ATE123520T1 - Kex2-endoprotease und verfahren zu ihrer herstellung. - Google Patents

Kex2-endoprotease und verfahren zu ihrer herstellung.

Info

Publication number
ATE123520T1
ATE123520T1 AT89301051T AT89301051T ATE123520T1 AT E123520 T1 ATE123520 T1 AT E123520T1 AT 89301051 T AT89301051 T AT 89301051T AT 89301051 T AT89301051 T AT 89301051T AT E123520 T1 ATE123520 T1 AT E123520T1
Authority
AT
Austria
Prior art keywords
production
kex2 endoprotease
dna
terminal
mentioned
Prior art date
Application number
AT89301051T
Other languages
English (en)
Inventor
Takehiro Oshima
Kensaku Mizuno
Original Assignee
Suntory Ltd
Matsuo Hisayuki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12067048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE123520(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Suntory Ltd, Matsuo Hisayuki filed Critical Suntory Ltd
Application granted granted Critical
Publication of ATE123520T1 publication Critical patent/ATE123520T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Mushroom Cultivation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Details Of Garments (AREA)
  • Edible Seaweed (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
AT89301051T 1988-02-03 1989-02-03 Kex2-endoprotease und verfahren zu ihrer herstellung. ATE123520T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63021866A JP2643968B2 (ja) 1988-02-03 1988-02-03 Ｋｅｘ２エンドプロテアーゼ及びその製造方法

Publications (1)

Publication Number Publication Date
ATE123520T1 true ATE123520T1 (de) 1995-06-15

Family

ID=12067048

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89301051T ATE123520T1 (de) 1988-02-03 1989-02-03 Kex2-endoprotease und verfahren zu ihrer herstellung.

Country Status (7)

Country Link
US (1) US5162220A (de)
EP (1) EP0327377B1 (de)
JP (1) JP2643968B2 (de)
AT (1) ATE123520T1 (de)
CA (1) CA1335966C (de)
DE (1) DE68922917T2 (de)
ES (1) ES2072893T3 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645174B1 (fr) * 1989-03-31 1994-01-07 Transgene Sa Souches de levure ameliorees pour la production de proteines heterologues matures en particulier d'hirudine et procede de preparation d'hirudine correspondant
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
JP3270462B2 (ja) * 1989-12-29 2002-04-02 ザイモジェネティクス，インコーポレイティド ハイブリッドプロテインｃ
US5541062A (en) * 1990-02-23 1996-07-30 Arch Development Corporation Methods and compositions for preparing protein processing enzymes
JPH07108232B2 (ja) * 1990-10-09 1995-11-22 エム・ディ・リサーチ株式会社 ペプチド又は蛋白質の製造方法
EP0785273A1 (de) * 1990-11-26 1997-07-23 Genetics Institute, Inc. Gepaarte basische Aminosäuren konvertierendes Enzym und dafür kodierende DNA Sequenz
GB9117910D0 (en) * 1991-08-20 1991-10-09 Nat Res Dev Oligonucleotides and their use in an assay
US5618673A (en) * 1991-08-20 1997-04-08 British Technology Group Limited Oligonucleotides and their use in an assay for encephalopathies
US6348327B1 (en) 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
ATE204606T1 (de) * 1991-12-06 2001-09-15 Genentech Inc Prohormon konvertase transformierte zellen.
DK0548012T3 (da) * 1991-12-16 1998-04-14 Ciba Geigy Ag Endoplasmatisk reticulum-placeret rekombinant dibasisk endoprotease samt dens anvendelse
US5846802A (en) * 1992-04-15 1998-12-08 Buxton; Frank Fungal Protease
US5413914A (en) * 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US5866351A (en) * 1993-07-07 1999-02-02 University Technology Corporation CD4+ T-lymphocyte proteases and genes encoding said proteases
US5981259A (en) * 1993-07-07 1999-11-09 University Technology Corporation CD4+ T-lymphocyte protease genes and inhibitors thereof
US5691183A (en) * 1993-07-07 1997-11-25 University Technology Corporation CD4+ T-lymphoctye proteases and genes encoding said proteases
CA2198968C (en) * 1996-03-04 2010-02-09 Toyofumi Masuda Process for production of secretory kex2 derivatives
GB9606261D0 (en) * 1996-03-25 1996-05-29 Johnson & Johnson Clin Diag Prenatal screening for fetal abnormalities
CA2258291A1 (en) * 1996-06-28 1998-01-08 Novo Nordisk A/S A recombinant enzyme with mutanase activity
SK782002A3 (en) 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
CN1300818A (zh) * 1999-12-21 2001-06-27 复旦大学 一种新的多肽－蛋白内切酶Clp12和编码这种多肽的多核苷酸
IT1319659B1 (it) * 2000-11-16 2003-10-23 Norpharma S P A Endoproteasi solubili per il processamento in vitro di proteinericombinanti.
US7348004B2 (en) 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
AU2004238263A1 (en) * 2003-05-06 2004-11-25 Syntonix Pharmaceuticals, Inc. Inhibition of drug binding to serum albumin
ES2333598T5 (es) 2003-05-06 2013-09-04 Biogen Idec Hemophilia Inc Proteinas quimericas del factor de coagulacion fc para tratar la hemofilia.
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
US10180572B2 (en) 2010-02-28 2019-01-15 Microsoft Technology Licensing, Llc AR glasses with event and user action control of external applications
CA2903739A1 (en) 2013-03-06 2014-09-12 Glaxosmithkline Llc Host cells and methods of use
TWI828269B (zh) 2013-03-15 2024-01-01 美商百歐維拉提夫治療公司 因子ix多肽調配物
CN106337042B (zh) * 2015-07-16 2019-08-09 上海雅心生物技术有限公司 双碱基酶kex2变体及其高效表达方法

Also Published As

Publication number Publication date
ES2072893T3 (es) 1995-08-01
EP0327377A2 (de) 1989-08-09
JPH01199578A (ja) 1989-08-10
EP0327377A3 (en) 1990-05-09
CA1335966C (en) 1995-06-20
EP0327377B1 (de) 1995-06-07
US5162220A (en) 1992-11-10
DE68922917T2 (de) 1995-10-26
JP2643968B2 (ja) 1997-08-25
DE68922917D1 (de) 1995-07-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time