ATE122245T1 - Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben. - Google Patents

Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben.

Info

Publication number
ATE122245T1
ATE122245T1 AT92900178T AT92900178T ATE122245T1 AT E122245 T1 ATE122245 T1 AT E122245T1 AT 92900178 T AT92900178 T AT 92900178T AT 92900178 T AT92900178 T AT 92900178T AT E122245 T1 ATE122245 T1 AT E122245T1
Authority
AT
Austria
Prior art keywords
electrode
drug
hydration
medications
reservoirs
Prior art date
Application number
AT92900178T
Other languages
English (en)
Inventor
Ronald P Haak
J Richard Gyory
Felix Theeuwes
Robert M Myers
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24423053&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE122245(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE122245T1 publication Critical patent/ATE122245T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • External Artificial Organs (AREA)
AT92900178T 1990-10-29 1991-10-25 Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben. ATE122245T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60529090A 1990-10-29 1990-10-29

Publications (1)

Publication Number Publication Date
ATE122245T1 true ATE122245T1 (de) 1995-05-15

Family

ID=24423053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900178T ATE122245T1 (de) 1990-10-29 1991-10-25 Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben.

Country Status (18)

Country Link
US (1) US5385543A (de)
EP (1) EP0555375B2 (de)
JP (1) JP3149950B2 (de)
KR (1) KR930702043A (de)
AT (1) ATE122245T1 (de)
AU (2) AU652202B2 (de)
CA (1) CA2090313A1 (de)
DE (1) DE69109690T3 (de)
DK (1) DK0555375T3 (de)
ES (1) ES2072134T3 (de)
FI (1) FI931915L (de)
IE (1) IE68247B1 (de)
MX (1) MX9101782A (de)
NO (1) NO931207D0 (de)
NZ (1) NZ240357A (de)
PT (1) PT99344A (de)
WO (1) WO1992007618A1 (de)
ZA (1) ZA918528B (de)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374241A (en) * 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
JP2818075B2 (ja) * 1992-05-27 1998-10-30 久光製薬株式会社 イオントフォレーシス用インタフェース
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
FI944321L (fi) * 1992-11-05 1994-11-16 Becton Dickinson Co Käyttäjäaktivoitu iontoforeettinen laite ja menetelmä sen käyttämiseksi
DE69532503T2 (de) * 1994-06-17 2004-11-04 Hisamitsu Pharmaceutical Co., Inc., Tosu Elektrode für iontophorese und vorrichtung dafür
US5736580A (en) * 1994-11-14 1998-04-07 Alza Croporation Composition, device, and method for electrotransport agent delivery
US5961483A (en) * 1996-06-19 1999-10-05 Sage; Burton H. Iontophoretic delivery of cell adhesion inhibitors
CN1095681C (zh) * 1996-06-20 2002-12-11 久光制药株式会社 一种用于离子电渗疗法的装置结构
US5941843A (en) * 1996-07-12 1999-08-24 Empi, Inc. Iontophoresis electrode
US5857993A (en) * 1996-07-12 1999-01-12 Empi, Inc. Process of making an iontophoresis electrode
US5871461A (en) * 1996-07-12 1999-02-16 Empi, Inc. Method of making an iontophoresis electrode
US5713846A (en) 1996-09-27 1998-02-03 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US5738647A (en) 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US5693024A (en) 1996-09-27 1997-12-02 Becton Dickinson And Company Iontophoretic drug delivery system, including method for determining hydration of patch
US5797867A (en) 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
AU4656097A (en) * 1996-09-30 1998-04-24 Becton Dickinson & Company Designs to prevent transport of drug solution for use in assembly or packaging of an iontophoretic patch
FR2755372B1 (fr) * 1996-11-07 1998-12-24 Elf Aquitaine Dispositif d'ionophorese comportant au moins un ensemble electrode a membrane, pour l'administration transcutanee de principes actifs a un sujet
US6246904B1 (en) * 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
KR100453132B1 (ko) 1996-12-20 2004-10-15 앨자 코포레이션 경피 약제 플럭스를 향상시키기 위한 장치 및 방법
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US5846217A (en) * 1997-07-29 1998-12-08 Iomed, Inc. Iontophoretic bioelectrode and method of using same
EP1030560B1 (de) 1997-10-09 2007-09-26 Emory University Verfahren und vorrichtung zur transdermalen verabreichung von lithium
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CN1161164C (zh) * 1997-12-11 2004-08-11 阿尔扎有限公司 用于通过体表导入或提取质剂的装置
DK1037687T3 (da) 1997-12-11 2009-01-26 Alza Corp Anordning til at forbedre et middels transdermale strömning
PT1037686E (pt) * 1997-12-11 2005-10-31 Alza Corp Aparelho para potenciar o fluxo de agente transdermico
EP1911488A3 (de) 1997-12-11 2008-12-03 Alza Corporation Vorrichtung zur Verstärkung des Flusses transdermaler Mittel
US6374136B1 (en) 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
EP0962233A1 (de) * 1998-06-03 1999-12-08 Sport-Elec S.A. Elektrodeneinheit zur Elektrotherapie
EP1115454B1 (de) * 1998-08-31 2006-10-25 Travanti Pharma Inc Gesteuerte medikamentdosierungsvorrichtung
US6275728B1 (en) * 1998-12-22 2001-08-14 Alza Corporation Thin polymer film drug reservoirs
US6198966B1 (en) 1999-02-26 2001-03-06 Medtronic, Inc. Recirculating implantable drug delivery system
WO2000062856A1 (en) * 1999-04-16 2000-10-26 Johnson & Johnson Consumer Companies, Inc. Drug delivery device comprising a dual chamber reservoir
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6629968B1 (en) 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
US7083580B2 (en) * 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7520875B2 (en) * 2001-04-06 2009-04-21 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
US6745071B1 (en) * 2003-02-21 2004-06-01 Birch Point Medical, Inc. Iontophoretic drug delivery system
EP1680178A4 (de) * 2003-10-31 2008-01-02 Alza Corp System und verfahren für die transdermale abgabe einer vakzine
WO2005069758A2 (en) * 2004-01-09 2005-08-04 Alza Corporation Frequency assisted transdermal agent delivery method and system
US20050228335A1 (en) 2004-04-07 2005-10-13 Reddy Vilambi N Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems
US20050228336A1 (en) 2004-04-07 2005-10-13 Preston Keusch Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
US20060135906A1 (en) * 2004-11-16 2006-06-22 Akihiko Matsumura Iontophoretic device and method for administering immune response-enhancing agents and compositions
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
EP1905433A1 (de) * 2005-07-15 2008-04-02 Transcu Ltd. Perkutanes absorptionsplfaster mit hinweis auf die applikationsposition und iontophoretische vorrichtung
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
WO2007023907A1 (ja) * 2005-08-24 2007-03-01 Transcu Ltd. 冷凍型イオントフォレーシス用電極構造体
JPWO2007026672A1 (ja) * 2005-08-29 2009-03-05 Tti・エルビュー株式会社 イオントフォレーシス用汎用性電解液組成物
US20100030128A1 (en) * 2005-09-06 2010-02-04 Kazuma Mitsuguchi Iontophoresis device
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
KR20080047600A (ko) * 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
BRPI0616166A2 (pt) * 2005-09-16 2011-06-07 Tti Ellebeau Inc dispositivo de iontoforese do tipo de cateter
WO2007037324A1 (ja) * 2005-09-28 2007-04-05 Transcu Ltd. 乾燥型イオントフォレーシス用電極構造体
EP1928542A1 (de) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Verfahren und system zum nachweis von fehlfunktionen in einer iontophorese-vorrichtung, die wirkstoffe an biologische schnittstellen abgibt
JPWO2007037476A1 (ja) * 2005-09-30 2009-04-16 Tti・エルビュー株式会社 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
US20090299265A1 (en) * 2005-09-30 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
WO2007041476A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Indications for local transport of anaesthetic agents by electrotransport devices
KR20080080087A (ko) * 2005-09-30 2008-09-02 티티아이 엘뷰 가부시키가이샤 신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
WO2007041386A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Pulsatile delivery of gonadotropin-releasing hormone from a pre-loaded integrated electrotransport patch
JP2009509657A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2007038555A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
WO2007041475A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Iontophoresis drug delivery formulation providing acceptable sensation and dermal anesthesia
US20070093787A1 (en) * 2005-09-30 2007-04-26 Transcutaneous Technologies Inc. Iontophoresis device to deliver multiple active agents to biological interfaces
JP2009509677A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
US20070093743A1 (en) * 2005-09-30 2007-04-26 Vyteris, Inc. Iontophoresis Drug Delivery Device Providing Acceptable Depth and Duration of Dermal Anesthesia
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
EP1965856A2 (de) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. Iontophoretische systeme, vorrichtungen und verfahren zur abgabe von wirkstoffen an eine biologische schnittstelle
WO2007123707A1 (en) * 2006-03-30 2007-11-01 Tti Ellebeau, Inc. Controlled release membrane and methods of use
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
WO2008030497A2 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
TW200838576A (en) 2006-12-01 2008-10-01 Transcu Ltd Systems, devices and methods for powering and/or controlling transdermal delivery devices
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
NZ582049A (en) * 2007-05-18 2012-12-21 Tti Ellebeau Inc Transdermal delivery devices assuring an improved release of an active principle through a biological interface
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
WO2009003173A1 (en) 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodymanic therapy
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
CN102159205A (zh) * 2008-06-25 2011-08-17 Fe3医学有限公司 用于经皮递送治疗有效量的铁的贴片和方法
JP2012501801A (ja) * 2008-09-10 2012-01-26 トランスキュー リミテッド ヒドロキシプロピルセルロース(hpc)をベースにした粘性液体を多孔質基材に薬剤投与する装置および方法、例えば連続ウェブをベースにしたプロセス
US8348922B2 (en) * 2009-02-12 2013-01-08 Incube Labs, Llc Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
KR101674904B1 (ko) 2009-02-26 2016-11-10 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 중재형 약물전달 시스템과 그 방법
US8821945B2 (en) * 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
EP2440694A4 (de) * 2009-06-09 2012-12-19 Tti Ellebeau Inc Langlebige elektrode von hoher kapazität und herstellungsverfahren dafür
WO2010151845A2 (en) * 2009-06-26 2010-12-29 Incube Labs, Llc Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use
US8903485B2 (en) * 2009-08-06 2014-12-02 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
JP5864429B2 (ja) 2009-11-09 2016-02-17 スポットライト テクノロジー パートナーズ エルエルシーSpotlight Technology Partners Llc 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
WO2011100376A2 (en) 2010-02-10 2011-08-18 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
AU2012230701B2 (en) 2011-03-24 2016-09-29 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
WO2012154704A2 (en) 2011-05-06 2012-11-15 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
FI125075B (fi) * 2012-08-13 2015-05-29 Novagent Oy Vaikuttavan aineen iontoforeettinen annostelujärjestelmä

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE399044A (de) * 1933-09-09
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US3982529A (en) * 1974-06-25 1976-09-28 Sato Takuya R Bioelectrodes
US4166457A (en) * 1976-08-16 1979-09-04 University Of Utah Research Institute Fluid self-sealing bioelectrode
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
JPS56501274A (de) * 1979-10-10 1981-09-10
US4367745A (en) 1980-05-27 1983-01-11 Minnesota Mining And Manufacturing Company Conformable electrically conductive compositions
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4820263A (en) * 1981-03-06 1989-04-11 Medtronic, Inc. Apparatus and method for iontophoretic drug delivery
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4419092A (en) * 1981-11-06 1983-12-06 Motion Control, Inc. Iontophoretic electrode structure
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
FR2562800A1 (fr) * 1984-04-11 1985-10-18 Fournier Laboratoires Dispositif pour l'administration percutanee de medicaments
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
JPS63102768A (ja) * 1986-10-20 1988-05-07 山之内製薬株式会社 イオントフオレ−シス用の新規プラスタ−構造体
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US4940456A (en) * 1987-02-10 1990-07-10 Dan Sibalis Electrolytic transdermal delivery of proteins
WO1990008571A1 (en) * 1989-02-06 1990-08-09 Kabushiki Kaisha Advance Interface for iontophoresis
US5234992A (en) * 1989-02-09 1993-08-10 Alza Corporation Electrotransport adhesive
US5087242A (en) * 1989-07-21 1992-02-11 Iomed, Inc. Hydratable bioelectrode
US5087241A (en) * 1990-07-24 1992-02-11 Empi, Inc. Iontophoresis electrode with reservoir and injection site
US5158537A (en) * 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
US5156591A (en) * 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same

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EP0555375B2 (de) 1999-02-03
IE68247B1 (en) 1996-06-12
FI931915A7 (fi) 1993-04-28
FI931915A0 (fi) 1993-04-28
AU652202B2 (en) 1994-08-18
EP0555375B1 (de) 1995-05-10
DE69109690T3 (de) 1999-06-02
WO1992007618A1 (en) 1992-05-14
NO931207D0 (no) 1993-03-31
DE69109690T2 (de) 1995-09-07
ES2072134T3 (es) 1995-07-01
FI931915L (fi) 1993-04-28
JP3149950B2 (ja) 2001-03-26
DE69109690D1 (de) 1995-06-14
CA2090313A1 (en) 1992-04-30
US5385543A (en) 1995-01-31
AU6747194A (en) 1994-09-15
IE913737A1 (en) 1992-05-22
NZ240357A (en) 1993-04-28
JPH06502097A (ja) 1994-03-10
ZA918528B (en) 1992-08-26
AU9034391A (en) 1992-05-26
MX9101782A (es) 1992-06-05
EP0555375A1 (de) 1993-08-18
DK0555375T3 (da) 1995-07-10
KR930702043A (ko) 1993-09-08
AU658789B2 (en) 1995-04-27
PT99344A (pt) 1993-12-31

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