ATE113043T1 - 7-(3-(aminomethyl)-3-alkyl-1- pyrrolidinyl>chinolin-3-carbonsäure-derivate und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

7-(3-(aminomethyl)-3-alkyl-1- pyrrolidinyl>chinolin-3-carbonsäure-derivate und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE113043T1
ATE113043T1 AT87110879T AT87110879T ATE113043T1 AT E113043 T1 ATE113043 T1 AT E113043T1 AT 87110879 T AT87110879 T AT 87110879T AT 87110879 T AT87110879 T AT 87110879T AT E113043 T1 ATE113043 T1 AT E113043T1
Authority
AT
Austria
Prior art keywords
aminomethyl
pyrrolidinyl
alkyl
pharmaceutical compositions
compositions containing
Prior art date
Application number
AT87110879T
Other languages
English (en)
Inventor
John Michael Domagala
Susan Elizabeth Hagen
Joseph Peter Sanchez
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE113043T1 publication Critical patent/ATE113043T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
AT87110879T 1986-07-28 1987-07-27 7-(3-(aminomethyl)-3-alkyl-1- pyrrolidinyl>chinolin-3-carbonsäure-derivate und diese enthaltende pharmazeutische zusammensetzungen. ATE113043T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88999486A 1986-07-28 1986-07-28
US07/039,438 US4771055A (en) 1986-07-28 1987-04-21 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids

Publications (1)

Publication Number Publication Date
ATE113043T1 true ATE113043T1 (de) 1994-11-15

Family

ID=26716130

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87110879T ATE113043T1 (de) 1986-07-28 1987-07-27 7-(3-(aminomethyl)-3-alkyl-1- pyrrolidinyl>chinolin-3-carbonsäure-derivate und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (14)

Country Link
US (1) US4771055A (de)
EP (1) EP0255908B1 (de)
JP (2) JPH082896B2 (de)
KR (1) KR950008050B1 (de)
AT (1) ATE113043T1 (de)
AU (1) AU595631B2 (de)
CA (1) CA1324141C (de)
DE (1) DE3750668D1 (de)
DK (1) DK170799B1 (de)
FI (1) FI873248A7 (de)
NO (1) NO873125L (de)
NZ (1) NZ221021A (de)
PH (1) PH24681A (de)
PT (1) PT85411B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
EP0242789A3 (de) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Chinolinderivate und Verfahren zu ihrer Herstellung
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
EP0342675B1 (de) * 1988-05-19 1995-01-25 Chugai Seiyaku Kabushiki Kaisha Chinoloncarbonsäure-Derivate
US5103040A (en) * 1988-06-21 1992-04-07 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
US5104868A (en) * 1988-06-21 1992-04-14 Pfizer Inc. Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
WO1991016327A1 (en) 1990-04-18 1991-10-31 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactams
DE4104870A1 (de) * 1991-02-17 1992-08-27 Bayer Ag Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
TW252107B (de) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
EP0806421A4 (de) * 1995-01-24 1998-04-15 Hokuriku Pharmaceutical Derivate der chinolincarbonsäure
PT897919E (pt) * 1996-04-19 2004-11-30 Wakunaga Pharma Co Ltd Novos derivados do acido piridonacarboxilico ou seus sais e agentes anti-bacterianos contendo-os como ingrediente activo
TW425394B (en) * 1996-04-24 2001-03-11 Daiichi Seiyaku Co Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
PL1666477T3 (pl) 2003-09-10 2013-11-29 Kyorin Seiyaku Kk Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
JP5322927B2 (ja) * 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
EP0154780B1 (de) * 1984-01-26 1990-04-11 Abbott Laboratories Antibakterielle Chinolinderivate
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPH0670032B2 (ja) * 1984-11-22 1994-09-07 大日本製薬株式会社 アミノピロリジン誘導体、そのエステルおよびその塩

Also Published As

Publication number Publication date
AU7608387A (en) 1988-02-04
KR950008050B1 (ko) 1995-07-24
PH24681A (en) 1990-09-07
PT85411A (en) 1987-08-01
AU595631B2 (en) 1990-04-05
DK390587D0 (da) 1987-07-27
DK170799B1 (da) 1996-01-22
PT85411B (pt) 1990-06-29
JP2628541B2 (ja) 1997-07-09
EP0255908B1 (de) 1994-10-19
FI873248L (fi) 1988-01-29
JPS6379885A (ja) 1988-04-09
EP0255908A3 (en) 1989-10-25
JPH082896B2 (ja) 1996-01-17
DE3750668D1 (de) 1994-11-24
FI873248A0 (fi) 1987-07-24
US4771055A (en) 1988-09-13
DK390587A (da) 1988-01-29
KR880001633A (ko) 1988-04-25
EP0255908A2 (de) 1988-02-17
CA1324141C (en) 1993-11-09
NO873125L (no) 1988-01-29
FI873248A7 (fi) 1988-01-29
NO873125D0 (no) 1987-07-27
NZ221021A (en) 1991-06-25
JPH08169876A (ja) 1996-07-02

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