ATE124996T1 - Alpha-glycosylhesperidin und seine herstellung und verwendungen. - Google Patents

Alpha-glycosylhesperidin und seine herstellung und verwendungen.

Info

Publication number: ATE124996T1
Authority: AT; Austria
Prior art keywords: hesperidin; alpha; glycosyl; foods; saccharide
Prior art date: 1989-06-03

Application number

AT90305944T

Other languages

English (en)

Inventor

Hiromi Hijiya

Toshio Miyake

Original Assignee

Hayashibara Biochem Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-03

Filing date

1990-05-31

Publication date

1995-07-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15302820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE124996(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-05-31 Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab

1995-07-15 Application granted granted Critical

1995-07-15 Publication of ATE124996T1 publication Critical patent/ATE124996T1/de

Links

239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 abstract 8
QUQPHWDTPGMPEX-UHFFFAOYSA-N Hesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(COC4C(C(O)C(O)C(C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-UHFFFAOYSA-N 0.000 abstract 8
QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 abstract 8
APSNPMVGBGZYAJ-GLOOOPAXSA-N clematine Natural products COc1cc(ccc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 APSNPMVGBGZYAJ-GLOOOPAXSA-N 0.000 abstract 8
229940025878 hesperidin Drugs 0.000 abstract 8
VUYDGVRIQRPHFX-UHFFFAOYSA-N hesperidin Natural products COc1cc(ccc1O)C2CC(=O)c3c(O)cc(OC4OC(COC5OC(O)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 VUYDGVRIQRPHFX-UHFFFAOYSA-N 0.000 abstract 8
ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 abstract 8
QUQPHWDTPGMPEX-QJBIFVCTSA-N hesperidin Chemical class C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]4[C@@H]([C@H](O)[C@@H](O)[C@H](C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-QJBIFVCTSA-N 0.000 abstract 5
235000013305 food Nutrition 0.000 abstract 3
125000002353 D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
241000208125 Nicotiana Species 0.000 abstract 1
235000002637 Nicotiana tabacum Nutrition 0.000 abstract 1
-1 alpha -glucosyl saccharide Chemical class 0.000 abstract 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
235000013361 beverage Nutrition 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000002537 cosmetic Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
230000009965 odorless effect Effects 0.000 abstract 1
230000001766 physiological effect Effects 0.000 abstract 1
239000004033 plastic Substances 0.000 abstract 1
229920003023 plastic Polymers 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
239000011347 resin Substances 0.000 abstract 1
229920005989 resin Polymers 0.000 abstract 1
230000009967 tasteless effect Effects 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1
229940088594 vitamin Drugs 0.000 abstract 1
239000011782 vitamin Substances 0.000 abstract 1
229930003231 vitamin Natural products 0.000 abstract 1
235000013343 vitamin Nutrition 0.000 abstract 1
150000003722 vitamin derivatives Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/771—Organic compounds containing hetero rings
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/346—Finished or semi-finished products in the form of powders, paste or liquids
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/75—Fixation, conservation, or encapsulation of flavouring agents the flavouring agents being bound to a host by chemical, electrical or like forces, e.g. use of precursors
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/16—Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
- A23G2200/04—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing vitamins, antibiotics, other medicaments
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Wood Science & Technology (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Birds (AREA)
General Engineering & Computer Science (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Nutrition Science (AREA)
Molecular Biology (AREA)
Animal Husbandry (AREA)
Toxicology (AREA)
Inorganic Chemistry (AREA)
Mycology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Hematology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Obesity (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT90305944T 1989-06-03 1990-05-31 Alpha-glycosylhesperidin und seine herstellung und verwendungen. ATE124996T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1141902A JP3060227B2 (ja)	1989-06-03	1989-06-03	α―グリコシルヘスペリジンとその製造方法並びに用途

Publications (1)

Publication Number	Publication Date
ATE124996T1 true ATE124996T1 (de)	1995-07-15

Family

ID=15302820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90305944T ATE124996T1 (de)	1989-06-03	1990-05-31	Alpha-glycosylhesperidin und seine herstellung und verwendungen.

Country Status (10)

Country	Link
US (2)	US5627157A (de)
EP (1)	EP0402049B1 (de)
JP (1)	JP3060227B2 (de)
KR (2)	KR0153529B1 (de)
AT (1)	ATE124996T1 (de)
CA (1)	CA2018085C (de)
DE (1)	DE69020810T2 (de)
DK (1)	DK0402049T3 (de)
ES (1)	ES2078308T3 (de)
GR (1)	GR3017492T3 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2926432B2 (ja) *	1990-06-11	1999-07-28	株式会社林原生物化学研究所	養毛剤
HUT66558A (en) *	1991-11-18	1994-12-28	Merrell Dow Pharma	Phosphorylated flavonoids in the treatment of viral diseases
JPH0725761A (ja) *	1993-07-09	1995-01-27	Kureha Chem Ind Co Ltd	軟骨保護剤
DE4444238A1 (de) *	1994-12-13	1996-06-20	Beiersdorf Ag	Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden
JP3833775B2 (ja) *	1996-06-26	2006-10-18	株式会社林原生物化学研究所	酵素処理ヘスペリジンおよびその製造方法ならびに酵素処理ヘスペリジンの使用方法
DE69821428T2 (de) *	1997-03-24	2004-12-16	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Verfahren zur herstellung einer alpha-monoglucosylhesperidin-reichen substanz
US6224872B1 (en)	1997-07-31	2001-05-01	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Composition
JP4295840B2 (ja) *	1997-12-09	2009-07-15	株式会社林原生物化学研究所	血行改善剤
JP4203159B2 (ja)	1997-12-09	2008-12-24	株式会社林原生物化学研究所	神経機能調節剤
EP0956867A1 (de) *	1998-05-12	1999-11-17	Franz-Peter Dr. Liebel	Verwendung von Flavonoidglykosiden, Gerbstoffen und Mikroorganismen zur Therapie und Prophylaxe des Diabetes mellitus
KR20000019716A (ko) *	1998-09-15	2000-04-15	박호군	바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
JP2001158796A (ja) *	1999-11-30	2001-06-12	Toyo Seito Kk	α−グルコシルジオスミンの製造方法及びフラボノイド組成物
KR20010064389A (ko) *	1999-12-29	2001-07-09	서경배	민감성 피부용 화장료 조성물
AUPQ598300A0 (en)	2000-03-03	2000-03-23	Citrus Sensation Pty Ltd	Citrus fruit preservative
AU781514B2 (en) *	2000-03-03	2005-05-26	Citrus Sensation Pty Ltd	Fruit and vegetable preservative
US6989161B2 (en) *	2000-06-12	2006-01-24	Access Business Group International Llc	Phytonutrient nutritional supplement
US6514506B1 (en) *	2001-02-14	2003-02-04	Color Access, Inc.	Whitening compositions containing ascomycete derived enzyme
CN100381436C (zh) *	2001-03-15	2008-04-16	科学技术振兴事业集团	类黄酮化合物及其制造方法
FR2836042B1 (fr) *	2002-02-15	2004-04-02	Sederma Sa	Compositions cosmetiques ou dermopharmaceutiques pour diminuer les poches et cernes sous les yeux
JP4147038B2 (ja) *	2002-03-01	2008-09-10	サラヤ株式会社	味質改善された羅漢果配糖体およびその製造方法
US20050215493A1 (en) *	2002-05-01	2005-09-29	Masaki Miyake	Calcium-containing tissue strengthening agents and use thereof
US20040149375A1 (en) *	2003-02-05	2004-08-05	Shun-Ming Huang	Method for encapsulating a secondary battery
EP1731134B1 (de)	2004-03-17	2015-10-07	Hayashibara Co., Ltd.	Funktionale pulver
JP4731835B2 (ja) *	2004-06-07	2011-07-27	東洋精糖株式会社	低臭気酵素処理ヘスペリジン組成物
US20060018861A1 (en) *	2004-07-23	2006-01-26	Minghua Chen	Skin care composition
CN1988882A (zh) *	2004-07-23	2007-06-27	宝洁公司	基于基底的护肤制品
EP1771149A1 (de) *	2004-07-23	2007-04-11	The Procter and Gamble Company	Hautpflegezusammensetzung mit einem flavonoid und vitamin b3
EP1833456A1 (de) *	2004-07-23	2007-09-19	The Procter and Gamble Company	Hautpflegezusammensetzung mit einem flavonoid und vitamin b3
EP1778177A1 (de) *	2004-07-23	2007-05-02	The Procter and Gamble Company	Hautpflegezusammensetzungen mit einem flavonoid und vitamin b3
US20080305054A1 (en) *	2004-10-25	2008-12-11	Symrise Gmbh & Co. Kg	Use of Glycosylated Flavanones for the Browning of Skin or Hair
KR101356330B1 (ko)	2004-12-24	2014-01-27	가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조	간기능 개선제
JP2006327945A (ja) *	2005-05-23	2006-12-07	Sanei Gen Ffi Inc	新規なフラボノイド配糖体
KR100736901B1 (ko)	2005-07-04	2007-07-06	광동제약 주식회사	진피연조엑스의 지표성분인 헤스페리딘과베타-시클로덱스트린의 포접화합물을 함유한 한방액제 및이의 제조방법
US7291340B2 (en) *	2005-12-29	2007-11-06	Elc Management Llc	Extracts from black yeast for whitening skin
PL1856988T3 (pl) *	2006-05-19	2018-02-28	Kraft Foods R & D, Inc.	Sposób wytwarzania i stosowania wyrobów z dodatkiem cukru flawonoidowego
JP2009007336A (ja) *	2007-05-25	2009-01-15	Shiseido Co Ltd	α−グリコシルヘスペリジンを含有する経口投与・摂取用の、メラニン低下剤、皮膚明度低下抑制剤、皮膚粘弾性低下抑制剤、皮脂量低下抑制剤、ＳＣＦ産生抑制剤、およびかゆみ抑制剤
JP2009007313A (ja) *	2007-06-29	2009-01-15	Lion Corp	筋萎縮抑制剤
US7862822B2 (en) *	2007-09-25	2011-01-04	Elc Management Llc	Extracts from black yeast for whitening skin
JP2010265215A (ja) *	2009-05-14	2010-11-25	Hayashibara Biochem Lab Inc	メチオニナーゼ阻害剤
JP5653602B2 (ja) *	2009-09-02	2015-01-14	東洋精糖株式会社	高吸収性薬剤組成物およびその製造方法
JP5837847B2 (ja) *	2011-03-04	2015-12-24	第一三共ヘルスケア株式会社	セチリジン塩酸塩を含有する医薬組成物
WO2013018779A1 (ja) *	2011-08-01	2013-02-07	株式会社林原	α－グルコシルヘスペリジンの結晶とその用途
JP5858686B2 (ja) *	2011-08-25	2016-02-10	花王株式会社	難水溶性ポリフェノール類の糖付加物の製造方法
JP6116869B2 (ja) *	2012-01-17	2017-04-19	花王株式会社	経口紫外線抵抗性向上剤
JP5985229B2 (ja) *	2012-04-11	2016-09-06	花王株式会社	難水溶性ポリフェノール類の糖付加物の製造方法
KR101488761B1 (ko) *	2012-05-22	2015-02-04	(주)제주사랑농수산	온주 밀감 미숙과 추출물을 이용한 콜라겐 생성 촉진용 조성물 및 자외선 차단용 조성물
JP6200310B2 (ja) *	2012-12-26	2017-09-20	花王株式会社	容器詰飲料
TWI673282B (zh)	2014-03-03	2019-10-01	日商林原股份有限公司	醣苷基柑果苷素與其製造方法以及用途
WO2016027837A1 (ja) *	2014-08-20	2016-02-25	株式会社林原	経口美容剤
JP6624630B2 (ja) *	2015-07-24	2019-12-25	織田　次男	化粧品類の製造方法
US10568827B2 (en) *	2015-09-02	2020-02-25	Hayashibara Co., Ltd.	External dermal agent for reducing yellowish dullness
US20220401761A1 (en) *	2019-10-30	2022-12-22	Toyo Sugar Refining Co., Ltd.	Skin External Preparation for Cellulite Improvement and Cellulite Improvement Method
JP7454980B2 (ja) *	2020-03-25	2024-03-25	東洋精糖株式会社	コラゲナーゼ活性阻害剤
JP7651278B2 (ja) *	2020-09-10	2025-03-26	トヨタ自動車株式会社	抗ストレス用食品組成物
WO2022107735A1 (ja) *	2020-11-17	2022-05-27	株式会社林原	水晶体硬度調節剤
JP2023170283A (ja) *	2022-05-18	2023-12-01	株式会社林原	内服用組成物
KR102806440B1 (ko) *	2022-07-29	2025-05-12	이경애	모노-글루코실헤스페리딘의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2700047A (en) *	1951-06-16	1955-01-18	Sunkist Growers Inc	Aqueous hydrolysis of flavanone glycosides
JPS548752B1 (de) *	1971-02-19	1979-04-18
JPS5432073A (en) *	1977-08-17	1979-03-09	Hitachi Ltd	Manufacture of cooling body
JPS5854799A (ja) *	1981-09-27	1983-03-31	Nitto Electric Ind Co Ltd	スピ−カ−キヤビネツト板材
JPS5899498A (ja) *	1981-12-04	1983-06-13	Dai Ichi Seiyaku Co Ltd	フラボノ−ル配糖体
US4521410A (en) *	1984-05-03	1985-06-04	The General Hospital Corporation	Vitamin D glycosyl orthoesters
DE69016800T2 (de) *	1989-03-08	1995-07-20	Hayashibara Biochem Lab	Herstellung und Verwendungen von alpha-Glycosylrutin.
JP2832848B2 (ja) *	1989-10-21	1998-12-09	株式会社林原生物化学研究所	結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途
JP3134233B2 (ja) *	1991-07-26	2001-02-13	株式会社林原生物化学研究所	α−グリコシルケルセチンとその製造方法並びに用途
JPH0899498A (ja) *	1994-09-30	1996-04-16	Pentel Kk	自動描画装置

1989
- 1989-06-03 JP JP1141902A patent/JP3060227B2/ja not_active Expired - Lifetime
1990
- 1990-05-31 AT AT90305944T patent/ATE124996T1/de not_active IP Right Cessation
- 1990-05-31 DK DK90305944.2T patent/DK0402049T3/da active
- 1990-05-31 EP EP90305944A patent/EP0402049B1/de not_active Expired - Lifetime
- 1990-05-31 DE DE69020810T patent/DE69020810T2/de not_active Expired - Lifetime
- 1990-05-31 ES ES90305944T patent/ES2078308T3/es not_active Expired - Lifetime
- 1990-06-01 CA CA002018085A patent/CA2018085C/en not_active Expired - Lifetime
- 1990-06-04 KR KR1019900008191A patent/KR0153529B1/ko not_active Expired - Lifetime
1994
- 1994-11-28 US US08/348,146 patent/US5627157A/en not_active Expired - Lifetime
1995
- 1995-07-12 US US08/501,656 patent/US5652124A/en not_active Expired - Fee Related
- 1995-09-21 GR GR950402609T patent/GR3017492T3/el unknown
1998
- 1998-08-25 KR KR1019980034394A patent/KR0184244B1/ko not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR0184244B1 (ko)	1999-05-01
DE69020810T2 (de)	1996-01-04
ES2078308T3 (es)	1995-12-16
DE69020810D1 (de)	1995-08-17
DK0402049T3 (da)	1995-08-21
KR910000784A (ko)	1991-01-29
GR3017492T3 (en)	1995-12-31
KR0153529B1 (ko)	1998-10-15
EP0402049A3 (de)	1991-03-20
EP0402049A2 (de)	1990-12-12
CA2018085C (en)	1999-04-27
JPH037593A (ja)	1991-01-14
CA2018085A1 (en)	1990-12-03
US5652124A (en)	1997-07-29
US5627157A (en)	1997-05-06
EP0402049B1 (de)	1995-07-12
JP3060227B2 (ja)	2000-07-10

Legal Events

Date	Code	Title	Description
1996-02-15	UEP	Publication of translation of european patent specification
1997-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69020810D1 (de)	1995-08-17	Alpha-Glycosylhesperidin und seine Herstellung und Verwendungen.
ATE135362T1 (de)	1996-03-15	Alpha-glycosyl-naringin, seine herstellung und seine verwendung
DE69016800D1 (de)	1995-03-23	Herstellung und Verwendungen von alpha-Glycosylrutin.
ATE135361T1 (de)	1996-03-15	4g-alpha-d-glukopyranosyl-rutin, seine herstellung und verwendungen
DE69023934D1 (de)	1996-01-18	Substanz PF 1022, Verfahren zu ihrer Herstellung und diese Substanz enthaltende anthelmintische Zusammensetzung.
PT1088823E (pt)	2005-03-31	Material acrilico
DE69431839D1 (de)	2003-01-16	Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden
DE69116791D1 (de)	1996-03-14	Lactoneotrehalose, und ihre Herstellung und Verwendung
LV12443A (en)	2000-03-20	7-(2-Aminoethyl)-benzothiazolones
DE69409141D1 (de)	1998-04-30	Zusammensetzung auf Basis von Stärke
IE883003L (en)	1989-04-05	Pyridine derivatives and related intermediates
EP0799827A4 (de)	1998-01-28	Acrylamid-derivate und verfahren zur herstellung
FR2654102B1 (fr)	1992-01-10	Procede de synthese de derives polyazotes cycliques.
GR3017577T3 (en)	1995-12-31	New anticancer antibiotic substance, the production and uses thereof.
HU904667D0 (en)	1991-01-28	Process for producing s-substituted thioacrryl-amides
ATE62248T1 (de)	1991-04-15	Ein doxorubicinderivat, ein verfahren zu dessen herstellung, pharmazeutische zusammensetzungen und dessen verwendung fuer die herstellung von arzneimitteln.
JPS5645498A (en)	1981-04-25	Manufacture of 66aminoo66desoxyy2*33oo isopropylideneealphaall sorbofuranose derivative and novel intermediate product
GR3001799T3 (en)	1992-11-23	Process for preparation of n-allyl-piperidine derivatives
AU2749688A (en)	1989-07-06	Process for the preparation of dialkylaminoethylamines
MA21919A1 (fr)	1991-04-01	Synthese asymetrique des derives de la furo [3,4-c] pyrydine
ATE154394T1 (de)	1997-06-15	Fermentations-ausgangsmaterial
SU1663928A1 (ru)	1994-11-15	Гемиглутарат 3-бензиламино-4-окси-n-бензилбутанамида, проявляющий местно-анестезирующую активность
SU1432968A3 (ru)	1994-03-15	Способ получения высокомеченного тритием пролина
GB8916844D0 (en)	1989-09-06	Synthesis of organic chemicals by enzyme catalysis
GB8817109D0 (en)	1988-08-24	Synthesis of organic chemicals by enzyme catalysis