するためのマルチパート剤形用リンカー、およびその得られた剤形
US8454992B2 (en) 2007-10-15 2013-06-04 Capsugel Belgium Nv Paneled capsule shells for release of pharmaceutical compositions
JP5667874B2 (ja) 2007-10-19 2015-02-12 ファイザー・プロダクツ・インク マルチコンパートメント容器
EP2055292A1 (en) * 2007-10-30 2009-05-06 Pfizer Products Inc. Multi-compartmented container
WO2009150228A2 (en) * 2008-06-13 2009-12-17 Glaxo Group Limited Pharmaceutical formulations
EP2720686A4 (en) * 2011-06-15 2014-12-17 Orient Pharma Co Ltd MULTILAYER CAPSULE AND MANUFACTURING METHOD THEREFOR
CA3254279A1 (en) 2015-06-03 2025-03-18 Triastek, Inc. PHARMACEUTICAL FORMS AND RELATED USES
JP6195280B2 (ja) * 2015-12-18 2017-09-13 オリエント ファーマ シーオー．，エルティーディー． 多層カプセルおよびその製造方法
WO2017151983A1 (en) * 2016-03-02 2017-09-08 Taris Biomedical Llc Osmotic drug delivery devices and methods of making osmotic drug delivery devices
CA3023278C (en) * 2016-05-05 2019-04-30 Triastek, Inc. Controlled release dosage form
KR20190107712A (ko) 2017-01-26 2019-09-20 트리아스텍 인코포레이티드 특정 위장 부위에서의 제어 방출의 투여 형태
NZ760633A (en) * 2017-07-10 2025-11-28 Gel Cap Tech Llc Dual release dosage form capsule and methods, devices and systems for making same
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455143A (en) * 1982-03-22 1984-06-19 Alza Corporation Osmotic device for dispensing two different medications
GB8903564D0 (en) * 1989-02-16 1989-04-05 Rashid Abdul Drug dispensing device
US5017381A (en) * 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system

Also Published As

Publication number Publication date
IE920234A1 (en) 1992-07-29
JP3307929B2 (ja) 2002-07-29
JPH06505263A (ja) 1994-06-16
CA2098992A1 (en) 1992-07-31
FI933397A7 (fi) 1993-07-29
PT100054A (pt) 1994-04-29
EP0569534A1 (en) 1993-11-18
ATE112159T1 (de) 1994-10-15
DE69200476D1 (de) 1994-11-03
ZA92543B (en) 1992-10-28
DK0569534T3 (da) 1995-04-10
KR0183058B1 (ko) 1999-05-01
US5312388A (en) 1994-05-17
DE69200476T2 (de) 1995-02-02
AU653793B2 (en) 1994-10-13
IE70328B1 (en) 1996-11-13
AU1339492A (en) 1992-09-07
FI933397L (fi) 1993-07-29
EP0569534B1 (en) 1994-09-28
NZ241413A (en) 1994-12-22
MX9200331A (es) 1992-10-01
KR930702957A (ko) 1993-11-29
FI933397A0 (fi) 1993-07-29
WO1992013521A1 (en) 1992-08-20

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