ATE121095T1 - Substituierte aminoalkylphosphinsäure. - Google Patents

Substituierte aminoalkylphosphinsäure.

Info

Publication number: ATE121095T1
Authority: AT; Austria
Prior art keywords: denotes; hydrogen; substituted; halogen; hydroxy
Prior art date: 1989-05-13

Application number

AT90810346T

Other languages

English (en)

Inventor

Roger Graham Dr Hall

Ludwig Dr Maier

Wolfgang Dr Froestl

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-13

Filing date

1990-05-08

Publication date

1995-04-15

1990-05-08 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1995-04-15 Application granted granted Critical

1995-04-15 Publication of ATE121095T1 publication Critical patent/ATE121095T1/de

Links

239000002253 acid Substances 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
206010013754 Drug withdrawal syndrome Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000008238 Muscle Spasticity Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
206010008129 cerebral palsy Diseases 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
201000006417 multiple sclerosis Diseases 0.000 abstract 1
208000004296 neuralgia Diseases 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000018198 spasticity Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Luminescent Compositions (AREA)
Detergent Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT90810346T 1989-05-13 1990-05-08 Substituierte aminoalkylphosphinsäure. ATE121095T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898911017A GB8911017D0 (en)	1989-05-13	1989-05-13	Substituted aminoalkylphosphinic acids

Publications (1)

Publication Number	Publication Date
ATE121095T1 true ATE121095T1 (de)	1995-04-15

Family

ID=10656689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90810346T ATE121095T1 (de)	1989-05-13	1990-05-08	Substituierte aminoalkylphosphinsäure.

Country Status (24)

Country	Link
EP (1)	EP0399949B1 (de)
JP (1)	JP2930366B2 (de)
KR (1)	KR0159501B1 (de)
AT (1)	ATE121095T1 (de)
AU (1)	AU629335B2 (de)
CA (1)	CA2016631C (de)
DD (1)	DD294265A5 (de)
DE (1)	DE69018514T2 (de)
DK (1)	DK0399949T3 (de)
ES (1)	ES2070303T3 (de)
FI (1)	FI94416C (de)
GB (1)	GB8911017D0 (de)
GR (1)	GR3015770T3 (de)
HR (1)	HRP940178A2 (de)
HU (1)	HU206885B (de)
IE (1)	IE66165B1 (de)
IL (1)	IL94317A (de)
MX (1)	MX20639A (de)
NO (1)	NO176761C (de)
NZ (1)	NZ233647A (de)
PT (1)	PT94014B (de)
SI (1)	SI9010917B (de)
YU (1)	YU91790A (de)
ZA (1)	ZA903611B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0767174A1 (de) *	1991-11-21	1997-04-09	Ciba-Geigy Ag	Neue Aminoalkanphosphinsäuren und ihre Salze
EP0934061B3 (de)	1996-07-24	2015-01-21	Warner-Lambert Company LLC	Isobutylgaba und dessen derivate zur schmerzbehandlung
SK662001A3 (en)	1998-07-15	2001-10-08	Hassan Jomaa	Phosphorous organic compounds and their use
GB9906882D0 (en) *	1999-03-25	1999-05-19	Novartis Ag	Organic compounds
US7319095B2 (en)	1999-12-09	2008-01-15	Astrazeneca Ab	Use of GABAB receptor agonists
SE9904508D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
SE9904507D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
SE0102055D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Compounds
AR033779A1 (es)	2001-06-08	2004-01-07	Astrazeneca Ab	Compuestos utiles en la enfermedad de reflujo
PT1691811E (pt)	2003-12-11	2014-10-30	Sunovion Pharmaceuticals Inc	Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
SE0401653D0 (sv)	2004-06-24	2004-06-24	Astrazeneca Ab	New compounds
AU2006327315A1 (en)	2005-12-23	2007-06-28	Astrazeneca Ab	Imidazole derivatives for the treatment of gastrointestinal disorders
AU2006327317B2 (en)	2005-12-23	2010-11-25	Astrazeneca Ab	GABA-B receptor modulators
DE102008056228A1 (de) *	2008-11-06	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) *	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en)	2010-03-17	2011-09-22	INSERM (Institut National de la Santé et de la Recherche Médicale)	Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
CN107050456B (zh)	2010-09-28	2022-08-12	加利福尼亚大学董事会	治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3311475C1 (de) *	1983-03-29	1984-08-16	Siemens AG, 1000 Berlin und 8000 München	Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) *	1983-04-02	1984-10-04	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) *	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
GB8820266D0 (en) *	1988-08-26	1988-09-28	Smith Kline French Lab	Compounds

1989
- 1989-05-13 GB GB898911017A patent/GB8911017D0/en active Pending
1990
- 1990-05-07 IL IL94317A patent/IL94317A/xx not_active IP Right Cessation
- 1990-05-07 AU AU54809/90A patent/AU629335B2/en not_active Ceased
- 1990-05-08 ES ES90810346T patent/ES2070303T3/es not_active Expired - Lifetime
- 1990-05-08 AT AT90810346T patent/ATE121095T1/de not_active IP Right Cessation
- 1990-05-08 DK DK90810346.8T patent/DK0399949T3/da active
- 1990-05-08 EP EP90810346A patent/EP0399949B1/de not_active Expired - Lifetime
- 1990-05-08 DE DE69018514T patent/DE69018514T2/de not_active Expired - Fee Related
- 1990-05-09 MX MX2063990A patent/MX20639A/es unknown
- 1990-05-10 YU YU91790A patent/YU91790A/sh unknown
- 1990-05-10 SI SI9010917A patent/SI9010917B/sl unknown
- 1990-05-11 ZA ZA903611A patent/ZA903611B/xx unknown
- 1990-05-11 FI FI902368A patent/FI94416C/fi not_active IP Right Cessation
- 1990-05-11 NZ NZ233647A patent/NZ233647A/en unknown
- 1990-05-11 HU HU903012A patent/HU206885B/hu not_active IP Right Cessation
- 1990-05-11 KR KR1019900006687A patent/KR0159501B1/ko not_active Expired - Fee Related
- 1990-05-11 PT PT94014A patent/PT94014B/pt not_active IP Right Cessation
- 1990-05-11 NO NO902109A patent/NO176761C/no not_active IP Right Cessation
- 1990-05-11 CA CA002016631A patent/CA2016631C/en not_active Expired - Lifetime
- 1990-05-11 DD DD90340576A patent/DD294265A5/de not_active IP Right Cessation
- 1990-05-11 IE IE171690A patent/IE66165B1/en not_active IP Right Cessation
- 1990-05-14 JP JP2121395A patent/JP2930366B2/ja not_active Expired - Fee Related
1994
- 1994-03-18 HR HRP-917/90A patent/HRP940178A2/hr not_active Application Discontinuation
1995
- 1995-04-13 GR GR950400747T patent/GR3015770T3/el unknown

Also Published As

Publication number	Publication date
GB8911017D0 (en)	1989-06-28
HRP940178A2 (en)	1996-08-31
IE901716L (en)	1990-11-13
GR3015770T3 (en)	1995-07-31
NO176761B (no)	1995-02-13
YU91790A (sh)	1992-07-20
DD294265A5 (de)	1991-09-26
AU629335B2 (en)	1992-10-01
IL94317A0 (en)	1991-03-10
NO902109D0 (no)	1990-05-11
NO176761C (no)	1995-05-24
IL94317A (en)	1997-07-13
KR0159501B1 (ko)	1999-01-15
AU5480990A (en)	1990-11-15
ZA903611B (en)	1991-02-27
DK0399949T3 (da)	1995-07-03
NO902109L (no)	1990-11-14
FI902368A0 (fi)	1990-05-11
SI9010917B (sl)	1999-10-31
HU903012D0 (en)	1990-09-28
DE69018514T2 (de)	1995-09-21
NZ233647A (en)	1992-08-26
MX20639A (es)	1993-12-01
JP2930366B2 (ja)	1999-08-03
HUT53656A (en)	1990-11-28
PT94014B (pt)	1996-12-31
SI9010917A (en)	1997-06-30
KR900018124A (ko)	1990-12-20
CA2016631C (en)	2000-08-29
JPH0395195A (ja)	1991-04-19
HU206885B (en)	1993-01-28
EP0399949B1 (de)	1995-04-12
EP0399949A1 (de)	1990-11-28
FI94416B (fi)	1995-05-31
CA2016631A1 (en)	1990-11-13
PT94014A (pt)	1991-01-08
IE66165B1 (en)	1995-12-13
DE69018514D1 (de)	1995-05-18
FI94416C (fi)	1995-09-11
ES2070303T3 (es)	1995-06-01

Legal Events

Date	Code	Title	Description
2010-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69018514D1 (de)	1995-05-18	Substituierte Aminoalkylphosphinsäure.
BG49275A3 (en)	1991-09-16	Method for preparing diazobicycloalkylchinolin carbonate acids
IT1256345B (it)	1995-12-01	Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
MX9203744A (es)	1992-09-01	Analogos de camptotecina solubles en agua utiles para inhibir el crecimiento de celulas de tumor de animal.
EP0747383A3 (de)	1996-12-18	Clavulansäure Polyaminsalze
ATE109149T1 (de)	1994-08-15	3-pyrrolidinylthio-1-azabicyclo(3.2.0>-hept-2-e - 2-carbonsäureverbindungen.
ATE150462T1 (de)	1997-04-15	Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung
PT74356B (en)	1984-05-30	Process for the preparation of 2-penem
WO1987004926A3 (en)	1988-05-19	Method of modifying the lipid structure of cell membranes and pharmaceutical compositions for use therein
TW355705B (en)	1999-04-11	Substituted benzyloxycarbonylguanidines, process for their preparation, their medical use and pharmaceutical composition containing them
NO852514L (no)	1985-12-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-alkyltio-2-piperazino-pyrimido (5,4-d) pyrimidin-derivater.
HUT46214A (en)	1988-10-28	Process for producing medical preparation suitable for treatment of peptic ulcer
DE3782548D1 (de)	1992-12-17	Ergolin-ester, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DK634686A (da)	1987-07-01	Dioxahexensyrer, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse
ATE56705T1 (de)	1990-10-15	Piperidinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.