ATE120797T1 - Phosphorylierte plasminogenaktivatoren. - Google Patents

Phosphorylierte plasminogenaktivatoren.

Info

Publication number
ATE120797T1
ATE120797T1 AT90907178T AT90907178T ATE120797T1 AT E120797 T1 ATE120797 T1 AT E120797T1 AT 90907178 T AT90907178 T AT 90907178T AT 90907178 T AT90907178 T AT 90907178T AT E120797 T1 ATE120797 T1 AT E120797T1
Authority
AT
Austria
Prior art keywords
phosphorylated
plasminogen activator
pro
unphosphorylated
plasminogen activators
Prior art date
Application number
AT90907178T
Other languages
English (en)
Inventor
Francesco Blasi
Maria Patrizia Stoppelli
Maria Rosaria Mastronicola
Karen Gjersing Welinder
Isabel Correas
Original Assignee
Francesco Blasi
Maria Patrizia Stoppelli
Maria Rosaria Mastronicola
Karen Gjersing Welinder
Isabel Correas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francesco Blasi, Maria Patrizia Stoppelli, Maria Rosaria Mastronicola, Karen Gjersing Welinder, Isabel Correas filed Critical Francesco Blasi
Application granted granted Critical
Publication of ATE120797T1 publication Critical patent/ATE120797T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT90907178T 1989-04-14 1990-04-11 Phosphorylierte plasminogenaktivatoren. ATE120797T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK182289A DK182289D0 (da) 1989-04-14 1989-04-14 Modifikation af proteiner

Publications (1)

Publication Number Publication Date
ATE120797T1 true ATE120797T1 (de) 1995-04-15

Family

ID=8108312

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90907178T ATE120797T1 (de) 1989-04-14 1990-04-11 Phosphorylierte plasminogenaktivatoren.

Country Status (16)

Country Link
US (2) US5416006A (de)
EP (1) EP0422198B1 (de)
JP (1) JPH03505530A (de)
KR (1) KR920700285A (de)
AT (1) ATE120797T1 (de)
AU (1) AU623522B2 (de)
CA (1) CA2031210A1 (de)
DE (1) DE69018361T2 (de)
DK (1) DK182289D0 (de)
ES (1) ES2072432T3 (de)
HU (1) HUT56130A (de)
IL (1) IL94070A0 (de)
NZ (1) NZ233321A (de)
PT (1) PT93755A (de)
WO (1) WO1990012872A1 (de)
ZA (1) ZA902747B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960702846A (ko) * 1993-05-28 1996-05-23 로버트 피. 블랙버언 우로키나제 리셉터 활성의 펩티드 저해인자(peptide inhbitors of urokinase receptor activity)
US6248715B1 (en) * 1993-06-01 2001-06-19 Chiron Corporation Method of treating a urokinase-type plasminogen activator-mediated disorder
FI955721L (fi) 1993-06-01 1995-11-27 Chiron Corp Urokinaasityyppisen plasminogeenin aktivaattorin inhibiittoreiden ilmentämiseksi
US6936587B1 (en) * 1997-07-25 2005-08-30 Angstrom Pharmaceuticals, Inc. Anti-invasive and anti-angiogenic compositions
US5994309A (en) * 1997-07-25 1999-11-30 Angstrom Pharmaceuticals, Inc. Anti-invasive and anti-angiogenic compositions and methods
WO2003065031A1 (en) * 2002-01-31 2003-08-07 Gl Sciences Incorporated Method and apparatus for analyzing amino acid, peptide, protein, saccharide or lipid
RU2216348C1 (ru) * 2002-11-14 2003-11-20 Общество с ограниченной ответственностью "Научно-производственное предприятие "Техноген" Фармацевтическая композиция, обладающая тромболитическим и фибринолитическим действием

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3663030D1 (en) * 1985-02-07 1989-06-01 Kowa Co Monoclonal antibodies to tissue plasminogen activator derived from human normal cells
GB8623823D0 (en) * 1986-10-03 1986-11-05 Sandoz Ltd Therapeutic lysis of fibrin blood clots

Also Published As

Publication number Publication date
IL94070A0 (en) 1991-01-31
AU623522B2 (en) 1992-05-14
KR920700285A (ko) 1992-02-19
US5416006A (en) 1995-05-16
HUT56130A (en) 1991-07-29
DE69018361T2 (de) 1995-08-31
AU5541190A (en) 1990-11-16
DE69018361D1 (de) 1995-05-11
US5688503A (en) 1997-11-18
EP0422198A1 (de) 1991-04-17
PT93755A (pt) 1990-11-20
ZA902747B (en) 1991-01-30
DK182289D0 (da) 1989-04-14
EP0422198B1 (de) 1995-04-05
NZ233321A (en) 1991-09-25
ES2072432T3 (es) 1995-07-16
WO1990012872A1 (en) 1990-11-01
JPH03505530A (ja) 1991-12-05
CA2031210A1 (en) 1990-10-15

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