ATE125530T1 - Neue indol- und indolin-verbindungen. - Google Patents

Neue indol- und indolin-verbindungen.

Info

Publication number: ATE125530T1
Authority: AT; Austria
Prior art keywords: alkyl; indoline compounds; new indole; compounds; phenyl
Prior art date: 1990-09-18

Application number

AT91308365T

Other languages

English (en)

Inventor

Jeremy Gilmore

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-18

Filing date

1991-09-12

Publication date

1995-08-15

1991-09-12 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1995-08-15 Application granted granted Critical

1995-08-15 Publication of ATE125530T1 publication Critical patent/ATE125530T1/de

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
150000002476 indolines Chemical class 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000000008 (C1-C10) alkyl group Chemical class 0.000 abstract 1
125000006374 C2-C10 alkenyl group Chemical class 0.000 abstract 1
239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Immunology (AREA)
Dermatology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT91308365T 1990-09-18 1991-09-12 Neue indol- und indolin-verbindungen. ATE125530T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909020338A GB9020338D0 (en)	1990-09-18	1990-09-18	Pharmaceutical compounds

Publications (1)

Publication Number	Publication Date
ATE125530T1 true ATE125530T1 (de)	1995-08-15

Family

ID=10682362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91308365T ATE125530T1 (de)	1990-09-18	1991-09-12	Neue indol- und indolin-verbindungen.

Country Status (10)

Country	Link
US (1)	US5185361A (de)
EP (1)	EP0476935B1 (de)
JP (1)	JP3046861B2 (de)
AT (1)	ATE125530T1 (de)
CA (1)	CA2051460C (de)
DE (1)	DE69111541T2 (de)
DK (1)	DK0476935T3 (de)
ES (1)	ES2076477T3 (de)
GB (1)	GB9020338D0 (de)
GR (1)	GR3017390T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4400597A (en) *	1996-10-08	1998-05-05	Fujisawa Pharmaceutical Co., Ltd.	Indole derivatives
AU745081B2 (en) *	1997-06-27	2002-03-14	Fujisawa Pharmaceutical Co., Ltd.	Sulfonamide compounds and medicinal use thereof
US7229986B2 (en)	2000-05-16	2007-06-12	Takeda Pharmaceutical Company Ltd.	Melanin-concentrating hormone antagonist
WO2004037251A1 (en) *	2002-10-24	2004-05-06	Sterix Limited	Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2
GB0224830D0 (en)	2002-10-24	2002-12-04	Sterix Ltd	Compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4448784A (en) *	1982-04-12	1984-05-15	Hoechst-Roussel Pharmaceuticals, Inc.	1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof
GB8524157D0 (en) *	1984-10-19	1985-11-06	Ici America Inc	Heterocyclic amides
GB8707051D0 (en) *	1986-04-15	1987-04-29	Ici America Inc	Heterocyclic carboxamides
GB8927981D0 (en) *	1989-12-11	1990-02-14	Ici Plc	Carbamoyl derivative

1990
- 1990-09-18 GB GB909020338A patent/GB9020338D0/en active Pending
1991
- 1991-09-12 DE DE69111541T patent/DE69111541T2/de not_active Expired - Fee Related
- 1991-09-12 DK DK91308365.5T patent/DK0476935T3/da active
- 1991-09-12 ES ES91308365T patent/ES2076477T3/es not_active Expired - Lifetime
- 1991-09-12 EP EP91308365A patent/EP0476935B1/de not_active Expired - Lifetime
- 1991-09-12 AT AT91308365T patent/ATE125530T1/de not_active IP Right Cessation
- 1991-09-16 CA CA002051460A patent/CA2051460C/en not_active Expired - Fee Related
- 1991-09-17 JP JP3236530A patent/JP3046861B2/ja not_active Expired - Lifetime
- 1991-09-18 US US07/761,587 patent/US5185361A/en not_active Expired - Lifetime
1995
- 1995-09-13 GR GR950402508T patent/GR3017390T3/el unknown

Also Published As

Publication number	Publication date
EP0476935B1 (de)	1995-07-26
JP3046861B2 (ja)	2000-05-29
GB9020338D0 (en)	1990-10-31
CA2051460C (en)	2002-01-22
DK0476935T3 (da)	1995-09-11
ES2076477T3 (es)	1995-11-01
EP0476935A1 (de)	1992-03-25
JPH04230661A (ja)	1992-08-19
GR3017390T3 (en)	1995-12-31
CA2051460A1 (en)	1992-03-19
DE69111541T2 (de)	1996-01-18
US5185361A (en)	1993-02-09
DE69111541D1 (de)	1995-08-31

Legal Events

Date	Code	Title	Description
1996-01-15	UEP	Publication of translation of european patent specification
2004-06-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0478954T3 (da)	2001-01-08	Serotonin 5HT1A- og 5HT1D-antagonister
ES2131463B1 (es)	2000-03-01	Derivados de ciclopropilglicina con propiedades farmaceuticas.
FI930970A0 (fi)	1993-03-04	Imidazolderivat med bifenylsulfonylurea- eller bifenylsulfonyluretansidokedja, foerfaranden foer framstaellning av dessa och anvaendning av dessa
DK0595610T3 (da)	1997-08-25	Benzokondenserede lactamer
ATE240734T1 (de)	2003-06-15	Zubereitung von xanthinderivaten als feste dispersion
NO931917L (no)	1993-11-30	Farmas!ytiske forbindelser
ATE69815T1 (de)	1991-12-15	Neue nitromethylen-derivate.
ES2184960T3 (es)	2003-04-16	Nuevas pirimidin-4-onas-(5,6)-heteroaril condensadas 2,3 disustituidas.
DK0902018T3 (da)	2008-10-20	2-(arylpheny)amino-imidazolinderivater
DK0747392T3 (da)	2001-01-29	Dobbeltvirkende inhibitorer indeholdende 1,2-diazepiner
ATE125530T1 (de)	1995-08-15	Neue indol- und indolin-verbindungen.
ID25477A (id)	2000-10-05	Turunan-turunan spiropiperidin
DK0481756T3 (da)	1998-02-16	Benzamidderivater
ATE116974T1 (de)	1995-01-15	5- piperazinylalkyl-1,5-benzothiazepinone verwendbar als calciumantagonisten.
FI962768A0 (fi)	1996-07-05	N-(2-ftaali-imidoetyyli)substituoituja transpiperidiini-2,5-dikarboksylaatteja
DK384388D0 (da)	1988-07-08	Herbicid
ATE79540T1 (de)	1992-09-15	Pharmazeutische zusammensetzung.
DK158729C (da)	1990-11-19	N-(3-trifluormethylphenyl)-n'-propargylpiperazin, farmaceutiske praeparater, der indeholder det, dets anvendelse, samt en fremgangsmaade til fremstilling af et farmaceutisk praeparat
ATE207879T1 (de)	2001-11-15	Alkynylaminosäure derivate und ihre verwendung als pharmazeutische verbindungen
FI905664A0 (fi)	1990-11-15	Glutarsyraderivat och deras framstaellningsfoerfaranden.
PE59699A1 (es)	1999-06-16	2,4 diaminopirimidina sustituida
DK0539330T3 (da)	1995-07-17	Fremgangsmåde til fremstilling af substituerede indoler
DK221786A (da)	1986-11-15	Phosphorimidater, deres fremstilling og anvendelse til bekaempelse af insekter, mider og nematoder
FI942247A0 (fi)	1994-05-13	Trisyklo(3.3.1.13.7)dek-2-yyli(R(R*,R))-3-(1H-indol-3-yylimetyyli)-3-metyyli-4,9-diokso-7,11-difenyyli-10-oksa-2,5,8-triatsaundekanaatin synteesi