ZA903611B - Substituted aminoalkylphosphinic acids - Google Patents

Substituted aminoalkylphosphinic acids

Info

Publication number: ZA903611B
Authority: ZA; South Africa
Prior art keywords: denotes; hydrogen; halogen; hydroxy; methyl group
Prior art date: 1989-05-13

Application number

ZA903611A

Other languages

English (en)

Inventor

Roger Graham Hall

Graham Hall Roger

Ludwig Maier

Maier Ludwig

Wolfgang Froestl

Froestl Wolfgang

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-13

Filing date

1990-05-11

Publication date

1991-02-27

1990-05-11 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1991-02-27 Publication of ZA903611B publication Critical patent/ZA903611B/xx

Links

239000002253 acid Substances 0.000 title abstract 2
150000007513 acids Chemical class 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
206010013754 Drug withdrawal syndrome Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000008238 Muscle Spasticity Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
206010008129 cerebral palsy Diseases 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
201000006417 multiple sclerosis Diseases 0.000 abstract 1
208000004296 neuralgia Diseases 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000018198 spasticity Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Luminescent Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Detergent Compositions (AREA)

ZA903611A 1989-05-13 1990-05-11 Substituted aminoalkylphosphinic acids ZA903611B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898911017A GB8911017D0 (en)	1989-05-13	1989-05-13	Substituted aminoalkylphosphinic acids

Publications (1)

Publication Number	Publication Date
ZA903611B true ZA903611B (en)	1991-02-27

Family

ID=10656689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA903611A ZA903611B (en)	1989-05-13	1990-05-11	Substituted aminoalkylphosphinic acids

Country Status (24)

Country	Link
EP (1)	EP0399949B1 (de)
JP (1)	JP2930366B2 (de)
KR (1)	KR0159501B1 (de)
AT (1)	ATE121095T1 (de)
AU (1)	AU629335B2 (de)
CA (1)	CA2016631C (de)
DD (1)	DD294265A5 (de)
DE (1)	DE69018514T2 (de)
DK (1)	DK0399949T3 (de)
ES (1)	ES2070303T3 (de)
FI (1)	FI94416C (de)
GB (1)	GB8911017D0 (de)
GR (1)	GR3015770T3 (de)
HR (1)	HRP940178A2 (de)
HU (1)	HU206885B (de)
IE (1)	IE66165B1 (de)
IL (1)	IL94317A (de)
MX (1)	MX20639A (de)
NO (1)	NO176761C (de)
NZ (1)	NZ233647A (de)
PT (1)	PT94014B (de)
SI (1)	SI9010917B (de)
YU (1)	YU91790A (de)
ZA (1)	ZA903611B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0767174A1 (de) *	1991-11-21	1997-04-09	Ciba-Geigy Ag	Neue Aminoalkanphosphinsäuren und ihre Salze
IL126999A (en)	1996-07-24	2002-03-10	Warner Lambert Co	Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
EA200100143A1 (ru)	1998-07-15	2001-06-25	Хассан Йомаа	Фосфорорганические соединения и их применение
GB9906882D0 (en) *	1999-03-25	1999-05-19	Novartis Ag	Organic compounds
SE9904508D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
SE9904507D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
US7319095B2 (en)	1999-12-09	2008-01-15	Astrazeneca Ab	Use of GABAB receptor agonists
SE0102055D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Compounds
AR033779A1 (es)	2001-06-08	2004-01-07	Astrazeneca Ab	Compuestos utiles en la enfermedad de reflujo
US20050176680A1 (en)	2003-12-11	2005-08-11	Sepracor, Inc.	Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
SE0401653D0 (sv)	2004-06-24	2004-06-24	Astrazeneca Ab	New compounds
CA2632021A1 (en)	2005-12-23	2007-06-28	Astrazeneca Ab	Gaba-b receptor modulators
JP2009521428A (ja)	2005-12-23	2009-06-04	アストラゼネカ・アクチエボラーグ	胃腸疾患治療用のイミダゾール誘導体
DE102008056228A1 (de) *	2008-11-06	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) *	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (en)	2010-03-17	2011-09-22	INSERM (Institut National de la Santé et de la Recherche Médicale)	Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration
WO2012050907A2 (en)	2010-09-28	2012-04-19	The Regents Of The University Of California	Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3311475C1 (de) *	1983-03-29	1984-08-16	Siemens AG, 1000 Berlin und 8000 München	Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) *	1983-04-02	1984-10-04	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) *	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
GB8820266D0 (en) *	1988-08-26	1988-09-28	Smith Kline French Lab	Compounds

1989
- 1989-05-13 GB GB898911017A patent/GB8911017D0/en active Pending
1990
- 1990-05-07 IL IL94317A patent/IL94317A/xx not_active IP Right Cessation
- 1990-05-07 AU AU54809/90A patent/AU629335B2/en not_active Ceased
- 1990-05-08 DE DE69018514T patent/DE69018514T2/de not_active Expired - Fee Related
- 1990-05-08 EP EP90810346A patent/EP0399949B1/de not_active Expired - Lifetime
- 1990-05-08 AT AT90810346T patent/ATE121095T1/de not_active IP Right Cessation
- 1990-05-08 DK DK90810346.8T patent/DK0399949T3/da active
- 1990-05-08 ES ES90810346T patent/ES2070303T3/es not_active Expired - Lifetime
- 1990-05-09 MX MX2063990A patent/MX20639A/es unknown
- 1990-05-10 YU YU91790A patent/YU91790A/sh unknown
- 1990-05-10 SI SI9010917A patent/SI9010917B/sl unknown
- 1990-05-11 IE IE171690A patent/IE66165B1/en not_active IP Right Cessation
- 1990-05-11 DD DD90340576A patent/DD294265A5/de not_active IP Right Cessation
- 1990-05-11 FI FI902368A patent/FI94416C/fi not_active IP Right Cessation
- 1990-05-11 ZA ZA903611A patent/ZA903611B/xx unknown
- 1990-05-11 NO NO902109A patent/NO176761C/no not_active IP Right Cessation
- 1990-05-11 PT PT94014A patent/PT94014B/pt not_active IP Right Cessation
- 1990-05-11 KR KR1019900006687A patent/KR0159501B1/ko not_active Expired - Fee Related
- 1990-05-11 CA CA002016631A patent/CA2016631C/en not_active Expired - Lifetime
- 1990-05-11 HU HU903012A patent/HU206885B/hu not_active IP Right Cessation
- 1990-05-11 NZ NZ233647A patent/NZ233647A/en unknown
- 1990-05-14 JP JP2121395A patent/JP2930366B2/ja not_active Expired - Fee Related
1994
- 1994-03-18 HR HRP-917/90A patent/HRP940178A2/hr not_active Application Discontinuation
1995
- 1995-04-13 GR GR950400747T patent/GR3015770T3/el unknown

Also Published As

Publication number	Publication date
IL94317A (en)	1997-07-13
NO176761C (no)	1995-05-24
ES2070303T3 (es)	1995-06-01
IE66165B1 (en)	1995-12-13
DD294265A5 (de)	1991-09-26
CA2016631A1 (en)	1990-11-13
CA2016631C (en)	2000-08-29
IL94317A0 (en)	1991-03-10
FI94416B (fi)	1995-05-31
PT94014B (pt)	1996-12-31
MX20639A (es)	1993-12-01
JPH0395195A (ja)	1991-04-19
SI9010917B (sl)	1999-10-31
NO902109D0 (no)	1990-05-11
YU91790A (sh)	1992-07-20
HRP940178A2 (en)	1996-08-31
NO176761B (no)	1995-02-13
GR3015770T3 (en)	1995-07-31
PT94014A (pt)	1991-01-08
SI9010917A (en)	1997-06-30
FI94416C (fi)	1995-09-11
JP2930366B2 (ja)	1999-08-03
AU629335B2 (en)	1992-10-01
HUT53656A (en)	1990-11-28
NZ233647A (en)	1992-08-26
IE901716L (en)	1990-11-13
ATE121095T1 (de)	1995-04-15
KR0159501B1 (ko)	1999-01-15
EP0399949A1 (de)	1990-11-28
HU903012D0 (en)	1990-09-28
DE69018514D1 (de)	1995-05-18
KR900018124A (ko)	1990-12-20
DE69018514T2 (de)	1995-09-21
NO902109L (no)	1990-11-14
AU5480990A (en)	1990-11-15
FI902368A0 (fi)	1990-05-11
HU206885B (en)	1993-01-28
EP0399949B1 (de)	1995-04-12
GB8911017D0 (en)	1989-06-28
DK0399949T3 (da)	1995-07-03

Publication	Publication Date	Title
GB8911017D0 (en)	1989-06-28	Substituted aminoalkylphosphinic acids
EP0747383A3 (de)	1996-12-18	Clavulansäure Polyaminsalze
TWI255807B (en)	2006-06-01	Therapeutic agents
IE820211L (en)	1982-08-02	Process for preparing 2-penem compounds
DE68917023D1 (de)	1994-09-01	3-Pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-en-2-carbonsäureverbindungen.
DE3870801D1 (de)	1992-06-11	Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.
WO1987004926A3 (en)	1988-05-19	Method of modifying the lipid structure of cell membranes and pharmaceutical compositions for use therein
TW355705B (en)	1999-04-11	Substituted benzyloxycarbonylguanidines, process for their preparation, their medical use and pharmaceutical composition containing them
PL285752A1 (en)	1991-03-11	Method for manufacturing new indenoindols and a pharmaceutical composition
AU655869B2 (en)	1995-01-12	An amphoteric tricyclic compound
HUT46214A (en)	1988-10-28	Process for producing medical preparation suitable for treatment of peptic ulcer
DE3782548D1 (de)	1992-12-17	Ergolin-ester, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammenstellungen.
IE800049L (en)	1980-07-13	Hexahydro-1, 4-oxazepines
AU557880B2 (en)	1987-01-15	Method for modulating the immune response with dibenzocycloheptenylidenes
WO1987003590A1 (fr)	1987-06-18	Medicament pour le traitement des maladies du foie
DK634686D0 (da)	1986-12-30	Dioxahexensyrer, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse
ES8405372A1 (es)	1984-06-01	Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido.
ATE101609T1 (de)	1994-03-15	Amino-substituierte verbrueckte azabicyclische chinoloncarbonsaeure und ester.
ES2000782A6 (es)	1988-03-16	Procedimiento para la preparacion de derivados de dihidroquinolina.
ES2004255A6 (es)	1988-12-16	Procedimiento de preparar compuestos del tipo de las piracinas y analogos.
ATE97902T1 (de)	1993-12-15	Cephemverbindungen und verfahren zu ihrer herstellung.