ATE122245T1 - Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben. - Google Patents

Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben.

Info

Publication number
ATE122245T1
ATE122245T1 AT92900178T AT92900178T ATE122245T1 AT E122245 T1 ATE122245 T1 AT E122245T1 AT 92900178 T AT92900178 T AT 92900178T AT 92900178 T AT92900178 T AT 92900178T AT E122245 T1 ATE122245 T1 AT E122245T1
Authority
AT
Austria
Prior art keywords
electrode
drug
hydration
medications
reservoirs
Prior art date
Application number
AT92900178T
Other languages
English (en)
Inventor
Ronald P Haak
J Richard Gyory
Felix Theeuwes
Robert M Myers
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24423053&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE122245(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE122245T1 publication Critical patent/ATE122245T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Water Treatment By Electricity Or Magnetism (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicinal Preparation (AREA)
AT92900178T 1990-10-29 1991-10-25 Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben. ATE122245T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60529090A 1990-10-29 1990-10-29

Publications (1)

Publication Number Publication Date
ATE122245T1 true ATE122245T1 (de) 1995-05-15

Family

ID=24423053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900178T ATE122245T1 (de) 1990-10-29 1991-10-25 Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben.

Country Status (18)

Country Link
US (1) US5385543A (de)
EP (1) EP0555375B2 (de)
JP (1) JP3149950B2 (de)
KR (1) KR930702043A (de)
AT (1) ATE122245T1 (de)
AU (2) AU652202B2 (de)
CA (1) CA2090313A1 (de)
DE (1) DE69109690T3 (de)
DK (1) DK0555375T3 (de)
ES (1) ES2072134T3 (de)
FI (1) FI931915L (de)
IE (1) IE68247B1 (de)
MX (1) MX9101782A (de)
NO (1) NO931207D0 (de)
NZ (1) NZ240357A (de)
PT (1) PT99344A (de)
WO (1) WO1992007618A1 (de)
ZA (1) ZA918528B (de)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374241A (en) * 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
JP2818075B2 (ja) * 1992-05-27 1998-10-30 久光製薬株式会社 イオントフォレーシス用インタフェース
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
JP2542792B2 (ja) * 1992-11-05 1996-10-09 ベクトン・ディッキンソン・アンド・カンパニー ユ―ザ作動型のイオン導入式装置
US6006130A (en) * 1994-06-17 1999-12-21 Hisamitsu Pharmaceutical Co. Iontophoresis electrode and iontophoresis device using the electrode
US5736580A (en) * 1994-11-14 1998-04-07 Alza Croporation Composition, device, and method for electrotransport agent delivery
US5961483A (en) * 1996-06-19 1999-10-05 Sage; Burton H. Iontophoretic delivery of cell adhesion inhibitors
CA2208336A1 (en) * 1996-06-20 1997-12-20 Hisamitsu Pharmaceuticals Co., Inc. A device structure for iontophoresis
US5857993A (en) * 1996-07-12 1999-01-12 Empi, Inc. Process of making an iontophoresis electrode
US5941843A (en) * 1996-07-12 1999-08-24 Empi, Inc. Iontophoresis electrode
US5871461A (en) * 1996-07-12 1999-02-16 Empi, Inc. Method of making an iontophoresis electrode
US5738647A (en) 1996-09-27 1998-04-14 Becton Dickinson And Company User activated iontophoretic device and method for activating same
US5713846A (en) 1996-09-27 1998-02-03 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US5693024A (en) 1996-09-27 1997-12-02 Becton Dickinson And Company Iontophoretic drug delivery system, including method for determining hydration of patch
US5797867A (en) 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
WO1998014236A1 (en) * 1996-09-30 1998-04-09 Becton Dickinson And Company Designs to prevent transport of drug solution for use in assembly or packaging of an iontophoretic patch
FR2755372B1 (fr) * 1996-11-07 1998-12-24 Elf Aquitaine Dispositif d'ionophorese comportant au moins un ensemble electrode a membrane, pour l'administration transcutanee de principes actifs a un sujet
US6246904B1 (en) * 1996-12-17 2001-06-12 Alza Corporation Electrotransport drug delivery reservoirs containing inert fillers
ATE234649T1 (de) 1996-12-20 2003-04-15 Alza Corp Vorrichtung und verfahren zur erhöhung des transdermalen wirkstoffeflusses
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US5846217A (en) * 1997-07-29 1998-12-08 Iomed, Inc. Iontophoretic bioelectrode and method of using same
DE69838485T2 (de) 1997-10-09 2008-06-26 Emory University Verfahren und vorrichtung zur transdermalen verabreichung von lithium
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
AU739616B2 (en) * 1997-12-11 2001-10-18 Alza Corporation Device for enhancing transdermal agent flux
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
EP1037686B1 (de) * 1997-12-11 2005-08-17 Alza Corporation Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP1911488A3 (de) 1997-12-11 2008-12-03 Alza Corporation Vorrichtung zur Verstärkung des Flusses transdermaler Mittel
US6374136B1 (en) * 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
EP0962233A1 (de) * 1998-06-03 1999-12-08 Sport-Elec S.A. Elektrodeneinheit zur Elektrotherapie
ATE343411T1 (de) * 1998-08-31 2006-11-15 Travanti Pharma Inc Gesteuerte medikamentdosierungsvorrichtung
US6275728B1 (en) * 1998-12-22 2001-08-14 Alza Corporation Thin polymer film drug reservoirs
US6198966B1 (en) 1999-02-26 2001-03-06 Medtronic, Inc. Recirculating implantable drug delivery system
JP2002541934A (ja) * 1999-04-16 2002-12-10 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 二重チャンバー式貯蔵器を備えている薬物供給装置
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
HK1048604B (en) 1999-12-10 2006-05-04 Alza Corporation Device and method for enhancing microprotrusion skin piercing
US7404815B2 (en) 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6629968B1 (en) 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
US7520875B2 (en) * 2001-04-06 2009-04-21 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7083580B2 (en) * 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
US6745071B1 (en) 2003-02-21 2004-06-01 Birch Point Medical, Inc. Iontophoretic drug delivery system
US20050123565A1 (en) * 2003-10-31 2005-06-09 Janardhanan Subramony System and method for transdermal vaccine delivery
BRPI0417757A (pt) * 2004-01-09 2007-04-10 Alza Corp método e sistema de liberação de agente transdérmico assistida por freqüência
US20050228335A1 (en) 2004-04-07 2005-10-13 Reddy Vilambi N Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems
US20050228336A1 (en) 2004-04-07 2005-10-13 Preston Keusch Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
TW200640526A (en) * 2005-02-24 2006-12-01 Alza Corp Transdermal electrotransport drug delivery systems with reduced abuse potential
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
JPWO2007010900A1 (ja) * 2005-07-15 2009-01-29 Ｔｔｉ・エルビュー株式会社 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
WO2007023907A1 (ja) * 2005-08-24 2007-03-01 Transcu Ltd. 冷凍型イオントフォレーシス用電極構造体
WO2007026672A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. イオントフォレーシス用汎用性電解液組成物
WO2007029611A1 (ja) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
KR20080047600A (ko) * 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
RU2008114830A (ru) * 2005-09-16 2009-10-27 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Устройство ионтофореза катетерного типа
WO2007037324A1 (ja) * 2005-09-28 2007-04-05 Transcu Ltd. 乾燥型イオントフォレーシス用電極構造体
WO2007041314A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods employing novel pharmaceutical vehicles
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
WO2007041475A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Iontophoresis drug delivery formulation providing acceptable sensation and dermal anesthesia
US20070093743A1 (en) * 2005-09-30 2007-04-26 Vyteris, Inc. Iontophoresis Drug Delivery Device Providing Acceptable Depth and Duration of Dermal Anesthesia
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
AU2006299520A1 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoresis device to deliver multiple active agents to biological interfaces
JP2009509677A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
WO2007037476A1 (ja) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. 睡眠導入剤と興奮剤の投与量および投与時期を制御するイオントフォレーシス装置
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
JP2009509682A (ja) * 2005-09-30 2009-03-12 バイテリス，インコーポレイテッド 予め充填された結合電気搬送パッチからの性腺刺激ホルモン放出ホルモンのパルス状搬送
JP4902543B2 (ja) * 2005-09-30 2012-03-21 Ｔｔｉ・エルビュー株式会社 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
US7574256B2 (en) 2005-09-30 2009-08-11 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
US20070078434A1 (en) * 2005-09-30 2007-04-05 Vyteris, Inc. Indications For Local Transport of Anaesthetic Agents By Electrotransport Devices
EP1928542A1 (de) * 2005-09-30 2008-06-11 Tti Ellebeau, Inc. Verfahren und system zum nachweis von fehlfunktionen in einer iontophorese-vorrichtung, die wirkstoffe an biologische schnittstellen abgibt
US20070083185A1 (en) * 2005-09-30 2007-04-12 Darrick Carter Iontophoretic device and method of delivery of active agents to biological interface
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
WO2007079190A2 (en) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Device and method for enhancing immune response by electrical stimulation
JP2009522011A (ja) * 2005-12-30 2009-06-11 Ｔｔｉ・エルビュー株式会社 活性物質を生体界面に送達するイオントフォレーシスシステム、装置及び方法
WO2007123707A1 (en) * 2006-03-30 2007-11-01 Tti Ellebeau, Inc. Controlled release membrane and methods of use
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
CA2661879A1 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
EP2061551A2 (de) 2006-12-01 2009-05-27 TTI ellebeau, Inc. Systeme, vorrichtungen und verfahren zum antrieb oder zur steuerung von geräten, z. b. geräten zur transdermalen verabreichung
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
MX2009012273A (es) * 2007-05-18 2010-04-09 Tti Ellebeau Inc Dispositivos de suministro transd?rmico que aseguran la liberaci?n mejorada de un principio activo a trav?s de una interfaz biol?gica.
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
ES2454974T3 (es) 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
AU2009262967C1 (en) 2008-06-25 2015-12-24 Fe3 Medical, Inc Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
CA2736495A1 (en) * 2008-09-10 2010-03-18 Gregory A. Smith Apparatus and method to dispense hpc-based viscous liquids into porous substrates, e.g., continuous web-based process
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US8190252B2 (en) * 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US9008765B2 (en) 2009-02-12 2015-04-14 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
US8348922B2 (en) * 2009-02-12 2013-01-08 Incube Labs, Llc Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
EP2401027B1 (de) 2009-02-26 2017-11-01 The University of North Carolina At Chapel Hill Interventionelles arzneimittelabgabesystem
US8821945B2 (en) 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
EP2440694A4 (de) * 2009-06-09 2012-12-19 Tti Ellebeau Inc Langlebige elektrode von hoher kapazität und herstellungsverfahren dafür
WO2010151845A2 (en) * 2009-06-26 2010-12-29 Incube Labs, Llc Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use
WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
JP5864429B2 (ja) 2009-11-09 2016-02-17 スポットライト テクノロジー パートナーズ エルエルシーＳｐｏｔｌｉｇｈｔ Ｔｅｃｈｎｏｌｏｇｙ Ｐａｒｔｎｅｒｓ Ｌｌｃ 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット
JP2013509963A (ja) 2009-11-09 2013-03-21 スポットライト テクノロジー パートナーズ エルエルシー 断片化ヒドロゲル
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
WO2011100376A2 (en) 2010-02-10 2011-08-18 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
AU2012230701B2 (en) 2011-03-24 2016-09-29 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
FI125075B (fi) * 2012-08-13 2015-05-29 Novagent Oy Vaikuttavan aineen iontoforeettinen annostelujärjestelmä

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE399044A (de) * 1933-09-09
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US3982529A (en) * 1974-06-25 1976-09-28 Sato Takuya R Bioelectrodes
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4166457A (en) * 1976-08-16 1979-09-04 University Of Utah Research Institute Fluid self-sealing bioelectrode
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
JPS56501274A (de) * 1979-10-10 1981-09-10
US4367745A (en) 1980-05-27 1983-01-11 Minnesota Mining And Manufacturing Company Conformable electrically conductive compositions
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4820263A (en) * 1981-03-06 1989-04-11 Medtronic, Inc. Apparatus and method for iontophoretic drug delivery
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4419092A (en) * 1981-11-06 1983-12-06 Motion Control, Inc. Iontophoretic electrode structure
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
FR2562800A1 (fr) * 1984-04-11 1985-10-18 Fournier Laboratoires Dispositif pour l'administration percutanee de medicaments
US4744787A (en) 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
JPS63102768A (ja) * 1986-10-20 1988-05-07 山之内製薬株式会社 イオントフオレ−シス用の新規プラスタ−構造体
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US4940456A (en) * 1987-02-10 1990-07-10 Dan Sibalis Electrolytic transdermal delivery of proteins
WO1990008571A1 (en) * 1989-02-06 1990-08-09 Kabushiki Kaisha Advance Interface for iontophoresis
US5234992A (en) * 1989-02-09 1993-08-10 Alza Corporation Electrotransport adhesive
US5087242A (en) * 1989-07-21 1992-02-11 Iomed, Inc. Hydratable bioelectrode
US5087241A (en) * 1990-07-24 1992-02-11 Empi, Inc. Iontophoresis electrode with reservoir and injection site
US5158537A (en) * 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
US5156591A (en) * 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same

Also Published As

Publication number Publication date
ES2072134T3 (es) 1995-07-01
JPH06502097A (ja) 1994-03-10
AU6747194A (en) 1994-09-15
NO931207D0 (no) 1993-03-31
MX9101782A (es) 1992-06-05
AU652202B2 (en) 1994-08-18
EP0555375B1 (de) 1995-05-10
ZA918528B (en) 1992-08-26
FI931915A0 (fi) 1993-04-28
FI931915A7 (fi) 1993-04-28
EP0555375B2 (de) 1999-02-03
FI931915L (fi) 1993-04-28
AU9034391A (en) 1992-05-26
NZ240357A (en) 1993-04-28
EP0555375A1 (de) 1993-08-18
DE69109690D1 (de) 1995-06-14
DK0555375T3 (da) 1995-07-10
DE69109690T3 (de) 1999-06-02
US5385543A (en) 1995-01-31
DE69109690T2 (de) 1995-09-07
JP3149950B2 (ja) 2001-03-26
CA2090313A1 (en) 1992-04-30
AU658789B2 (en) 1995-04-27
IE913737A1 (en) 1992-05-22
KR930702043A (ko) 1993-09-08
IE68247B1 (en) 1996-06-12
PT99344A (pt) 1993-12-31
WO1992007618A1 (en) 1992-05-14

Similar Documents

Publication Publication Date Title
ATE122245T1 (de) Elektrode zur iontophoretischen verabreichung von medikamenten und verfahren zur hydratation derselben.
ATE155347T1 (de) Gerät zur iontophoretischen verabreichung von medikamenten
ATE167404T1 (de) Vorrichtung zur iontophoretischen verabreichung von medikamenten und verfahren für ihre herstellung
US5087240A (en) Transdermal drug patch with conductive fibers
US4856188A (en) Method for making disposable and/or replenishable transdermal drug applicators
US4865582A (en) Disposable transdermal drug applicators
US6731977B2 (en) Iontophoretic electrode with improved current distribution
AR241261A1 (es) Mejoras en un aplicador para la administracion sub-cutanea no invasiva de medicamentos.
ES2065181T3 (es) Dispositivo de suministro iontoforetico y procedimiento para su fabricacion.
US5651768A (en) Transdermal drug applicator and electrodes therefor
CA1287665C (en) Transdermal drug applicator and electrodes therefor
PT97140A (pt) Dispositivo para a administracao de substancias activas farmaceuticas por electroforese ionica
ATE114486T1 (de) Verfahren und vorrichtung zur iontophoretischen abgabe von medikamenten.
KR960703025A (ko) 이온삼투요법용 장치(iontophoresis device)
JP4332429B2 (ja) 一体成型されたリザーバーハウジングを有する電気輸送装置
DE50008866D1 (de) Verfahren und vorrichtung zum elektrolytischen behandeln von elektrisch gegeneinander isolierten, elektrisch leitfähigen strukturen auf oberflächen von elektrisch isolierendem folienmaterial sowie anwendungen des verfahrens
EP1916014A1 (de) Behältergehäuse mit darin integriertem leitfähigem Bereich
AU2007203024B2 (en) Reservoir housing having a conductive region integrally formed therein

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee